Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients (1471 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992, 1935-5548electronic), 2012 Jul; 35(7): 1429-1435.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Randomized Controlled Trial, Research Support, Non-U. S. Gov'T,
Impact factor: 7.735, 5-year impact factor: 7.555
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84862885081&partnerID=40&md5=fe7808f7fdab090d4d2f442a45206d3a
Keywords: Metformin, Monounsaturated Fatty Acid, Adult, Aerobic Exercise, Aged, Article, Blood Glucose Monitoring, Body Weight, Caloric Intake, Carbohydrate Diet, Clinical Article, Controlled Study, Diet Therapy, Fat Content, Fat Intake, Fatty Liver, Female, Glycemic Index, High Fiber Diet, Human, Lipid Diet, Non Insulin Dependent Diabetes Mellitus, Parallel Design, Physical Activity, Qualitative Analysis, Randomized Controlled Trial, Reference Value, Risk Reduction, Treatment Duration, Treatment Response, Weight Reduction, Type 2, Middle Aged, Type 2 Blood Diet Therapy, Fats Analysis, Monounsaturated Administration, Dosage, Fatty Liver Prevention, Liver Metabolism, Metformin Therapeutic Use,
Affiliations:
*** IBB - CNR ***
Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Biostructure and Bioimaging Institute, National Research Council, Naples, Italy
Department of Biomorphological and Functional Science, Federico II University, Naples, Italy
References:
Not available.
Diabetes Care (ISSN: 1935-5548, 0149-5992, 1935-5548electronic), 2012 Jul; 35(7): 1429-1435.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Randomized Controlled Trial, Research Support, Non-U. S. Gov'T,
Impact factor: 7.735, 5-year impact factor: 7.555
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84862885081&partnerID=40&md5=fe7808f7fdab090d4d2f442a45206d3a
Keywords: Metformin, Monounsaturated Fatty Acid, Adult, Aerobic Exercise, Aged, Article, Blood Glucose Monitoring, Body Weight, Caloric Intake, Carbohydrate Diet, Clinical Article, Controlled Study, Diet Therapy, Fat Content, Fat Intake, Fatty Liver, Female, Glycemic Index, High Fiber Diet, Human, Lipid Diet, Non Insulin Dependent Diabetes Mellitus, Parallel Design, Physical Activity, Qualitative Analysis, Randomized Controlled Trial, Reference Value, Risk Reduction, Treatment Duration, Treatment Response, Weight Reduction, Type 2, Middle Aged, Type 2 Blood Diet Therapy, Fats Analysis, Monounsaturated Administration, Dosage, Fatty Liver Prevention, Liver Metabolism, Metformin Therapeutic Use,
Affiliations:
*** IBB - CNR ***
Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Biostructure and Bioimaging Institute, National Research Council, Naples, Italy
Department of Biomorphological and Functional Science, Federico II University, Naples, Italy
References:
Not available.
Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients
OBJECTIVE - To evaluate the effects of qualitative dietary changes and the interaction with aerobic exercise training on liver fat content independent of weight loss in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - With use of a factorial 2 x 2 randomized parallel-group design, 37 men and 8 women, aged 35-70 years, with type 2 diabetes in satisfactory blood glucose control on diet or diet plusmetformin treatmentwere assigned to one of the following groups for an 8-week period: 1) high-carbohydrate/high-fiber/low-glycemic index diet (CHO/fiber group), 2) high-MUFA diet (MUFA group), 3) high-carbohydrate/high- fiber/low- glycemic index diet plus physical activity program (CHO/fiber+Ex group), and 4) high-MUFA diet plus physical activity program (MUFA+Ex group). Before and after intervention, hepatic fat content was measured by 1H NMR. RESULTS - Dietary compliance was optimal and body weight remained stable in all groups. Liver fat content decreased more in MUFA (-29%) and MUFA+Ex (-25%) groups than in CHO/fiber (-4%) and CHO/fiber+Ex groups (-6%). Two-way repeated-measures ANOVA, including baseline values as covariate, showed a significant effect on liver fat content for diet (P = 0.006), with no effects for exercise training (P = 0.789) or diet-exercise interaction (P = 0.712). CONCLUSIONS - An isocaloric diet enriched in MUFA compared with a diet higher in carbohydrate and fiber was associated with a clinically relevant reduction of hepatic fat content in type 2 diabetic patients independent of an aerobic training program and should be considered for the nutritional management of hepatic steatosis in people with type 2 diabetes. © 2012 by the American Diabetes Association.
