Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems (64 views)
Journal Of Nanostructure In Chemistry, 2023 Feb; N/D: N/D-N/D.
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Impact factor: 10.1, 5-year impact factor: 9.4
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Affiliations:
*** IBB - CNR ***
The design, synthesis and characterization of a novel nucleoamino acid derivative based on an l-tryptophanamide func-tionalised with a thymine nucleobase (named TrpT) is here described. The novel construct’s tendency to self-assemble into supramolecular networks in aqueous solution was demonstrated by dynamic light scattering (DLS), circular dichroism (CD), fluorescence and UV spectroscopic measurements. TrpT nanoaggregates showed good stability (up to 5 h) at 140 μM and proved to comprise species of mean hydrodynamic diameter 330 nm and a homogeneous size distribution; scanning electron microscopy (SEM) analysis further revealed these to be spherical-shaped assemblies. The ability of TrpT nanoaggregates to bind curcumin, selected as a model anticancer drug, was also evaluated and its release was monitored over time by confocal microscopy. Molecular docking studies were performed on both TrpT self-assembly and curcumin-loaded nanoaggregates suggesting that the phytomolecule can be accommodated in the interior of the supramolecular network via hydrophobic (π−π and π-alkyl) interactions; the formation of TrpT-curcumin adducts may improve the polarity of the highly-hydrophobic curcumin with a resulting logP closer to the optimal values expected for a good drug bioavailability, as estimated by the ADMETlab software. Finally, the high stability of TrpT nanoassembly in human serum, and the absence of significant toxic effects on human model cells in a cell viability assay, were also demonstrated. Despite its thymine-based scaffold, TrpT was shown not to bind adenine-bearing nucleic acids, suggesting that this interaction is hindered by its intrinsic propensity to self-assemble in preference to forming A-T base pairings. Instead, TrpT was able to interact with a serum protein such as bovine serum albumin (BSA), known to improve the bloodstream transportation and bioavailability of its cargo. Collectively, our findings support the potential use of TrpT for the development of new drug delivery systems.
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Not available.
Journal Of Nanostructure In Chemistry, 2023 Feb; N/D: N/D-N/D.
Export to BibTeX Export to EndNote
Paper type: Not available.
Impact factor: 10.1, 5-year impact factor: 9.4
Url: Not available.
Keywords: Not available.
Affiliations:
*** IBB - CNR ***
The design, synthesis and characterization of a novel nucleoamino acid derivative based on an l-tryptophanamide func-tionalised with a thymine nucleobase (named TrpT) is here described. The novel construct’s tendency to self-assemble into supramolecular networks in aqueous solution was demonstrated by dynamic light scattering (DLS), circular dichroism (CD), fluorescence and UV spectroscopic measurements. TrpT nanoaggregates showed good stability (up to 5 h) at 140 μM and proved to comprise species of mean hydrodynamic diameter 330 nm and a homogeneous size distribution; scanning electron microscopy (SEM) analysis further revealed these to be spherical-shaped assemblies. The ability of TrpT nanoaggregates to bind curcumin, selected as a model anticancer drug, was also evaluated and its release was monitored over time by confocal microscopy. Molecular docking studies were performed on both TrpT self-assembly and curcumin-loaded nanoaggregates suggesting that the phytomolecule can be accommodated in the interior of the supramolecular network via hydrophobic (π−π and π-alkyl) interactions; the formation of TrpT-curcumin adducts may improve the polarity of the highly-hydrophobic curcumin with a resulting logP closer to the optimal values expected for a good drug bioavailability, as estimated by the ADMETlab software. Finally, the high stability of TrpT nanoassembly in human serum, and the absence of significant toxic effects on human model cells in a cell viability assay, were also demonstrated. Despite its thymine-based scaffold, TrpT was shown not to bind adenine-bearing nucleic acids, suggesting that this interaction is hindered by its intrinsic propensity to self-assemble in preference to forming A-T base pairings. Instead, TrpT was able to interact with a serum protein such as bovine serum albumin (BSA), known to improve the bloodstream transportation and bioavailability of its cargo. Collectively, our findings support the potential use of TrpT for the development of new drug delivery systems.
References:
Not available.
Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems
Not available.
Not available.
Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems
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Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems
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* The renaissance era of peptides in drug discovery at the 14th Naples workshop on bioactive peptides (562 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 321-322.
Impact Factor: 1.951
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Gargiulo S, Gramanzini M, Megna R, Greco A, Albanese S, Manfredi C, Brunetti A
* Evaluation of growth patterns and body composition in C57Bl/6J mice using dual energy X-ray absorptiometry (708 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2014 Jul; 2014: 253067-253067.
Impact Factor: 1.579
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Calce E, Mignogna E, Bugatti V, Galdiero M, Vittoria V, De Luca S
* Pectin functionalized with natural fatty acids as antimicrobial agent (521 views)
Int J Biol Macromol (ISSN: 0141-8130, 0141-8130linking, 1879-0003electronic), 2014 Jul; 68: 28-32.
Impact Factor: 2.858
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Bilo L, Peluso S, Antenora A, De Rosa A, Auletta G, Pappata S, De Michele G
* Parkinsonism may be part of the symptom complex of DOOR syndrome (354 views)
Parkinsonism Relat D (ISSN: 1353-8020, 1873-5126, 1353-8020print), 2014 Apr; 20(4): 463-465.
Impact Factor: 3.972
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Troise AD, Dathan NA, Fiore A, Roviello G, Di Fiore A, Caira S, Cuollo M, De Simone G, Fogliano V, Monti SM
* Faox enzymes inhibited Maillard reaction development during storage both in protein glucose model system and low lactose UHT milk (297 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014 Feb; 46(2): 279-288.
Impact Factor: 3.293
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Orlandini S, Pasquini B, Gotti R, Giuffrida A, Paternostro F, Furlanetto S
* Analytical quality by design in the development of a cyclodextrin-modified capillary electrophoresis method for the assay of metformin and its related substances (317 views)
Electrophoresis (ISSN: 0173-0835), 2014; 35(17): 2538-2545.
Impact Factor: 3.028
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Greco A, Ragucci M, Coda ARD, Rosa A, Gargiulo S, Liuzzi R, Gramanzini M, Albanese S, Pappata S, Mancini M, Brunetti A, Salvatore M
* Correction: High frequency ultrasound for in vivo pregnancy diagnosis and staging of placental and fetal development in mice (PLoS ONE) (354 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014; 9(1): N/D-N/D.
Impact Factor: 3.234
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De Simone G, Pizika G, Monti SM, Di Fiore A, Ivanova J, Vozny I, Trapencieris P, Zalubovskis R, Supuran CT, Alterio V
* Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors (376 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2014; 2014: 523210-523210.
