Novel ligands for the affinity-chromatographic purification of antibodies (1313 views)
J Biochem Biophys Methods (ISSN: 0165-022x, 0165-022xlinking), 2001 Oct 30; 49(1-3): 481-490.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Review,
Impact factor: 1.218, 5-year impact factor: 4.95
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035975879&partnerID=40&md5=a6c805aafb8beb9894e64070740335ca
Keywords: Affinity Chromatography, Antibodies, Combinatorial Chemistry, Molecular Design, Synthetic Ligands, Immunoglobulin, Lectin, Protein, Tg 19318, Unclassified Drug, Bioavailability, Biosynthesis, Biotechnology, Diagnostic Procedure, Dna Modification, Methodology, Microorganism, Molecular Model, Priority Journal, Protein Purification, Protein Targeting, Review, Technique, Combinatorial Chemistry Techniques, Peptide Library, Staphylococcal Protein A, Isolation,
Affiliations:
*** IBB - CNR ***
Biopharmaceuticals, TECNOGEN, Parco Scientifico, 81015 Piana di Monte Verna (CE), Italy
References:
Fuglistaller, P., Comparison of immunoglobulin binding capacities and ligand leakage using eight different protein A affinity chromatography matrices (1989) J Immunol Methods, 124, pp. 171-17
Michetti, P., Mahan, M.J., Slauch, J.M., Mekelanos, J.J., Neutra, M.R., Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium (1992) Infect Immun, 60, pp. 1786-1792
Phalipon, A., Kaufmann, M., Michetti, P., Cavaillon, J.M., Huerre, M., Sansonetti, P., Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis (1995) J Exp Med, 182, pp. 769-778
Apter, F.M., Lencer, W.I., Finkelstein, R.A., Mekalanos, J.J., Neutra, M.R., Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro (1993) Infect Immun, 61, pp. 5271-5278
Weltzin, R., Hsu, S.A., Mittler, E.S., Georgakopoulos, K., Monath, T.P., Intranasal monoclonal immunoglobulin A against respiratory syncytial virus protects against upper and lower respiratory tract infections in mice (1994) Antimicrob Agents Chemother, 38, pp. 2785-2791
Waldam, R.H., Mach, J.P., Stella, M.M., Rowe, D.S., Secretory IgA in human serum (1970) J Immunol, 105, pp. 43-47
Khayam-Bashi, H., Blanken, R.M., Schwartz, C.L., Chromatographic separation and purification of secretory IgA from human milk (1977) Prep Biochem, 7, pp. 225-229
Roque-Barreira, M.R., Campos-Nieto, A., Jacalin: An IgA-binding lectin (1985) J Biol Chem, 134, pp. 1740-1743
Kondoh, H., Kobayashi, K., Hagiwara, K., A simple procedure for the isolation of human secretory IgA of IgA1 and IgA2 subclass by a jackfruit lectin, jacalin, affinity chromatography (1987) Mol Immunol, 24, pp. 1219-1222
Bunn-Moreno, M.M., Campos-Neto, A., Lectin(s) extracted from seeds of artocarpus integrifolia (jackfruit): Potent and selective stimulator(s) of distinct human T and B cell functions (1981) J Immunol, 127, pp. 427-430
Nagy, E., Berczi, I., Sehon, A.H., Growth inhibition of murine mammary carcinoma by monoclonal IgE antibodies specific for the mammary tumor virus (1991) Cancer Immunol Immunother, 34, pp. 63-69
Phillips, T.M., More, N.S., Queen, W.D., Thompson, A.M., Isolation and quantitation of serum IgE levels by high-performance immunoaffinity chromatography (1985) J Chromatogr, 327, pp. 205-211
Lehrer, S.B., Isolation of IgE from normal mouse serum (1979) Immunology, 36, pp. 103-109
Ikeyama, S., Nakagawa, S., Arakawa, M., Sugino, H., Kakinuma, A., Purification and characterization of IgE produced by human myeloma cell line, U266 (1986) Mol Immunol, 23, pp. 159-167
Quadri, S.M., Malik, A.B., Tang, X.Z., Patenia, R., Freedman, R.S., Vriesendorp, H.M., Preclinical analysis of intraperitoneal administration of 111In-labeled human tumor reactive monoclonal IgM AC63-2B12 (1995) Cancer Res, 55, pp. 5736-5742
Nevens, J.R., Mallia, A.K., Wendt, M.W., Smith, P.K., Affinity chromatographic purification of immunoglobulin M antibodies utilizing immobilized mannan binding protein (1992) J Chromatogr, 597, pp. 247-253
Polson, A., Von Wechmar, M.B., Van Regenmortel, M.H.V., Isolation of viral IgY antibodies from egg yolks of immunized hens (1980) Immunol Commun, 9, pp. 475-493
Jensenius, J.C., Anderson, I., Hau, J., Crove, M., Koch, C., Eggs: Conveniently packaged antibodies. Methods for purification of yolk IgG (1981) J Immunol Methods, 46, pp. 63-68
Carrol, S.B., Stollar, B.D., Antibodies to calf thymus RNA polymerase II from egg yolks of immunized hens (1983) J Biol Chem, 258, pp. 24-26
Akita, E.M., Nakai, S., Comparison of four purification methods for the production of immunoglobulins from eggs laid by hens immunized with an enteroxigenic E. coli strain (1993) J Immunol Methods, 160, pp. 207-214
Hatta, H., Tsuda, K., Akachi, S., Kim, M., Yamamoto, T., Productivity and some properties of egg yolk antibodies (IgY) against human rotarovirus compared with rabbit IgG (1993) Biosci, Biotechnol, Biochem, 57, pp. 450-454
Gassmann, M., Thommes, P., Weiser, T., Hubscher, U., Efficient production of chicken egg yolk antibodies against a conserved mammalian protein (1990) FASEB J, 4, pp. 2528-2532
Song, C.-S., Yu, J.-H., Bai, D.H., Hester, P.Y., Kim, K.-H., Antibodies to a-subunit of insulin receptor from eggs of immunized hens (1985) J Immunol, 135, pp. 3354-3360
Larsson, A., Sjoquist, J., Chicken IgY: Utilizing the evolutionary difference (1990) Comp Immunol Microbiol Infect Dis, 13, pp. 199-201
Larsson, A., Sjöquist, J., Chicken antibodies: A tool to avoid false positive results by rheumatoid factor in latex fixation tests (1988) J Immunol Methods, 108, pp. 205-208
Kronvall, G., Seal, U.S., Svensson, S., Williams R.C., Jr., Phylogenetic aspects of staphylococcal Protein A-reactive serum globulins in birds and mammals (1974) Acta Pathol Microbiol Scand, Sect B: Microbiol Immunol, 82, pp. 12-18
Shibusawa, Y., Kihira, S., Ito, Y., One-step purification of proteins from chicken egg white using counter-current chromatography (1998) J Chromatogr, B: Biomed Sci Appl, 709, pp. 301-305
Hansen, P., Scoble, J.A., Hanson, B., Hoogenraad, N.J., Isolation and purification of immunoglobulins from chicken eggs using thiophilic interaction chromatography (1998) J Immunol Methods, 215, pp. 1-7
Hatta, H., Kim, M., Yamamoto, T., A novel isolation method for hen egg yolk antibody, "IgY" (1990) Agric Biol Chem, 54, pp. 2531-2535
Polson, A., Isolation of IgY from the yolks of eggs by a chloroform polyethylene glycol procedure (1990) Immunol Invest, 3, pp. 253-258
Polson, A., Coetzer, T., Kruger, J., Von Maltzahn, E., Van der Merwe, K.J., Improvements in the isolation of IgY from the yolks of eggs laid by immunized hens (1985) Immunol Invest, 4, pp. 323-327
