Atypical Clinical And Radiological Presentation Of Cryptococcal Choroid Plexitis In An Immunocompetent Woman (1030 views)
J Neurol Sci (ISSN: 1878-5883, 0022-510x, 0022-510xlinking), 2013 Nov 15; 334(1-2): 180-182.
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Paper type: Journal Article, Case Reports
Impact factor: 1.453, 5-year impact factor: 2.389
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84887470662&partnerID=40&md5=0c1aaad3363277a79fe5b60015ea2b14
Keywords: Behavioral Disturbances, Cryptococcal Choroid Plexitis, Fdg-Pet, Granulomatous Lesions, Immunocompetent Host, Intraventricular Cryptococcoma, Temporal Lobe Epilepsy, Amphotericin B, Fluconazole, Flucytosine, Fluorodeoxyglucose, Lamotrigine, Adult, Amnesia, Anxiety, Apathy, Article, Behavior Change, Behavior Disorder, Brain Edema, Brain Infection, Case Report, Cerebrospinal Fluid Analysis, Cerebrospinal Fluid Culture, Computer Assisted Tomography, Confusion, Cryptococcosis, Cryptococcus Neoformans, Disease Duration, Drug Substitution, Electroencephalogram, Epileptic Aura, Female, Fine Needle Aspiration Biopsy, Glucose Blood Level, Glucose Brain Level, Hospital Admission, Human, Immunocompromised Patient, Latex Agglutination Test, Leukocyte Count, Lung Biopsy, Lung Nodule, Medical History, Neuroimaging, Nonhuman, Nuclear Magnetic Resonance Imaging, Paresthesia, Positron Emission Tomography, Priority Journal, Protein Cerebrospinal Fluid Level, Short Term Memory, Therapy Effect, Thorax Radiography, Treatment Duration, Middle Aged, Choroid Plexus Microbiology, Cryptococcosis Complications Diagnosis Pathology, Edema Complications Pathology, Immunocompetence , Mri
Affiliations:
*** IBB - CNR ***
Department of Neurological Sciences, University Federico II of Naples, Via Sergio Pansini, 5-80131 Naples, Italy
Institute of Biostructure and Bioimaging, CNR, Naples, Italy
Department of Diagnostic Radiology and Radiotherapy, Federico II University of Naples, Italy
References:
Not available.
J Neurol Sci (ISSN: 1878-5883, 0022-510x, 0022-510xlinking), 2013 Nov 15; 334(1-2): 180-182.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Case Reports
Impact factor: 1.453, 5-year impact factor: 2.389
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84887470662&partnerID=40&md5=0c1aaad3363277a79fe5b60015ea2b14
Keywords: Behavioral Disturbances, Cryptococcal Choroid Plexitis, Fdg-Pet, Granulomatous Lesions, Immunocompetent Host, Intraventricular Cryptococcoma, Temporal Lobe Epilepsy, Amphotericin B, Fluconazole, Flucytosine, Fluorodeoxyglucose, Lamotrigine, Adult, Amnesia, Anxiety, Apathy, Article, Behavior Change, Behavior Disorder, Brain Edema, Brain Infection, Case Report, Cerebrospinal Fluid Analysis, Cerebrospinal Fluid Culture, Computer Assisted Tomography, Confusion, Cryptococcosis, Cryptococcus Neoformans, Disease Duration, Drug Substitution, Electroencephalogram, Epileptic Aura, Female, Fine Needle Aspiration Biopsy, Glucose Blood Level, Glucose Brain Level, Hospital Admission, Human, Immunocompromised Patient, Latex Agglutination Test, Leukocyte Count, Lung Biopsy, Lung Nodule, Medical History, Neuroimaging, Nonhuman, Nuclear Magnetic Resonance Imaging, Paresthesia, Positron Emission Tomography, Priority Journal, Protein Cerebrospinal Fluid Level, Short Term Memory, Therapy Effect, Thorax Radiography, Treatment Duration, Middle Aged, Choroid Plexus Microbiology, Cryptococcosis Complications Diagnosis Pathology, Edema Complications Pathology, Immunocompetence , Mri
Affiliations:
*** IBB - CNR ***
Department of Neurological Sciences, University Federico II of Naples, Via Sergio Pansini, 5-80131 Naples, Italy
Institute of Biostructure and Bioimaging, CNR, Naples, Italy
Department of Diagnostic Radiology and Radiotherapy, Federico II University of Naples, Italy
References:
Not available.
Atypical Clinical And Radiological Presentation Of Cryptococcal Choroid Plexitis In An Immunocompetent Woman
Central nervous system cryptococcal infections usually manifests as meningitis, meningoencephalitis, encephalitis or ventriculitis. Cryptococcal choroid plexus inflammation is a particularly rare entity most often presenting with signs and symptoms of intracranial hypertension, hydrocephalus or meningitis due to a delayed diagnosis. Herein we reported the case of a 63-year-old immunocompetent woman with a history of temporal lobe epilepsy and behavioral disorders. Magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomographic (FDG-PET) images revealed atypical cryptococcal choroid plexitis with surrounding bitemporal edema without features of meningitis, intraparenchymal cryptococcoma or hydrocephalus. The patient underwent serial MRI and FDG-PET images performed before and after antifungal therapy that caused a marked clinical improvement. Our case also suggests a potential role of FDG-PET in the monitoring antifungal therapeutic efficacy. (C) 2013 Elsevier B. V. All rights reserved
Central nervous system cryptococcal infections usually manifests as meningitis, meningoencephalitis, encephalitis or ventriculitis. Cryptococcal choroid plexus inflammation is a particularly rare entity most often presenting with signs and symptoms of intracranial hypertension, hydrocephalus or meningitis due to a delayed diagnosis. Herein we reported the case of a 63-year-old immunocompetent woman with a history of temporal lobe epilepsy and behavioral disorders. Magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomographic (FDG-PET) images revealed atypical cryptococcal choroid plexitis with surrounding bitemporal edema without features of meningitis, intraparenchymal cryptococcoma or hydrocephalus. The patient underwent serial MRI and FDG-PET images performed before and after antifungal therapy that caused a marked clinical improvement. Our case also suggests a potential role of FDG-PET in the monitoring antifungal therapeutic efficacy. (C) 2013 Elsevier B. V. All rights reserved
Atypical Clinical And Radiological Presentation Of Cryptococcal Choroid Plexitis In An Immunocompetent Woman
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