Impact Factor: 1.579
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Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S
* Structure-Activity Relations of Myxinidin, an Antibacterial Peptide Derived from the Epidermal Mucus of Hagfish (926 views)
Antimicrob Agents Ch (ISSN: 0066-4804, 1098-6596), 2013 Nov; 57(11): 5665-5673.
Impact Factor: 4.451
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Greco A, Ragucci M, Coda ARD, Rosa A, Gargiulo S, Liuzzi R, Gramanzini M, Albanese S, Pappata S, Mancini M, Brunetti A, Salvatore M
* High frequency ultrasound for in vivo pregnancy diagnosis and staging of placental and fetal development in mice (491 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Oct 14; 8(10): e77205-e77205.
Impact Factor: 3.534
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Portella L, Vitale R, De Luca S, D'Alterio C, Ieranò C, Napolitano M, Riccio A, Polimeno MN, Monfregola L, Barbieri A, Luciano A, Ciarmiello A, Arra C, Castello G, Amodeo P, Scala S
* Preclinical Development of a Novel Class of CXCR4 Antagonist Impairing Solid Tumors Growth and Metastases (579 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Sep 13; 8(9): N/D-N/D.
Impact Factor: 3.534
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Lombardo B, Rocco T, Esposito MT, Cantilena B, Gargiulo S, Greco A, Montanaro D, Brunetti A, Pastore L
* Thymidine Kinase-Mediated Shut Down of Bone Morphogenetic Protein-4 Expression Allows Regulated Bone Production (569 views)
Current Gene Therapy (ISSN: 1566-5232, 1875-5631), 2013 Jun 1; 13(3): 202-210.
Impact Factor: 4.906
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Accardo A, Tesauro D, Morelli G
* Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (539 views)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Impact Factor: 1.554
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D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (440 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
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Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Development of multivariate NTCP models for radiation-induced hypothyroidism: A comparative analysis (535 views) (PDF 252 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2012 Dec 27; 7(1): 224-224.
Impact Factor: 2.107
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Berisio R
* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (668 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 697-698.
Impact Factor: 2.326
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Balbi L, Greco D, Innocenti S, Sirignano C, Palma G, Soscia E, Alfano B, Salvatore M
* T2 & T2ρ Maps: Sequence Development And Clinical Impact On Joint Study (447 views) (PDF 250 views)
Ecr 2012, 2012 Oct; N/D: C-2444.
Impact Factor: 0
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Soscia E, Sirignano C, Catalano O, Atteno M, Costa L, Caso F, Peluso R, Bruner V, Aquino MM, Del Puente A, Salvatore M, Scarpa R
* New developments in magnetic resonance imaging of the nail unit (490 views)
Journal Of Rheumatology (ISSN: 0315-162x), 2012 Jul; 39(SUPPL.89): 49-53.
Impact Factor: 3.258
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Di Maro A, Berisio R, Ruggiero A, Tamburino R, Severino V, Zacchia E, Parente A
* Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica (475 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 May 11; 421(3): 514-520.
Impact Factor: 2.406
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Paladini D, Quarantelli M, Pastore G, Sorrentino M, Sglavo G, Nappi C
* Abnormal or delayed development of the posterior membranous area of the brain: Anatomy, ultrasound diagnosis, natural history and outcome of Blake's pouch cyst in the fetus (644 views)
Ultrasound Obst Gyn (ISSN: 0960-7692, 1469-0705), 2012 Mar; 39(3): 279-287.
Impact Factor: 3.557
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Calafiore M, Copani A, Deng W
* DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres (701 views)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2012 Mar; 90(3): 559-567.
Impact Factor: 2.974
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Paladini D, Quarantelli M, Pastore G, Sorrentino M, Sglavo G, Nappi C
* Abnormal Or Delayed Development Of The Area Membranacea Posterior Of The Brain: The Blake'S Pouch Cyst. Anatomy, Ultrasound Diagnosis, Natural History And Outcome In The Fetus (429 views)
Ultrasound Obstet Gynecol, 2012; 39: 279-287.
Impact Factor: 4.368
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D'Ambrosio K, Smaine F-Z, Carta F, De Simone G, Winum J-Y, Supuran CT
* Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups (552 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2012; 55(15): 6776-6783.
Impact Factor: 5.614
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Di Fiore A, Maresca A, Supuran CT, De Simone G
* Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors (417 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2012; 48(70): 8838-8840.
Impact Factor: 6.378
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Greco A, Mancini M, Gargiulo S, Gramanzini M, Claudio PP, Brunetti A, Salvatore M
* Ultrasound biomicroscopy in small animal research: Applications in molecular and preclinical imaging (763 views)
J Biomed Biotechnol (ISSN: 1110-7243, 1110-7251), 2012; 2012: 519238-519238.
Impact Factor: 2.88
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Falanga A, Vitiello MT, Cantisani M, Tarallo R, Guarnieri D, Mignogna E, Netti P, Pedone C, Galdiero M, Galdiero S
* A peptide derived from herpes simplex virus type 1 glycoprotein H: membrane translocation and applications to the delivery of quantum dots (1365 views)
Nanomedicine (ISSN: 1549-9642, 1549-9634, 1549-9642electronic), 2011 Dec; 7(6): 925-934.
Impact Factor: 6.692
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Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
* A versatile strategy for signal amplification based on core/shell silica nanoparticles (596 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Nov 25; 17(48): 13429-13432.
Impact Factor: 5.925
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Durazzo M, Campion D, Fagoonee S, Pellicano R, Sonne JU, Erckenbrecht JF, Grassi M, Petraccia L, Mennuni G, Fontana M, Scarno A, Sabetta S, Fraioli A
* Changes, functional disorders, and diseases in the gastrointestinal tract of elderly (223 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking, 1432-1289electronic), 2011 Jul; 2655108(6): 659-668.
Impact Factor: 0.913
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Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (388 views) (PDF 238 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
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Soscia E, Palma G, Sirignano C, Iodice D, Innocenti S, Greco D, Alfano B, Salvatore M
* Relaxometric Maps: Sequence Development And Clinical Impact. Initial Observations (453 views) (PDF 200 views)
Ecr 2011, 2011 Mar; 10.1594/ecr2011/C-09: C-0998.
Impact Factor: 0
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Sirignano C, Soscia E, Iodice D, Innocenti S, Palma G, Greco D, Balbi L, Alfano B, Salvatore M
* T2 & T2ρ Maps: Sequence Development And Clinical Impact On Joint Study (1288 views) (PDF 238 views)
Ismrm March 2011, 2011 Mar; N/D: N/D-N/D.
Impact Factor: 0
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Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (961 views)
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2011 Jan 15; 433(2): 345-355.
