Erratum to: The Role of Sleeve Gastrectomy in Reducing Cardiovascular Risk(361 views) Tromba L, Tartaglia F, Carbotta S, Sforza N, Pelle F, Colagiovanni V, Carbotta G, Cavaiola S, Casella G
Obes Surg (ISSN: 0960-8923), 2016 Nov 14; N/D: N/D-N/D.
Surgical Sciences Department, "Sapienza" University of Rome, Rome, Italy., Surgical Sciences Department, "Sapienza" University of Rome, Rome, Italy. francesco.tartaglia@uniroma1.it., Gynecological, Obstetric Sciences Department and Urological Sciences, "Sapienza" University of Rome, Rome, Italy., Department of Experimental Medicine, "Sapienza" University of Rome, Rome, Italy., CNR, IBB, Rome, Italy.,
References: Not available.
Erratum to: The Role of Sleeve Gastrectomy in Reducing Cardiovascular Risk
BACKGROUND:
Obesity is an independent
cardiovascular
risk
factor and a catalyst of other
cardiovascular
risk
factors, such as hypertension, dyslipidemia, type 2 diabetes mellitus (DM2) and metabolic syndrome.
METHODS:
We analyzed
cardiovascular
risk
in obese patients before and after
sleeve
gastrectomy
(SG). To this end, we studied changes in body mass index (BMI), blood chemistry parameters that characterize the
risk
of atherosclerosis and instrumental parameters (objective markers of this
risk
),
namely intima-media thickness (IMT) and flow-mediated dilation (FMD),
the latter reflecting endothelial function. We also considered purely
cardiac parameters-mitral annular plane systolic excursion (MAPSE) and
tricuspid annular plane systolic excursion (TAPSE)-which describe
cardiac
risk
more specifically than the ejection fraction. Alteration of one or more of these parameters determines an increase in
cardiovascular
morbidity and mortality.
RESULTS:
The
results showed that weight loss, in patients undergoing SG, is
accompanied by a reduced BMI and a marked improvement in blood
chemistry, confirming what has already been shown in many other studies,
but the most interesting finding was the effect of SG on the
instrumental markers of atherosclerosis. In particular, carotid IMT was
significantly reduced (p < 0.001) and FMD significantly improved.
MAPSE and TAPSE also improved significantly at both follow-up
assessments (p < 0.001).
CONCLUSIONS:
This
study suggests that SG should be considered from a broader perspective,
i.e. as a weight loss treatment that also improves obesity-related
morbidity and mortality, benefitting both the patient and, in an
economic sense, the society as a whole.
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