Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging (255 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412), 2019 Jul 13; 20(12): 1379-1387.
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Paper type: Journal Article,
Impact factor: 5.26, 5-year impact factor: 3.669
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Keywords: Pet Ct, Epicardial Adipose Tissue, Myocardial Blood Flow, Myocardial Perfusion Reserve,
Affiliations:
*** IBB - CNR ***
Department of Advanced Biomedical Sciences, University Federico II, Via Sergio Pansini 5, Napoli, Italy.
Institute of Biostructure and Bioimaging, National Council of Research, Via Sergio Pansini 5, Napoli, Italy.
Department of Translational Medical Sciences, University Federico II, Via Sergio Pansini 5, Napoli, Italy.
References:
Not available.
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412), 2019 Jul 13; 20(12): 1379-1387.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 5.26, 5-year impact factor: 3.669
Url: Not available.
Keywords: Pet Ct, Epicardial Adipose Tissue, Myocardial Blood Flow, Myocardial Perfusion Reserve,
Affiliations:
*** IBB - CNR ***
Department of Advanced Biomedical Sciences, University Federico II, Via Sergio Pansini 5, Napoli, Italy.
Institute of Biostructure and Bioimaging, National Council of Research, Via Sergio Pansini 5, Napoli, Italy.
Department of Translational Medical Sciences, University Federico II, Via Sergio Pansini 5, Napoli, Italy.
References:
Not available.
Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging
AIMS: We evaluated the relationship between epicardial adipose tissue (EAT) and coronary vascular function assessed by rubidium-82 (82Rb) positron emission tomography/computed tomography (PET/CT) in patients with suspected coronary artery disease (CAD). METHODS AND RESULTS: The study population included 270 patients with suspected CAD and normal myocardial perfusion at stress-rest 82Rb PET/CT. Coronary artery calcium (CAC) score and EAT volume were measured. Absolute myocardial blood flow (MBF) was computed in mL/min/ from the dynamic rest and stress imaging. Myocardial perfusion reserve (MPR) was defined as the ratio of hyperaemic to baseline MBF and it was considered reduced when <2. MPR was normal in 177 (65%) patients and reduced in 93 (35%). Patients with impaired MPR were older (P < 0.001) and had higher CAC score values (P = 0.033), EAT thickness (P = 0.009), and EAT volume (P < 0.001). At univariable logistic regression analysis, age, heart rate reserve (HRR), CAC score, EAT thickness, and EAT volume resulted significant predictors of reduced MPR, but only age (P = 0.002), HRR (P = 0.021), and EAT volume (P = 0.043) were independently associated with reduced MPR, at multivariable analysis. In patients with CAC score 0 (n = 114), a significant relation between EAT volume and MPR (P = 0.014) was observed, while the relationship was not significant (P = 0.21) in patients with CAC score >0 (n = 156). CONCLUSION: In patients with suspected CAD and normal myocardial perfusion, EAT volume predicts hyperaemic MBF and reduced MPR, confirming that visceral pericardium fat may influence coronary vascular function. Thus, EAT evaluation has a potential role in the early identification of coronary vascular dysfunction.
AIMS: We evaluated the relationship between epicardial adipose tissue (EAT) and coronary vascular function assessed by rubidium-82 (82Rb) positron emission tomography/computed tomography (PET/CT) in patients with suspected coronary artery disease (CAD). METHODS AND RESULTS: The study population included 270 patients with suspected CAD and normal myocardial perfusion at stress-rest 82Rb PET/CT. Coronary artery calcium (CAC) score and EAT volume were measured. Absolute myocardial blood flow (MBF) was computed in mL/min/ from the dynamic rest and stress imaging. Myocardial perfusion reserve (MPR) was defined as the ratio of hyperaemic to baseline MBF and it was considered reduced when <2. MPR was normal in 177 (65%) patients and reduced in 93 (35%). Patients with impaired MPR were older (P < 0.001) and had higher CAC score values (P = 0.033), EAT thickness (P = 0.009), and EAT volume (P < 0.001). At univariable logistic regression analysis, age, heart rate reserve (HRR), CAC score, EAT thickness, and EAT volume resulted significant predictors of reduced MPR, but only age (P = 0.002), HRR (P = 0.021), and EAT volume (P = 0.043) were independently associated with reduced MPR, at multivariable analysis. In patients with CAC score 0 (n = 114), a significant relation between EAT volume and MPR (P = 0.014) was observed, while the relationship was not significant (P = 0.21) in patients with CAC score >0 (n = 156). CONCLUSION: In patients with suspected CAD and normal myocardial perfusion, EAT volume predicts hyperaemic MBF and reduced MPR, confirming that visceral pericardium fat may influence coronary vascular function. Thus, EAT evaluation has a potential role in the early identification of coronary vascular dysfunction.
Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging
| ▼ Noninvasive techniques for coronary flow reserve assessment |
Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging
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Zampella E, Assante R, Gaudieri V, Nappi C, Acampa W, Cuocolo A
* Myocardial perfusion reserve by using CZT: It's a long way to the top if you wanna standardize (237 views)
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Mannarino T, Gaudieri V, Acampa W
* Vasodilators and myocardial blood flow by CZT cameras: Make us see further (96 views)
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Zampella E, Acampa W, Assante R, Gaudieri V, Nappi C, Mannarino T, Mainolfi CG, Arumugam P, Petretta M, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in predicting lesion-related outcome (163 views)
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Impact Factor: 5.036
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Acampa W, Assante R, Mannarino T, Zampella E, D'Antonio A, Buongiorno P, Gaudieri V, Nappi C, Giordano A, Mainolfi CG, Petretta M, Cuocolo A
* Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease (171 views)
Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1705-1712.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Gaudieri V, Acampa W, Rozza F, Nappi C, Zampella E, Assante R, Mannarino T, Mainolfi C, Petretta M, Verberne HJ, Arumugam P, Cuocolo A
* Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis (240 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412electronic), 2019 Feb 14; N/D: N/D-N/D.
Impact Factor: 3.669
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Parisi V, Petraglia L, D'Esposito V, Cabaro S, Rengo G, Caruso A, Grimaldi MG, Baldascino F, De Bellis A, Vitale D, Formisano R, Ferro A, Paolillo S, Davin L, Lancellotti P, Formisano P, Perrone Filardi P, Ferrara N, Leosco D
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Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic, 0167-5273linking), 2019 Jan 1; 274: 326-330.
Impact Factor: 3.121
View Export to BibTeX Export to EndNote
Assante R, Zampella E, Arumugam P, Acampa W, Imbriaco M, Tout D, Petretta M, Tonge C, Cuocolo A
* Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease (545 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017; 24(2): 494-501.
Impact Factor: 4.011
View Export to BibTeX Export to EndNote
Parisi V, Rengo G, Perrone-filardi P, Pagano G, Femminella GD, Paolillo S, Petraglia L, Gambino G, Caruso A, Grimaldi MG, Baldascino F, Nolano M, Elia A, Cannavo A, De Bellis A, Coscioni E, Pellegrino T, Cuocolo A, Ferrara N, Leosco D
* Increased Epicardial Adipose Tissue Volume Correlates With Cardiac Sympathetic Denervation in Patients With Heart Failure (293 views)
Circ Res (ISSN: 0009-7330, 1524-4571electronic, 0009-7330linking), 2016 Apr 15; 118(8): 1244-1253.
Impact Factor: 13.965
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Petretta M, Storto G, Pellegrino T, Bonaduce D, Cuocolo A
* Quantitative Assessment of Myocardial Blood Flow with SPECT (568 views)
Prog Cardiovasc Dis (ISSN: 0033-0620), 2015 Jan 3; 57(6): 607-614.
Impact Factor: 4.635
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Cuocolo A, Cittanti C, Acampa W, Larobina M, Petretta M
* Current and Future Status of Blood Flow Tracers (362 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2011; 4(3): 227-236.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Lucignani G, Cuocolo A
Advances in quantitative assessment of myocardial blood flow and coronary reserve (281 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Oct; 36(10): 1687-1692.
Impact Factor: 4.531
View Export to BibTeX Export to EndNote
Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (806 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
View Export to BibTeX Export to EndNote
* Myocardial perfusion reserve by using CZT: It's a long way to the top if you wanna standardize (237 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2021 Jun; 28(3): 885-887.
Impact Factor: 2.811
View Export to BibTeX Export to EndNote
Mannarino T, Gaudieri V, Acampa W
* Vasodilators and myocardial blood flow by CZT cameras: Make us see further (96 views)
J Nucl Cardiol (ISSN: 1071-3581linking, 1532-6551electronic), 2020 Nov 17; N/D: N/D-N/D.
