Neuroprotective effects of the monoamine oxidase inhibitor Tranylcypromine and its amide derivatives against Abeta(1-42)-induced toxicity(1054 views) Caraci F, Pappalardo G, Basile L, Giuffrida A, Copani A, Tosto R, Sinopoli A, Giuffrida ML, Pirrone E, Drago F, Pignatello R, Guccione S
Keywords: Amyloid, Anti-Aggregant Acstivity, Antidepressants, Butyric Acid (pubchem Cid: 264), Neurons, Neuroprotection, Tranylcypromine (pubchem Cid: 19493 Or 26070), Tranylcypromine Acetamide (pubchem Cid: 583384), Anti-Aggregant Activity, Amyloid Beta Protein[1-42], Glial Fibrillary Acidic Protein, Microtubule Associated Protein 2, Tranylcypromine Butyramide, Tranylcypromine Derivative, Unclassified Drug, Alzheimer Disease, Animal Cell, Animal Experiment, Animal Model, Article, Controlled Study, Drug Degradation, Drug Efficacy, Drug Potency, Drug Stability, Drug Synthesis, In Vitro Study, Nerve Cell Necrosis, Nerve Degeneration, Neurotoxicity, Nonhuman, Priority Journal, Protein Aggregation,
Affiliations: *** IBB - CNR ***
Department of drug Sciences, university of Catania, Catania, Italy; IRCCS Associazione Oasi maria S.S., institute for research on mental Retardation and brain aging, Troina, Italy. Electronic address: Carafil@hotmail.com., National research council, institute of Biostructures and Bioimaging, Catania, Italy., Department of drug Sciences, university of Catania, Catania, Italy., Department of drug Sciences, university of Catania, Catania, Italy; National research council, institute of Biostructures and Bioimaging, Catania, Italy., National research council, institute of Biostructures and Bioimaging, Catania, Italy; PhD Program in Translational Biomedicine, university of Catania., Department of biomedical and Biotechnological Sciences, university of Catania, Catania, Italy.,
References: Not available.
Neuroprotective effects of the monoamine oxidase inhibitor Tranylcypromine and its amide derivatives against Abeta(1-42)-induced toxicity