Structural and functional insights into IkappaB-alpha/HIV-1 Tat interaction (694 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Sep; 93(9): 1592-1600.
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Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 3.022, 5-year impact factor: 3.424
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-79960846480&partnerID=40&md5=a69d887b29132674c8d07d8aef36c95c
Keywords: Cd Spectroscopy, Luciferase Assay, Surface Plasmon Resonance, Human Immunodeficiency Virus Proteinase, I Kappa B Alpha, Transactivator Protein, Article, Binding Affinity, Chemical Mutagenesis, Circular Dichroism, Hela Cell, Human Cell, Immunoprecipitation, In Vitro Study, Molecular Recognition, Nonhuman, Protein Binding, Protein Expression, Protein Folding, Protein Immobilization, Protein Protein Interaction, Protein Synthesis, Western Blotting, Amino Acid Sequence, Binding Sites, Cell Nucleus, Hiv-1, I-Kappa B Proteins, Kinetics, Molecular Sequence Data, Nf-Kappa B, Structure-Activity Relationship, Tat Gene Products, Metabolism, Chemistry,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, CNR, Via Mezzocannone 16, 80134 Naples, Italy.
Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Viale Europa-Germaneto, 88100 Catanzaro, Italy
Department of Biological Sciences, University Federico II of Naples, Via Mezzocannone 16, 80134 Naples, Italy
Department of Biochemistry and Medical Biotechnology, University Federico II of Naples, Via Sergio Pansini 5, 80131 Naples, Italy
References:
Not available.
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Sep; 93(9): 1592-1600.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 3.022, 5-year impact factor: 3.424
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-79960846480&partnerID=40&md5=a69d887b29132674c8d07d8aef36c95c
Keywords: Cd Spectroscopy, Luciferase Assay, Surface Plasmon Resonance, Human Immunodeficiency Virus Proteinase, I Kappa B Alpha, Transactivator Protein, Article, Binding Affinity, Chemical Mutagenesis, Circular Dichroism, Hela Cell, Human Cell, Immunoprecipitation, In Vitro Study, Molecular Recognition, Nonhuman, Protein Binding, Protein Expression, Protein Folding, Protein Immobilization, Protein Protein Interaction, Protein Synthesis, Western Blotting, Amino Acid Sequence, Binding Sites, Cell Nucleus, Hiv-1, I-Kappa B Proteins, Kinetics, Molecular Sequence Data, Nf-Kappa B, Structure-Activity Relationship, Tat Gene Products, Metabolism, Chemistry,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, CNR, Via Mezzocannone 16, 80134 Naples, Italy.
Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Viale Europa-Germaneto, 88100 Catanzaro, Italy
Department of Biological Sciences, University Federico II of Naples, Via Mezzocannone 16, 80134 Naples, Italy
Department of Biochemistry and Medical Biotechnology, University Federico II of Naples, Via Sergio Pansini 5, 80131 Naples, Italy
References:
Not available.
Structural and functional insights into IkappaB-alpha/HIV-1 Tat interaction
Protein protein interactions play fundamental roles in physiological and pathological biological processes. The characterization of the structural determinants of protein-protein recognition represents an important step for the development of molecular entities able to modulate these interactions. We have recently found that I kappa B-alpha (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) blocks the HIV-1 expression and replication in a NF-kappa B-independent manner by directly binding to the virus-encoded Tat transactivator. Here, we report the evaluation of the entity of binding of I kappa B-alpha to Tat through in vitro Surface Plasmon Resonance assay. Moreover, by designing and characterizing a set of peptides of the C-terminus region of I kappa B-alpha, we show that the peptide corresponding to the I kappa B-alpha sequence 262-287 was able to bind to Tat with high affinity (300 nM). The characterization of a number of I kappa B-alpha-based peptides also provided insights into their intrinsic folding properties. These findings have been corroborated by mutagenesis studies on the full-length I kappa B-alpha, which unveil that different I kappa B-alpha residues are involved in NF-kappa B or Tat recognition. (C) 2011 Elsevier Masson SAS. All rights reserved.