Impact Factor: 4.897
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Monfregola L, Leone M, Vittoria V, Amodeo P, De Luca S
* Chemical modification of pectin: Environmental friendly process for new potential material development (354 views)
Polym Chem (ISSN: 1759-9954), 2011; 2(4): 800-804.
Impact Factor: 5.321
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Amorosi S, Vigliano I, Del Giudice E, Panico L, Maruotti GM, Fusco A, Quarantelli M, Ciccone C, Ursini MV, Martinelli P, Pignata C
* Brain alteration in a Nude/SCID fetus carrying FOXN1 homozygous mutation (615 views)
J Neurol Sci (ISSN: 0022-510x, 0022-510xlinking), 2010 Nov 15; 298(1-2): 121-123.
Impact Factor: 2.167
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Calvanese L, Marasco D, Doti N, Saporito A, D'Auria G, Paolillo L, Ruvo M, Falcigno L
* Structural Investigations on the Nodal-Cripto Binding: A Theoretical and Experimental Approach (653 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Nov; 93(11): 1011-1021.
Impact Factor: 2.572
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Avitabile C, Moggio L, D'Andrea LD, Pedone C, Romanelli A
* Development of an efficient and low-cost protocol for the manual PNA synthesis by Fmoc chemistry (634 views)
Tetrahedron Lett (ISSN: 0040-4039), 2010 Jul 21; 51(29): 3716-3718.
Impact Factor: 2.618
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (717 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Di Stasi R, Diana D, Capasso D, Palumbo R, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD
* VEGFR1(D2) in drug discovery: Expression and molecular characterization (600 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010; 94(6): 800-809.
Impact Factor: 2.572
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Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (581 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Impact Factor: 1.807
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Doti N, Marasco D, Sabatella M, Monti SM, Dathan N, Viparelli F, Cassese A, Miele C, Pedone C, Ruvo M
* An analysis of deletion mutants of the PLD1 D4 domain defines short regions within the PLD1 interacting with PED/PEA15: implications for the development of peptides-specific antagonist (480 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Zaccaro L, Del Gatto A, Saviano M, Langella E, Langlois C, Di Lello P, Baffreau J, Mas C, Legault P, Omichinski JG, Pedone C
* Development of new molecules that compete with p53 for Binding to TFIIH (435 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
* The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development (543 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2008; 15(24): 2420-2432.
Impact Factor: 4.823
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Russo M, Meomartino L, Greco A, Catone G, Cocchia N, Tortora G, Brunetti A
* Pregnancy detection in mice using ultrasound (504 views)
Vet Rec (ISSN: 0042-4900), 2007 Mar 31; 160(13): 446-447.
Impact Factor: 1.087
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Volpe P, Paladini D, Resta M, Stanziano A, Salvatore M, Quarantelli M, De Robertis V, Buonadonna AL, Caruso G, Gentile M
* Characteristics, associations and outcome of partial agenesis of the corpus callosum in the fetus (460 views)
Ultrasound Obst Gyn (ISSN: 0960-7692, 1469-0705), 2006 May; 27(5): 509-516.
Impact Factor: 2.288
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D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (954 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285, 1747-0277linking), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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Bernini E De Nuccio R, Brescia F, Minardo A, Zeni L, Sarro PM, Palumbo R, Scarf MR
* Development and characterization of an integrated silicon micro flow cytometer (415 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2006; 386(5): 1267-1272.
Impact Factor: 2.591
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Saviano M, Zaccaro L, Benedetti E, Pedone C, Del Gatto A, Feliciello A, Affaiatati A, Avvedimento EV
* Development of peptides able to modulate the interaction of AKAP121 with mitochondria (516 views)
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
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Le Provost JB, Bartres-faz D, Paillere-martinot ML, Artiges E, Pappata S, Recasens C, Perez-gomez M, Bernardo M, Baeza I, Bayle F, Martinot JL
* Paracingulate sulcus morphology in men with early-onset schizophrenia (373 views)
Br J Psychiatry (ISSN: 0007-1250), 2003 Mar; 182(MAR.): 228-232.
Impact Factor: 4.421
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Kozarski M, Ferrari G, Clemente F, Gorczynska K, De Lazzari C, Darowski M, Mimmo R, Tosti G, Guaragno M
* A hybrid mock circulatory system: development and testing of an electro-hydraulic impedance simulator (415 views)
Int J Artif Organs (ISSN: 0391-3988, 0391-3988print), 2003 Jan; 26(1): 53-63.
Impact Factor: 0.964
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Accardo A, Ricci F, Basso P, Lega M
* Development Approach And Testing Of An Unmanned Aerial Vehicle (278 views)
23rd International Council Of Aeronautical Sciences Toronto Canada, 2002; N/D: 13-13.
Impact Factor: 4.622
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Dathan N, Parlato R, Rosica A, De Felice M, Di Lauro R
* Distribution Of The Titf2/Foxe1 Gene Product Is Consistent With An Important Role In The Development Of Foregut Endoderm, Palate, And Hair (301 views)
Developmental Dynamics, 2002; 224: 450-456.
Impact Factor: 2.668
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (614 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Lombardi G, Colao A, Cuocolo A, Longobardi S, Di Somma C, Orio F, Merola B, Nicolai E, Salvatore M
Cardiological aspects of growth hormone and insulin-like growth factor- (1049 views)
J Pediatr Endocrinol Metab (ISSN: 0334-018x), 1997 Nov; 10(6): 553-560.
Impact Factor: 0.481
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Gomez Palacios LR, Bracamonte AG
Development of nano- and microdevices for the next generation of biotechnology, wearables and miniaturized instrumentation (56 views)
Rsc Adv (ISSN: 2046-2069electronic), N/D; 12 (20 ): 12806-12822.
Impact Factor: 3.84
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Cardiovascular risk factors and development of nomograms in an Italian cohort of patients with suspected coronary artery disease undergoing SPECT or PET stress myocardial perfusion imaging (38 views)
Frontiers In Nuclear Medicine, 2024 Feb 14; N/D: 1-9.
Impact Factor: 0
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Panella R, Petri A, Desai BN, Fagoonee S, Cotton CA, Nguyen PK, Lundin EM, Wagshal A, Wang DZ, Näär AM, Vlachos IS, Maratos-flier E, Altruda F, Kauppinen S, Paolo Pandolfi P
* MicroRNA-22 Is a Key Regulator of Lipid and Metabolic Homeostasis (45 views)
Int J Mol Sci (ISSN: 1422-0067linking), 2023 Aug 17; 24 (16 ): N/D-N/D.
