In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging (348 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 0008-5472linking), 2016 Nov 15; 76(22): 6463-6470.
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Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 9.122, 5-year impact factor: 9.826
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995495851&doi=10.1158%2f0008-5472.CAN-16-0825&partnerID=40&md5=c657aa7ec66ed9025e45421194c3c5cb
Keywords: Acidosis , Humans , Magnetic Resonance Imaging Methods , Neoplasms Metabolism , Positron Emission Tomography Computed Tomography Methods,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging (CNR) c/o Molecular Biotechnologies Center, Torino, Italy., Molecular Imaging Center, University of Torino, Torino, Italy., Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany., Molecular Imaging Center, University of Torino, Torino, Italy. silvio.aime@unito.it.,
Molecular Imaging Center, University of Torino, Torino, Italy.
Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.
Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany.
References:
Not available.
Cancer Res (ISSN: 0008-5472, 1538-7445, 0008-5472linking), 2016 Nov 15; 76(22): 6463-6470.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 9.122, 5-year impact factor: 9.826
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995495851&doi=10.1158%2f0008-5472.CAN-16-0825&partnerID=40&md5=c657aa7ec66ed9025e45421194c3c5cb
Keywords: Acidosis , Humans , Magnetic Resonance Imaging Methods , Neoplasms Metabolism , Positron Emission Tomography Computed Tomography Methods,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging (CNR) c/o Molecular Biotechnologies Center, Torino, Italy., Molecular Imaging Center, University of Torino, Torino, Italy., Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany., Molecular Imaging Center, University of Torino, Torino, Italy. silvio.aime@unito.it.,
Molecular Imaging Center, University of Torino, Torino, Italy.
Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.
Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany.
References:
Not available.
In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging
The vast majority of cancers exhibit increased glucose uptake and glycolysis regardless of oxygen availability. This metabolic shift leads to an enhanced production of lactic acid that decreases extracellular pH (pHe), a hallmark of the tumor microenvironment. In this way, dysregulated tumor pHe and upregulated glucose metabolism are linked tightly and their relative assessment may be useful to gain understanding of the underlying biology. Here we investigated noninvasively the in vivo correlation between tumor (18)F-FDG uptake and extracellular pH values in a murine model of HER2(+) breast cancer. Tumor extracellular pH and perfusion were assessed by acquiring MRI-CEST (chemical exchange saturation transfer) images on a 3T scanner after intravenous administration of a pH-responsive contrast agent (iopamidol). Static PET images were recorded immediately after MRI acquisitions to quantify the extent of (18)F-FDG uptake. We demonstrated the occurrence of tumor pHe changes that report on acidification of the interstitial fluid caused by an accelerated glycolysis. Combined PET and MRI-CEST images reported complementary spatial information of the altered glucose metabolism. Notably, a significant inverse correlation was found between extracellular tumor pH and (18)F-FDG uptake, as a high (18)F-FDG uptake corresponds to lower extracellular pH values. These results show how merging the information from (18)F-FDG-uptake and extracellular pH measurements can improve characterization of the tumor microenvironment. Cancer Res; 76(22); 6463-70. ©2016 AACR.
The vast majority of cancers exhibit increased glucose uptake and glycolysis regardless of oxygen availability. This metabolic shift leads to an enhanced production of lactic acid that decreases extracellular pH (pHe), a hallmark of the tumor microenvironment. In this way, dysregulated tumor pHe and upregulated glucose metabolism are linked tightly and their relative assessment may be useful to gain understanding of the underlying biology. Here we investigated noninvasively the in vivo correlation between tumor (18)F-FDG uptake and extracellular pH values in a murine model of HER2(+) breast cancer. Tumor extracellular pH and perfusion were assessed by acquiring MRI-CEST (chemical exchange saturation transfer) images on a 3T scanner after intravenous administration of a pH-responsive contrast agent (iopamidol). Static PET images were recorded immediately after MRI acquisitions to quantify the extent of (18)F-FDG uptake. We demonstrated the occurrence of tumor pHe changes that report on acidification of the interstitial fluid caused by an accelerated glycolysis. Combined PET and MRI-CEST images reported complementary spatial information of the altered glucose metabolism. Notably, a significant inverse correlation was found between extracellular tumor pH and (18)F-FDG uptake, as a high (18)F-FDG uptake corresponds to lower extracellular pH values. These results show how merging the information from (18)F-FDG-uptake and extracellular pH measurements can improve characterization of the tumor microenvironment. Cancer Res; 76(22); 6463-70. ©2016 AACR.