Hassl, A., Aspöck, H., Purification of egg yolk immunoglobulins. A two-step procedure using hydrophobic interaction chromatography and gel filtration (1988) J Immunol Methods, 110, pp. 225-228
Porath, J., Belew, M., Thiophilic interaction and the selective adsorption of proteins (1987) Trends Biotechnol, 5, pp. 225-229
Elkak, A., Vjiayalakshmi, M.A., Study of the separation of mouse monoclonal-antibodies by pseudobioaffinity chromatography using matrix-linked histidine and histamine (1991) J Chromatogr, Biomed Appl, 570, pp. 29-41
Ngo, T.T., Khatter, N., Chemistry and preparation of affinity ligands useful in immunoglobulin isolation and serum-protein separation (1990) J Chromatogr, 510, pp. 281-291
Fassina, G., Verdoliva, A., Odierna, M.R., Ruvo, M., Cassani, G., Protein A mimetic peptide ligand for affinity purification of antibodies (1996) J Mol Recognit, 9, pp. 564-569
Houghten, R.A., Pinilla, C., Blondelle, S.E., Appel, J.R., Dooley, C.T., Cuervo, J.H., Generation and use of synthetic peptide combinatorial libraries for basic research and discovery (1991) Nature, 354, pp. 84-86
Lam, K.S., Salmon, S.E., Hersh, E.M., Hruby, V.J., Kazmiersky, W.M., Knapp, R.J., A new type of synthetic peptide library for identifying ligand-binding activity (1991) Nature, 354, pp. 82-84
Fassina, G., Oriented immobilization of peptide ligands on solid supports (1992) J Chromatogr, 591, pp. 99-106
Fournier, A., Couvineau, A., Laburthe, M., Synthesis of a hydrophilic affinity matrix for the purification of the vasoactive intestinal peptide receptor (1993) Anal Biochem, 211, pp. 305-310
Butz, S., Rawer, S., Rapp, W., Birsner, U., Immunization and affinity purification of antibodies using resin-immobilized lysine-branched synthetic peptides (1994) Pept Res, 7, pp. 20-23
Tam, J.P., Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system (1988) Proc Natl Acad Sci U S A, 85, pp. 5409-5413
Ruvo, M., Scardino, P., Cassani, G., Fassina, G., Facile manual synthesis of peptide libraries (1994) Protein Pept Lett, 1, pp. 187-192
Guerrier, L., Flayeuux, I., Schwarz, A., Fassina, G., Boschetti, E., IRIS97: An innovative protein A-peptidomimetic solid phase media for antibody purification (1998) J Mol Recognit, 11, pp. 107-109
Verdoliva, A., Basile, G., Fassina, G., Affinity purification of immunoglobulins from chicken egg yolk using a new synthetic ligand (2000) J Chromatogr, Biomed Appl, 749, pp. 233-242
Marino, M., Ruvo, M., De Falco, S., Fassina, G., Prevention of systemic lupus erythematosus in MRL/lpr mice by administration of an immunoglobulin binding peptide (2000) Nat Biotechnol, 18, pp. 735-739
Palombo, G., Verdoliva, A., Fassina, G., Affinity purification of IgM using a novel synthetic ligand (1998) J Chromatogr, Biomed Appl, 715, pp. 137-145
Palombo, G., De Falco, S., Tortora, M., Cassani, G., Fassina, G., A synthetic ligand for IgA affinity purification (1998) J Mol Recognit, 11, pp. 243-246
Palombo, G., Rossi, M., Cassani, G., Fassina, G., Affinity purification of mouse monoclonal IgE using a protein A mimetic ligand [TG 19318] immobilized on solid supports (1998) J Mol Recognit, 11, pp. 247-249
Fassina, G., Scardino, P., Ruvo, M., Fucile, P., Amodeo, P., Cassani, G., Synthesis of conformationally constrained dimeric peptide libraries (1995) Peptides 1994, pp. 489-490. , Maia H, editor. Leiden: ESCOM
Marino, M., Campanile, N., Ippolito, A., Scarallo, A., Ruvo, M., Fassina, G., Structurally constrained selective ligands for mouse immunoglobulins (1999) Peptides 98, pp. 776-777. , Bajusz S, Hudecz F, editors. Budapest: Academia Kiado
Li, R., Dowd, V., Steward, D.J., Burton, S.J., Lowe, C.R., Design, synthesis, and application of a protein A mimetic (1998) Nat Biotechnol, 16, pp. 190-195
Apter, F. M., Lencer, W. I., Finkelstein, R. A., Mekalanos, J. J., Neutra, M. R., Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro (1993) Infect Immun, 61, pp. 5271-5278
Waldam, R. H., Mach, J. P., Stella, M. M., Rowe, D. S., Secretory IgA in human serum (1970) J Immunol, 105, pp. 43-47
Roque-Barreira, M. R., Campos-Nieto, A., Jacalin: An IgA-binding lectin (1985) J Biol Chem, 134, pp. 1740-1743
Bunn-Moreno, M. M., Campos-Neto, A., Lectin (s) extracted from seeds of artocarpus integrifolia (jackfruit): Potent and selective stimulator (s) of distinct human T and B cell functions (1981) J Immunol, 127, pp. 427-430
Phillips, T. M., More, N. S., Queen, W. D., Thompson, A. M., Isolation and quantitation of serum IgE levels by high-performance immunoaffinity chromatography (1985) J Chromatogr, 327, pp. 205-211
Lehrer, S. B., Isolation of IgE from normal mouse serum (1979) Immunology, 36, pp. 103-109
Quadri, S. M., Malik, A. B., Tang, X. Z., Patenia, R., Freedman, R. S., Vriesendorp, H. M., Preclinical analysis of intraperitoneal administration of 111In-labeled human tumor reactive monoclonal IgM AC63-2B12 (1995) Cancer Res, 55, pp. 5736-5742
Nevens, J. R., Mallia, A. K., Wendt, M. W., Smith, P. K., Affinity chromatographic purification of immunoglobulin M antibodies utilizing immobilized mannan binding protein (1992) J Chromatogr, 597, pp. 247-253
Jensenius, J. C., Anderson, I., Hau, J., Crove, M., Koch, C., Eggs: Conveniently packaged antibodies. Methods for purification of yolk IgG (1981) J Immunol Methods, 46, pp. 63-68
Carrol, S. B., Stollar, B. D., Antibodies to calf thymus RNA polymerase II from egg yolks of immunized hens (1983) J Biol Chem, 258, pp. 24-26
Akita, E. M., Nakai, S., Comparison of four purification methods for the production of immunoglobulins from eggs laid by hens immunized with an enteroxigenic E. coli strain (1993) J Immunol Methods, 160, pp. 207-214
Song, C. -S., Yu, J. -H., Bai, D. H., Hester, P. Y., Kim, K. -H., Antibodies to a-subunit of insulin receptor from eggs of immunized hens (1985) J Immunol, 135, pp. 3354-3360
Larsson, A., Sj quist, J., Chicken antibodies: A tool to avoid false positive results by rheumatoid factor in latex fixation tests (1988) J Immunol Methods, 108, pp. 205-208
Hassl, A., Asp ck, H., Purification of egg yolk immunoglobulins. A two-step procedure using hydrophobic interaction chromatography and gel filtration (1988) J Immunol Methods, 110, pp. 225-228
Ngo, T. T., Khatter, N., Chemistry and preparation of affinity ligands useful in immunoglobulin isolation and serum-protein separation (1990) J Chromatogr, 510, pp. 281-291
Houghten, R. A., Pinilla, C., Blondelle, S. E., Appel, J. R., Dooley, C. T., Cuervo, J. H., Generation and use of synthetic peptide combinatorial libraries for basic research and discovery (1991) Nature, 354, pp. 84-86
Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmiersky, W. M., Knapp, R. J., A new type of synthetic peptide library for identifying ligand-binding activity (1991) Nature, 354, pp. 82-84
Tam, J. P., Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system (1988) Proc Natl Acad Sci U S A, 85, pp. 5409-5413
J Biochem Biophys Methods (ISSN: 0165-022x, 0165-022xlinking), 2001 Oct 30; 49(1-3): 481-490.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Review,
Impact factor: 1.218, 5-year impact factor: 4.95
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035975879&partnerID=40&md5=a6c805aafb8beb9894e64070740335ca
Keywords: Affinity Chromatography, Antibodies, Combinatorial Chemistry, Molecular Design, Synthetic Ligands, Immunoglobulin, Lectin, Protein, Tg 19318, Unclassified Drug, Bioavailability, Biosynthesis, Biotechnology, Diagnostic Procedure, Dna Modification, Methodology, Microorganism, Molecular Model, Priority Journal, Protein Purification, Protein Targeting, Review, Technique, Combinatorial Chemistry Techniques, Peptide Library, Staphylococcal Protein A, Isolation,
Affiliations:
*** IBB - CNR ***
Biopharmaceuticals, TECNOGEN, Parco Scientifico, 81015 Piana di Monte Verna (CE), Italy
References:
Fuglistaller, P., Comparison of immunoglobulin binding capacities and ligand leakage using eight different protein A affinity chromatography matrices (1989) J Immunol Methods, 124, pp. 171-17
Michetti, P., Mahan, M.J., Slauch, J.M., Mekelanos, J.J., Neutra, M.R., Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium (1992) Infect Immun, 60, pp. 1786-1792
Phalipon, A., Kaufmann, M., Michetti, P., Cavaillon, J.M., Huerre, M., Sansonetti, P., Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis (1995) J Exp Med, 182, pp. 769-778
Apter, F.M., Lencer, W.I., Finkelstein, R.A., Mekalanos, J.J., Neutra, M.R., Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro (1993) Infect Immun, 61, pp. 5271-5278
Weltzin, R., Hsu, S.A., Mittler, E.S., Georgakopoulos, K., Monath, T.P., Intranasal monoclonal immunoglobulin A against respiratory syncytial virus protects against upper and lower respiratory tract infections in mice (1994) Antimicrob Agents Chemother, 38, pp. 2785-2791
Waldam, R.H., Mach, J.P., Stella, M.M., Rowe, D.S., Secretory IgA in human serum (1970) J Immunol, 105, pp. 43-47
Khayam-Bashi, H., Blanken, R.M., Schwartz, C.L., Chromatographic separation and purification of secretory IgA from human milk (1977) Prep Biochem, 7, pp. 225-229
Roque-Barreira, M.R., Campos-Nieto, A., Jacalin: An IgA-binding lectin (1985) J Biol Chem, 134, pp. 1740-1743
Kondoh, H., Kobayashi, K., Hagiwara, K., A simple procedure for the isolation of human secretory IgA of IgA1 and IgA2 subclass by a jackfruit lectin, jacalin, affinity chromatography (1987) Mol Immunol, 24, pp. 1219-1222
Bunn-Moreno, M.M., Campos-Neto, A., Lectin(s) extracted from seeds of artocarpus integrifolia (jackfruit): Potent and selective stimulator(s) of distinct human T and B cell functions (1981) J Immunol, 127, pp. 427-430
Nagy, E., Berczi, I., Sehon, A.H., Growth inhibition of murine mammary carcinoma by monoclonal IgE antibodies specific for the mammary tumor virus (1991) Cancer Immunol Immunother, 34, pp. 63-69
Phillips, T.M., More, N.S., Queen, W.D., Thompson, A.M., Isolation and quantitation of serum IgE levels by high-performance immunoaffinity chromatography (1985) J Chromatogr, 327, pp. 205-211
Lehrer, S.B., Isolation of IgE from normal mouse serum (1979) Immunology, 36, pp. 103-109
Ikeyama, S., Nakagawa, S., Arakawa, M., Sugino, H., Kakinuma, A., Purification and characterization of IgE produced by human myeloma cell line, U266 (1986) Mol Immunol, 23, pp. 159-167
Quadri, S.M., Malik, A.B., Tang, X.Z., Patenia, R., Freedman, R.S., Vriesendorp, H.M., Preclinical analysis of intraperitoneal administration of 111In-labeled human tumor reactive monoclonal IgM AC63-2B12 (1995) Cancer Res, 55, pp. 5736-5742
Nevens, J.R., Mallia, A.K., Wendt, M.W., Smith, P.K., Affinity chromatographic purification of immunoglobulin M antibodies utilizing immobilized mannan binding protein (1992) J Chromatogr, 597, pp. 247-253
Polson, A., Von Wechmar, M.B., Van Regenmortel, M.H.V., Isolation of viral IgY antibodies from egg yolks of immunized hens (1980) Immunol Commun, 9, pp. 475-493
Jensenius, J.C., Anderson, I., Hau, J., Crove, M., Koch, C., Eggs: Conveniently packaged antibodies. Methods for purification of yolk IgG (1981) J Immunol Methods, 46, pp. 63-68
Carrol, S.B., Stollar, B.D., Antibodies to calf thymus RNA polymerase II from egg yolks of immunized hens (1983) J Biol Chem, 258, pp. 24-26
Akita, E.M., Nakai, S., Comparison of four purification methods for the production of immunoglobulins from eggs laid by hens immunized with an enteroxigenic E. coli strain (1993) J Immunol Methods, 160, pp. 207-214
Hatta, H., Tsuda, K., Akachi, S., Kim, M., Yamamoto, T., Productivity and some properties of egg yolk antibodies (IgY) against human rotarovirus compared with rabbit IgG (1993) Biosci, Biotechnol, Biochem, 57, pp. 450-454
Gassmann, M., Thommes, P., Weiser, T., Hubscher, U., Efficient production of chicken egg yolk antibodies against a conserved mammalian protein (1990) FASEB J, 4, pp. 2528-2532
Song, C.-S., Yu, J.-H., Bai, D.H., Hester, P.Y., Kim, K.-H., Antibodies to a-subunit of insulin receptor from eggs of immunized hens (1985) J Immunol, 135, pp. 3354-3360
Larsson, A., Sjoquist, J., Chicken IgY: Utilizing the evolutionary difference (1990) Comp Immunol Microbiol Infect Dis, 13, pp. 199-201
Larsson, A., Sjöquist, J., Chicken antibodies: A tool to avoid false positive results by rheumatoid factor in latex fixation tests (1988) J Immunol Methods, 108, pp. 205-208
Kronvall, G., Seal, U.S., Svensson, S., Williams R.C., Jr., Phylogenetic aspects of staphylococcal Protein A-reactive serum globulins in birds and mammals (1974) Acta Pathol Microbiol Scand, Sect B: Microbiol Immunol, 82, pp. 12-18
Shibusawa, Y., Kihira, S., Ito, Y., One-step purification of proteins from chicken egg white using counter-current chromatography (1998) J Chromatogr, B: Biomed Sci Appl, 709, pp. 301-305
Hansen, P., Scoble, J.A., Hanson, B., Hoogenraad, N.J., Isolation and purification of immunoglobulins from chicken eggs using thiophilic interaction chromatography (1998) J Immunol Methods, 215, pp. 1-7
Hatta, H., Kim, M., Yamamoto, T., A novel isolation method for hen egg yolk antibody, "IgY" (1990) Agric Biol Chem, 54, pp. 2531-2535
Polson, A., Isolation of IgY from the yolks of eggs by a chloroform polyethylene glycol procedure (1990) Immunol Invest, 3, pp. 253-258
Polson, A., Coetzer, T., Kruger, J., Von Maltzahn, E., Van der Merwe, K.J., Improvements in the isolation of IgY from the yolks of eggs laid by immunized hens (1985) Immunol Invest, 4, pp. 323-327