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Sandomenico A, Ruggiero A, Iaccarino E, Oliver A, Squeglia F, Moreira M, Esposito L, Ruvo M, Berisio R
* Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation (115 views)
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Impact Factor: 6.21
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Romano M, Squeglia F, Kramarska E, Barra G, Choi HG, Kim HJ, Ruggiero A, Berisio R
* A Structural View at Vaccine Development against M. tuberculosis (71 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2023 Jan 14; 12(2): N/D-N/D.
Impact Factor: 7.7
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Verdoliva V, Saviano M, De Luca S
Correction: Zeolites as Acid/Basic Solid Catalysts: Recent Synthetic Developments(Catalysts, (2019), 9, (248), 10. 3390/catal9030248) (26 views)
Catalysts, 2023; 13 (4 ): N/D-N/D.
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Squeglia F, Romano M, Esposito L, Barra G, Campiglia P, Sala M, Scala MC, Ruggiero A, Berisio R
* Structure-Based Development of SARS-CoV-2 Spike Interactors (72 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic), 2022 May 17; 23(10): N/D-N/D.
Impact Factor: 6.21
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Mazzoni LN, Bock M, Levesque IR, Lurie DJ, Palma G
* New developments in MRI: System characterization, technical advances and radiotherapy applications (206 views)
Phys Med (ISSN: 1120-1797linking), 2021 Sep 16; 90: 50-52.
Impact Factor: 2.685
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Costanzo M, De Giglio MAR, Roviello GN
* Anti-Coronavirus Vaccines: Past Investigations on SARS-CoV-1 and MERS-CoV, the Approved Vaccines from BioNTech/Pfizer, Moderna, Oxford/AstraZeneca and others under Development Against SARS-CoV-2 Infection (163 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021 May 21; DOI:10.2174/09298673: 1-1.
Impact Factor: 4.53
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Moreira M, Ruggiero A, Iaccarino E, Barra G, Sandomenico A, Ruvo M, Berisio R
* A structure-based approach for the development of a bicyclic peptide acting as a miniaturized anti-CD55 antibody (169 views) (PDF 28 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2021 May 17; 182: 1455-1462.
Impact Factor: 6.95
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Di Giovannantonio LG, Acampora D, Omodei D, Nigro V, Barba P, Barbieri E, Chambers I, Simeone A
* Direct repression of Nanog and Oct4 by OTX2 modulates the contribution of epiblast-derived cells to germline and somatic lineage (101 views)
Development (ISSN: 0950-1991linking), 2021 May 15; 148(10): N/D-N/D.
Impact Factor: 5.611
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Sivaccumar JP, Leonardi A, Iaccarino E, Corvino G, Sanguigno L, Chambery A, Russo R, Valletta M, Latino D, Capasso D, Doti N, Ruvo M, Sandomenico A
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Impact Factor: 4.556
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Sivaccumar J, Sandomenico A, Vitagliano L, Ruvo M
* Monoclonal Antibodies: A Prospective and Retrospective View (160 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021; 28(3): 435-471.
Impact Factor: 4.184
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D’ambrosio K, Di Fiore A, Buonanno M, Kumari S, Tiwari M, Supuran CT, Mishra CB, Monti SM, De Simone G
* The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development (152 views)
New Journal Of Chemistry, 2021; 45: 147-152.
Impact Factor: 3.288
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Smaldone G, Ruggiero A, Balasco N, Vitagliano L
* Development of a Protein Scaffold for Arginine Sensing Generated through the Dissection of the Arginine-Binding Protein from Thermotoga maritima (209 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2020 Oct 12; 21(20): N/D-N/D.
Impact Factor: 4.556
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Megna R
* First month of the epidemic caused by COVID-19 in Italy: current status and real-time outbreak development forecast (522 views)
Glob Health Res Policy (ISSN: 2397-0642linking), 2020 Oct 1; 5: 43-43.
Impact Factor: 8.7
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Canassa-deleo T, Campo VL, Rodrigues LC, Marchiori MF, Fuzo C, Brigido MM, Sandomenico A, Ruvo M, Maranhao AQ, Dias-baruffi M
* Multifaceted antibodies development against synthetic alpha-dystroglycan mucin glycopeptide as promising tools for dystroglycanopathies diagnostic (224 views)
Glycoconj J (ISSN: 0282-0080linking), 2020 Feb; 37(1): 77-93.
Impact Factor: 2.197
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Maievskyi O, Samborska I, Kovalchuk O, Fagoonee S, Falalyeyeva T
* The Role of Hyperhomocysteinemia on the Development of Changes in the Lungs (173 views)
Rev Recent Clin Trials (ISSN: 1574-8871linking), 2020; 15(1): 48-59.
Impact Factor: 0.09
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Verdoliva V, Saviano M, De Luca S
Zeolites as Acid/Basic Solid Catalysts: Recent Synthetic Developments (248 views)
Catalyst, 2019 Aug; 9(3): 248-248.
Impact Factor: 3.465
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Russi S, Verma HK, Laurino S, Mazzone P, Storto G, Nardelli A, Zoppoli P, Calice G, La Rocca F, Sgambato A, Lucci V, Falco G, Ruggieri V
* Adapting and Surviving: Intra and Extra-Cellular Remodeling in Drug-Resistant Gastric Cancer Cells (216 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1661-6596, 1422-0067electronic), 2019 Jul 31; 20(15): N/D-N/D.
Impact Factor: 4.183
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Greco A, Ragucci M, Liuzzi R, Prota M, Cocchia N, Fatone G, Mancini M, Brunetti A, Meomartino L
* Noninvasive Ultrasound Monitoring of Embryonic and Fetal Development in Chinchilla lanigera to Predict Gestational Age: Preliminary Evaluation of This Species as a Novel Animal Model of Human Pregnancy (252 views)
Contrast Media Mol Imaging (ISSN: 1555-4309linking, 1555-4317electronic), 2019 May 27; 2019: 6319476-6319476.
Impact Factor: 4.02
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Foca G, Iaccarino E, Foca A, Sanguigno L, Untiveros G, Cuevas-nunez M, Strizzi L, Leonardi A, Ruvo M, Sandomenico A
* Development of conformational antibodies targeting Cripto-1 with neutralizing effects in vitro (650 views)
Biochimie (ISSN: 0300-9084linking, 1638-6183electronic), 2019 Mar; 158: 246-256.
Impact Factor: 3.787
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Caprio MG, Di Serafino M, De Feo A, Guerriero E, Perillo T, Barbuto L, Vezzali N, Rossi E, Ferro F, Vallone G, Orazi C
* Ultrasonographic and multimodal imaging of pediatric genital female diseases (258 views) (PDF 109 views)
J Ultrasound (ISSN: 1876-7931linking, 1876-7931electronic), 2019 Feb 19; 22(3): 273-289.