In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging
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In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging
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* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (588 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
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Maruotti GM, Paladini D, Napolitano R, Mazzarelli LL, Russo T, Quarantelli M, D'Armiento MR, Martinelli P
* Prenatal 2D and 3D ultrasound diagnosis of diprosopus: Case report with post-mortem magnetic resonance images (MRI) and review of the literature (702 views)
Prenat Diagn (ISSN: 0197-3851, 0197-3851linking), 2009 Oct; 29(10): 992-994.
Impact Factor: 1.707
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Napolitano R, Maruotti GM, Quarantelli M, Martinelli P, Paladini D
* Prenatal diagnosis of Seckel syndrome on 3-dimensional sonography and magnetic resonance imaging (627 views)
J Ultrasound Med (ISSN: 0278-4297, 1550-9613, 0278-4297linking), 2009 Mar; 28(3): 369-374.
Impact Factor: 1.181
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Digilio G, Catanzaro V, Fedeli F, Gianolio E, Menchise V, Napolitano R, Gringeri C, Aime S
* Targeting exofacial protein thiols with Gd-III complexes. An efficient procedure for MRI cell labelling (423 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2009 Feb 28; (8): 893-895.
Impact Factor: 5.504
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (720 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (815 views) (PDF 283 views)
J Neurol Sci (ISSN: 0022-510x, 0022-510xlinking), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
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De Leva MF, Varrone A, Filla A, Quarantelli M, Bilo L, Piscitelli V, Salvatore E, Ammendola S, Striano S, De Michele G, Bonavita V, Pappata S
* Neuroimaging follow-up in a case of Rasmussen's encephalitis with dyskinesias (568 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2007 Oct 31; 22(14): 2117-2121.
Impact Factor: 3.207
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Imbriaco M, Spinelli L, Cuocolo A, Maurea S, Sica G, Quarantelli M, Pisani A, Liuzzi R, Cianciaruso B, Sabbatini M, Salvatore M
* MRI characterization of myocardial tissue in patients with Fabry's disease (836 views)
Ajr Am J Roentgenol (ISSN: 1546-3141, 0361-803x, 1546-3141electronic), 2007 Mar; 188(3): 850-853.
Impact Factor: 2.47
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Amato U, Larobina M, Antoniadis A, Alfano B
* Segmentation of magnetic resonance brain images through discriminant analysis (787 views) (PDF 274 views)
J Neurosci Methods (ISSN: 0165-0270, 0165-0270linking, 1872-678xelectronic), 2003 Dec 30; 131(1-2): 65-74.
Impact Factor: 1.777
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Quarantelli M, Larobina M, Volpe U, Amati G, Tedeschi E, Ciarmiello A, Brunetti A, Galderisi S, Alfano B
* Stereotaxy-based regional brain volumetry applied to segmented MRI: Validation and results in deficit and nondeficit schizophrenia (676 views) (PDF 248 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 17(1): 373-384.
Impact Factor: 5.624
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Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (861 views) (PDF 628 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1998 Mar; 39(3): 497-499.
Impact Factor: 2.962
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Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (886 views) (PDF 726 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Impact Factor: 3.012
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (386 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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Alfano B, Brunetti A, Ciarmiello A, Salvatore M
Simultaneous display of multiple MR parameters with 'quantitative magnetic color imaging' (643 views) (PDF 663 views)
J Comput Assisted Tomogr (ISSN: 0363-8715), 1992 Jul; 16(4): 634-640.
Impact Factor: 1.263
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* Fully automated measurement of intracranial CSF and brain parenchyma volumes in pediatric hydrocephalus by segmentation of clinical MRI studies (66 views)
Med Phys (ISSN: 0094-2405linking), 2023 Dec; 50 (12 ): 7921-7933.
