Sleep disordered breathing and airway disease in primary ciliary dyskinesia (690 views)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2014 May; 19(4): 570-575.
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Paper type: Journal Article,
Impact factor: 3.345, 5-year impact factor: 2.65
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84899055901&partnerID=40&md5=99f595b4130fd6b73cddbc27214ceb7f
Keywords: Lower Airway, Obstructive Sleep Apnoea Syndrome, Primary Ciliary Dyskinesia, Sleep-Disordered Breathing, Upper Airway, Adenoid Hypertrophy, Adolescent, Apnea Hypopnea Index, Article, Bronchiectasis, Chronic Rhinosinusitis, Clinical Article, Controlled Study, Cross-Sectional Study, Disease Severity, Endoscopy, Forced Expiratory Volume, Forced Vital Capacity, Functional Residual Capacity, High Resolution Computer Tomography, Human, Lung Function Test, Mother, Nasal Endoscopy, Oxygen Desaturation, Oxygen Saturation, Polysomnography, Priority Journal, Prospective Study, Rating Scale, Respiratory Polysomnography, Respiratory Tract Disease, Scoring System, Sleep Disordered Breathing, Sleep Disturbances Scale For Children, Sleep Quality, Somnolence, Adult, Consumer Health Information, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Epidemiology, Kartagener Syndrome, Complications, Diagnosis, Physiopathology, Education, Psychology, Methods, Prospective Studies, Respiratory Function Tests, Risk Assessment, Risk Factors, Severity Of Illness Index, Sleep Apnea Syndromes, Etiology, X-Ray Computed, Attitude To Health, Computer Assisted Tomography, Pathophysiology, Procedures,
Affiliations:
*** IBB - CNR ***
Department of Translational Medical Sciences, Reproductive and Odontostomatologic Sciences, Unit of Ear, Nose and Throat and Molecular and Cellular Biology and Pathology, Federico II University, Via Sergio Pansini, 5-80131 Naples, Italy
Department of Neurosciences, Reproductive and Odontostomatologic Sciences, Unit of Ear, Nose and Throat and Molecular and Cellular Biology and Pathology, Federico II University, Naples, Italy
Biostructure and Bioimaging Institute, National Research Council, Naples, Italy
Clinic of Child and Adolescent Neuropsychiatry, Department of Mental and Physical Health, and Preventive Medicine, Second University of Naples, Naples, Italy
References:
Not available.
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2014 May; 19(4): 570-575.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.345, 5-year impact factor: 2.65
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84899055901&partnerID=40&md5=99f595b4130fd6b73cddbc27214ceb7f
Keywords: Lower Airway, Obstructive Sleep Apnoea Syndrome, Primary Ciliary Dyskinesia, Sleep-Disordered Breathing, Upper Airway, Adenoid Hypertrophy, Adolescent, Apnea Hypopnea Index, Article, Bronchiectasis, Chronic Rhinosinusitis, Clinical Article, Controlled Study, Cross-Sectional Study, Disease Severity, Endoscopy, Forced Expiratory Volume, Forced Vital Capacity, Functional Residual Capacity, High Resolution Computer Tomography, Human, Lung Function Test, Mother, Nasal Endoscopy, Oxygen Desaturation, Oxygen Saturation, Polysomnography, Priority Journal, Prospective Study, Rating Scale, Respiratory Polysomnography, Respiratory Tract Disease, Scoring System, Sleep Disordered Breathing, Sleep Disturbances Scale For Children, Sleep Quality, Somnolence, Adult, Consumer Health Information, Cross-Sectional Studies, Female, Health Knowledge, Attitudes, Practice, Epidemiology, Kartagener Syndrome, Complications, Diagnosis, Physiopathology, Education, Psychology, Methods, Prospective Studies, Respiratory Function Tests, Risk Assessment, Risk Factors, Severity Of Illness Index, Sleep Apnea Syndromes, Etiology, X-Ray Computed, Attitude To Health, Computer Assisted Tomography, Pathophysiology, Procedures,
Affiliations:
*** IBB - CNR ***
Department of Translational Medical Sciences, Reproductive and Odontostomatologic Sciences, Unit of Ear, Nose and Throat and Molecular and Cellular Biology and Pathology, Federico II University, Via Sergio Pansini, 5-80131 Naples, Italy
Department of Neurosciences, Reproductive and Odontostomatologic Sciences, Unit of Ear, Nose and Throat and Molecular and Cellular Biology and Pathology, Federico II University, Naples, Italy
Biostructure and Bioimaging Institute, National Research Council, Naples, Italy
Clinic of Child and Adolescent Neuropsychiatry, Department of Mental and Physical Health, and Preventive Medicine, Second University of Naples, Naples, Italy
References:
Not available.