Impact Factor: 1.547
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Nicoletti F, Orlando R, Di Menna L, Cannella M, Notartomaso S, Mascio G, Iacovelli L, Matrisciano F, Fazio F, Caraci F, Copani A, Battaglia G, Bruno V
* Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia (221 views)
Front Psychiatry (ISSN: 1664-0640linking, 1664-0640electronic), 2019 Feb 14; 10: 49-49.
Impact Factor: 2.857
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Ricciardelli A, Casillo A, Vergara A, Balasco N, Corsaro MM, Tutino ML, Parrilli E
* Environmental conditions shape the biofilm of the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 (129 views)
Microbiol Res (ISSN: 0944-5013linking), 2019 Jan; 218: 66-75.
Impact Factor:
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Berisio R, Berisio R
* Molecular Biomarkers of Disease for Diagnosis and Drug Development (315 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2019; 26(11): 1922-1923.
Impact Factor: 3.9
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Conson M, Bianchini F, Quarantelli M, Boccia M, Salzano S, Di Vita A, Guariglia C
* Selective map-following navigation deficit: A new case of developmental topographical disorientation (350 views)
J Clin Exp Neuropsychol (ISSN: 1380-3395linking), 2018 Nov; 40(9): 940-950.
Impact Factor: 1.839
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Pontillo G, Cocozza S, Brunetti A, Brescia Morra V, Riccio E, Russo C, Sacca F, Tedeschi E, Pisani A, Quarantelli M
* Reduced Intracranial Volume in Fabry Disease: Evidence of Abnormal Neurodevelopment? (357 views)
Front Neurol (ISSN: 1664-2295linking, 1664-2295print), 2018 Aug 17; 9(AUG): 672-672.
Impact Factor: 3.508
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Marr K, Jakimovski D, Mancini M, Carl E, Zivadinov R
* Jugular Venous Flow Quantification Using Doppler Sonography (1369 views)
Ultrasound Med Biol (ISSN: 0301-5629linking, 1879-291xelectronic), 2018 Aug; 44(8): 1762-1769.
Impact Factor: 2.494
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Buonanno M, Coppola M, Di Lelio I, Molisso D, Leone M, Pennacchio F, Langella E, Rao R, Monti SM
* Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein (398 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Mar; 27(3): 620-632.
Impact Factor: 2.937
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Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F
* Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system (477 views)
Neuropharm (ISSN: 0028-3908linking, 1873-7064electronic), 2018 Jan; 128: 301-313.
Impact Factor: 3.383
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De Simone G, D'Ambrosio K
* Recent Advances in the Development of New Therapeutic Tools Against Major Parasitic Diseases (297 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018; 25(39): 5238-5238.
Impact Factor: 4.63
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Caraci F, Nicoletti F, Copani A
* Metabotropic glutamate receptors: the potential for therapeutic applications in Alzheimer's disease (737 views)
Curr Opin Pharmacol (ISSN: 1471-4892), 2017 Dec 23; 38: 1-7.
Impact Factor: 6.313
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Squeglia F, Romano M, Ruggiero A, Berisio R
* Molecular players in Tuberculosis drug development: another break in the cell wall (415 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3954-3969.
Impact Factor: 3.469
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Balasco N, Barone D, Sandomenico A, Ruggiero A, Doti N, Berisio R, Ruvo M, Vitagliano L
* Structural Versatility of Hepatitis C Virus Proteins: Implications for the Design of Novel Anti-HCV Intervention Strategies (351 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 4081-4101.
Impact Factor: 3.469
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Baglivo I, Pirone L, Pedone E, Pitzer JE, Muscariello L, Marino MM, Malgieri G, Freschi A, Chambery A, Roop Ii RM, Pedone PV
* Ml proteins from Mesorhizobium loti and MucR from Brucella abortus: an AT-rich core DNA-target site and oligomerization ability (327 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Nov 17; 7(1): 15805-15805.
Impact Factor: 4.122
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Meccariello A, Monti SM, Romanelli A, Colonna R, Primo P, Inghilterra MG, Del Corsano G, Ramaglia A, Iazzetti G, Chiarore A, Patti F, Heinze SD, Salvemini M, Lindsay H, Chiavacci E, Burger A, Robinson MD, Mosimann C, Bopp D, Saccone G
* Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes (404 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Aug 30; 7(1): 10061-10061.
Impact Factor: 4.122
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Caraci F, Bruno V, Copani A, Matrisciano F, Nicoletti F, Battaglia G
* The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders (369 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2017 Mar 15; 115: 180-192.
Impact Factor: 5.012
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Auletta L, Greco A, Albanese S, Meomartino L, Salvatore M, Mancini M
* Original Research: Feasibility and safety of two surgical techniques for the development of an animal model of jugular vein occlusion (501 views)
Exp Biol Med (ISSN: 1535-3699electronic, 1535-3699linking), 2017 Jan; 242(1): 22-28.
Impact Factor: 2.542
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Angapelly S, Ramya PVS, Angeli A, Monti SM, Buonanno M, Alvala M, Supuran CT, Arifuddin M
* Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors (314 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2017; 25(2): 539-544.
Impact Factor: 2.881
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Majkowska-skrobek G, Latka A, Berisio R, Maciejewska B, Squeglia F, RomanoM, Lavigne R, Struve C, Drulis-kawa Z
* Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy (501 views)
Viruses (ISSN: 1999-4915, 1999-4915linking, 1999-4915electronic), 2016 Dec 1; 8(12): N/D-N/D.
Impact Factor: 3.465
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Auletta L, Greco A, Albanese S, Meomartino L, Salvatore M, Mancini M
* Feasibility and safety of two surgical techniques for the development of an animal model of jugular vein occlusion (349 views)
Exp Biol Med (ISSN: 1535-3699electronic, 1535-3699linking), 2016 Jul 5; N/D: N/D-N/D.
Impact Factor: 2.542
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Gambardella J, Franco A, Giudice CD, Fiordelisi A, Cipolletta E, Ciccarelli M, Trimarco B, Iaccarino G, Sorriento D
* Dual role of GRK5 in cancer development and progression (222 views)
Transl Med Unisa (ISSN: 2239-9747electronic, 2239-9747linking), 2016 May 16; 14: 28-37.
Impact Factor: 2.256
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Calce E, Saviano M, De Luca S
Development of Targeting Ligands for HER2 Receptor: Simplified Receptor Model Employed for Selecting Highly Specific Molecules (282 views)
International Journal Of Peptide Research And Therapeutics, 2016; 22(2): 237-242.