Protein protein interactions play fundamental roles in physiological and pathological biological processes. The characterization of the structural determinants of protein-protein recognition represents an important step for the development of molecular entities able to modulate these interactions. We have recently found that I kappa B-alpha (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) blocks the HIV-1 expression and replication in a NF-kappa B-independent manner by directly binding to the virus-encoded Tat transactivator. Here, we report the evaluation of the entity of binding of I kappa B-alpha to Tat through in vitro Surface Plasmon Resonance assay. Moreover, by designing and characterizing a set of peptides of the C-terminus region of I kappa B-alpha, we show that the peptide corresponding to the I kappa B-alpha sequence 262-287 was able to bind to Tat with high affinity (300 nM). The characterization of a number of I kappa B-alpha-based peptides also provided insights into their intrinsic folding properties. These findings have been corroborated by mutagenesis studies on the full-length I kappa B-alpha, which unveil that different I kappa B-alpha residues are involved in NF-kappa B or Tat recognition. (C) 2011 Elsevier Masson SAS. All rights reserved.
Structural and functional insights into IkappaB-alpha/HIV-1 Tat interaction
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Structural and functional insights into IkappaB-alpha/HIV-1 Tat interaction
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Sandomenico A, Monti SM, Marasco D, Dathan N, Palumbo R, Saviano M, Ruvo M
* Ige-Binding Properties And Selectivity Of Peptide Mimics Of The Fcvarepsilonri Binding Site (1728 views)
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Grasso G, D'Agata R, Zanoli L, Spoto G
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Grasso G, Bush AI, D'Agata R, Rizzarelli E, Spoto G
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Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
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Gioia M, Monaco S, Van Den Steen PE, Sbardella D, Grasso G, Marini S, Overall CM, Opdenakker G, Coletta M
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Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
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D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
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Grasso G, Rizzarelli E, Spoto G
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Impact Factor: 2.233
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
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Rossi M, Ruvo M, Marasco D, Colombo M, Cassani G, Verdoliva A
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Zanoli L, Dagata R, Spoto G
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Impact Factor: 0.1
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Sorriento D, Ciccarelli M, Santulli G, Campanile A, Altobelli GG, Cimini V, Galasso G, Astone D, Piscione F, Pastore L, Trimarco B, Iaccarino G
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Grasso G, Fragai M, Rizzarelli E, Spoto G, Yeo KJ
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Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
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Grasso G, Fragai M, Rizzarelli E, Spoto G, Yeo KJ
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Marasco D, Saporito A, Ponticelli S, Chambery A, De Falco S, Pedone C, Minchiotti G, Ruvo M
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D'Agata R, Grasso G, Iacono G, Spoto G, Vecchio G
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Grasso G, D'Agata R, Rizzarelli E, Spoto G, D'Andrea LD, Pedone C, Picardi A, Romanelli A, Fragai M, Yeo KJ
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Arena G, Contino A, D'Agata R, Sgarlata C, Spoto G
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Zell R, Sidigi K, Bucci E, Stelzner A, Goerlach M
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* Novel insights on nucleopeptide binding: a spectroscopic and in silico investigation on the interaction of a thymine-bearing tetrapeptide with a homoadenine DNA (183 views)
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Riccardi C, Capasso D, Coppola A, Platella C, Montesarchio D, Di Gaetano S, Roviello GN, Musumeci D
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D’errico S, Falanga AP, Capasso D, Di Gaetano S, Marzano M, Terracciano M, Roviello GN, Piccialli G, Oliviero G, Borbone N
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De Luca S, Verdoliva V, Saviano M, Fattorusso R, Diana D
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Riccardi C, Capasso D, Rozza GM, Platella C, Montesarchio D, Di Gaetano S, Marzo T, Pratesi A, Messori L, Roviello GN, Musumeci D
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Ferrucci V, De Antonellis P, Pennino FP, Asadzadeh F, Virgilio A, Montanaro D, Galeone A, Boffa I, Pisano I, Scognamiglio I, Navas L, Diana D, Pedone E, Gargiulo S, Gramanzini M, Brunetti A, Danielson L, Carotenuto M, Liguori L, Verrico A, Quaglietta L, Errico ME, Del Monaco V, D'Argenio V, Tirone F, Mastronuzzi A, Donofrio V, Giangaspero F, Picard D, Remke M, Garzia L, Daniels C, Delattre O, Swartling FJ, Weiss WA, Salvatore F, Fattorusso R, Chesler L, Taylor MD, Cinalli G, Zollo M
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La Manna S, Scognamiglio PL, Di Natale C, Leone M, Mercurio FA, Malfitano AM, Cianfarani F, Madonna S, Caravella S, Albanesi C, Novellino E, Marasco D
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Impact Factor: 3.188
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Leiria Campo V, Riul TB, Oliveira Bortot L, Martins-teixeira MB, Fiori Marchiori M, Iaccarino E, Ruvo M, Dias-baruffi M, Carvalho I
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Scognamiglio PL, Di Natale C, Leone M, Cascella R, Cecchi C, Lirussi L, Antoniali G, Riccardi D, Morelli G, Tell G, Chiti F, Marasco D
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Impact Factor: 5.168
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Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
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Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
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Impact Factor: 3.108
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Palladino P, Aura AM, Spoto G
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Anal Bioanal Chem (ISSN: 1618-2642), 2016; 408(3): 849-854.