Impact Factor:
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Longo DL, Carella A, Corrado A, Pirotta E, Mohanta Z, Singh A, Stabinska J, Liu G, Mcmahon MT
* A snapshot of the vast array of diamagnetic CEST MRI contrast agents (146 views)
Nmr Biomed (ISSN: 0952-3480linking, 1099-1492electronic), 2023 Jun; 36(6): e4715-N/D.
Impact Factor: 4.044
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Pirozzi MA, Tranfa M, Tortora M, Lanzillo R, Brescia Morra V, Brunetti A, Alfano B, Quarantelli M
* A polynomial regression-based approach to estimate relaxation rate maps suitable for multiparametric segmentation of clinical brain MRI studies in multiple sclerosis (41 views)
Comput Methods Programs Biomed (ISSN: 0169-2607linking), 2022 Aug; 223: 106957-106957.
Impact Factor:
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Platella C, Gaglione R, Napolitano E, Arciello A, Pirota V, Doria F, Musumeci D, Montesarchio D
* DNA Binding Mode Analysis of a Core-Extended Naphthalene Diimide as a Conformation-Sensitive Fluorescent Probe of G-Quadruplex Structures (191 views)
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Impact Factor: 2.598
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Larobina M, Megna R, Solla R
* Comparison of three freeware software packages for (18)F-FDG PET texture feature calculation (307 views)
Jpn J Radiol (ISSN: 1867-1071linking), 2021 Jul; 39(7): 710-719.
Impact Factor: 1.439
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Mainenti PP, Castiglione F, Rispo A, Laccetti E, Guarino S, Romeo V, Testa A, Pace L, Maurea S
* MR-enterography in Crohn's disease: what MRE mural parameters are associated to one-year therapeutic management outcome? (304 views)
Br J Radiol (ISSN: 0007-1285linking, 1748-880xelectronic), 2021 Feb 1; 94(1118): 20200844-20200844.
Impact Factor: 2.196
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Brancato V, Aiello M, Basso L, Monti S, Palumbo L, Di Costanzo G, Salvatore M, Ragozzino A, Cavaliere C
* Evaluation of a multiparametric MRI radiomic-based approach for stratification of equivocal PI-RADS 3 and upgraded PI-RADS 4 prostatic lesions (271 views)
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2021 Jan 12; 11(1): 643-643.
Impact Factor: 4.379
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Anemone A, Consolino L, Conti L, Irrera P, Hsu MY, Villano D, Dastrù W, Porporato PE, Cavallo F, Longo DL
* Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential (152 views)
Br J Cancer (ISSN: 0007-0920linking, 0007-0920print), 2021 Jan; 124(1): 207-216.
Impact Factor: 5.49
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Zöllner FG, Dastrù W, Irrera P, Longo DL, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR
* Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration (83 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 637-653.
Impact Factor: 1.17
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Kim H, Wu Y, Villano D, Longo DL, Mcmahon MT, Sun PZ
* Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI (440 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 667-688.
Impact Factor: 1.17
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Irrera P, Consolino L, Dastrù W, Pedersen M, Zöllner FG, Longo DL
* Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol (101 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 429-441.
Impact Factor: 1.17
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Pedersen M, Irrera P, Dastrù W, Zöllner FG, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR, Longo DL
* Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts (184 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 205-227.
Impact Factor: 1.17
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Pohlmann A, Back SJ, Fekete A, Friedli I, Hectors S, Jerome NP, Ku MC, Longo DL, Meier M, Millward JM, Periquito JS, Seeliger E, Serai SD, Waiczies S, Sourbron S, Laustsen C, Niendorf T
* Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies (120 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 3-23.
Impact Factor: 1.17
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Longo DL, Irrera P, Consolino L, Sun PZ, Mcmahon MT
* Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST) MRI: Basic Concept (233 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 241-256.
Impact Factor: 1.17
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Pavuluri KD, Consolino L, Longo DL, Irrera P, Sun PZ, Mcmahon MT
* Renal pH Mapping Using Chemical Exchange Saturation Transfer (CEST) MRI: Experimental Protocol (251 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 455-471.
Impact Factor: 1.17
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Cocozza S, Pontillo G, De Michele G, Perillo T, Guerriero E, Ugga L, Salvatore E, Galatolo D, Riso V, Saccà F, Quarantelli M, Brunetti A
* The "crab sign": an imaging feature of spinocerebellar ataxia type 48 (160 views)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2020 Sep; 62(9): 1095-1103.
