Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease
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Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease (181 views)

Acampa W, Assante R, Mannarino T, Zampella E, D'Antonio A, Buongiorno P, Gaudieri V, Nappi C, Giordano A, Mainolfi CG, Petretta M, Cuocolo A

Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1705-1712.

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Paper type: Journal Article,

Impact factor: 5.036, 5-year impact factor: 4.665

Url: Not available.

Keywords: Czt Camera , Dynamic Spect , Myocardial Blood Flow , Myocardial Perfusion Reserve,

Affiliations:
*** IBB - CNR ***

Department of Advanced Biomedical Sciences, University Federico II, Naples, Italy.
Institute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Department of Translational Medical Sciences, University Federico II, Naples, Italy.


References:
Not available.
Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease

BACKGROUND: We measured myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) by a dynamic low-dose CZT-SPECT protocol in patients with suspected or known coronary artery disease (CAD) and investigated the capability of dynamic data in predicting obstructive CAD. A total of 173 patients with suspected or known CAD underwent dynamic CZT-SPECT after the injection of 155 MBq and 370 MBq of (99m)Tc-sestamibi for rest and stress imaging, respectively. Standard rest and stress imaging were performed at the end of each dynamic scan. A total perfusion defect (TPD) < 5% were considered normal. Obstructive CAD was defined as ≥ 70% stenosis at coronary angiography. RESULTS: Global MPR was lower (p < 0.05) in patients with abnormal compared with those with normal MPI (2.40 ± 0.7 vs. 2.70 ± 0.8). A weak, albeit significant correlation between TPD and MPR (r = - 0.179, p < 0.05) was found. In 91 patients with available angiographic data, hyperemic MBF (2.59 ± 1.2 vs. 3.24 ± 1.1 ml/min/g) and MPR (1.96 ± 0.7 vs. 2.74 ± 0.9) were lower (both p < 0.05) in patients with obstructive CAD (n = 21) compared with those without (n = 70). At univariable analysis, TPD, hyperemic MBF, and MPR were significant predictors of obstructive CAD, whereas only MPR was independent predictor at multivariable analysis (p < 0.05). At per vessels analysis, regional hyperemic MBF (2.59 ± 1.2 vs. 3.24 ± 1.1 ml/min/g) and regional MPR (1.96 ± 0.7 vs. 2.74 ± 0.9) were lower in the 31 vessels with obstructive CAD compared with 242 vessels without (both p < 0.05). CONCLUSIONS: In patients with suspected or known CAD, MPR assessed by low-dose dynamic CZT-SPECT showed a good correlation with myocardial perfusion imaging findings and it could be useful to predict obstructive CAD.
Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease

▼    Noninvasive techniques for coronary flow reserve assessment
Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease

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Zampella E, Assante R, Gaudieri V, Nappi C, Acampa W, Cuocolo A
* Myocardial perfusion reserve by using CZT: It's a long way to the top if you wanna standardize (240 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2021 Jun; 28(3): 885-887.
Impact Factor: 2.811
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Mannarino T, Gaudieri V, Acampa W
* Vasodilators and myocardial blood flow by CZT cameras: Make us see further (102 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2020 Nov 17; N/D: N/D-N/D.
Impact Factor: 3.847
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Zampella E, Acampa W, Assante R, Gaudieri V, Nappi C, Mannarino T, Mainolfi CG, Arumugam P, Petretta M, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in predicting lesion-related outcome (171 views)
Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1698-1704.
Impact Factor: 5.036
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Nappi C, Ponsiglione A, Acampa W, Gaudieri V, Zampella E, Assante R, Cuocolo R, Mannarino T, Dell'Aversana S, Petretta M, Imbriaco M, Cuocolo A
* Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging (262 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412), 2019 Jul 13; 20(12): 1379-1387.
Impact Factor: 5.26
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Gaudieri V, Acampa W, Rozza F, Nappi C, Zampella E, Assante R, Mannarino T, Mainolfi C, Petretta M, Verberne HJ, Arumugam P, Cuocolo A
* Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis (246 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412electronic), 2019 Feb 14; N/D: N/D-N/D.
Impact Factor: 3.669
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Assante R, Zampella E, Arumugam P, Acampa W, Imbriaco M, Tout D, Petretta M, Tonge C, Cuocolo A
* Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease (549 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017; 24(2): 494-501.
Impact Factor: 4.011
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Petretta M, Storto G, Pellegrino T, Bonaduce D, Cuocolo A
* Quantitative Assessment of Myocardial Blood Flow with SPECT (568 views)
Prog Cardiovasc Dis (ISSN: 0033-0620), 2015 Jan 3; 57(6): 607-614.
Impact Factor: 4.635
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Cuocolo A, Cittanti C, Acampa W, Larobina M, Petretta M
* Current and Future Status of Blood Flow Tracers (370 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2011; 4(3): 227-236.
Impact Factor: 0
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Lucignani G, Cuocolo A
Advances in quantitative assessment of myocardial blood flow and coronary reserve (282 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Oct; 36(10): 1687-1692.
Impact Factor: 4.531
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (806 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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10 Records (9 excluding Abstracts).
Total impact factor: 36.242 (31.607 excluding Abstracts).
Total 5 year impact factor: 31.654 (27.766 excluding Abstracts).

Last modified by Gennaro Angrisano on Wednesday 13 January 2021, 14:40:27
181 views. Last view on Friday 11 October 2024, 11:00:47