Impact Factor: 3.431
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Foca A, Sanguigno L, Foca G, Strizzi L, Iannitti R, Palumbo R, Hendrix MJ, Leonardi A, Ruvo M, Sandomenico A
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Impact Factor: 3.257
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Calvanese L, Sandomenico A, Caporale A, Foca A, Foca G, D'Auria G, Falcigno L, Ruvo M
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Impact Factor: 1.951
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GrassoG, Satriano C, Milardi D
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Impact Factor: 2.363
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Lanza V, D'Agata R, Iacono G, Bellia F, Spoto G, Vecchio G
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Impact Factor: 3.205
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Falcigno L, D'Auria G, Calvanese L, Marasco D, Iacobelli R, Scognamiglio PL, Brun P, Danesin R, Pasqualin M, Castagliuolo I, Dettin M
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Marasco D, Messori L, Marzo T, Merlino A
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Impact Factor: 4.177
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Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (645 views)
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Impact Factor: 2.85
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Altieri F, Di Stadio CS, Severino V, Sandomenico A, Minopoli G, Miselli G, Di Maro A, Ruvo M, Chambery A, Quagliariello V, Masullo M, Rippa E, Arcari P
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Impact Factor: 2.963
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Calvanese L, Falcigno L, Maglione C, Marasco D, Ruggiero A, Squeglia F, Berisio R, D'Auria G
* Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (766 views)
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Impact Factor: 2.385
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Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D
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Impact Factor: 5.353
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Roviello GN, Musumeci D, D'Alessandro C, Pedone C
* Binding ability of a thymine-functionalized oligolysine towards nucleic acids (401 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2014 Feb 1; 22(3): 997-1002.
Impact Factor: 2.793
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Romanucci V, Milardi D, Campagna T, Gaglione M, Messere A, D'Urso A, Crisafi E, La Rosa C, Zarrelli A, Balzarini J, Di Fabio G
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Impact Factor: 2.793
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Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S
* Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (883 views)
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Impact Factor: 5.48
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Correale S, Esposito C, Pirone L, Vitagliano L, Di Gaetano S, Pedone E
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Impact Factor: 2.337
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Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M
* Peptide-Lipid Interactions: Experiments and Applications (1391 views)
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Impact Factor: 2.339
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Sandomenico A, Severino V, Chambery A, Focà A, Focà G, Farina C, Ruvo M
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Impact Factor: 2.275
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Stelitano V, Brandt A, Fernicola S, Franceschini S, Giardina G, Pica A, Rinaldo S, Sica F, Cutruzzola F
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Impact Factor: 4.188
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Grasso G, Spoto G
* Plasmonics for the study of metal ion-protein interactions (569 views)
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Impact Factor: 3.578
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Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M
* Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights (507 views)
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Impact Factor: 2.92
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Causa F, Della Moglie R, Iaccino E, Mimmi S, Marasco D, Scognamiglio PL, Battista E, Palmieri C, Cosenza C, Sanguigno L, Quinto I, Scala G, Netti PA
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Impact Factor: 1.646
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D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (440 views)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
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D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (680 views)
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Impact Factor: 0
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Mercurio FA, Marasco D, Pirone L, Pedone E, Pellecchia M, Leone M
* Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor (586 views)
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Impact Factor: 3.377
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Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (540 views)
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Impact Factor: 3.659
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Pilla P, Sandomenico A, Malachovsk V, Borriello A, Giordano M, Cutolo A, Ruvo M, Cusano A
* A protein-based biointerfacing route toward label-free immunoassays with long period gratings in transition mode (633 views)
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Impact Factor: 5.437
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
* GSM48878: CD8 IL2-D2 (444 views)
Gene Expression Omnibus, 2011 Dec 2; 59(2): 302-308.