Impact Factor: 2.238
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Pontillo G, Cocozza S, Di Stasi M, Carotenuto A, Paolella C, Cipullo MB, Perillo T, Vola EA, Russo C, Masullo M, Moccia M, Lanzillo R, Tedeschi E, Elefante A, Brescia Morra V, Brunetti A, Quarantelli M, Petracca M
* 2D linear measures of ventricular enlargement may be relevant markers of brain atrophy and long-term disability progression in multiple sclerosis (288 views)
Eur Radiol (ISSN: 0938-7994linking, 1432-1084electronic), 2020 Jul; 30(7): 3813-3822.
Impact Factor: 4.101
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Tear LR, Carrera C, Gianolio E, Aime S
* Towards an Improved Design of MRI Contrast Agents: Synthesis and Relaxometric Characterisation of Gd-HPDO3A Analogues (239 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2020 May 12; 26(27): 6056-6063.
Impact Factor: 4.857
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Cassiano MT, Lanzillo R, Alfano B, Costabile T, Comerci M, Prinster A, Moccia M, Megna R, Morra VB, Quarantelli M, Brunetti A
* Voxel-based analysis of gray matter relaxation rates shows different correlation patterns for cognitive impairment and physical disability in relapsing-remitting multiple sclerosis (289 views)
Neuroimage Clin (ISSN: 2213-1582linking, 2213-1582electronic), 2020 Jan 30; 26: 102201-102201.
Impact Factor: 2.526
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Romeo V, Ricciardi C, Cuocolo R, Stanzione A, Verde F, Sarno L, Improta G, Mainenti PP, D'Armiento M, Brunetti A, Maurea S
* Machine learning analysis of MRI-derived texture features to predict placenta accreta spectrum in patients with placenta previa (197 views)
Magn Reson Imaging (ISSN: 0730-725xlinking), 2019 Dec; 64: 71-76.
Impact Factor: 2.037
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Romeo V, Sarno L, Volpe A, Ginocchio MI, Esposito R, Mainenti PP, Petretta M, Liuzzi R, D'Armiento M, Martinelli P, Brunetti A, Maurea S
* US and MR imaging findings to detect placental adhesion spectrum (PAS) in patients with placenta previa: a comparative systematic study (173 views)
Abdom Radiol (ISSN: 2366-0058electronic, 2366-004xprint), 2019 Oct; 44(10): 3398-3407.
Impact Factor: 2.147
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De Michele G, Lieto M, Galatolo D, Salvatore E, Cocozza S, Barghigiani M, Tessa A, Baldacci J, Pappata S, Filla A, De Michele G, Santorelli FM
* Spinocerebellar ataxia 48 presenting with ataxia associated with cognitive, psychiatric, and extrapyramidal features: A report of two Italian families (313 views)
Parkinsonism Relat D (ISSN: 1353-8020linking, 1353-8020print), 2019 May 14; 65: 91-96.
Impact Factor: 4.721
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Kujawa A, Kim M, Demetriou E, Anemone A, Livio Longo D, Zaiss M, Golay X
* Assessment of a clinically feasible Bayesian fitting algorithm using a simplified description of Chemical Exchange Saturation Transfer (CEST) imaging (115 views)
J Magn Reson (ISSN: 1090-7807linking), 2019 Mar; 300: 120-134.
Impact Factor: 2.586
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Megna R, Alfano B, Lanzillo R, Costabile T, Comerci M, Vacca G, Carotenuto A, Moccia M, Servillo G, Prinster A, Brescia Morra V, Quarantelli M
* Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment (385 views) (PDF 50 views)
J Neurol (ISSN: 1432-1459electronic, 0340-5354linking, 0340-5354print), 2019 Feb; 266(2): 361-368.
Impact Factor: 3.853
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Cocozza S, Pontillo G, Lanzillo R, Russo C, Petracca M, Di Stasi M, Paolella C, Vola EA, Criscuolo C, Moccia M, Lamberti A, Monti S, Brescia Morra V, Elefante A, Palma G, Tedeschi E, Brunetti A
* MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis (380 views)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2019 Feb; 61(2): 155-162.