Impact Factor: 3.847
View Export to BibTeX Export to EndNote
Zampella E, Acampa W, Assante R, Gaudieri V, Nappi C, Mannarino T, Mainolfi CG, Arumugam P, Petretta M, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in predicting lesion-related outcome (163 views)
Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1698-1704.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Acampa W, Assante R, Mannarino T, Zampella E, D'Antonio A, Buongiorno P, Gaudieri V, Nappi C, Giordano A, Mainolfi CG, Petretta M, Cuocolo A
* Low-dose dynamic myocardial perfusion imaging by CZT-SPECT in the identification of obstructive coronary artery disease (171 views)
Eur J Nucl Med (ISSN: 1619-7070linking, 1619-7070print, 1619-7089electronic), 2020 Jul; 47(7): 1705-1712.
Impact Factor: 5.036
View Export to BibTeX Export to EndNote
Gaudieri V, Acampa W, Rozza F, Nappi C, Zampella E, Assante R, Mannarino T, Mainolfi C, Petretta M, Verberne HJ, Arumugam P, Cuocolo A
* Coronary vascular function in patients with resistant hypertension and normal myocardial perfusion: a propensity score analysis (240 views)
Eur Heart J-Card Img (ISSN: 2047-2404linking, 2047-2412electronic), 2019 Feb 14; N/D: N/D-N/D.
Impact Factor: 3.669
View Export to BibTeX Export to EndNote
Parisi V, Petraglia L, D'Esposito V, Cabaro S, Rengo G, Caruso A, Grimaldi MG, Baldascino F, De Bellis A, Vitale D, Formisano R, Ferro A, Paolillo S, Davin L, Lancellotti P, Formisano P, Perrone Filardi P, Ferrara N, Leosco D
* Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue (418 views)
Int J Cardiol (ISSN: 0167-5273, 1874-1754electronic, 0167-5273linking), 2019 Jan 1; 274: 326-330.
Impact Factor: 3.121
View Export to BibTeX Export to EndNote
Assante R, Zampella E, Arumugam P, Acampa W, Imbriaco M, Tout D, Petretta M, Tonge C, Cuocolo A
* Quantitative relationship between coronary artery calcium and myocardial blood flow by hybrid rubidium-82 PET/CT imaging in patients with suspected coronary artery disease (545 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017; 24(2): 494-501.
Impact Factor: 4.011
View Export to BibTeX Export to EndNote
Parisi V, Rengo G, Perrone-filardi P, Pagano G, Femminella GD, Paolillo S, Petraglia L, Gambino G, Caruso A, Grimaldi MG, Baldascino F, Nolano M, Elia A, Cannavo A, De Bellis A, Coscioni E, Pellegrino T, Cuocolo A, Ferrara N, Leosco D
* Increased Epicardial Adipose Tissue Volume Correlates With Cardiac Sympathetic Denervation in Patients With Heart Failure (293 views)
Circ Res (ISSN: 0009-7330, 1524-4571electronic, 0009-7330linking), 2016 Apr 15; 118(8): 1244-1253.
Impact Factor: 13.965
View Export to BibTeX Export to EndNote
Petretta M, Storto G, Pellegrino T, Bonaduce D, Cuocolo A
* Quantitative Assessment of Myocardial Blood Flow with SPECT (568 views)
Prog Cardiovasc Dis (ISSN: 0033-0620), 2015 Jan 3; 57(6): 607-614.
Impact Factor: 4.635
View Export to BibTeX Export to EndNote
Cuocolo A, Cittanti C, Acampa W, Larobina M, Petretta M
* Current and Future Status of Blood Flow Tracers (362 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2011; 4(3): 227-236.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Lucignani G, Cuocolo A
Advances in quantitative assessment of myocardial blood flow and coronary reserve (281 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Oct; 36(10): 1687-1692.
Impact Factor: 4.531
View Export to BibTeX Export to EndNote
Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (806 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
View Export to BibTeX Export to EndNote
12 Records (11 excluding Abstracts).
Total impact factor: 53.104 (48.469 excluding Abstracts).
Total 5 year impact factor: 47.383 (43.495 excluding Abstracts).
Total impact factor: 53.104 (48.469 excluding Abstracts).
Total 5 year impact factor: 47.383 (43.495 excluding Abstracts).
255 views. Last view on Monday 30 September 2024, 7:14:52
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