Impact Factor: 0.99
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Merlino F, Brancaccio D, Yousif AM, Piras L, Campiglia P, Gomez-monterrey I, Santicioli P, Meini S, Maggi CA, Novellino E, Carotenuto A, Grieco P
* Structure-Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position9 (476 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7179linking), 2016; N/D: N/D-N/D.
Impact Factor: 3.225
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Di Fiore A, Vergara A, Caterino M, Alterio V, Monti SM, Ombouma J, Dumy P, Vullo D, Supuran CT, Winum JY, De Simone G
* Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors (395 views) (PDF 243 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2015 Jul 2; 51(57): 11519-11522.
Impact Factor: 6.567
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Cipolletta E, Rusciano MR, Maione AS, Santulli G, Sorriento D, Del Giudice C, Ciccarelli M, Franco A, Crola C, Campiglia P, Sala M, Gomez-Monterrey I, De Luca N, Trimarco B, Iaccarino G, Illario M
* Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy (328 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Jun 25; 10(6): e0130477-e0130477.
Impact Factor: 3.057
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Alterio V, Langella E, De Simone G, Monti SM
* Cadmium-containing carbonic anhydrase CDCA1 in marine diatom Thalassiosira weissflogii (848 views)
Mar Drugs (ISSN: 1660-3397, 1660-3397linking), 2015 Mar 25; 13(4): 1688-1697.
Impact Factor: 3.345
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Squeglia F, Ruggiero A, Berisio R
* Exit from mycobacterial dormancy: a structural perspective (696 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
Impact Factor: 3.455
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Antonini D, Sirico A, Aberdam E, Ambrosio R, Campanile C, Fagoonee S, Altruda F, Aberdam D, Brissette JL, Missero C
* A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms (1066 views)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962), 2015 Jan; 43(2): 862-874.
Impact Factor: 9.202
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (1977 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Albanese S, Auletta L, Zannetti A, Di Maro G, Mirabelli P, D'Alterio C, Salvatore G, Soricelli A, Salvatore M, Greco A
* High Frequency Ultrasound for the development of an Orthotopic mouse model of Human Follicular Thyroid Carcinoma (412 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2015; 42: S416-S416.
Impact Factor: 5.537
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Hangen E, Féraud O, Lachkar S, Mou H, Doti N, Fimia GM, Lam N-V, Zhu C, Godin I, Muller K, Chatzi A, Nuebel E, Ciccosanti F, Flamant S, Bénit P, Perfettini J-L, Sauvat A, Bennaceur-Griscelli A, Ser-Le Roux K, Gonin P, Tokatlidis K, Rustin P, Piacentini M, Ruvo M, Blomgren K, Kroemer G, Modjtahedi N
* Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis (796 views)
Mol Cell (ISSN: 1097-2765, 1097-4164), 2015; 58(6): 1001-1014.
Impact Factor: 13.958
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Milardi D, Pappalardo M
* Molecular dynamics: New advances in drug discovery (511 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 91: 1-3.
Impact Factor: 3.902
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Rizzarelli E, Vecchio G, Puglisi A, La Mendola D, Pugliesi A
* New Conjugate Of Cyclodextrin Useful As Anti-Inflammatory And Anti-Tumoral Agents And For Preparation Of Medicaments With Colon Site-Specific Delivery (330 views)
Am J Obstet Gynecol (ISSN: 0002-9378), 2015; 212(3): 413-413.
Impact Factor: 4.681
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Iqbal J, Al-rashida M, Durdagi S, Alterio V, Di Fiore A
* Recent developments of carbonic anhydrase inhibitors as potential drugs (670 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2015; 2015: 174178-174178.
Impact Factor: 2.134
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Morelli G, Saviano M, Grieco P
* The renaissance era of peptides in drug discovery at the 14th Naples workshop on bioactive peptides (562 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 321-322.
Impact Factor: 1.951
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Gargiulo S, Gramanzini M, Megna R, Greco A, Albanese S, Manfredi C, Brunetti A
* Evaluation of growth patterns and body composition in C57Bl/6J mice using dual energy X-ray absorptiometry (708 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2014 Jul; 2014: 253067-253067.
Impact Factor: 1.579
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Calce E, Mignogna E, Bugatti V, Galdiero M, Vittoria V, De Luca S
* Pectin functionalized with natural fatty acids as antimicrobial agent (521 views)
Int J Biol Macromol (ISSN: 0141-8130, 0141-8130linking, 1879-0003electronic), 2014 Jul; 68: 28-32.
Impact Factor: 2.858
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Bilo L, Peluso S, Antenora A, De Rosa A, Auletta G, Pappata S, De Michele G
* Parkinsonism may be part of the symptom complex of DOOR syndrome (354 views)
Parkinsonism Relat D (ISSN: 1353-8020, 1873-5126, 1353-8020print), 2014 Apr; 20(4): 463-465.
Impact Factor: 3.972
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Troise AD, Dathan NA, Fiore A, Roviello G, Di Fiore A, Caira S, Cuollo M, De Simone G, Fogliano V, Monti SM
* Faox enzymes inhibited Maillard reaction development during storage both in protein glucose model system and low lactose UHT milk (297 views)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014 Feb; 46(2): 279-288.
Impact Factor: 3.293
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Orlandini S, Pasquini B, Gotti R, Giuffrida A, Paternostro F, Furlanetto S
* Analytical quality by design in the development of a cyclodextrin-modified capillary electrophoresis method for the assay of metformin and its related substances (317 views)
Electrophoresis (ISSN: 0173-0835), 2014; 35(17): 2538-2545.
Impact Factor: 3.028
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Greco A, Ragucci M, Coda ARD, Rosa A, Gargiulo S, Liuzzi R, Gramanzini M, Albanese S, Pappata S, Mancini M, Brunetti A, Salvatore M
* Correction: High frequency ultrasound for in vivo pregnancy diagnosis and staging of placental and fetal development in mice (PLoS ONE) (354 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2014; 9(1): N/D-N/D.
Impact Factor: 3.234
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De Simone G, Pizika G, Monti SM, Di Fiore A, Ivanova J, Vozny I, Trapencieris P, Zalubovskis R, Supuran CT, Alterio V
* Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors (376 views)
Biomed Res Int (ISSN: 2314-6133, 2314-6141), 2014; 2014: 523210-523210.
Impact Factor: 1.579
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Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S
* Structure-Activity Relations of Myxinidin, an Antibacterial Peptide Derived from the Epidermal Mucus of Hagfish (926 views)
Antimicrob Agents Ch (ISSN: 0066-4804, 1098-6596), 2013 Nov; 57(11): 5665-5673.