OBJECTIVE - To evaluate the effects of qualitative dietary changes and the interaction with aerobic exercise training on liver fat content independent of weight loss in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS - With use of a factorial 2 x 2 randomized parallel-group design, 37 men and 8 women, aged 35-70 years, with type 2 diabetes in satisfactory blood glucose control on diet or diet plusmetformin treatmentwere assigned to one of the following groups for an 8-week period: 1) high-carbohydrate/high-fiber/low-glycemic index diet (CHO/fiber group), 2) high-MUFA diet (MUFA group), 3) high-carbohydrate/high- fiber/low- glycemic index diet plus physical activity program (CHO/fiber+Ex group), and 4) high-MUFA diet plus physical activity program (MUFA+Ex group). Before and after intervention, hepatic fat content was measured by 1H NMR. RESULTS - Dietary compliance was optimal and body weight remained stable in all groups. Liver fat content decreased more in MUFA (-29%) and MUFA+Ex (-25%) groups than in CHO/fiber (-4%) and CHO/fiber+Ex groups (-6%). Two-way repeated-measures ANOVA, including baseline values as covariate, showed a significant effect on liver fat content for diet (P = 0.006), with no effects for exercise training (P = 0.789) or diet-exercise interaction (P = 0.712). CONCLUSIONS - An isocaloric diet enriched in MUFA compared with a diet higher in carbohydrate and fiber was associated with a clinically relevant reduction of hepatic fat content in type 2 diabetic patients independent of an aerobic training program and should be considered for the nutritional management of hepatic steatosis in people with type 2 diabetes. © 2012 by the American Diabetes Association.
Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients
| ▼ Animal Care, interventional procedures, anesthesia and analgesia of murine models in preclinical imaging |
Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients
Other filter: ([btitle,keywords] "Monounsaturated Fatt ...
Bozzetto L, Polito R, Nigro E, Prinster A, Della Pepa G, Costabile G, Vetrani C, Vitale M, Daniele A, Rivellese AA, Annuzzi G
* Dietary influence on adiponectin in patients with type 2 diabetes (338 views)
Eur J Clin Invest (ISSN: 0014-2972linking, 1365-2362), 2021 Aug; 51(8): e13548-N/D.
Impact Factor: 3.086
View Export to BibTeX Export to EndNote
Clemente G, Giorgini M, Mancini M, Gallo M, Amd-associazione Medici Diabetologi ‘diabetes Cancer’ worki
* Diabetologists and Oncologists attitudes towards treating diabetes in the oncologic patient: Insights from an exploratory survey (339 views)
Diabetes Res Clin Pract (ISSN: 0168-8227linking), 2018 Sep; 143: 420-427.
Impact Factor: 3.639
View Export to BibTeX Export to EndNote
Bozzetto L, Costabile G, Luongo D, Naviglio D, Cicala V, Piantadosi C, Patti L, Cipriano P, Annuzzi G, Rivellese AA
* Reduction in liver fat by dietary MUFA in type 2 diabetes is helped by enhanced hepatic fat oxidation (324 views)
Diabetologia (ISSN: 0012-186x), 2016 Dec; 59(12): 2697-2701.
Impact Factor: 6.08
View Export to BibTeX Export to EndNote
Gargiulo S, Anzilotti S, Coda AR, Gramanzini M, Greco A, Panico M, Vinciguerra A, Zannetti A, Vicidomini C, Dolle F, Pignataro G, Quarantelli M, Annunziato L, Brunetti A, Salvatore M, Pappata S
* Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT (1013 views) (PDF 323 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2016 Jan 27; 43(7): 1348-1359.
Impact Factor: 7.277
View Export to BibTeX Export to EndNote
Gargiulo S, Gramanzini M, Megna R, Greco A, Albanese S, Manfredi C, Brunetti A
* Evaluation of growth patterns and body composition in C57Bl/6J mice using dual energy X-ray absorptiometry (750 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2014 Jul; 2014: 253067-253067.
Impact Factor: 1.579
View Export to BibTeX Export to EndNote
Gramanzini M, Di Girolamo N, Gargiulo S, Greco A, Cocchia N, Delogu M, Rosapane I, Liuzzi R, Selleri P, Brunetti A
* Assessment Of Dual-Energy X-Ray Absorptiometry For Use In Evaluating The Effects Of Dietary And Environmental Management On Hermann'S Tortoises (testudo Hermanni) (828 views)
Am J Vet Res (ISSN: 0002-9645, 0002-2964), 2013 Jun; 74(6): 918-924.
Impact Factor: 1.214
View Export to BibTeX Export to EndNote
Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (613 views)
J Clin Endocrinol Metab (ISSN: 1945-7197, 0021-972x, 0021-972xlinking), 2013 Mar; 98(3): 1214-1218.
Impact Factor: 6.31
View Export to BibTeX Export to EndNote
Giacco R, Della Pepa G, Luongo D, Riccardi G
* Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials (802 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2011 Dec; 21(12): 901-908.
