Keywords: Biosensors, Dna Detection, Gold Nanoparticles, Pcr-Free, Surface Plasmon Resonance Imaging, Assay Development, Direct Detection, Nucleic Acid Detection, Signal Enhancement, State Of The Art, Chemical Detection, Fluorophores, Polymerase Chain Reaction, Animal, Chemistry, Evaluation, Genetic Procedures, Human, Methodology, Molecular Imaging, Review, Biosensing Techniques,
Affiliations: *** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania 95125, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania 95125, Italy
Istituto Nazionale di Biostrutture e Biosistemi, Catania 95125, Italy
References: Not available.
Surface plasmon resonance imaging for nucleic acid detection
Surface plasmon resonance imaging (SPRI) is a powerful tool for simple, fast and cheap nucleic acid detection. Great efforts have been made during the last decade with the aim of developing even more sensitive and specific SPRI-based methods to be used for the direct detection of DNA and RNA. Here, after a description of the fundamentals of SPRI, the state of the art of recent platform and assay developments is presented, with special attention given to advances in SPRI signal enhancement procedures.
Surface plasmon resonance imaging for nucleic acid detection