Di Natale C, La Manna S, Avitabile C, Florio D, Morelli G, Netti PA, Marasco D
Corrigendum to "Engineered β-hairpin scaffolds from human prion protein regions: Structural and functional investigations of aggregates" [Bioorg. Chem. 96 (2020) 103594]
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2020 Jun; 99: 103853-103853.

Di Natale C, La Manna S, Avitabile C, Florio D, Morelli G, Netti PA, Marasco D
Engineered β-hairpin scaffolds from human prion protein regions: Structural and functional investigations of aggregates
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2020 Mar; 96: 103594-103594.

Lanza V, Milardi D, Di Natale G, Pappalardo G
Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases
Curr Med Chem (ISSN: 1875-533xelectronic, 0929-8673linking), 2018 Feb 12; 25(4): 525-539.

Lanza V, Bellia F, Rizzarelli E
An inorganic overview of natural Aβ fragments: Copper(II) and zinc(II)-mediated pathways
Coord Chem Rev (ISSN: 0010-8545), 2018; 369: 1-14.

Magri A, Pietropaolo A, Tabbì G, La Mendola D, Rizzarelli E
From Peptide Fragments to Whole Protein: Copper(II) Load and Coordination Features of IAPP
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Dec 19; 23(71): 17898-17902.

Sgarlata C, Arena G, Bonomo RP, Giuffrida A, Tabbì G
Simple and mixed complexes of copper(II) with 8-hydroxyquinoline derivatives and amino acids: Characterization in solution and potential biological implications
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2017 Dec 8; 180: 89-100.

Dell'Acqua S, Bacchella C, Monzani E, Nicolis S, Di Natale G, Rizzarelli E, Casella L
Prion Peptides Are Extremely Sensitive to Copper Induced Oxidative Stress
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2017 Sep 18; 56(18): 11317-11325.

Di Natale G, Bellia F, Sciacca F, Campagna T, Pappalardo G
Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-beta aggregation
Inorganica Chimica Acta, 2017 Sep; N/D: N/D-N/D.

Grasso GI, Bellia F, Arena G, Satriano C, Vecchio G, Rizzarelli E
Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2017 Jul 28; 135: 447-457.

Lanza V, Travaglia A, Malgieri G, Fattorusso R, GrassoG, Di Natale G, Zito V, Arena G, Milardi D, Rizzarelli E
Ubiquitin Associates with the N-Terminal Domain of Nerve Growth Factor: The Role of Copper(II) Ions
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Dec 05; 22(49): 17767-17775.

Santoro AM, Monaco I, Attanasio F, Lanza V, Pappalardo G, Tomasello MF, Cunsolo A, Rizzarelli E, De Luigi A, Salmona M, Milardi D
Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2016 Sep 16; 6: 33444-33444.

Magrì A, Tabbì G, Giuffrida A, Pappalardo  G, Satriano C, Naletova I, Nicoletti VG, Attanasio F
Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2016 Aug 27; 164: 59-69.

Pizzanelli S, Forte C, Pinzino C, Magrì A, La Mendola D
Copper(ii) complexes with peptides based on the second cell binding site of fibronectin: metal coordination and ligand exchange kinetics
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic), 2016 Feb 7; 18(5): 3982-3994.

Di Natale G, Sinopoli A, Grenacs A, Sanna D, Sovago I, Pappalardo G
Copper(II) coordination properties of the Abeta(1-16)2 peptidomimetic: an experimental evidence of intermolecular macrochelate complex species in the abeta dimer
New J Chem, 2016; 40: 10274-10284.

Di Natale G, Turi I, Pappalardo G, Sóvágó I, Rizzarelli E
Cross-Talk Between the Octarepeat Domain and the Fifth Binding Site of Prion Protein Driven by the Interaction of Copper(II) with the N-terminus
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Mar 2; 21(10): 4071-4084.

Tabbì G, Magrì A, Giuffrida A, Lanza V, Pappalardo  G, Naletova I, Nicoletti VG, Attanasio F, Rizzarelli E
Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015 Jan; 142: 39-46.

Benetti F, Biarnés X, Attanasio F, Giachin G, Rizzarelli E, Legname G
Structural determinants in prion protein folding and stability
J Mol Biol (ISSN: 0022-2836, 1089-8638, 0022-2836linking), 2014 Nov 11; 426(22): 3796-3810.