Sleep disordered breathing and airway disease in primary ciliary dyskinesia
Background and objective Sleep-disordered breathing (SDB) may develop in primary ciliary dyskinesia (PCD), leading to these diseases worsening one another. Methods Sixteen stable PCD patients (4. 9-17. 2 years) and 42 controls underwent overnight respiratory polysomnography (rPSG) and Sleep Disturbances Scale for Children (SDSC). In PCD we assessed nasal endoscopy, pulmonary function tests and chest high-resolution computed tomography (HRCT). Results Compared with controls, PCD had higher obstructive apnoea (4. 7 vs 0. 2, P < 0. 001), central apnoea (0. 8 vs 0. 2, P < 0. 001), hypopnoea (1. 8 vs 0. 2, P < 0. 001), apnoea-hypopnoea (7. 8 vs 0. 6, P < 0. 001), oxygen desaturation indexes (ODI; 0. 7 vs 0. 2, P = 0. 002), and mean oxygen desaturation (4% vs 1%, P < 0. 001), while mean and nadir oxygen saturation (97. 1% vs 98. 1, P < 0. 001) (93% vs 97. 2%, P < 0. 001) were lower, respectively. In PCD, SDSC was unrelated to rPSG (P > 0. 05), with total score and subscores of disorders in initiating and maintaining sleep, and sleep-wake transition lower than controls. PCD patients had chronic rhinosinusitis (100%) and adenoidal hypertrophy (50%). Total HRCT score was 7 (range 0-14). ODI correlated with functional residual capacity (r = 0. 8, P = 0. 02), total HRCT (r = 0. 6, P = 0. 03) and peribronchial thickening scores (r = 0. 7, P = 0. 02). Oxygen saturation was associated with bronchiectasis severity score (r = -0. 6, P = 0. 02). Conclusions PCD's parents may underestimate SDB. As nocturnal desaturation is associated with lung function and structure abnormalities, SDB may significantly contribute to pulmonary morbidity. 2014 The Authors. Respirology 2014 Asian Pacific Society of Respirology
Background and objective Sleep-disordered breathing (SDB) may develop in primary ciliary dyskinesia (PCD), leading to these diseases worsening one another. Methods Sixteen stable PCD patients (4. 9-17. 2 years) and 42 controls underwent overnight respiratory polysomnography (rPSG) and Sleep Disturbances Scale for Children (SDSC). In PCD we assessed nasal endoscopy, pulmonary function tests and chest high-resolution computed tomography (HRCT). Results Compared with controls, PCD had higher obstructive apnoea (4. 7 vs 0. 2, P < 0. 001), central apnoea (0. 8 vs 0. 2, P < 0. 001), hypopnoea (1. 8 vs 0. 2, P < 0. 001), apnoea-hypopnoea (7. 8 vs 0. 6, P < 0. 001), oxygen desaturation indexes (ODI; 0. 7 vs 0. 2, P = 0. 002), and mean oxygen desaturation (4% vs 1%, P < 0. 001), while mean and nadir oxygen saturation (97. 1% vs 98. 1, P < 0. 001) (93% vs 97. 2%, P < 0. 001) were lower, respectively. In PCD, SDSC was unrelated to rPSG (P > 0. 05), with total score and subscores of disorders in initiating and maintaining sleep, and sleep-wake transition lower than controls. PCD patients had chronic rhinosinusitis (100%) and adenoidal hypertrophy (50%). Total HRCT score was 7 (range 0-14). ODI correlated with functional residual capacity (r = 0. 8, P = 0. 02), total HRCT (r = 0. 6, P = 0. 03) and peribronchial thickening scores (r = 0. 7, P = 0. 02). Oxygen saturation was associated with bronchiectasis severity score (r = -0. 6, P = 0. 02). Conclusions PCD's parents may underestimate SDB. As nocturnal desaturation is associated with lung function and structure abnormalities, SDB may significantly contribute to pulmonary morbidity. 2014 The Authors. Respirology 2014 Asian Pacific Society of Respirology