Hassl, A., Aspöck, H., Purification of egg yolk immunoglobulins. A two-step procedure using hydrophobic interaction chromatography and gel filtration (1988) J Immunol Methods, 110, pp. 225-228
Porath, J., Belew, M., Thiophilic interaction and the selective adsorption of proteins (1987) Trends Biotechnol, 5, pp. 225-229
Elkak, A., Vjiayalakshmi, M.A., Study of the separation of mouse monoclonal-antibodies by pseudobioaffinity chromatography using matrix-linked histidine and histamine (1991) J Chromatogr, Biomed Appl, 570, pp. 29-41
Ngo, T.T., Khatter, N., Chemistry and preparation of affinity ligands useful in immunoglobulin isolation and serum-protein separation (1990) J Chromatogr, 510, pp. 281-291
Fassina, G., Verdoliva, A., Odierna, M.R., Ruvo, M., Cassani, G., Protein A mimetic peptide ligand for affinity purification of antibodies (1996) J Mol Recognit, 9, pp. 564-569
Houghten, R.A., Pinilla, C., Blondelle, S.E., Appel, J.R., Dooley, C.T., Cuervo, J.H., Generation and use of synthetic peptide combinatorial libraries for basic research and discovery (1991) Nature, 354, pp. 84-86
Lam, K.S., Salmon, S.E., Hersh, E.M., Hruby, V.J., Kazmiersky, W.M., Knapp, R.J., A new type of synthetic peptide library for identifying ligand-binding activity (1991) Nature, 354, pp. 82-84
Fassina, G., Oriented immobilization of peptide ligands on solid supports (1992) J Chromatogr, 591, pp. 99-106
Fournier, A., Couvineau, A., Laburthe, M., Synthesis of a hydrophilic affinity matrix for the purification of the vasoactive intestinal peptide receptor (1993) Anal Biochem, 211, pp. 305-310
Butz, S., Rawer, S., Rapp, W., Birsner, U., Immunization and affinity purification of antibodies using resin-immobilized lysine-branched synthetic peptides (1994) Pept Res, 7, pp. 20-23
Tam, J.P., Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system (1988) Proc Natl Acad Sci U S A, 85, pp. 5409-5413
Ruvo, M., Scardino, P., Cassani, G., Fassina, G., Facile manual synthesis of peptide libraries (1994) Protein Pept Lett, 1, pp. 187-192
Guerrier, L., Flayeuux, I., Schwarz, A., Fassina, G., Boschetti, E., IRIS97: An innovative protein A-peptidomimetic solid phase media for antibody purification (1998) J Mol Recognit, 11, pp. 107-109
Verdoliva, A., Basile, G., Fassina, G., Affinity purification of immunoglobulins from chicken egg yolk using a new synthetic ligand (2000) J Chromatogr, Biomed Appl, 749, pp. 233-242
Marino, M., Ruvo, M., De Falco, S., Fassina, G., Prevention of systemic lupus erythematosus in MRL/lpr mice by administration of an immunoglobulin binding peptide (2000) Nat Biotechnol, 18, pp. 735-739
Palombo, G., Verdoliva, A., Fassina, G., Affinity purification of IgM using a novel synthetic ligand (1998) J Chromatogr, Biomed Appl, 715, pp. 137-145
Palombo, G., De Falco, S., Tortora, M., Cassani, G., Fassina, G., A synthetic ligand for IgA affinity purification (1998) J Mol Recognit, 11, pp. 243-246
Palombo, G., Rossi, M., Cassani, G., Fassina, G., Affinity purification of mouse monoclonal IgE using a protein A mimetic ligand [TG 19318] immobilized on solid supports (1998) J Mol Recognit, 11, pp. 247-249
Fassina, G., Scardino, P., Ruvo, M., Fucile, P., Amodeo, P., Cassani, G., Synthesis of conformationally constrained dimeric peptide libraries (1995) Peptides 1994, pp. 489-490. , Maia H, editor. Leiden: ESCOM
Marino, M., Campanile, N., Ippolito, A., Scarallo, A., Ruvo, M., Fassina, G., Structurally constrained selective ligands for mouse immunoglobulins (1999) Peptides 98, pp. 776-777. , Bajusz S, Hudecz F, editors. Budapest: Academia Kiado
Li, R., Dowd, V., Steward, D.J., Burton, S.J., Lowe, C.R., Design, synthesis, and application of a protein A mimetic (1998) Nat Biotechnol, 16, pp. 190-195
Apter, F. M., Lencer, W. I., Finkelstein, R. A., Mekalanos, J. J., Neutra, M. R., Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro (1993) Infect Immun, 61, pp. 5271-5278
Waldam, R. H., Mach, J. P., Stella, M. M., Rowe, D. S., Secretory IgA in human serum (1970) J Immunol, 105, pp. 43-47
Roque-Barreira, M. R., Campos-Nieto, A., Jacalin: An IgA-binding lectin (1985) J Biol Chem, 134, pp. 1740-1743
Bunn-Moreno, M. M., Campos-Neto, A., Lectin (s) extracted from seeds of artocarpus integrifolia (jackfruit): Potent and selective stimulator (s) of distinct human T and B cell functions (1981) J Immunol, 127, pp. 427-430
Phillips, T. M., More, N. S., Queen, W. D., Thompson, A. M., Isolation and quantitation of serum IgE levels by high-performance immunoaffinity chromatography (1985) J Chromatogr, 327, pp. 205-211
Lehrer, S. B., Isolation of IgE from normal mouse serum (1979) Immunology, 36, pp. 103-109
Quadri, S. M., Malik, A. B., Tang, X. Z., Patenia, R., Freedman, R. S., Vriesendorp, H. M., Preclinical analysis of intraperitoneal administration of 111In-labeled human tumor reactive monoclonal IgM AC63-2B12 (1995) Cancer Res, 55, pp. 5736-5742
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Novel ligands for the affinity-chromatographic purification of antibodies
Affinity chromatography represents one of the most powerful fractionation techniques for the large-scale purification of biotechnological products. Despite its potential, the use of this methodology is limited by the availability of specific ligands for each target. Combinatorial chemistry and molecular modeling, often combined, have become interesting and innovative methods for generating novel ligands, tailored to specific biotechnological needs. One of the greatest area of application has been the discovery of novel ligands for the purification of antibodies, which represent an emerging but very important class of innovative therapeutic agents for the treatment of a vast array of diseases. Naturally available affinity ligands, such as Protein A or G for IgG purification or lectins for IgA and IgM purification, which are obtained from microorganisms or genetically modified bacteria through complex and expensive procedures, are not well suited for large-scale purification and require moreover time-consuming analytical controls to check for the presence of contaminants which may affect the safety of the purified antibody for clinical purposes. Recent results suggest that the application of combinatorial technologies and molecular modeling for the discovery of synthetic ligands may open new avenues for the development of more efficient, less expensive and - more importantly - safer procedures for antibody purification at the industrial level. © 2001 Elsevier Science B.V. All rights reserved.
