Paracingulate sulcus morphology in men with early-onset schizophrenia(419 views) Le Provost JB, Bartres-faz D, Paillere-martinot ML, Artiges E, Pappata S, Recasens C, Perez-gomez M, Bernardo M, Baeza I, Bayle F, Martinot JL
Keywords: Adult, Article, Brain, Brain Asymmetry, Clinical Article, Controlled Study, Human, Left Hemisphere, Morphology, Nuclear Magnetic Resonance Imaging, Schizophrenia, Third Trimester Pregnancy, Age Of Onset, Case-Control Studies, Embryonic And Fetal Development, Functional Laterality, Gyrus Cinguli,
Affiliations: *** IBB - CNR ***
INSERM-CEA, Frederic Joliot Hosp. Dept., Orsay, France
Albert Chenevier Hospital, Créteil, France
Dept. of Psychiat. and Psychobiology, University of Barcelona, Barcelona, Spain
Hosp. Clin. i Prov. de Barcelona, Barcelona, Spain
Sainte-Anne Hospital, Paris, France
ERM 0205 Imagerie Cerebrale P., INSERM-CEA, Serv. Hosp. Frederic Joliot, 4 Pl. du Gén. Leclerc, 91401 Orsay Cedex, France
NSERM - CEA, Frederic Joliot Hospital Department, Orsay, France.
References: Not available.
Paracingulate sulcus morphology in men with early-onset schizophrenia
Background: Cingulate dysfunction has been reported in schizophrenia. Although the paracingulate sulcus (PCS) is known to be asymmetric in healthy people, little information is available about its morphology in schizophrenia. Aims: To search for morphological anomalies of the PCS in men with early-onset schizophrenia. Method: The PCS was examined in magnetic resonance images of the brains of men with schizophrenia and 100 healthy men. Results: A significant asymmetry was found in the brains of healthy volunteers, whose sulci were more frequent and more marked in the left hemisphere. In contrast, the sulcus was as frequent in the right as in the left hemisphere in the patient group. Moreover, patients displayed significantly more rightward asymmetry, and overall less-asymmetrical patterns than the comparison group. Conculsions: Since the PCS has developed at 36 weeks of gestation, these findings suggest an impaired maturation of the cingulate region during the third trimester.
Paracingulate sulcus morphology in men with early-onset schizophrenia
No results.
Paracingulate sulcus morphology in men with early-onset schizophrenia
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