Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type(681 views) Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2008 Aug 15; 14(16): 5209-5219.
Keywords: Aged, Animals, Apoptosis Drug Effects, Blotting, Western, Carcinoma, Non-Small-Cell Lung Drug Therapy Metabolism, Cell Line, Tumor, Female, Humans, Immunoprecipitation, Inositol 1, 5-Trisphosphate Receptors Metabolism, Lung Neoplasms Drug Therapy Metabolism, Membrane Potential, Mitochondrial Drug Effects, Nude, Middle Aged, Mitochondria Drug Effects, Positron-Emission Tomography, Protein Kinase Inhibitors Pharmacology, Proto-Oncogene Proteins C-Bcl-2 Metabolism, Quinazolines Pharmacology, Radiopharmaceuticals Diagnostic Use, Epidermal Growth Factor Drug Effects Metabolism, Signal Transduction Drug Effects Physiology, Technetium Tc 99m Sestamibi Diagnostic Use, Bcl-X Protein Metabolism, Calcium, Epidermal Growth Factor Receptor Kinase Inhibitor, Erlotinib, Gefitinib, Inositol Trisphosphate, Inositol Trisphosphate Receptor Type 3, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Protein Bcl 2, Unclassified Drug, Diagnostic Agent, 5 Trisphosphate Receptor, Quinazoline Derivative, Radiopharmaceutical Agent, Adult, Animal Experiment, Animal Model, Article, Case Report, Controlled Study, Drug Accumulation, Drug Blood Level, Drug Uptake, Human Cell, In Vivo Study, Lung Cancer, Mouse, Nonhuman, Priority Journal, Protein Expression, Protein Interaction, Protein Phosphorylation, Single Photon Emission Computer Tomography, Lung Non Small Cell Cancer, Lung Tumor, Mitochondrial Membrane Potential, Nude Mouse, Positron Emission Tomography, Tumor Cell Line, Western Blotting, Erlotinib Hydrochloride,
Affiliations: *** IBB - CNR ***
Institute of Biostructures and Bioimages, National Research Council.
Department of Experimental Oncology, National Cancer InstituteNaples, Italy
Department of Endocrinology and Molecular and Clinical OncologyNaples, Italy
Biomorphological and Functional Sciences, University of Naples Federico IINaples, Italy
References: Not available.
Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type
Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S * Fusion in Coq(578 views) Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2001; 2178LNCS: 583-596. Impact Factor:0.415 ViewExport to BibTeXExport to EndNote