Affinity chromatography represents one of the most powerful fractionation techniques for the large-scale purification of biotechnological products. Despite its potential, the use of this methodology is limited by the availability of specific ligands for each target. Combinatorial chemistry and molecular modeling, often combined, have become interesting and innovative methods for generating novel ligands, tailored to specific biotechnological needs. One of the greatest area of application has been the discovery of novel ligands for the purification of antibodies, which represent an emerging but very important class of innovative therapeutic agents for the treatment of a vast array of diseases. Naturally available affinity ligands, such as Protein A or G for IgG purification or lectins for IgA and IgM purification, which are obtained from microorganisms or genetically modified bacteria through complex and expensive procedures, are not well suited for large-scale purification and require moreover time-consuming analytical controls to check for the presence of contaminants which may affect the safety of the purified antibody for clinical purposes. Recent results suggest that the application of combinatorial technologies and molecular modeling for the discovery of synthetic ligands may open new avenues for the development of more efficient, less expensive and - more importantly - safer procedures for antibody purification at the industrial level. © 2001 Elsevier Science B.V. All rights reserved.
Novel ligands for the affinity-chromatographic purification of antibodies
Novel ligands for the affinity-chromatographic purification of antibodies
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Impact Factor: 2.564
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (451 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Carriero MV, Franco P, Del Vecchio S, Massa O, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies (500 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1994 Oct 15; 54(20): 5445-5454.
Impact Factor: 8.426
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
CYTOSINE-ARABINOSIDE INCREASES THE BINDING OF I-125 LABELED EPIDERMAL GROWTH-FACTOR AND I-125 TRANSFERRIN AND ENHANCES THE IN-VITRO TARGETING OF HUMAN TUMOR-CELLS WITH ANTI-(GROWTH FACTOR-RECEPTOR) MAB (327 views)
Cancer Immunol Immunother (ISSN: 0340-7004, 0340-7004linking), 1993 Sep; 37(3): 150-156.
Impact Factor: 1.269
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (236 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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D'Aiuto G, Del Vecchio S, Mansi L, D'Aprile M, Botti G, Salvatore M
Malignant melanoma of the nipple: A case studied with radiolabeled monoclonal antibody (623 views)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 1991 Oct 31; 77(5): 449-451.
Impact Factor: 0.408
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Manna R, Salvatore M, Di Leo MA, Scuderi F, Greco AV, Ghirlanda G, Gambassi G
Relationship between urinary neopterin excretion and islet cell antibodies in type 1 (insulin-dependent) diabetes (432 views)
Diabetes Res (ISSN: 0265-5985), 1991 May; 17(1): 33-36.
Impact Factor: 0
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Camera L, Del Vecchio S, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Evaluation of therapeutic response using iodine-131-B72. 3 monoclonal antibody in patients with ovarian carcinoma (463 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991 Apr; 18(4): 269-273.
Impact Factor: 2.692
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Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (411 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1991; 18(1): 85-87.
Impact Factor: 1.042
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Del Vecchio S, Mansi L, Petrillo A, Camera L, Sofia M, Marra A, Carratú L, Salvatore M
Endobronchial administration of iodine-131 B72. 3 monoclonal antibody in patients with lung cancer (294 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991; 18(2): 129-132.
Impact Factor: 2.692
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Papa V, Reese CC, Brunetti A, Vigneri R, Siiteri PK, Goldfine ID
Progestins increase insulin receptor content and insulin stimulation of growth in human breast carcinoma cells (442 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1990 Dec 15; 50(24): 7858-7862.
Impact Factor: 8.426
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Valenza V, Maussier ML, D'Errico G, Lemmo GF, Frontera D, Ferrante A, Saletnich I, Valli A, Quarantelli M
Cancer of the pancreas and the periampullary region: The usefulness of tumor marker products with the monoclonal antibody technique (292 views)
J Nucl Med Allied Sci (ISSN: 0392-0208), 1990 Oct; 34(4SUPPL.): 131-134.
Impact Factor: 1.91
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Del Vecchio S, Reynolds JC
NONUNIFORM DISTRIBUTION OF RADIOLABELED MONOCLONAL-ANTIBODY IN TUMOR (270 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1990 Jul; 31(7): 1252-1252.
Impact Factor: 3.491
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Steis RG, Carrasquillo JA, Mccabe R, Bookman MA, Reynolds JC, Larson SM, Smith JW, Clark JW, Dailey V, Del Vecchio S
Toxicity, immunogenicity, and tumor radioimmunodetecting ability of two human monoclonal antibodies in patients with metastatic colorectal carcinoma (318 views)
J Clin Oncol (ISSN: 0732-183x, 0732-183xlinking), 1990 Mar; 8(3): 476-490.
Impact Factor: 7.878
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Trischitta V, Wong KY, Brunetti A, Scalisi R, Vigneri R, Goldfine ID
Endocytosis, recycling, and degradation of the insulin receptor. Studies with monoclonal antireceptor antibodies that do not activate receptor kinase (316 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 1989 Mar 25; 264(9): 5041-5046.
Impact Factor: 6.963
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d'Onofrio G, Menichella G, Zini G, Rumi C, Pierelli L, Quarantelli M, Puggioni PL, Mango G
Lymphocyte subset counting by immunoperoxidase using an automated routine hematologic analyzer (403 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1989 Mar; 74(2): 137-142.
Impact Factor: 2.56
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Reynolds JC, Del Vecchio S, Sakahara H, Lora ME, Carrasquillo JA, Neumann RD, Larson SM
ANTI-MURINE ANTIBODY RESPONSE TO MOUSE MONOCLONAL ANTIBODIES CLINICAL FINDINGS AND IMPLICATIONS (675 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1989; 16(2): 121-125.
Impact Factor: 1.042
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Salvatore M, Lastoria S, Del Vecchio S, Mansi L
Detection of colon cancer with radiolabelled monoclonal antibodies (301 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1989; 16(2): 103-104.