Sinopoli A, Magri A, Milardi D, Pappalardo M, Pucci P, Flagiello A, Titman JJ, Nicoletti VG, Caruso G, Pappalardo G, GrassoG
The role of copper(II) in the aggregation of human amylin
Metallomics (ISSN: 1756-5901, 1756-591x), 2014 Oct; 6(10): 1841-1852.

La Mendola D, Rizzarelli E
Evolutionary implications of metal binding features in different species' prion protein: an inorganic point of view
Biomolecules (ISSN: 2218-273x), 2014 May 23; 4(2): 546-565.

Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 56-63.

GrassoG, Magrì A, Bellia F, Pietropaolo A, La Mendola D, Rizzarelli E
The Copper (ii) And Zinc (ii) Coordination Mode Of Hexxh And Hxxeh Motif In Small Peptides: The Role Of Carboxylate Location And Hydrogen Bonding Network
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Jan; 130(1): 92-102.

Bellia F, GrassoG
The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2014; 49(4): 274-279.

Bellia F, Oliveri V, Rizzarelli E, Vecchio G
New derivative of carnosine for nanoparticle assemblies
Eur J Med Chem (ISSN: 1768-3254, 0223-5234, 1768-3254electronic), 2013 Dec; 70: 225-232.

Tabbì G, Giuffrida A, Bonomo RP
Determination Of Formal Redox Potentials In Aqueous Solution Of Copper(ii) Complexes With Ligands Having Nitrogen And Oxygen Donor Atoms And Comparisonwith Their Epr And Uv–vis Spectral Features
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2013 Nov; 128: 137-145.

Turi I, DSanna D, Garribba E, Pappalardo G, Sóvágó I
The effect of non-coordinating side chains on the metal binding affinities of peptides of histidine
Polyhedron (ISSN: 0277-5387), 2013 Oct 7; 62: 7-17.

De Simonea A, Stanzione F, Marasco D, Vitagliano L, Esposito L
The Intrinsic Stability Of The Human Prion Beta-Sheet Region Investigated By Molecular Dynamics
Journal Of Biomolecular Structure & Dynamics, 2013 May 1; 31(5): 441-452.

Di Natale G, Osz K, Kállay C, Pappalardo G, Sanna D, Impellizzeri G, Sóvágó I, Rizzarelli E
Affinity, speciation, and molecular features of copper(II) complexes with a prion tetraoctarepeat domain in aqueous solution: insights into old and new results
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2013 Mar 11; 19(11): 3751-3761.

Attanasio F, De Bona P, Cataldo S, Sciacca MFM, Milardi D, Pignataro B, Pappalardo G
Copper(II) and zinc(II) dependent effects on A beta 42 aggregation: a CD, Th-T and SFM study
New J Chem (ISSN: 1144-0546), 2013; 37(4): 1206-1215.

Arena G, La Mendola D, Pappalardo G, Sovago I, Rizzarelli E
Interactions of Cu 2+ with prion family peptide fragments: Considerations on affinity, speciation and coordination
Coord Chem Rev (ISSN: 0010-8545), 2012 Oct; 256(19-20): 2202-2218.

Roviello GN, Mottola A, Musumeci D, Bucci EM, Pedone C
Synthesis and aggregation properties of a novel enzymatically resistant nucleoamino acid
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Oct; 43(4): 1465-1470.

Magrì A, D'Alessandro F, Di Stefano DA, Campagna T, Pappalardo G, Impellizzeri G, La Mendola D
Copper(ii) Coordination Properties Of The Integrin Ligand Sequence Phsrn And Its New Beta-Cyclodextrin Conjugates
Journal Of Inorganic Biochemistry, 2012 Sep; 113: 15-24.

La Mendola D, Magrì A, Santoro AM, Nicoletti VG, Rizzarelli E
Copper(II) interaction with peptide fragments of histidine-proline-rich glycoprotein: Speciation, stability and binding details
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jun; 111: 59-69.

La Mendola D, Farkas D, Bellia F, Magri A, Travaglia A, Hansson O, Rizzarelli E
Probing the copper(II) binding features of angiogenin. Similarities and differences between a N-terminus peptide fragment and the recombinant human protein
Inorg Chem (ISSN: 1520-510x, 0020-1669, 1520-510xelectronic), 2012 Jan 2; 51(1): 128-141.