Impact Factor: 2.082
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D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D
* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (812 views)
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Impact Factor: 3.99
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D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R
* Direct Detection of Point Mutations in Nonamplified Human Genomic DNA (891 views)
Analytical Chemistry (ISSN: 0003-2700), 2011 Nov 15; 83(22): 8711-8717.
Impact Factor: 5.856
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Esposito C, Marasco D, Delogu G, Pedone E, Berisio R
* Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation (474 views)
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Impact Factor: 2.484
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (595 views)
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Impact Factor: 2.282
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Ciccarelli M, Sorriento D, Cipolletta E, Santulli G, Fusco A, Zhou R-H, Eckhart AD, Peppel K, Koch WJ, Trimarco B, Iaccarino G
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Impact Factor: 4.409
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Fantini D, Vascotto C, Marasco D, D'Ambrosio C, Romanello M, Vitagliano L, Pedone C, Poletto M, Cesaratto L, Quadrifoglio F, Scaloni A, Radicella JP, Tell G
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Impact Factor: 7.836
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Calvanese L, Marasco D, Doti N, Saporito A, D'Auria G, Paolillo L, Ruvo M, Falcigno L
* Structural Investigations on the Nodal-Cripto Binding: A Theoretical and Experimental Approach (653 views)
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Impact Factor: 2.572
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Palmieri C, Falcone C, Iaccino E, Tuccillo FM, Gaspari M, Trimboli F, De Laurentiis A, Luberto L, Pontoriero M, Pisano A, Vecchio E, Fierro O, Panico M, Larobina M, Gargiulo S, Costa N, Dal Piaz F, Schiavone M, Arra C, Giudice A, Palma G, Barbieri A, Quinto I, Scala G
* In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder (762 views)
Blood (ISSN: 0006-4971, 0006-6497, 0390-6078), 2010 Jul 15; 116(2): 226-238.
Impact Factor: 10.558
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Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C, Galdiero M
* The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein (633 views)
Jbc Papers (ISSN: 1083-351x, 0021-9258, 0021-9258linking), 2010 May 28; 285(22): 17123-17136.
Impact Factor: 5.328
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (591 views)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
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D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (643 views)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Impact Factor: 5.361
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Galdiero S, Falanga A, Vitiello G, Vitiello M, Pedone C, D'Errico G, Galdiero M
* Role of membranotropic sequences from herpes simplex virus type I glycoproteins B and H in the fusion process (679 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0005-2736, 0925-4439), 2010 Mar; 1798(3): 579-591.
Impact Factor: 4.647
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D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (352 views)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
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Sorriento D, Iaccarino G, Trimarco B
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy (839 views)
High Blood Press Cardiovasc Prev High Blood Pressure And Cardiovascular Prevention (ISSN: 1120-9879), 2010; 17(4): 209-217.
Impact Factor: 0
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Sandomenico A, Monti SM, Marasco D, Dathan N, Palumbo R, Saviano M, Ruvo M
* Ige-Binding Properties And Selectivity Of Peptide Mimics Of The Fcvarepsilonri Binding Site (1728 views)
Mol Immunol (ISSN: 0161-5890), 2009 Oct; 46(16): 3300-3309.
Impact Factor: 3.202
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Grasso G, D'Agata R, Zanoli L, Spoto G
* Microfluidic networks for surface plasmon resonance imaging real-time kinetics experiments (343 views)
Microchemical Journal (ISSN: 0026-265x), 2009 Sep; 93(1): 82-86.
Impact Factor: 2.579
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Grasso G, Bush AI, D'Agata R, Rizzarelli E, Spoto G
* Enzyme solid-state support assays: a surface plasmon resonance and mass spectrometry coupled study of immobilized insulin degrading enzyme (780 views)
Eur Biophys J (ISSN: 1432-1017, 0175-7571, 0175-7571linking), 2009 Apr; 38(4): 407-414.