Impact Factor: 3.731
View Export to BibTeX Export to EndNote
Pedone C, Napoli N, Pozzilli P, Rossi FF, Lauretani F, Bandinelli S, Ferrucci L, Antonelli-Incalzi R
* Dietary pattern and bone density changes in elderly women: a longitudinal study (662 views)
J Am Coll Nutr (ISSN: 1541-1087, 0731-5724), 2011 Apr; 30(2): 149-154.
Impact Factor: 2.29
View Export to BibTeX Export to EndNote
Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (1203 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
View Export to BibTeX Export to EndNote
Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (1536 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
View Export to BibTeX Export to EndNote
Cittadini A, Monti MG, Iaccarino G, Di Rella F, Tsichlis PN, Di Gianni A, Strömer H, Sorriento D, Peschle C, Trimarco B, Saccà L, Condorelli G
* Adenoviral gene transfer of Akt enhances myocardial contractility and intracellular calcium handling (1964 views)
Gene Ther (ISSN: 0969-7128, 0969-7128linking), 2006; 13(1): 8-19.
Impact Factor: 4.782
View Export to BibTeX Export to EndNote
Leosco D, Iaccarino G, Cipolletta E, De Santis D, Pisani E, Trimarco V, Ferrara N, Abete P, Sorriento D, Rengo F, Trimarco B
* Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries (435 views)
Am J Physiol Heart Circ Physiol American Journal Of Physiology Heart And Circulatory Physiology (ISSN: 0363-6135), 2003; 285(154-1): H369-H369.
Impact Factor: 3.658
View Export to BibTeX Export to EndNote
Ferrara LA, Marotta T, Mainenti G, Borrelli R, Mancini M, Soro S
Resting blood pressure and cardiovascular response to sympathetic stimulation in adolescents (539 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic), 1992 Sep; 36(2): 197-201.
Impact Factor: 0.61
View Export to BibTeX Export to EndNote
Ferrara LA, Mancini M, De Simone GD, Turco S, Iovine C, Marotta T, Mainenti G, Mancini M
Responses of serum insulin and blood pressure to cold and handgrip in obese patients (461 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic), 1991 Sep; 32(3): 353-359.
Impact Factor: 0.61
View Export to BibTeX Export to EndNote
Ferrara LA, Soro S, Mainenti G, Mancini M, Pisanti N, Borrelli R, Moscato TS
Body weight and cardiovascular response to sympathetic stimulation in childhood (984 views)
Int J Obes (ISSN: 0307-0565, 0307-0565linking), 1989; 13(3): 271-277.
Impact Factor: 2.476
View Export to BibTeX Export to EndNote
Alberghina M, Brogna A, Mangiameli A, Marletta F, Rizzarelli E, Sammartano S
Copper(II) complexes of aminoacids: Gastric acid antisecretory activity in rats (2159 views)
Farmaco Ed Sci, 1982 Dec; 37(12): 805-814.
Impact Factor: 0
View Export to BibTeX Export to EndNote
* Dietary influence on adiponectin in patients with type 2 diabetes (338 views)
Eur J Clin Invest (ISSN: 0014-2972linking, 1365-2362), 2021 Aug; 51(8): e13548-N/D.
Impact Factor: 3.086
View Export to BibTeX Export to EndNote
Clemente G, Giorgini M, Mancini M, Gallo M, Amd-associazione Medici Diabetologi ‘diabetes Cancer’ worki
* Diabetologists and Oncologists attitudes towards treating diabetes in the oncologic patient: Insights from an exploratory survey (339 views)
Diabetes Res Clin Pract (ISSN: 0168-8227linking), 2018 Sep; 143: 420-427.
Impact Factor: 3.639
View Export to BibTeX Export to EndNote
Bozzetto L, Costabile G, Luongo D, Naviglio D, Cicala V, Piantadosi C, Patti L, Cipriano P, Annuzzi G, Rivellese AA
* Reduction in liver fat by dietary MUFA in type 2 diabetes is helped by enhanced hepatic fat oxidation (324 views)
Diabetologia (ISSN: 0012-186x), 2016 Dec; 59(12): 2697-2701.
Impact Factor: 6.08
View Export to BibTeX Export to EndNote
Gargiulo S, Anzilotti S, Coda AR, Gramanzini M, Greco A, Panico M, Vinciguerra A, Zannetti A, Vicidomini C, Dolle F, Pignataro G, Quarantelli M, Annunziato L, Brunetti A, Salvatore M, Pappata S
* Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with (18)F-DPA-714 and micro-PET/CT (1013 views) (PDF 323 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2016 Jan 27; 43(7): 1348-1359.