Arena G, Pappalardo G, Sovago I, Rizzarelli E
Copper(ii) Interaction With Amyloid-Beta: Affinity And Speciation
Coord Chem Rev (ISSN: 0010-8545), 2012 Jan; 256(1-2): 3-12.

Kállay C, Dávid A, Timári S, Nagy EM, Sanna D, Garribba E, Micera G, De Bona P, Pappalardo G, Rizzarelli E, Sóvágó I
Copper(II) complexes of rat amylin fragments
Dalton T (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2011 Oct 14; 40(38): 9711-9721.

Grasso GI, Arena G, Bellia F, Maccarrone G, Parrinello M, Pietropaolo A, Vecchio G, Rizzarelli E
Intramolecular weak interactions in the thermodynamic stereoselectivity of copper(II) complexes with carnosine-trehalose conjugates
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Sep 16; 17(34): 9448-9455.

Grasso GI, Bellia F, Arena G, Vecchio G, Rizzarelli E
Noncovalent interaction-driven stereoselectivity of copper(II) complexes with cyclodextrin derivatives of L- and D-carnosine
Inorg Chem (ISSN: 1520-510x, 0020-1669, 1520-510xelectronic), 2011 Jun 6; 50(11): 4917-4924.

Benetti F, Biarnes X, Attanasio F, Rizzarelli E, Laio A, Legname G
Description and Characterization of a Highly Stable Enthalpic Intermediate State in Mouse Prion Protein Folding
Prion (ISSN: 1933-6896), 2011 Apr; 5: N/D-N/D.

Kállay C, Turi I, Timári S, Nagy Z, Sanna D, Pappalardo G, De Bona P, Rizzarelli E, Sóvágó I
The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106-114 region of human prion protein
Monatshefte Fur Chemie (ISSN: 0026-9247), 2011 Apr; 142(4): 411-419.

Vagliasindi LI, Arena G, Bonomo RP, Pappalardo G, Tabbì G
Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2011 Mar 21; 40(11): 2441-2450.

Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E
Copper(I) and Copper(II) Inhibit A beta Peptides Proteolysis by Insulin-Degrading Enzyme Differently: Implications for Metallostasis Alteration in Alzheimer's Disease
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Feb 25; 17(9): 2752-2762.

Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.

La Mendola D, Magrì A, Vagliasindi LI, Hansson Ö, Bonomo RP, Rizzarelli E
Copper(II) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin
Dalton T (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2010 Nov 28; 39(44): 10678-10684.

Di Natale G, Pappalardo G, Milardi D, Sciacca MF, Attanasio F, La Mendola D, Rizzarelli E
Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: The role of copper(II) ions, pH, and membrane mimicking environments
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Nov 4; 114(43): 13830-13838.

Józsa E, Osz K, Kállay C, de Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sóvágó I
Nickel(ii) and mixed metal complexes of amyloid-β N-terminus
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010 Sep 14; 39(30): 7046-7053.

Turi I, Kállay C, Szikszai D, Pappalardo G, Di Natale G, De Bona P, Rizzarelli E, Sóvágó I
Nickel(II) complexes of the multihistidine peptide fragments of human prion protein
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2010 Sep; 104(8): 885-891.

Benetti F, Pastorino L, Attanasio F, Rizzarelli E, Legname G
Insights into Prion Protein Stability
Prion (ISSN: 1933-6896), 2010 Jul; 4(3): N/D-N/D.

La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E
A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2010 Jun 1; 16(21): 6212-6223.

Di Natale G, Pappalardo G, Milardi D, Sciacca MFM, Attanasio F, La Mendola D, Rizzarelli E
Different Interactions Of Human And Avian Prion Proteins N-Terminal Tandem Repeat Peptides And Their Copper (ii) Complexes With Model Membranes
Journal Of Chemical Physics, 2010; 114: 13830-13838.

Arnesano F, Scintilla S, Calò V, Bonfrate E, Ingrosso C, Losacco M, Pellegrino T, Rizzarelli E, Natile G
Copper-triggered aggregation of ubiquitin
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2009 Sep 16; 4(9): e7052-e7052.

Palladino P, Ronga L, Benedetti E, Rossi F, Ragone R
Peptide Fragment Approach to Prion Misfolding: The Alpha-2 Domain
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2009 Sep; 15(3): 165-176.