Impact Factor: 1.287
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Arotenuto A, Cocozza S, Quarantelli M, Arcara G, Lanzillo R, Brescia Morra V, Cerillo I, Tedeschi E, Orefice G, Bambini V, Brunetti A, Iodice R
* Pragmatic abilities in multiple sclerosis: The contribution of the temporo-parietal junction (722 views)
Brain Lang (ISSN: 0093-934xlinking), 2018 Oct; 185: 47-53.
Impact Factor: 2.851
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Marchitelli R, Aiello M, Cachia A, Quarantelli M, Cavaliere C, Postiglione A, Tedeschi G, Montella P, Milan G, Salvatore M, Salvatore E, Baron JC, Pappata S
* Simultaneous resting-state FDG-PET/fMRI in Alzheimer Disease: Relationship between glucose metabolism and intrinsic activity (1610 views)
Neuroimage (ISSN: 1053-8119linking), 2018 Aug 1; 176: 246-258.
Impact Factor: 5.835
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Ugga L, Romeo V, Tedeschi E, Brunetti A, Quarantelli M
* Superparamagnetic iron oxide nanocolloids in MRI studies of neuroinflammation (782 views)
J Neurosci Methods (ISSN: 0165-0270linking, 1872-678xelectronic), 2018 Jun 18; 310: 12-23.
Impact Factor: 2.668
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Melillo P, Prinster A, Di Iorio V, Olivo G, D'Alterio FM, Cocozza S, Orrico A, Quarantelli M, Testa F, Brunetti A, Simonelli F
* Visual Cortex Activation in Patients With Stargardt Disease (379 views)
Invest Ophth Vis Sci (ISSN: 0146-0404linking, 1552-5783electronic), 2018 Mar 1; 59(3): 1503-1511.
Impact Factor: 3.303
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Monti S, Borrelli P, Tedeschi E, Cocozza S, Palma G
* RESUME: Turning an SWI acquisition into a fast qMRI protocol (510 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2017 Dec 20; 12(12): e0189933-e0189933.
Impact Factor: 2.766
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Longo DL, Aime S
* A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol (621 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 2017 Jul 07; 79(3): 1553-1558.
Impact Factor: 4.082
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Canna A, Prinster A, Monteleone AM, Cantone E, Monteleone P, Volpe U, Maj M, Di Salle F, Esposito F
* Interhemispheric Functional Connectivity in Anorexia and Bulimia Nervosa (360 views)
Eur J Neurosci (ISSN: 0953-816x), 2017 May; 45(9): 1129-1140.
Impact Factor: 2.832
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Segreto S, Fonti R, Ottaviano M, Pellegrino S, Pace L, Damiano V, Palmieri G, Del Vecchio S
* Evaluation of metabolic response with (18)F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors (355 views)
Cancer Imaging (ISSN: 1470-7330, 1470-7330electronic), 2017 Mar 7; 17(1): 10-10.
Impact Factor: 3.016
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Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
* Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging (405 views)
Gastric Cancer (ISSN: 1436-3291, 1436-3291linking), 2016 Dec 19; 20(4): 629-639.
Impact Factor: 5.454
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Lastoria S, Marciello F, Faggiano A, Aloj L, Caraco C, Aurilio M, D'Ambrosio L, Di Gennaro F, Ramundo V, Camera L, De LucaL, Fonti R, Napolitano V, Colao A
* Role of (68)Ga-DOTATATE PET/CT in patients with multiple endocrine neoplasia type 1 (MEN1) (387 views)
Endocrine (ISSN: 1355-008x), 2016 Jun; 52(3): 488-494.
Impact Factor: 3.131
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Tedeschi E, Palma G, Canna A, Cocozza S, Russo C, Borrelli P, Lanzillo R, Angelini V, Postiglione E, Morra VB, Salvatore M, Brunetti A, Quarantelli M
* In vivo dentate nucleus MRI relaxometry correlates with previous administration of Gadolinium-based contrast agents (645 views)
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Impact Factor: 3.967
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Mainenti PP, Pizzuti LM, Segreto S, Comerci M, Fronzo SD, Romano F, Crisci V, Smaldone M, Laccetti E, Storto G, Alfano B, Maurea S, Salvatore M, Pace L
* Diffusion volume (DV) measurement in endometrial and cervical cancer: A new MRI parameter in the evaluation of the tumor grading and the risk classification (1123 views) (PDF 269 views)
Eur J Radiol (ISSN: 0720-048x, 0720-048xlinking), 2016 Jan; 85(1): 113-124.