Impact Factor: 1.042
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Del Vecchio S, Reynolds JC, Carrasquillo JA, Blasberg RG, Neumann RD, Lotze MT, Bryant GJ, Farkas RJ, Larson SM
Local distribution and concentration of intravenously injected 131I-9. 2. 27 monoclonal antibody in human malignant melanoma (350 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1989; 49(10): 2783-2789.
Impact Factor: 8.426
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Manna R, Salvatore M, Scuderi F, Papa G, Marietti G, Greco AV, Ghirlanda G, Gambassi G
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis (318 views)
Diabetes Res (ISSN: 0265-5985), 1988 Nov; 9(3): 101-103.
Impact Factor: 0
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Del Vecchio S, Reynolds JC, Blasberg RG, Neumann RD, Carrasquillo JA, Hellström I, Larson SM
Measurement of local Mr 97, 000 and 250, 000 protein antigen concentration in sections of human melanoma tumor using in vitro quantitative autoradiography (528 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1988; 48(19): 5475-5481.
Impact Factor: 8.426
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* A structure-based approach for the development of a bicyclic peptide acting as a miniaturized anti-CD55 antibody (38 views) (PDF 4 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2021 May 17; 182: 1455-1462.
Impact Factor: 6.95
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Sivaccumar JP, Leonardi A, Iaccarino E, Corvino G, Sanguigno L, Chambery A, Russo R, Valletta M, Latino D, Capasso D, Doti N, Ruvo M, Sandomenico A
* Development of a New Highly Selective Monoclonal Antibody against Preferentially Expressed Antigen in Melanoma (PRAME) and Identification of the Target Epitope by Bio-Layer Interferometry (17 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2021 Mar 20; 22(6): N/D-N/D.
Impact Factor: 4.556
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Sivaccumar J, Sandomenico A, Vitagliano L, Ruvo M
* Monoclonal Antibodies: A Prospective and Retrospective View (71 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2021; 28(3): 435-471.
Impact Factor: 4.184
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Tornatore L, Capece D, Sandomenico A, Verzella D, Vecchiotti D, Zazzeroni F, Ruvo M, Franzoso G
* The Screening of Combinatorial Peptide Libraries for Targeting Key Molecules or Protein-Protein Interactions in the NF-κB Pathway (9 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2366: 343-356.
Impact Factor: 1.17
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Canassa-deleo T, Campo VL, Rodrigues LC, Marchiori MF, Fuzo C, Brigido MM, Sandomenico A, Ruvo M, Maranhao AQ, Dias-baruffi M
* Multifaceted antibodies development against synthetic alpha-dystroglycan mucin glycopeptide as promising tools for dystroglycanopathies diagnostic (157 views)
Glycoconj J (ISSN: 0282-0080linking), 2020 Feb; 37(1): 77-93.
Impact Factor: 2.197
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Di Stasi R, De Rosa L, Diana D, Fattorusso R, D'Andrea LD
* Human Recombinant VEGFR2D4 Biochemical Characterization to Investigate Novel Anti-VEGFR2D4 Antibodies for Allosteric Targeting of VEGFR2 (287 views)
Mol Biotechnol (ISSN: 1073-6085linking, 1559-0305electronic), 2019 Apr 26; 61(7): 513-520.
Impact Factor: 2.275
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Foca G, Iaccarino E, Foca A, Sanguigno L, Untiveros G, Cuevas-nunez M, Strizzi L, Leonardi A, Ruvo M, Sandomenico A
* Development of conformational antibodies targeting Cripto-1 with neutralizing effects in vitro (537 views)
Biochimie (ISSN: 0300-9084linking, 1638-6183electronic), 2019 Mar; 158: 246-256.
Impact Factor: 3.787
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Supuran CT, Alterio V, Di Fiore A, D'Ambrosio K, Carta F, Monti SM, De Simone G
* Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one (568 views)
Med Res Rev (ISSN: 1098-1128electronic, 0198-6325linking), 2018 Sep; 38(6): 1799-1836.
Impact Factor: 8.29
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Fusco FA, Fiorentino G, Pedone E, Contursi P, Bartolucci S, Limauro D
* Biochemical characterization of a novel thermostable beta-glucosidase from Dictyoglomus turgidum (1313 views)
Int J Biol Macromol (ISSN: 1879-0003electronic, 0141-8130linking), 2018 Jul 1; 113: 783-791.
Impact Factor: 4.784
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Calvanese L, Foca A, Sandomenico A, Foca G, Caporale A, Doti N, Iaccarino E, Leonardi A, D'Auria G, Ruvo M, Falcigno L
* Structural insights into the interaction of a monoclonal antibody and Nodal peptides by STD-NMR spectroscopy (499 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2017 Dec 15; 25(24): 6589-6596.
Impact Factor: 2.881
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Maglio O, Costanzo S, Cercola R, Zambrano G, Mauro M, Battaglia R, Ferrini G, Nastri F, Pavone V, Lombardi A
* A Quartz Crystal Microbalance Immunosensor for Stem Cell Selection and Extraction (1099 views) (PDF 151 views)
Sensors (ISSN: 1424-8220, 1424-3210, 1424-8220linking), 2017 Nov 28; 17(12): N/D-N/D.
Impact Factor: 2.475
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Leiria Campo V, Riul TB, Oliveira Bortot L, Martins-teixeira MB, Fiori Marchiori M, Iaccarino E, Ruvo M, Dias-baruffi M, Carvalho I
* A Synthetic MUC1 Glycopeptide Bearing betaGalNAc-Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells (1304 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-4227linking), 2017 Mar 16; 18(6): 527-538.
Impact Factor: 2.774
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Sandomenico A, Focà A, Sanguigno L, Caporale A, Focà G, Pignalosa A, Corvino G, Caragnano A, Beltrami AP, Antoniali G, Tell G, Leonardi A, Ruvo M
* Monoclonal antibodies against pools of mono- and polyacetylated peptides selectively recognize acetylated lysines within the context of the original antigen (391 views) (PDF 219 views)
Mabs-Austin (ISSN: 1942-0862), 2016 Aug; 8: 1575-1589.
Impact Factor: 4.881
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Quero G, Consales M, Severino R, Vaiano P, Boniello A, Sandomenico A, Ruvo M, Borriello A, Diodato L, Zuppolini S, Giordano M, Nettore IC, Mazzarella C, Colao A, Macchia PE, Santorelli F, Cutolo A, Cusano A
* Long period fiber grating nano-optrode for cancer biomarker detection (309 views) (PDF 203 views)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2016 Feb 13; 80: 590-600.
Impact Factor: 7.78
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Sandomenico A, Leonardi A, Berisio R, Sanguigno L, Foca G, Foca A, Ruggiero A, Doti N, Muscariello L, Barone D, Farina C, Owsianka A, Vitagliano L, Patel AH, Ruvo M
* Generation and characterization of monoclonal antibodies against a cyclic variant of Hepatitis C Virus E2 epitope 412-422 (454 views) (PDF 201 views)
J Virol (ISSN: 0022-538x, 0022-538xlinking), 2016 Jan 27; 90(7): 3745-3759.
Impact Factor: 4.663
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Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J
* Human IgG1 antibodies suppress angiogenesis in a target-independent manner (557 views)
Signal Transduct Target Ther (ISSN: 2059-3635print), 2016; 1: N/D-N/D.