Pietropaolo A, Muccioli L, Zannoni C, Rizzarelli E
Conformational preferences of the full chicken prion protein in solution and its differences with respect to mammals
Chemphyschem (ISSN: 1439-7641, 1439-4235, 1439-7641electronic), 2009 Jul 13; 10(9-10): 1500-1510.

La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
Prion Proteins Leading to Neurodegeneration (vol 5, pg 579, 2008)
Current Alzheimer Research (ISSN: 1567-2050), 2009 Jun; 6(3): N/D-N/D.

Di Natale G, Osz K, Nagy Z, Sanna D, Micera G, Pappalardo G, Sovago I, Rizzarelli E
The Interaction Of Copper (ii) With The Prion Peptide Fragment Huprp (76-114) Encompassing Four Histidyl Residues Within And Outside The Octarepeat Domain
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2009 May 4; 48(9): 4239-4250.

La Mendola D, Magrì A, Hansson O, Bonomo RP, Rizzarelli E
Copper(II) complexes with peptide fragments encompassing the sequence 122-130 of human doppel protein
Journal Of Inorganic Biochemistry, 2009 May; 103(5): 758-765.

Bonomo RP, Di Natale G, Rizzarelli E, Tabbì G, Vagliasindi LI
Copper(II) complexes of prion protein PEG11-tetraoctarepeat fragment: spectroscopic and voltammetric studies
Dalton T (ISSN: 1477-9226, 1477-7922, 1477-9234), 2009 Apr 14; (14): 2637-2646.

La Mendola D, Bonomo RP, Caminati S, Di Natale G, Emmi SS, Hansson O, Maccarrone G, Pappalardo G, Pietropaolo A, Rizzarelli E
Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2009 Feb; 103(2): 195-204.

Ronga L, Palladino P, Ragone R, Benedetti E, Rossi F
A thermodynamic approach to the conformational preferences of the 180-195 segment derived from the human prion protein α2-helix
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009; 15(1): 30-35.

La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
Prion proteins leading to neurodegeneration
Current Alzheimer Research (ISSN: 1567-2050), 2008 Dec; 5(6): 579-590.

Di Natale G, Damante CA, Nagy Z, Osz K, Pappalardo G, Rizzarelli E, Sóvágó I
Copper(II) binding to two novel histidine-containing model hexapeptides: evidence for a metal ion driven turn conformation
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2008 Nov; 102(11): 2012-2019.

Bonomo RP, Pappalardo G, Rizzarelli E, Tabbì G, Vagliasindi LI
Studies of nitric oxide interaction with mono- and dinuclear copper(II) complexes of prion protein bis-octarepeat fragments
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2008 Sep 7; (29): 3805-3816.

Pappalardo M, Sciacca MFM, Milardi D, Grasso DM, La Rosa C
Thermodynamics Of Azurin Folding: The Role Of The Copper Ion
Journal Of Thermal Analysis And Calorimetry (ISSN: 1388-6150), 2008 Sep; 93(2): 575-581.

Bonomo RP, D'Alessandro F, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
Carcinine-beta-cyclodextrin derivatives as scavenger entities of (OH) radicals and SOD-like properties of their copper(II) complexes
Inorg Chim Acta (ISSN: 0020-1693), 2008 May 5; 361(6): 1705-1714.

Pietropaolo A, Muccioli L, Zannoni C, La Mendola D, Maccarrone G, Pappalardo G, Rizzarelli E
Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2008 Apr 24; 112(16): 5182-5188.

De Simone A, Pedone C, Vitagliano L
Structure, dynamics, and stability of assemblies of the human prion fragment SNQNNF
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2008 Feb 15; 366(3): 800-806.

Ronga L, Palladino P, Saviano G, Tancredi T, Benedetti E, Ragone R, Rossi F
Structural characterization of a neurotoxic threonine-rich peptide corresponding to the human prion protein α2-helical 180-195 segment and comparison with full-length α2-helix-derived peptides
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008; 14(10): 1096-1102.

Amorini AM, Bellia F, Di Pietro V, Giardina B, La Mendola D, Lazzarino G, Sortino S, Tavazzi B, Rizzarelli E, Vecchio G
Synthesis And Antioxidant Activity Of New Homocarnosine Beta-Cyclodextrin Conjugates
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2007 Jul; 42(7): 910-920.

Bonomo RP, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
Nitrogen oxide interaction with copper complexes formed by small peptides belonging to the prion protein octa-repeat region
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2007 Apr 14; (14): 1400-1408.

