Peptides from Royal Jelly: studies on the antimicrobial activity of jelleins, jelleins analogs and synergy with temporins(2144 views) Romanelli A, Moggio L, Montella RC, Campiglia P, Iannaccone M, Capuano F, Pedone C, Capparelli R
Department of Biological Sciences, School of Biotechnological Sciences, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy. alessandra.romanelli@unina.it
Institute of Biostructure and Bioimaging, CNR, Via Mezzocannone 16, 80134 Naples, Italy
Department of Pharmaceutical Science, University of Salerno, 84084 Fisciano, Salerno, Italy
Department of Food Inspection IZS ME, Via Salute 2, 80055 Portici, Italy
References: Not available.
Peptides from Royal Jelly: studies on the antimicrobial activity of jelleins, jelleins analogs and synergy with temporins
Peptides isolated from natural fonts are the object of several studies aimed at finding new molecules possessing antibacterial activity. We focused our studies on peptides originally isolated from the Royal Jelly, the jelleins and on some analogs having a UV reporter at the N- or C-terminus. We found that jelleins are mainly active against gram-positive bacteria; interestingly, they act in synergy with peptides belonging to the family of temporins such as temporin A and temporin B against Staphylococcus aureus A170 and Listeria monocytogenes. Copyright 2011 European Peptide Society and John Wiley & Sons, Ltd.
Peptides from Royal Jelly: studies on the antimicrobial activity of jelleins, jelleins analogs and synergy with temporins
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