Sleep disordered breathing and airway disease in primary ciliary dyskinesia
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Sleep disordered breathing and airway disease in primary ciliary dyskinesia
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Maglione M, Montella S, Mollica C, Carnovale V, Iacotucci P, De Gregorio F, Tosco A, Cervasio M, Raia V, Santamaria F
* Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study (2170 views)
Ital J Pediatr (ISSN: 1720-8424, 1824-7288), 2017 Apr; 43(1): 34-34.
Impact Factor: 1.776
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Maglione M, Bush A, Montella S, Mollica C, Manna A, Esposito A, Santamaria F
* Progression of lung disease in primary ciliary dyskinesia: Is spirometry less accurate than CT? (591 views)
Pediatr Pulmonol (ISSN: 8755-6863), 2012 May; 47(5): 498-504.
Impact Factor: 2.375
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Montella S, Maglione M, Bruzzese D, Mollica C, Pignata C, Aloj G, Manna A, Esposito A, Mirra V, Santamaria F
* Magnetic resonance imaging is an accurate and reliable method to evaluate non-cystic fibrosis paediatric lung disease (668 views)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2012 Jan; 17(1): 87-91.
Impact Factor: 2.781
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Montella S, Santamaria F, Salvatore M, Maglione M, Iacotucci P, De Santi MM, Mollica C
* Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings (573 views)
Ital J Pediatr (ISSN: 1824-7288, 1720-8424), 2009 Sep 6; 35(24): 24-24.
Impact Factor: 0.722
View Export to BibTeX Export to EndNote
* Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study (2170 views)
Ital J Pediatr (ISSN: 1720-8424, 1824-7288), 2017 Apr; 43(1): 34-34.
Impact Factor: 1.776
View Export to BibTeX Export to EndNote
Maglione M, Bush A, Montella S, Mollica C, Manna A, Esposito A, Santamaria F
* Progression of lung disease in primary ciliary dyskinesia: Is spirometry less accurate than CT? (591 views)
Pediatr Pulmonol (ISSN: 8755-6863), 2012 May; 47(5): 498-504.
Impact Factor: 2.375
View Export to BibTeX Export to EndNote
Montella S, Maglione M, Bruzzese D, Mollica C, Pignata C, Aloj G, Manna A, Esposito A, Mirra V, Santamaria F
* Magnetic resonance imaging is an accurate and reliable method to evaluate non-cystic fibrosis paediatric lung disease (668 views)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2012 Jan; 17(1): 87-91.
Impact Factor: 2.781
View Export to BibTeX Export to EndNote
Montella S, Santamaria F, Salvatore M, Maglione M, Iacotucci P, De Santi MM, Mollica C
* Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings (573 views)
Ital J Pediatr (ISSN: 1824-7288, 1720-8424), 2009 Sep 6; 35(24): 24-24.
Impact Factor: 0.722
View Export to BibTeX Export to EndNote
4 Records (2 excluding Abstracts).
Total impact factor: 7.654 (5.156 excluding Abstracts).
Total 5 year impact factor: 6.911 (4.319 excluding Abstracts).
Total impact factor: 7.654 (5.156 excluding Abstracts).
Total 5 year impact factor: 6.911 (4.319 excluding Abstracts).
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