Bellia F, La Mendola D, Maccarrone G, Mineo P, Vitalini D, Scamporrino E, Sortino S, Vecchio G, Rizzarelli E
Copper(II) Complexes With Beta-Cyclodextrin-Homocarnosine Conjugates And Their Antioxidant Activity
Inorg Chim Acta (ISSN: 0020-1693), 2007 Feb 15; 360(3): 945-954.

Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.

Ronga L, Palladino P, Costantini S, Facchiano A, Ruvo M, Benedetti E, Ragone R, Rossi F
Conformational diseases and structure-toxicity relationships: Lessons from prion-derived peptides
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2007 Feb; 8(1): 83-90.

Rao M, Russo F, Granata V, Berisio R, Zagari A, Gianfreda L
Fate of prions in soil: Interaction of a recombinant ovine prion protein with synthetic humic-like mineral complexes
Soil Biol Biochem (ISSN: 0038-0717), 2007 Feb; 39(2): 493-504.

Osz K, Nagy Z, Pappalardo G, Di Natale G, Sanna D, Micera G, Rizzarelli E, Sóvágó I
Copper(II) interaction with prion peptide fragments encompassing histidine residues within and outside the octarepeat domain: speciation, stability constants and binding details
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2007; 13(25): 7129-7143.

Pappalardo M, Milardi D, Grasso D, La Rosa C
Steered molecular dynamics studies reveal different unfolding pathways of prions from mammalian and non-mammalian species
New J Chem (ISSN: 1144-0546), 2007; 31(6): 901-905.

Ronga L, Palladino P, Tizzano B, Marasco D, Benedetti E, Ragone R, Rossi F
Effect of salts on the structural behavior of hPrP α2-helix-derived analogues: The counterion perspective
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 790-795.

Esposito L, Pedone C, Vitagliano L
Molecular dynamics analyses of cross-beta-spine steric zipper models: beta-sheet twisting and aggregation
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2006 Sep 1; 103(31): 11533-11538.

Ronga L, Tizzano B, Palladino P, Ragone R, Urso E, Maffia M, Ruvo M, Benedetti E, Rossi F
The prion protein: structural features and related toxic peptides
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2006 Sep; 68(3): 139-147.

Joszal V, Nagy Z, Osz K, Sanna D, Di Natale G, La Mendola D, Pappalardo G, Rizzarelli E, Sovago I
Transition metal complexes of terminally protected peptides containing histidyl residues
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2006 Sep; 100(8): 1399-1409.

Langella E, Improta R, Crescenzi O, Barone V
Assessing the acid-base and conformational properties of histidine residues in human prion protein (125-228) by means of pKα calculations and molecular dynamics simulations
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Jul 1; 64(1): 167-177.

Granata V, Palladino P, Tizzano B, Negro A, Berisio R, Zagari A
The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Jun 15; 82(3): 234-240.

Palladino P, Ronga L, Tizzano B, Rossi F, Ragone R, Tancredi T, Saviano G, Facchiano A, Costantini S, Ruvo M, Benedetti E
Prion protein misfolding: Conformational stability of the alpha 2-helix
Understanding Biology Using Peptides, 2006; N/D: N/D-N/D.

Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Micera G, Osz K, Pappalardo G, Rizzarelli E, Sanna D, Sovago I
Environmental effects on a prion's helix II domain: copper(II) and membrane interactions with PrP180-193 and its analogues
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2005 Dec 23; 12(2): 537-547.

Di Natale G, Grasso G, Impellizzeri G, La Mendola D, Micera G, Mihala N, Nagy Z, Osz K, Pappalardo G, Rigó V, Rizzarelli E, Sanna D, Sóvágó I
Copper(II) interaction with unstructured prion domain outside the octarepeat region: Speciation, stability, and binding details of copper(II) complexes with PrP106-126 peptides
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2005 Oct 3; 44(20): 7214-7225.

Cucinotta V, Giuffrida A, Maccarrone G, Messina M, Puglisi A, Rizzarelli E, Vecchio G
Coordination properties of 3-functionalized β-cyclodextrins. Thermodynamic stereoselectivity of copper(II) complexes of the A, B-diamino derivative and its exploitation in LECE
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Sep 21; (16): 2731-2736.

La Mendola D, Bonomo RP, Impellizzeri G, Maccarrone G, Pappalardo G, Pietropaolo A, Rizzarelli E, Zito V
Copper(II) complexes with chicken prion repeats: Influence of proline and tyrosine residues on the coordination features
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2005 Sep; 10(5): 463-475.