Impact Factor: 7.277
View Export to BibTeX Export to EndNote
Gargiulo S, Gramanzini M, Megna R, Greco A, Albanese S, Manfredi C, Brunetti A
* Evaluation of growth patterns and body composition in C57Bl/6J mice using dual energy X-ray absorptiometry (750 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2014 Jul; 2014: 253067-253067.
Impact Factor: 1.579
View Export to BibTeX Export to EndNote
Gramanzini M, Di Girolamo N, Gargiulo S, Greco A, Cocchia N, Delogu M, Rosapane I, Liuzzi R, Selleri P, Brunetti A
* Assessment Of Dual-Energy X-Ray Absorptiometry For Use In Evaluating The Effects Of Dietary And Environmental Management On Hermann'S Tortoises (testudo Hermanni) (828 views)
Am J Vet Res (ISSN: 0002-9645, 0002-2964), 2013 Jun; 74(6): 918-924.
Impact Factor: 1.214
View Export to BibTeX Export to EndNote
Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (613 views)
J Clin Endocrinol Metab (ISSN: 1945-7197, 0021-972x, 0021-972xlinking), 2013 Mar; 98(3): 1214-1218.
Impact Factor: 6.31
View Export to BibTeX Export to EndNote
Giacco R, Della Pepa G, Luongo D, Riccardi G
* Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials (802 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2011 Dec; 21(12): 901-908.
Impact Factor: 3.731
View Export to BibTeX Export to EndNote
Pedone C, Napoli N, Pozzilli P, Rossi FF, Lauretani F, Bandinelli S, Ferrucci L, Antonelli-Incalzi R
* Dietary pattern and bone density changes in elderly women: a longitudinal study (662 views)
J Am Coll Nutr (ISSN: 1541-1087, 0731-5724), 2011 Apr; 30(2): 149-154.
Impact Factor: 2.29
View Export to BibTeX Export to EndNote
Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (1203 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
View Export to BibTeX Export to EndNote
Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (1536 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
View Export to BibTeX Export to EndNote
Cittadini A, Monti MG, Iaccarino G, Di Rella F, Tsichlis PN, Di Gianni A, Strömer H, Sorriento D, Peschle C, Trimarco B, Saccà L, Condorelli G
* Adenoviral gene transfer of Akt enhances myocardial contractility and intracellular calcium handling (1964 views)
Gene Ther (ISSN: 0969-7128, 0969-7128linking), 2006; 13(1): 8-19.
Impact Factor: 4.782
View Export to BibTeX Export to EndNote
Leosco D, Iaccarino G, Cipolletta E, De Santis D, Pisani E, Trimarco V, Ferrara N, Abete P, Sorriento D, Rengo F, Trimarco B
* Exercise restores β-adrenergic vasorelaxation in aged rat carotid arteries (435 views)
Am J Physiol Heart Circ Physiol American Journal Of Physiology Heart And Circulatory Physiology (ISSN: 0363-6135), 2003; 285(154-1): H369-H369.
Impact Factor: 3.658
View Export to BibTeX Export to EndNote
Ferrara LA, Marotta T, Mainenti G, Borrelli R, Mancini M, Soro S
Resting blood pressure and cardiovascular response to sympathetic stimulation in adolescents (539 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic), 1992 Sep; 36(2): 197-201.
Impact Factor: 0.61
View Export to BibTeX Export to EndNote
Ferrara LA, Mancini M, De Simone GD, Turco S, Iovine C, Marotta T, Mainenti G, Mancini M
Responses of serum insulin and blood pressure to cold and handgrip in obese patients (461 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic), 1991 Sep; 32(3): 353-359.
Impact Factor: 0.61
View Export to BibTeX Export to EndNote
Ferrara LA, Soro S, Mainenti G, Mancini M, Pisanti N, Borrelli R, Moscato TS
Body weight and cardiovascular response to sympathetic stimulation in childhood (984 views)
Int J Obes (ISSN: 0307-0565, 0307-0565linking), 1989; 13(3): 271-277.
Impact Factor: 2.476
View Export to BibTeX Export to EndNote
Alberghina M, Brogna A, Mangiameli A, Marletta F, Rizzarelli E, Sammartano S
Copper(II) complexes of aminoacids: Gastric acid antisecretory activity in rats (2159 views)
Farmaco Ed Sci, 1982 Dec; 37(12): 805-814.
Impact Factor: 0
View Export to BibTeX Export to EndNote
17 Records (17 excluding Abstracts).
Total impact factor: 53.04 (53.04 excluding Abstracts).
Total 5 year impact factor: 58.189 (58.189 excluding Abstracts).
Total impact factor: 53.04 (53.04 excluding Abstracts).
Total 5 year impact factor: 58.189 (58.189 excluding Abstracts).
1471 views. Last view on Sunday 13 October 2024, 5:51:20
ibb.cnr.it