Impact Factor: 0
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Palladino P, Aura AM, Spoto G
* Surface plasmon resonance for the label-free detection of Alzheimer's β-amyloid peptide aggregation (528 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2016; 408(3): 849-854.
Impact Factor: 3.431
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Foca A, Sanguigno L, Foca G, Strizzi L, Iannitti R, Palumbo R, Hendrix MJ, Leonardi A, Ruvo M, Sandomenico A
* New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding (725 views) (PDF 265 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2015 Sep 7; 16(9): 21342-21362.
Impact Factor: 3.257
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Klauzinska M, Bertolette D, Tippireddy S, Strizzi L, Gray PC, Gonzales M, Duroux M, Ruvo M, Wechselberger C, Castro NP, Rangel MC, Focà A, Sandomenico A, Hendrix MJC, Salomon D, Cuttitta F
* Cripto-1: an extracellular protein – connecting the sequestered biological dots (296 views)
Connect Tissue Res (ISSN: 0300-8207), 2015; N/D: N/D-N/D.
Impact Factor: 1.411
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Lanzillo R, Liuzzi R, Vallefuoco L, Moccia M, Amato L, Vacca G, Vacchiano V, Portella G, Brescia Morra V
* JC virus antibody index in natalizumab-treated patients: correlations with John Cunningham virus DNA and C-reactive protein level (329 views)
Ther Clin Risk Manag (ISSN: 1178-203x), 2014 Oct 9; 10: 807-814.
Impact Factor: 1.469
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Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (546 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
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Lanzillo R, Bonavita S, Quarantelli M, Vacca G, Lus G, Amato L, Carotenuto A, Tedeschi G, Orefice G, Brescia Morra V
* Natalizumab is effective in multiple sclerosis patients switching from other disease modifying therapies in clinical practice (319 views)
Neurol Sci (ISSN: 1590-1874, 1590-0187, 1590-3478), 2013 Apr; 34(4): 521-528.
Impact Factor: 0.38
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Calce E, Monfregola L, Sandomenico A, Saviano M, De Luca S
* Fluorescence study for selecting specific ligands toward HER2 receptor: An example of receptor fragment approach (483 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2013 Mar; 61: 116-121.
Impact Factor: 3.432
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Rosa R, Marciano R, Malapelle U, Formisano L, Nappi L, D'Amato C, D'Amato V, Damiano V, Marf G, Del Vecchio S, Zannetti A, Greco A, De Stefano A, Carlomagno C, Veneziani BM, Troncone G, De Placido S, Bianco R
* Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models (673 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2013 Jan 1; 19(1): 138-147.
Impact Factor: 8.193
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Lanzillo R, Quarantelli M, Bonavita S, Ventrella G, Lus G, Vacca G, Prinster A, Orefice G, Tedeschi G, Brescia Morra V
* Natalizumab vs interferon beta 1a in relapsing-remitting multiple sclerosis: A head-to-head retrospective study (402 views)
Acta Neurol Scand (ISSN: 0001-6314, 1600-0404), 2012 Nov; 126(5): 306-314.
Impact Factor: 2.474
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Tagliamonte M, Marasco D, Ruggiero A, de Stradis A, Tornesello ML, Totrov M, Buonaguro FM, Buonaguro L
* HIV p24 as Scaffold for Presenting Conformational HIV Env Antigens (468 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2012 Sep 17; 7(8): N/D-N/D.
Impact Factor: 3.73
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Risitano AM, Imbriaco M, Marando L, Seneca E, Soscia E, Malcovati L, Iori AP, Pane F, Notaro R, Matarazzo M
* From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging (360 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2012 Sep; 158(3): 415-418.
Impact Factor: 4.942
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Pedicini P, Caivano R, Jereczek-Fossa BA, Strigari L, Vischioni B, Alterio D, Cremonesi M, Botta F, Nappi A, Improta G, Storto G, Benassi M, Orecchia R
* Modelling the correlation between EGFr expression and tumour cell radiosensitivity, and combined treatments of radiation and monoclonal antibody EGFr inhibitors (385 views)
Theor Biol Med Model (ISSN: 1742-4682), 2012 Jun 19; 9(1): 23-23.
Impact Factor: 1.461
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Zaccaro L, Garcia-lopez Mt Gonzalez-muniz RG
* TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach (461 views)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2011 Jun 15; 21(12): 3541-3545.
Impact Factor: 2.554
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Ruvo M, Sandomenico A, Tudisco L, De Falco S
* Branched peptides for the modulation of protein-protein interactions: More arms are better than one? (532 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2011 Jun; 18(16): 2429-2437.
Impact Factor: 4.859
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (504 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
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Troise F, Monti M, Merlino A, Cozzolino F, Fedele C, Russo Krauss I, Sica F, Pucci P, D'Alessio G, De Lorenzo C
* A novel ErbB2 epitope targeted by human antitumor immunoagents (403 views)
Febs Journal (ISSN: 1742-464x), 2011 Apr; 278(7): 1156-1166.
Impact Factor: 3.79
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Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (314 views) (PDF 221 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
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Palmieri C, Falcone C, Iaccino E, Tuccillo FM, Gaspari M, Trimboli F, De Laurentiis A, Luberto L, Pontoriero M, Pisano A, Vecchio E, Fierro O, Panico M, Larobina M, Gargiulo S, Costa N, Dal Piaz F, Schiavone M, Arra C, Giudice A, Palma G, Barbieri A, Quinto I, Scala G
* In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder (615 views)
Blood (ISSN: 0006-4971, 0006-6497, 0390-6078), 2010 Jul 15; 116(2): 226-238.
Impact Factor: 10.558
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (581 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
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Ponticelli S, Marasco D, Tarallo V, Albuquerque RJC, Mitola S, Takeda A, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S
* Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor (615 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Dec 5; 283(49): 34250-34259.
Impact Factor: 5.52
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Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (562 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (417 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (495 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
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Palmieri G, Marino M, Salvatore M, Budillon A, Meo G, Caraglia M, Montella L
* Cetuximab is an active treatment of metastatic and chemorefractory thymoma (373 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2007 Jan 1; 12(2): 757-761.
Impact Factor: 2.989
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Verdoliva A, Marasco D, De Capua A, Saporito A, Bellofiore P, Manfredi V, Fattorusso R, Pedone C, Ruvo M
* A new ligand for immunoglobulin G subdomains by screening of a synthetic peptide library (501 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2005 Jul; 6(7): 1242-1253.
Impact Factor: 3.94
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (536 views)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Zaccaro L, Bucci E, Vitale RM, Perretta G, Fattorusso R, Benedetti E, Saviano M, Pedone C
* Synthetic peptides mimicking the interleukin-6/gp130 interaction: A two-helix bundle system. Design and confirmational studies (472 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2003; 9(2): 90-105.
Impact Factor: 1.377
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Rossi M, Manfredi V, Ruvo M, Fassina G, Verdoliva A
* Sequence-simplification and chimeric assembly: New models of peptide antigen modification (385 views)
Mol Immunol (ISSN: 0161-5890), 2002 Nov; 39(7-8): 443-451.
Impact Factor: 2.414
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Marino M, Rossi M, Ruvo M, Fassina G
* Novel molecular targets for systemic lupus erythematosus (399 views)
Curr Drug Targets (ISSN: 1389-4501), 2002 Jun; 3(3): 223-228.