Tizzano B, Palladino P, De Capua A, Marasco D, Rossi F, Benedetti E, Pedone C, Ragone R, Ruvo M
The Human Prion Protein Alpha2 Helix: A Thermodynamic Study Of Its Conformational Preferences
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2005 Apr 1; 59(1): 72-79.

Di Natale G, Impellizzeri G, Pappalardo G
Conformational properties of peptide fragments homologous to the 106-114 and 106-126 residues of the human prion protein: a CD and NMR spectroscopic study
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2005 Feb 7; 3(3): 490-497.

Bonomo RP, Cucinotta V, Giuffrida A, Impellizzeri G, Magrì A, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
A re-investigation of copper coordination in the octa-repeats region of the prion protein
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Jan 7; (1): 150-158.

Langella E, Improta R, Barone V
Checking the pH-induced conformational transition of prion protein by molecular dynamics simulations: Effect of protonation of histidine residues
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2004 Dec; 87(6): 3623-3632.

Arena G, Bonomo RP, Contino A, Sgarlata C, Spoto G, Tabbì G
Influence of the coordination geometry on the physicochemical properties of a copper(II) complex with a tailor-made calixarene-based ligand bearing dipyridyl pendants. An ESR, UV-Vis and CV study
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2004 Oct 21; (20): 3205-3211.

Pappalardo M, Milardi D, La Rosa C, Zannoni C, Rizzarelli E, Grasso D
A molecular dynamics study on the conformational stability of PrP 180-193 helix II prion fragment
Chem Phys Lett (ISSN: 0009-2614), 2004 Jun 1; 390(4-6): 511-516.

Cucinotta V, Giuffrida A, La Mendola D, Maccarrone G, Puglisi A, Rizzarelli E, Vecchio G
3-Amino Derivative Of Beta-Cyclodextrin: Thermodynamics Of Copper (ii) Complexes And Exploitation Of Its Enantioselectivity In The Separation Of Amino Acid Racemates By Ligand Exchange Capillary Electrophoresis
And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.

Mineo P, Vitalini D, La Mendola D, Rizzarelli E, Scamporrino E, Vecchio G
Coordination Features Of Difunctionalized Beta-Cyclodextrins With Carnosine: Esi-Ms And Spectroscopic Investigations On 6a, 6d-Di-(beta-Alanyl-L-Histidine)-6a, 6d-Dideoxy-Beta-Cyclodextrin And 6a, 6c-Di-(beta-Alanyl-L-Histidine)-6a, 6c-Dideoxy-Beta-Cyclodextrin And Their Copper (ii) Complexes
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2004 Feb; 98(2): 254-265.

Grasso D, Milardi D, La Rosa C, Rizzarelli E
The different role of Cu++ and Zn++ ions in affecting the interaction of prion peptide PrP106-126 with model membranes
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2004 Jan 21; 10(2): 246-247.

Brown DR, Guantieri V, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E
Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2004 Jan; 98(1): 133-143.

Barone V, Improta R, Rega N
Computation of protein pK's values by an integrated density functional theory/Polarizable Continuum Model approach
Theor Chem Acc (ISSN: 1432-881x), 2004; 111(2-6): 237-245.

Tizzano B, Marasco D, Benedetti E, De Capua A, Palladino P, Pedone C, Perretta G, Rossi F, Ragone R, Ruvo M
Conformational conversion of prion proteins: Role synthetic PRP 173-195 fibrillogenic peptide
Peptide Revolution, 2004; N/D: N/D-N/D.

Pappalardo G, Impellizzeri G, Campagna T
Copper(II) binding of prion protein's octarepeat model peptides
Inorg Chim Acta (ISSN: 0020-1693), 2004; 357(1): 185-194.

La Mendola D, Bonomo R, Maccarrone G, Pappalardo G, Rizzarelli E
A thermodynamic and spectroscopic study on the copper(II) complexes with hexarepeats fragments of the avian prion protein
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2003 Jul 15; 96(1): N/D-N/D.

Bonomo RP, Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Pappalardo G, Tabbì G, Rizzarelli E
Metal binding to prion protein
Metal-Ligand Interactions - Molecular Nano- Micro- And Macro-Systems In Complex Environments, 2003 Jan 01; 116: 21-39.