Impact Factor: 4.451
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Greco A, Ragucci M, Coda ARD, Rosa A, Gargiulo S, Liuzzi R, Gramanzini M, Albanese S, Pappata S, Mancini M, Brunetti A, Salvatore M
* High frequency ultrasound for in vivo pregnancy diagnosis and staging of placental and fetal development in mice (491 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Oct 14; 8(10): e77205-e77205.
Impact Factor: 3.534
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Portella L, Vitale R, De Luca S, D'Alterio C, Ieranò C, Napolitano M, Riccio A, Polimeno MN, Monfregola L, Barbieri A, Luciano A, Ciarmiello A, Arra C, Castello G, Amodeo P, Scala S
* Preclinical Development of a Novel Class of CXCR4 Antagonist Impairing Solid Tumors Growth and Metastases (579 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Sep 13; 8(9): N/D-N/D.
Impact Factor: 3.534
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Lombardo B, Rocco T, Esposito MT, Cantilena B, Gargiulo S, Greco A, Montanaro D, Brunetti A, Pastore L
* Thymidine Kinase-Mediated Shut Down of Bone Morphogenetic Protein-4 Expression Allows Regulated Bone Production (569 views)
Current Gene Therapy (ISSN: 1566-5232, 1875-5631), 2013 Jun 1; 13(3): 202-210.
Impact Factor: 4.906
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Accardo A, Tesauro D, Morelli G
* Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (539 views)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Impact Factor: 1.554
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D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (440 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
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Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Development of multivariate NTCP models for radiation-induced hypothyroidism: A comparative analysis (535 views) (PDF 252 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2012 Dec 27; 7(1): 224-224.
Impact Factor: 2.107
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Berisio R
* Learning from pathogens: Exploiting host-pathogen liaison for therapeutic development (668 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2012 Dec; 13(8): 697-698.
Impact Factor: 2.326
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Balbi L, Greco D, Innocenti S, Sirignano C, Palma G, Soscia E, Alfano B, Salvatore M
* T2 & T2ρ Maps: Sequence Development And Clinical Impact On Joint Study (447 views) (PDF 250 views)
Ecr 2012, 2012 Oct; N/D: C-2444.
Impact Factor: 0
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Soscia E, Sirignano C, Catalano O, Atteno M, Costa L, Caso F, Peluso R, Bruner V, Aquino MM, Del Puente A, Salvatore M, Scarpa R
* New developments in magnetic resonance imaging of the nail unit (490 views)
Journal Of Rheumatology (ISSN: 0315-162x), 2012 Jul; 39(SUPPL.89): 49-53.
Impact Factor: 3.258
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Di Maro A, Berisio R, Ruggiero A, Tamburino R, Severino V, Zacchia E, Parente A
* Structural and enzymatic properties of an in vivo proteolytic form of PD-S2, type 1 ribosome-inactivating protein from seeds of Phytolacca dioica (475 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 May 11; 421(3): 514-520.
Impact Factor: 2.406
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Paladini D, Quarantelli M, Pastore G, Sorrentino M, Sglavo G, Nappi C
* Abnormal or delayed development of the posterior membranous area of the brain: Anatomy, ultrasound diagnosis, natural history and outcome of Blake's pouch cyst in the fetus (644 views)
Ultrasound Obst Gyn (ISSN: 0960-7692, 1469-0705), 2012 Mar; 39(3): 279-287.
Impact Factor: 3.557
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Calafiore M, Copani A, Deng W
* DNA polymerase-β mediates the neurogenic effect of β-amyloid protein in cultured subventricular zone neurospheres (701 views)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2012 Mar; 90(3): 559-567.
Impact Factor: 2.974
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Paladini D, Quarantelli M, Pastore G, Sorrentino M, Sglavo G, Nappi C
* Abnormal Or Delayed Development Of The Area Membranacea Posterior Of The Brain: The Blake'S Pouch Cyst. Anatomy, Ultrasound Diagnosis, Natural History And Outcome In The Fetus (429 views)
Ultrasound Obstet Gynecol, 2012; 39: 279-287.
Impact Factor: 4.368
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D'Ambrosio K, Smaine F-Z, Carta F, De Simone G, Winum J-Y, Supuran CT
* Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups (552 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2012; 55(15): 6776-6783.
Impact Factor: 5.614
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Di Fiore A, Maresca A, Supuran CT, De Simone G
* Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors (417 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2012; 48(70): 8838-8840.
Impact Factor: 6.378
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Greco A, Mancini M, Gargiulo S, Gramanzini M, Claudio PP, Brunetti A, Salvatore M
* Ultrasound biomicroscopy in small animal research: Applications in molecular and preclinical imaging (763 views)
J Biomed Biotechnol (ISSN: 1110-7243, 1110-7251), 2012; 2012: 519238-519238.
Impact Factor: 2.88
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Falanga A, Vitiello MT, Cantisani M, Tarallo R, Guarnieri D, Mignogna E, Netti P, Pedone C, Galdiero M, Galdiero S
* A peptide derived from herpes simplex virus type 1 glycoprotein H: membrane translocation and applications to the delivery of quantum dots (1365 views)
Nanomedicine (ISSN: 1549-9642, 1549-9634, 1549-9642electronic), 2011 Dec; 7(6): 925-934.
Impact Factor: 6.692
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Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
* A versatile strategy for signal amplification based on core/shell silica nanoparticles (596 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Nov 25; 17(48): 13429-13432.
Impact Factor: 5.925
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Durazzo M, Campion D, Fagoonee S, Pellicano R, Sonne JU, Erckenbrecht JF, Grassi M, Petraccia L, Mennuni G, Fontana M, Scarno A, Sabetta S, Fraioli A
* Changes, functional disorders, and diseases in the gastrointestinal tract of elderly (223 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking, 1432-1289electronic), 2011 Jul; 2655108(6): 659-668.
Impact Factor: 0.913
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Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (388 views) (PDF 238 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
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Soscia E, Palma G, Sirignano C, Iodice D, Innocenti S, Greco D, Alfano B, Salvatore M
* Relaxometric Maps: Sequence Development And Clinical Impact. Initial Observations (453 views) (PDF 200 views)
Ecr 2011, 2011 Mar; 10.1594/ecr2011/C-09: C-0998.
Impact Factor: 0
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Sirignano C, Soscia E, Iodice D, Innocenti S, Palma G, Greco D, Balbi L, Alfano B, Salvatore M
* T2 & T2ρ Maps: Sequence Development And Clinical Impact On Joint Study (1288 views) (PDF 238 views)
Ismrm March 2011, 2011 Mar; N/D: N/D-N/D.
Impact Factor: 0
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Pizzo E, Merlino A, Turano M, Russo Krauss I, Coscia F, Zanfardino A, Varcamonti M, Furia A, Giancola C, Mazzarella L, Sica F, D'Alessio G
* A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish (961 views)
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2011 Jan 15; 433(2): 345-355.