Impact Factor: 2.437
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Ciaccio C, Tundo GR, Grasso G, Spoto G, Marasco D, Ruvo M, Gioia M, Rizzarelli E, Coletta M
* Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity (568 views)
J Mol Biol (ISSN: 1089-8638, 0022-2836, 1089-8638electronic), 2009 Feb 6; 385(5): 1556-1567.
Impact Factor: 3.871
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Gioia M, Monaco S, Van Den Steen PE, Sbardella D, Grasso G, Marini S, Overall CM, Opdenakker G, Coletta M
* The Collagen Binding Domain of Gelatinase A Modulates Degradation of Collagen IV by Gelatinase (507 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009; 386(2): 419-434.
Impact Factor: 3.871
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Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (539 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
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D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (489 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
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Grasso G, Rizzarelli E, Spoto G
* How the binding and degrading capabilities of insulin degrading enzyme are affected by ubiquitin (444 views)
Bba-Gen Subjects (ISSN: 0006-3002, 1570-9639, 0925-4439), 2008 Jul; 1784(7-8): 1122-1126.
Impact Factor: 2.233
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Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
* Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (551 views)
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Impact Factor: 1.621
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Rossi M, Ruvo M, Marasco D, Colombo M, Cassani G, Verdoliva A
* Anti-allergic properties of a new all-D synthetic immunoglobulin-binding peptide (513 views)
Mol Immunol (ISSN: 0161-5890), 2008 Jan; 45(1): 226-234.
Impact Factor: 3.555
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Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (390 views)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
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Sorriento D, Ciccarelli M, Santulli G, Campanile A, Altobelli GG, Cimini V, Galasso G, Astone D, Piscione F, Pastore L, Trimarco B, Iaccarino G
* The G-protein-coupled receptor kinase 5 inhibits NFκB transcriptional activity by inducing nuclear accumulation of IκBα (641 views)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2008; 105(46): 17818-17823.
Impact Factor: 9.38
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Grasso G, Fragai M, Rizzarelli E, Spoto G, Yeo KJ
* A new methodology for monitoring the activity of cdMMP-12 anchored and freeze-dried on Au (111) (485 views)
Journal Of The American Society For Mass Spectrometry (ISSN: 1044-0305), 2007 May; 18(5): 961-969.
Impact Factor: 3.664
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Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
* Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments (733 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.
Impact Factor: 3.354
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Grasso G, Fragai M, Rizzarelli E, Spoto G, Yeo KJ
* In situ AP/MALDI-MS characterization of anchored matrix metalloproteinases (602 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2006 Dec; 41(12): 1561-1569.
Impact Factor: 2.945
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Marasco D, Saporito A, Ponticelli S, Chambery A, De Falco S, Pedone C, Minchiotti G, Ruvo M
* Chemical synthesis of mouse Cripto CFC variants (443 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Sep 15; 64(3): 779-788.
Impact Factor: 3.73
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D'Agata R, Grasso G, Iacono G, Spoto G, Vecchio G
* Lectin recognition of a new SOD mimic bioconjugate studied with surface plasmon resonance imaging (378 views)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2006 Feb 21; 4(4): 610-612.
Impact Factor: 2.874
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Grasso G, D'Agata R, Rizzarelli E, Spoto G, D'Andrea LD, Pedone C, Picardi A, Romanelli A, Fragai M, Yeo KJ
* Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au(111) surfaces monitored by ESI-MS (705 views)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2005 Dec; 40(12): 1565-1571.
Impact Factor: 3.574
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Arena G, Contino A, D'Agata R, Sgarlata C, Spoto G
* Ordered anchored cavities at work: A new and rapid SPR-based method for the detection of trace amounts of Cs+ (477 views)
New J Chem (ISSN: 1144-0546), 2005; 29(11): 1393-1395.
Impact Factor: 2.574
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Zell R, Sidigi K, Bucci E, Stelzner A, Goerlach M
* Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C (557 views)
Rna (ISSN: 1355-8382), 2002; 8(2): 188-201.
Impact Factor: 5.099
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72 Records (69 excluding Abstracts).
Total impact factor: 257.792 (251.79 excluding Abstracts).
Total 5 year impact factor: 256.412 (247.43 excluding Abstracts).
Total impact factor: 257.792 (251.79 excluding Abstracts).
Total 5 year impact factor: 256.412 (247.43 excluding Abstracts).
694 views. Last view on Tuesday 24 September 2024, 13:56:53
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