Impact Factor: 3.597
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Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (326 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
Impact Factor: 1.623
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Monti SM, Fogliano V, Randazzo G, Peluso G, Logrieco A, Ritieni A
Polyclonal antibodies against fusaproliferin (317 views)
Can J Microbiol (ISSN: 0008-4166), 1999 Jan; 45(1): 45-50.
Impact Factor: 1.072
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (394 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Renda A, Iovino F, Capasso L, Ricciardelli L, Tammaro V, Acampa W
Radioimmunoguided surgery in colorectal cancer: A 6-year experience with four different technical solutions (317 views)
Semin Surg Oncol Wiley Liss Inc (ISSN: 8756-0437), 1998 Dec; 15(4): 226-230.
Impact Factor: 1.045
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Pace L, Catalano L, Pinto A, De Renzo A, Di Gennaro F, Califano C, Del Vecchio S, Rotoli B, Salvatore M
Different patterns of technetium-99m sestamibi uptake in multiple myeloma (366 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1998 Jul; 25(7): 714-720.
Impact Factor: 2.564
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Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (451 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Carriero MV, Franco P, Del Vecchio S, Massa O, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies (500 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1994 Oct 15; 54(20): 5445-5454.
Impact Factor: 8.426
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
CYTOSINE-ARABINOSIDE INCREASES THE BINDING OF I-125 LABELED EPIDERMAL GROWTH-FACTOR AND I-125 TRANSFERRIN AND ENHANCES THE IN-VITRO TARGETING OF HUMAN TUMOR-CELLS WITH ANTI-(GROWTH FACTOR-RECEPTOR) MAB (327 views)
Cancer Immunol Immunother (ISSN: 0340-7004, 0340-7004linking), 1993 Sep; 37(3): 150-156.
Impact Factor: 1.269
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (236 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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D'Aiuto G, Del Vecchio S, Mansi L, D'Aprile M, Botti G, Salvatore M
Malignant melanoma of the nipple: A case studied with radiolabeled monoclonal antibody (623 views)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 1991 Oct 31; 77(5): 449-451.
Impact Factor: 0.408
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Manna R, Salvatore M, Di Leo MA, Scuderi F, Greco AV, Ghirlanda G, Gambassi G
Relationship between urinary neopterin excretion and islet cell antibodies in type 1 (insulin-dependent) diabetes (432 views)
Diabetes Res (ISSN: 0265-5985), 1991 May; 17(1): 33-36.
Impact Factor: 0
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Camera L, Del Vecchio S, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Evaluation of therapeutic response using iodine-131-B72. 3 monoclonal antibody in patients with ovarian carcinoma (463 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991 Apr; 18(4): 269-273.
Impact Factor: 2.692
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Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (411 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1991; 18(1): 85-87.
Impact Factor: 1.042
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Del Vecchio S, Mansi L, Petrillo A, Camera L, Sofia M, Marra A, Carratú L, Salvatore M
Endobronchial administration of iodine-131 B72. 3 monoclonal antibody in patients with lung cancer (294 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991; 18(2): 129-132.
Impact Factor: 2.692
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Papa V, Reese CC, Brunetti A, Vigneri R, Siiteri PK, Goldfine ID
Progestins increase insulin receptor content and insulin stimulation of growth in human breast carcinoma cells (442 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1990 Dec 15; 50(24): 7858-7862.
Impact Factor: 8.426
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Valenza V, Maussier ML, D'Errico G, Lemmo GF, Frontera D, Ferrante A, Saletnich I, Valli A, Quarantelli M
Cancer of the pancreas and the periampullary region: The usefulness of tumor marker products with the monoclonal antibody technique (292 views)
J Nucl Med Allied Sci (ISSN: 0392-0208), 1990 Oct; 34(4SUPPL.): 131-134.
Impact Factor: 1.91
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Del Vecchio S, Reynolds JC
NONUNIFORM DISTRIBUTION OF RADIOLABELED MONOCLONAL-ANTIBODY IN TUMOR (270 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1990 Jul; 31(7): 1252-1252.
Impact Factor: 3.491
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Steis RG, Carrasquillo JA, Mccabe R, Bookman MA, Reynolds JC, Larson SM, Smith JW, Clark JW, Dailey V, Del Vecchio S
Toxicity, immunogenicity, and tumor radioimmunodetecting ability of two human monoclonal antibodies in patients with metastatic colorectal carcinoma (318 views)
J Clin Oncol (ISSN: 0732-183x, 0732-183xlinking), 1990 Mar; 8(3): 476-490.
Impact Factor: 7.878
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Trischitta V, Wong KY, Brunetti A, Scalisi R, Vigneri R, Goldfine ID
Endocytosis, recycling, and degradation of the insulin receptor. Studies with monoclonal antireceptor antibodies that do not activate receptor kinase (316 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 1989 Mar 25; 264(9): 5041-5046.
Impact Factor: 6.963
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d'Onofrio G, Menichella G, Zini G, Rumi C, Pierelli L, Quarantelli M, Puggioni PL, Mango G
Lymphocyte subset counting by immunoperoxidase using an automated routine hematologic analyzer (403 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1989 Mar; 74(2): 137-142.
Impact Factor: 2.56
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Reynolds JC, Del Vecchio S, Sakahara H, Lora ME, Carrasquillo JA, Neumann RD, Larson SM
ANTI-MURINE ANTIBODY RESPONSE TO MOUSE MONOCLONAL ANTIBODIES CLINICAL FINDINGS AND IMPLICATIONS (675 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1989; 16(2): 121-125.
Impact Factor: 1.042
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Salvatore M, Lastoria S, Del Vecchio S, Mansi L
Detection of colon cancer with radiolabelled monoclonal antibodies (301 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1989; 16(2): 103-104.
Impact Factor: 1.042
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Del Vecchio S, Reynolds JC, Carrasquillo JA, Blasberg RG, Neumann RD, Lotze MT, Bryant GJ, Farkas RJ, Larson SM
Local distribution and concentration of intravenously injected 131I-9. 2. 27 monoclonal antibody in human malignant melanoma (350 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1989; 49(10): 2783-2789.
Impact Factor: 8.426
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Manna R, Salvatore M, Scuderi F, Papa G, Marietti G, Greco AV, Ghirlanda G, Gambassi G
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis (318 views)
Diabetes Res (ISSN: 0265-5985), 1988 Nov; 9(3): 101-103.
Impact Factor: 0
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Del Vecchio S, Reynolds JC, Blasberg RG, Neumann RD, Carrasquillo JA, Hellström I, Larson SM
Measurement of local Mr 97, 000 and 250, 000 protein antigen concentration in sections of human melanoma tumor using in vitro quantitative autoradiography (528 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1988; 48(19): 5475-5481.
Impact Factor: 8.426
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72 Records (69 excluding Abstracts).
Total impact factor: 256.056 (247.374 excluding Abstracts).
Total 5 year impact factor: 269.812 (258.516 excluding Abstracts).
Total impact factor: 256.056 (247.374 excluding Abstracts).
Total 5 year impact factor: 269.812 (258.516 excluding Abstracts).
1313 views. Last view on Wednesday 31 May 2023, 18:44:36
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