Impact Factor: 2.462
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Gaia O, Melillo P, Sirio C, D'Alterio FM, Prinster A, Testa F, Brunetti A, Simonelli F, Quarantelli M
* Cerebral Involvement in Stargardt's Disease: A VBM and TBSS Study (648 views)
Invest Ophth Vis Sci (ISSN: 0146-0404, 0146-0404linking, 1552-5783electronic), 2015 Nov; 56(12): 7388-7397.
Impact Factor: 3.427
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Cocozza S, Sacca F, Cervo A, Marsili A, Russo CV, Giorgio SM, De Michele G, Filla A, Brunetti A, Quarantelli M
* Modifications of resting state networks in spinocerebellar ataxia type two (548 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2015 Sep; 30(10): 1382-1390.
Impact Factor: 6.01
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Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Liu S, Ye Y, Comerci M, Alfano B, Salvatore M, Haacke EM, Mancini M
* A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain (880 views) (PDF 301 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Aug 18; 10(8): e0134963-e0134963.
Impact Factor: 3.057
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Cervo A, Cocozza S, Saccà F, Giorgio SM, Morra VB, Tedeschi E, Marsili A, Vacca G, Palma V, Brunetti A, Quarantelli M
* The combined use of conventional MRI and MR spectroscopic imaging increases the diagnostic accuracy in amyotrophic lateral sclerosis (613 views)
Eur J Radiol (ISSN: 0720-048x, 0720-048xlinking), 2015 Jan; 84(1): 151-157.
Impact Factor: 2.593
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Conson M, Cella L, Pacelli R, Comerci M, Liuzzi R, Salvatore M, Quarantelli M
* Automated delineation of brain structures in patients undergoing radiotherapy for primary brain tumors: From atlas to dose-volume histograms (1157 views) (PDF 410 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 0167-8140linking), 2014 Sep; 112(3): 326-331.
Impact Factor: 4.363
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D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S
* A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients (645 views)
Int J Cancer (ISSN: 0020-7136), 2014 Jul 15; 135(2): 379-390.
Impact Factor: 5.085
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Murino L, Granata D, Carfora MF, Selvan SE, Alfano B, Amato U, Larobina M
* Evaluation of supervised methods for the classification of major tissues and subcortical structures in multispectral brain magnetic resonance images (595 views) (PDF 253 views)
Comput Med Imag Grap (ISSN: 0895-6111), 2014 Jul; 38(5): 337-347.
Impact Factor: 1.218
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Iodice D, Di Donato O, Liccardo I, Lamanna L, Segreto S, Salvatore M, Imbriaco M
* Prevalence of extramammary findings on breast MRI: a large retrospective single-centre study (472 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Oct; 118(7): 1109-1118.
Impact Factor: 1.368
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Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (597 views)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
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Comerci M, Elefante A, Strianese D, Senese R, Bonavolonta P, Alfano B, Bonavolonta B, Brunetti A
* Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study (711 views) (PDF 278 views)
Neuroradiol J (ISSN: 1971-4009, 1971-4009print, 1971-4009linking), 2013 Aug; 26(4): 373-379.
Impact Factor: 2.16
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Risitano AM, Imbriaco M, Marando L, Seneca E, Soscia E, Malcovati L, Iori AP, Pane F, Notaro R, Matarazzo M
* From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging (460 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2012 Sep; 158(3): 415-418.
Impact Factor: 4.942
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Vassallo M, Giuseppe M, Quarantelli M, Pastore G, Paladini D
* Choroid plexus carcinoma: Prenatal characterization by 3-dimensional sonography and magnetic resonance imaging perinatal management, and natural history (503 views)
J Ultrasound Med (ISSN: 0278-4297, 1550-9613, 0278-4297linking), 2012 Feb; 31(2): 337-340.
