Functionalized gold nanoparticles for ultrasensitive DNA detection
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Functionalized gold nanoparticles for ultrasensitive DNA detection (822 views)

Zanoli LM, D'Agata R, Spoto G

Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.

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Paper type: Journal Article,

Impact factor: 3.659, 5-year impact factor: 3.756

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84858709248&partnerID=40&md5=d93930cdc7d9d9347ed207b9ac2b8f7a

Keywords: Dna Detection, Electrochemical Detection, Gold Nanoparticles, Optical Detection, Pcr-Free, Qcm, Scanometric Detection, Metal Nanoparticles, Polymerase Chain Reaction, Biotin, Silver, Chemistry, Colorimetry, Electrochemistry, Genetic Procedures, Methodology, Quartz Crystal Microbalance, Review, Sensitivity And Specificity, Surface Plasmon Resonance, Biosensing Techniques, Quartz Crystal Microbalance Techniques,

Affiliations:
*** IBB - CNR ***

Scuola Superiore di Catania, C/o Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, 95125 Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, 95125 Catania, Italy


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Functionalized gold nanoparticles for ultrasensitive DNA detection

A major challenge in the area of DNA detection is the development of rapid methods that do not require polymerase chain reaction (PCR) amplification of the genetic sample. The PCR amplification step increases the cost of the assay, the complexity of the detection, and the quantity of DNA required for the assay. In this context, methods that are able to perform DNA analyses with ultrasensitivity have recently been investigated with the aim of developing new PCR-free detection protocols. Functionalized gold nanoparticles have played a central role in the development of such methods. Here, possibilities offered by functionalized gold nanoparticle in the ultrasensitive detection of DNA are discussed. The different functionalization protocols available for gold nanoparticles and the principal DNA detection methods that are able to detect DNA at the femtomolar to attomolar level are presented.
Functionalized gold nanoparticles for ultrasensitive DNA detection

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Functionalized gold nanoparticles for ultrasensitive DNA detection

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Zambrano G, Ruggiero E, Malafronte A, Chino M, Maglio O, Pavone V, Nastri F, Lombardi A
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Satriano C, Munzone A, Cucci LM, Giacomelli C, Trincavelli ML, Martini C, Rizzarelli E, La Mendola D
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Merlino A, Caterino M, Russo Krauss I, Vergara A
* Missing gold atoms in lysozyme crystals used to grow gold nanoparticles (602 views)
Nat Nanotechnol (ISSN: 1748-3387), 2015; 10(4): 285-285.
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Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (699 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
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D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (646 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
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Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L
* Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting (1027 views)
Bioconjug Chem (ISSN: 1520-4812, 1043-1802, 1520-4812electronic), 2012 Mar 21; 23(3): 340-349.
Impact Factor: 4.58
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (908 views)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (792 views)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Impact Factor: 5.361
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D'Urso L, Grasso G, Messina E, Bongiorno C, Scuderi V, Scalese S, Puglisi O, Spoto G, Compagnini G
* The Role of Linear Carbon Chains in the Aggregation of Copper, Silver, and Gold Nanoparticles (854 views)
J Phys Chem C (ISSN: 1932-7447), 2010 Jan 21; 114(2): 907-915.
Impact Factor: 4.524
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Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (631 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
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10 Records (10 excluding Abstracts).
Total impact factor: 63.254 (63.254 excluding Abstracts).
Total 5 year impact factor: 68.091 (68.091 excluding Abstracts).

Last modified by Marco Comerci on Sunday 12 July 2020, 13:14:57
822 views. Last view on Friday 25 April 2025, 9:24:37