Grasso D, Milardi D, Guantieri V, La Rosa C, Rizzarelli E
Interaction of prion peptide PrP 180-193 with DPPC model membranes: A thermodynamic study
New J Chem (ISSN: 1144-0546), 2003; 27(2): 359-364.

Menziani MC, De Benedetti PG, Langella E, Barone V
Seeking for binding determinants of the prion protein to human plasminogen
Mol Phys (ISSN: 0026-8976), 2003; 101(17): 2763-2773.

Pappalardo G, Impellizzeri G, Bonomo RP, Campagna T, Grasso G, Saita MG
Copper(II) and nickel(II) binding modes in a histidine-containing model dodecapeptide
New J Chem (ISSN: 1144-0546), 2002; 26(5): 593-600.

Mineo P, Vitalini D, La Mendola D, Rizzarelli E, Scamporrino E, Vecchio G
Electrospray mass spectrometric studies of L-carnosine (β-alanyl-L-histidine) complexes with copper(II) or zinc ions in aqueous solution
Rapid Commun Mass Sp (ISSN: 0951-4198, 1097-0231electronic, 0951-4198linking), 2002; 16(7): 722-729.

Vecchio G, La Mendola D, Rizzarelli E, Sortino S
SOD-like activity of copper(II) complexes of beta-cyclodextrins functionalized with carnosine
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2001 Sep; 86(1): N/D-N/D.

Grasso D, Milardi D, La Rosa C, Rizzarelli E
DSC study of the interaction of the prion peptide PrP106-126 with artificial membranes
New J Chem (ISSN: 1144-0546), 2001; 25(12): 1543-1548.

Bonomo RP, Imperllizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
Copper(II) binding modes in the prion octapeptide PHGGGWGQ: A spectroscopic and voltammetric study
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2000 Nov 17; 6(22): 4195-4202.

Conato C, Contino A, Maccarrone G, Magrì A, Remelli M, Tabbì G
Copper(II) complexes with L-lysine and L-ornithine: Is the side-chain involved in the coordination? A thermodynamic and spectroscopic study
Thermochim Acta (ISSN: 0040-6031), 2000 Nov 13; 362(1-2): 13-23.

Tabbì G, Driessen WL, Reedijk J, Veldman N, Spek AL
The nickel(II) complex of a new multidentate ligand containing both imidazole and pyrazole moieties
Inorg Chim Acta (ISSN: 0020-1693), 1999; 288(2): 239-243.

Tabbì G, Nauser T, Koppenol WH, Reedijk J
A Pulse Radiolysis Study of an Imidazolato-Bridged Asymmetric Dicopper(II) Complex: A Structural and Functional Mimic of Superoxide Dismutase
Eur J Inorg Chem (ISSN: 1434-1948, 1099-0682e), 1998; (12): 1939-1943.

Bonomo RP, Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Tabbì G
Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity
Journal Of The Chemical Society Dalton Transactions (ISSN: 0300-9246), 1998; (22): 3851-3857.

Campagna T, Grasso G, Rizzarelli E, Vecchio G
L- and D-cysteine derivatives of β-cyclodextrin: Different molecular recognition properties of their copper(II) complexes for amino acids
Inorg Chim Acta (ISSN: 0020-1693), 1998; 275-276: 395-400.

Cucinotta V, Grasso D, Grasso G, Milardi D
Calorimetric evidences for Copper(II)-regulated chiral recognition between decanucleotide 5'd(CTGGATCCAG)2 and Ala-Trp dipeptides
Nucleosides Nucleotides (ISSN: 0732-8311), 1997; 16(10-11): 1847-1854.

Bonomo RP, Cucinotta V, D'Alessandro F, Impellizzeri G, Maccarrone G, Rizzarelli E, Vecchio G, Carima L, Corradini R, Sartor G, Marchelli R
Chiral recognition by the copper(ii) complex of 6-deoxy-6-n-(2 - methylaminopyridine)-β-cyclodextrin
Chirality (ISSN: 0899-0042), 1997; 9(4): 341-349.

Tabbì G, Driessen WL, Reedijk J, Bonomo RP, Veldman N, Spek AL
High Superoxide Dismutase Activity Of A Novel, Intramolecularly Imidazolato-Bridged Asymmetric Dicopper(ii) Species; Design, Synthesis, Structure And Magnetism Of Cu(ii) Complexes With A Mixed Pyrazole-Imidazole Donor Set
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1997; 36(6): 1168-1175.