Impact Factor: 1.402
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Bastianello S, Giugni E, Amato MP, Tola MR, Trojano M, Galletti S, Luccichenti G, Quarantelli M, Picconi O, Patti F, COGIMUS
* Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study (435 views) (PDF 249 views)
Bmc Neurol (ISSN: 1471-2377, 1471-2377linking), 2011 Oct 14; 11: 125-125.
Impact Factor: 2.167
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Digilio G, Menchise V, Gianolio E, Catanzaro V, Carrera C, Napolitano R, Fedeli F, Aime S
* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (588 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
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Maruotti GM, Paladini D, Napolitano R, Mazzarelli LL, Russo T, Quarantelli M, D'Armiento MR, Martinelli P
* Prenatal 2D and 3D ultrasound diagnosis of diprosopus: Case report with post-mortem magnetic resonance images (MRI) and review of the literature (702 views)
Prenat Diagn (ISSN: 0197-3851, 0197-3851linking), 2009 Oct; 29(10): 992-994.
Impact Factor: 1.707
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Napolitano R, Maruotti GM, Quarantelli M, Martinelli P, Paladini D
* Prenatal diagnosis of Seckel syndrome on 3-dimensional sonography and magnetic resonance imaging (627 views)
J Ultrasound Med (ISSN: 0278-4297, 1550-9613, 0278-4297linking), 2009 Mar; 28(3): 369-374.
Impact Factor: 1.181
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Digilio G, Catanzaro V, Fedeli F, Gianolio E, Menchise V, Napolitano R, Gringeri C, Aime S
* Targeting exofacial protein thiols with Gd-III complexes. An efficient procedure for MRI cell labelling (423 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2009 Feb 28; (8): 893-895.
Impact Factor: 5.504
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (720 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (815 views) (PDF 283 views)
J Neurol Sci (ISSN: 0022-510x, 0022-510xlinking), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
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De Leva MF, Varrone A, Filla A, Quarantelli M, Bilo L, Piscitelli V, Salvatore E, Ammendola S, Striano S, De Michele G, Bonavita V, Pappata S
* Neuroimaging follow-up in a case of Rasmussen's encephalitis with dyskinesias (568 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2007 Oct 31; 22(14): 2117-2121.
Impact Factor: 3.207
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Imbriaco M, Spinelli L, Cuocolo A, Maurea S, Sica G, Quarantelli M, Pisani A, Liuzzi R, Cianciaruso B, Sabbatini M, Salvatore M
* MRI characterization of myocardial tissue in patients with Fabry's disease (836 views)
Ajr Am J Roentgenol (ISSN: 1546-3141, 0361-803x, 1546-3141electronic), 2007 Mar; 188(3): 850-853.
Impact Factor: 2.47
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Amato U, Larobina M, Antoniadis A, Alfano B
* Segmentation of magnetic resonance brain images through discriminant analysis (787 views) (PDF 274 views)
J Neurosci Methods (ISSN: 0165-0270, 0165-0270linking, 1872-678xelectronic), 2003 Dec 30; 131(1-2): 65-74.
Impact Factor: 1.777
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Quarantelli M, Larobina M, Volpe U, Amati G, Tedeschi E, Ciarmiello A, Brunetti A, Galderisi S, Alfano B
* Stereotaxy-based regional brain volumetry applied to segmented MRI: Validation and results in deficit and nondeficit schizophrenia (676 views) (PDF 248 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 17(1): 373-384.
Impact Factor: 5.624
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Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (861 views) (PDF 628 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1998 Mar; 39(3): 497-499.
Impact Factor: 2.962
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Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (886 views) (PDF 726 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Impact Factor: 3.012
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (386 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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Alfano B, Brunetti A, Ciarmiello A, Salvatore M
Simultaneous display of multiple MR parameters with 'quantitative magnetic color imaging' (643 views) (PDF 663 views)
J Comput Assisted Tomogr (ISSN: 0363-8715), 1992 Jul; 16(4): 634-640.
Impact Factor: 1.263
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64 Records (63 excluding Abstracts).
Total impact factor: 187.015 (184.848 excluding Abstracts).
Total 5 year impact factor: 212.136 (209.506 excluding Abstracts).
Total impact factor: 187.015 (184.848 excluding Abstracts).
Total 5 year impact factor: 212.136 (209.506 excluding Abstracts).
348 views. Last view on Sunday 08 December 2024, 0:57:14
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