Impact Factor: 4.897
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Monfregola L, Leone M, Vittoria V, Amodeo P, De Luca S
* Chemical modification of pectin: Environmental friendly process for new potential material development (354 views)
Polym Chem (ISSN: 1759-9954), 2011; 2(4): 800-804.
Impact Factor: 5.321
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Amorosi S, Vigliano I, Del Giudice E, Panico L, Maruotti GM, Fusco A, Quarantelli M, Ciccone C, Ursini MV, Martinelli P, Pignata C
* Brain alteration in a Nude/SCID fetus carrying FOXN1 homozygous mutation (615 views)
J Neurol Sci (ISSN: 0022-510x, 0022-510xlinking), 2010 Nov 15; 298(1-2): 121-123.
Impact Factor: 2.167
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Calvanese L, Marasco D, Doti N, Saporito A, D'Auria G, Paolillo L, Ruvo M, Falcigno L
* Structural Investigations on the Nodal-Cripto Binding: A Theoretical and Experimental Approach (653 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 Nov; 93(11): 1011-1021.
Impact Factor: 2.572
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Avitabile C, Moggio L, D'Andrea LD, Pedone C, Romanelli A
* Development of an efficient and low-cost protocol for the manual PNA synthesis by Fmoc chemistry (634 views)
Tetrahedron Lett (ISSN: 0040-4039), 2010 Jul 21; 51(29): 3716-3718.
Impact Factor: 2.618
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Pensato S, Renda M, Leccia F, Saviano M, D'Andrea LD, Pedone C, Pedone PV, Romanelli A
* PNA zipper as a dimerization tool: development of a bZip mimic (717 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010 May; 93(5): 434-441.
Impact Factor: 2.572
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Di Stasi R, Diana D, Capasso D, Palumbo R, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD
* VEGFR1(D2) in drug discovery: Expression and molecular characterization (600 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010; 94(6): 800-809.
Impact Factor: 2.572
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Calvanese L, Saporito A, Oliva R, D'Auria G, Pedone C, Paolillo L, Ruvo M, Marasco D, Falcigno L
* Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor (581 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 175-183.
Impact Factor: 1.807
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Doti N, Marasco D, Sabatella M, Monti SM, Dathan N, Viparelli F, Cassese A, Miele C, Pedone C, Ruvo M
* An analysis of deletion mutants of the PLD1 D4 domain defines short regions within the PLD1 interacting with PED/PEA15: implications for the development of peptides-specific antagonist (480 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Zaccaro L, Del Gatto A, Saviano M, Langella E, Langlois C, Di Lello P, Baffreau J, Mas C, Legault P, Omichinski JG, Pedone C
* Development of new molecules that compete with p53 for Binding to TFIIH (435 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
* The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development (543 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2008; 15(24): 2420-2432.
Impact Factor: 4.823
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Russo M, Meomartino L, Greco A, Catone G, Cocchia N, Tortora G, Brunetti A
* Pregnancy detection in mice using ultrasound (504 views)
Vet Rec (ISSN: 0042-4900), 2007 Mar 31; 160(13): 446-447.
Impact Factor: 1.087
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Volpe P, Paladini D, Resta M, Stanziano A, Salvatore M, Quarantelli M, De Robertis V, Buonadonna AL, Caruso G, Gentile M
* Characteristics, associations and outcome of partial agenesis of the corpus callosum in the fetus (460 views)
Ultrasound Obst Gyn (ISSN: 0960-7692, 1469-0705), 2006 May; 27(5): 509-516.
Impact Factor: 2.288
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D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (954 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285, 1747-0277linking), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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Bernini E De Nuccio R, Brescia F, Minardo A, Zeni L, Sarro PM, Palumbo R, Scarf MR
* Development and characterization of an integrated silicon micro flow cytometer (415 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2006; 386(5): 1267-1272.
Impact Factor: 2.591
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Saviano M, Zaccaro L, Benedetti E, Pedone C, Del Gatto A, Feliciello A, Affaiatati A, Avvedimento EV
* Development of peptides able to modulate the interaction of AKAP121 with mitochondria (516 views)
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
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Le Provost JB, Bartres-faz D, Paillere-martinot ML, Artiges E, Pappata S, Recasens C, Perez-gomez M, Bernardo M, Baeza I, Bayle F, Martinot JL
* Paracingulate sulcus morphology in men with early-onset schizophrenia (373 views)
Br J Psychiatry (ISSN: 0007-1250), 2003 Mar; 182(MAR.): 228-232.
Impact Factor: 4.421
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Kozarski M, Ferrari G, Clemente F, Gorczynska K, De Lazzari C, Darowski M, Mimmo R, Tosti G, Guaragno M
* A hybrid mock circulatory system: development and testing of an electro-hydraulic impedance simulator (415 views)
Int J Artif Organs (ISSN: 0391-3988, 0391-3988print), 2003 Jan; 26(1): 53-63.
Impact Factor: 0.964
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Accardo A, Ricci F, Basso P, Lega M
* Development Approach And Testing Of An Unmanned Aerial Vehicle (278 views)
23rd International Council Of Aeronautical Sciences Toronto Canada, 2002; N/D: 13-13.
Impact Factor: 4.622
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Dathan N, Parlato R, Rosica A, De Felice M, Di Lauro R
* Distribution Of The Titf2/Foxe1 Gene Product Is Consistent With An Important Role In The Development Of Foregut Endoderm, Palate, And Hair (301 views)
Developmental Dynamics, 2002; 224: 450-456.
Impact Factor: 2.668
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (614 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Lombardi G, Colao A, Cuocolo A, Longobardi S, Di Somma C, Orio F, Merola B, Nicolai E, Salvatore M
Cardiological aspects of growth hormone and insulin-like growth factor- (1049 views)
J Pediatr Endocrinol Metab (ISSN: 0334-018x), 1997 Nov; 10(6): 553-560.
Impact Factor: 0.481
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Gomez Palacios LR, Bracamonte AG
Development of nano- and microdevices for the next generation of biotechnology, wearables and miniaturized instrumentation (56 views)
Rsc Adv (ISSN: 2046-2069electronic), N/D; 12 (20 ): 12806-12822.
Impact Factor: 3.84
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109 Records (98 excluding Abstracts).
Total impact factor: 372.93 (341.26 excluding Abstracts).
Total 5 year impact factor: 354.9 (321.499 excluding Abstracts).
Total impact factor: 372.93 (341.26 excluding Abstracts).
Total 5 year impact factor: 354.9 (321.499 excluding Abstracts).
64 views. Last view on Saturday 28 September 2024, 15:00:22
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