Affiliations: Centro per la Medicina Nucleare, Consiglio Nazionale delle Ricerche, Naples, Italy
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Atias, S.W., (1991) Magnetic Resonance Imaging of the Brain and the Spine, , Raven Press, New York
Phelps, M.E., Mazziotta, J.C., Schelbert, H.R., (1985) Positron Emission Tomography and Autoradiography: Principles and Applications for the Brain and the Heart, , Raven Press, New York
Kramer, E.L., Sanger, J.J., (1995) Clinical SPECT Imaging, , Raven Press, New York
Ross, B., Michaelis, T., Clinical applications of magnetic resonance spectroscopy (1994) Magn. Reson. Quart., 10, pp. 191-247
Rosen, B.R., Aronen, H.J., Kwong, K.K., Advances in clinical neuroimaging: Functional MR imaging techniques (1993) Radiographics, 13, pp. 889-896
Belliveau, J.W., Kennedy, D.N., Mckinstry, R.C., Functional mapping of the human visual cortex using magnetic resonance imaging (1991) Science, 254, pp. 716-719
Gordon, R., (1983) Great Medical Disasters, , Hutchinson, London
Abrams, N., Brucker, M.D., (1993) Medical Ethics: A Clinical Textbook End Reference for the Health Care Professions, , MA MIT Press, Cambridge
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Lannotti, F., Fieschi, C., Alfano, B., Simplified, non-invasive PET measurement of blood-brain-barrier permeability (1987) J. Comput. Assist. Tomogr., 11, pp. 390-397
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Lauterbur, P. C., Image formation by induced local interactions: Examples employing nuclear magnetic resonance (1973) Nature, 242, pp. 190-191
Atias, S. W., (1991) Magnetic Resonance Imaging of the Brain and the Spine, , Raven Press, New York
Kelley, R. E., (1994) Functional Neuroimaging, , Futura Publishing Co, Armonk (NY)
Phelps, M. E., Mazziotta, J. C., Schelbert, H. R., (1985) Positron Emission Tomography and Autoradiography: Principles and Applications for the Brain and the Heart, , Raven Press, New York
Kramer, E. L., Sanger, J. J., (1995) Clinical SPECT Imaging, , Raven Press, New York
Rosen, B. R., Aronen, H. J., Kwong, K. K., Advances in clinical neuroimaging: Functional MR imaging techniques (1993) Radiographics, 13, pp. 889-896
Belliveau, J. W., Kennedy, D. N., Mckinstry, R. C., Functional mapping of the human visual cortex using magnetic resonance imaging (1991) Science, 254, pp. 716-719
Kety, S. S., Schmidt, C. F., The nitrous oxide method for the quantitative determination of cerebral blood flow in man: Theory, procedure and normal values (1948) J. Clin. Invest., 27, pp. 476-483
Ingvar, D. H., Lassen, N. A., Regional blood flow of the cerebral cortex determined by krypton-85 (1962) Acta Physiol. Scand., 54, pp. 325-338
Lassen, N. A., Munck, O., The cerebral blood flow in man determined by the use of radioactive krypton (1955) Acta Physiol. Scand., 33, pp. 30-49
Gallen, C. C., Sobel, D. F., Lewin, J. D., Neuromagnetic mapping of brain function (1993) Radiology, 187, pp. 863-868
Shellock, F. G., Kanal, E., (1994) Magnetic Resonance: Bioeffects, Safety and Patient Management, , Raven Press, New York
Beauchamp, T. L., Childless, J. F., (1983) Principles of Biomedical Ethics, , Oxford University Press Inc., New York
Phelps, M. E., Huang, S. C., Hoffman, E. J., Tomographic measurements of local cerebral glucose metabolic rate in humans with (F-18) 2-fluoro-2-deoxygiucose: Validation of a method (1979) Ann. Neurol., 6, pp. 371-388
Jackson, E. F., Narayana, P. A., Falcone, J. C., Reproducibility of nonparametric feature map segmentation for determination of normal human intracranial volumes with MR imaging data (1994) J. Magn. Reson. Imag., 4, pp. 692-700
Advances in brain imaging: A new ethical challenge
Technical advances in the past 25 years permitted substantial advances in the neuroimaging field, expanding the diagnostic and research potentials and significally reducing the use of old invasive imaging techniques for research purposes. The safer procedures now available allow acquisition of reference data, morphological assessment and functional characterisation from healthy volunteers. However, enrollment of volunteers is still a sensitive ethical issue. Ethical problems related to informed consent, for both research and diagnostic procedures, in patients with neuropsychiatric disorders represent an additional crucial issue. Furthermore, with both functional and structural neuroimaging studies, there is a theoretical risk of violation of individual privacy. Research in the neuroimaging field should tend to increase the amount of information obtained through appropriate post-processing procedures, including multimodality image fusion, and to limit stress and discomfort.
Advances in brain imaging: A new ethical challenge
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Advances in brain imaging: A new ethical challenge
Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, Tomaino C, Muraca MG, Leotta A, Lio SG, Pinessi L, Rainero I, Sorbi S, Nee L, Milan G, Pappata S, Postiglione A, Abbamondi N, Forloni G, St George Hyslop P, Rogaeva E, Bugiani O, Giaccone G, Foncin JF, Spillantini MG, Puccio G * Worldwide distribution of PSEN1 Met146Leu mutation: A large variability for a founder mutation(761 views) Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2010 Mar 9; 74(10): 798-806. Impact Factor:8.017 ViewExport to BibTeXExport to EndNote