Bonomo RP, Pedotti S, Vecchio G, Rizzarelli E
Molecular Recognition of Amino Acids by Copper(II) Complexes of 6A, 6X-Diamino-6A, 6 X-dideoxy-β-cyclodextrin (X = B, C, D)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Nov 6; 35(23): 6873-6877.

Bonomo RP, Di Blasio B, Maccarrone G, Pavone V, Pedone C, Rizzarelli E, Saviano M, Vecchio G
Crystal and Molecular Structure of the [6-Deoxy-6-[(2-(4-imidazolyl)ethyl)amino]cyclomaltoheptaose]copper(II) Ternary Complex with L-Tryptophanate. Role of Weak Forces in the Chiral Recognition Process Assisted by a Metallocyclodextrin
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Jul 17; 35(15): 4497-4504.

Veldman N, Spek AL, Tabbì G, Driessen WL, Reedijk J
A dinuclear nickel(II) compound: μ-{N, N, N′, N′-tetrakis[2-(3, 5-dimethyl-1-pyrazolyl)ethyl]-1, 2- ethylenediamine}-bis[aqua(nitrato-Ο, Ο + ′)nickel(II)] dinitrate dimethanol solvate
Acta Crystallogr Sect C Cryst Struct Commun (ISSN: 0108-2701), 1996; 52(11): 2698-2701.

Maccarrone G, Nardin G, Randaccio L, Tabbì G, Rosi M, Sgamellotti A, Rizzarelli E, Zangrando E
Structure Of Copper(ii) Complexes With L-Leucyl-D-Phenylalanine Or L-Leucyl-L-Phenylalanine And Lcao-Scf-Mo Calculations On The Stabilization Of Copper(ii) Complexes Due To D-π Interaction With Aromatic Ring
Dalton Trans, 1996; N/D: 3449-3453.

Bonomo RP, Marchelli R, Tabbì G
Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Nov 15; 60(3): 205-218.

Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.

Costanzo LL, De Guidi G, Giuffrida S, Sortino S, Condorelli G, Pappalardo G
Antioxidant effect of copper(II) on photosensitized lipid peroxidation
J Chem Res (ISSN: 0162-0134print, 0162-0134linking, 1873-3344), 1995 Feb; 57(2): 115-125.

Condorelli G, Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
INHIBITION OF PHOTOHEMOLYSIS BY COPPER(II) COMPLEXES WITH SOD-LIKE ACTIVITY
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Jun; 54(4): 257-265.

Bonomo RP, Conte E, Marchelli R, Santoro AM, Tabbì G
O2 - scavenger properties of copper(II) complexes with diamino-diamide-type ligands
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Feb 1; 53(2): 127-138.

Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
Determination of superoxide dismutase-like activity of copper(II) complexes. Relevance of the speciation for the correct interpretation of in vitro O2 - scavenger activity
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Jun; 50(4): 273-281.

Arena G, Bindoni M, Cardile V, Maccarrone G, Riello MC, Rizzarelli E, Sciuto S
Cytotoxic and cytostatic activity of copper(II) complexes. Importance of the speciation for the correct interpretation of the in vitro biological results
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Apr 1; 50(1): 31-45.

Bonomo RP, Bonsignore F, Conte E, Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E
Thermodynamic and Spectroscopic Characterization, and in vitro O2- Scavenger Activity of Copper(II) Complexes with Glycyl-L-histidyl-glycyl-L-histidine
J Chem Soc (ISSN: 1364-5447), 1993; 8: 1295-1300.

Alberghina M, Lupo G, La Spina G, Mangiameli A, Gulisano M, Sciotto D, Rizzarelli E
Cytoprotective effect of copper(II) complexes against ethanol-induced damage to rat gastric mucosa
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1992 Mar; 45(4): 245-259.

Alberghina M, Brogna A, Mangiameli A, Marletta F, Rizzarelli E, Sammartano S
Copper(II) complexes of aminoacids: Gastric acid antisecretory activity in rats
Farmaco Ed Sci, 1982 Dec; 37(12): 805-814.

Valora G, Bonomo RP, Tabbì G
An EPR and voltammetric study of simple and mixed copper(II) complexes with L- or D-glutamate and L-arginate in aqueous solution
Inorganica Chimica Acta, 2016 Lug 19; 453(2016): 62-68.