Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status (356 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 5.799, 5-year impact factor: 1.273
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33646406297&partnerID=40&md5=e9c726c99f1a5a25d24475f11c00d46d
Keywords: Corticotropin, Hydrocortisone, Adrenal Cortex Adenoma, Adrenal Cortex Carcinoma, Adult, Article, Bone Demineralization, Bone Density, Bone Turnover, Controlled Study, Cushing Disease, Dual Energy X Ray Absorptiometry, Female, Gonad, Human, Hypophysis Adenoma, Major Clinical Study, Osteolysis, Pathophysiology, Priority Journal, Vertebra Fracture, Adolescent, Adrenal Gland Neoplasms, Adrenocorticotropic Hormone, Aged, Biological Markers, Body Mass Index, Pathologic, Case-Control Studies, Cross-Sectional Studies, Middle Aged, Ovary, Prospective Studies, Risk Factors, Spinal Fractures, Testis,
Affiliations:
*** IBB - CNR ***
Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, 80131 Naples, Italy
Department of Biomorphological and Functional Sciences, Federico II University of Naples, 80131 Naples, Italy
References:
Cushing, H., The basophil adenomas of the pituitary body and their clinical manifestation (pituitary basophilism) (1932) Bull Johns Hopkins Hosp, 50, pp. 137-19
Canalis, E., Mechanisms of glucocorticoid action in bone: Implications for glucocorticoid-induced osteoporosis (1996) J Clin Endocrinol Metab, 81, pp. 3441-3447
Borelli, A., Leite, M.O., Correa, P.H., Jorgetti, V., Marcondes, J.A., Batalha, J.R., Cintra, A.B., Wajchenberg, B.L., Bone histomorphometry in Cushing's syndrome (1992) J Endocrinol Invest, 15, pp. 783-787
Reid, I.R., Glucocorticoid effects on bone (1998) J Clin Endocrinol Metab, 83, pp. 1860-1861. , Editorial
Lukert, B.P., Raisz, L.G., Glucocorticoid-induced osteoporosis: Pathogenesis and management (1990) Ann Int Med, 112, pp. 352-364
Pereira, R.M., Delany, A.M., Canalis, E., Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture (2001) Bone, 28, pp. 484-490
Rubin, M.R., Bilezikian, J.P., The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: A reexamination of the evidence (2002) J Clin Endocrinol Metab, 87, pp. 4033-4041
Khanine, V., Fournier, J.J., Requeda, E., Luton, J.P., Simon, F., Crouzet, Osteoporotic fractures at presentation of Cushing's disease: Two case reports and literature review (2000) Joint Bone Spine, 67, pp. 341-345
Freehill, A.K., Lenke, L.G., Severe kyphosis secondary to glucocorticoid-induced osteoporosis in a young adult with Cushing's disease. A case report and literature review (1999) Spine, 24, pp. 189-193
Vestergaard, P., Lindholm, J., Jorgensen, J.O., Hagen, C., Hoeck, H.C., Laurberg, P., Rejnmark, L., Mosekilde, L., Increased risk of osteoporotic fractures in patients with Cushing's syndrome (2002) Eur J Endocrinol, 146, pp. 51-56
Lado-Abeal, J., Rodriguez-Arnao, J., Newell-Price, J.D.C., Perry, L.A., Grossman, A.B., Besser, G.M., Trainer, P.J., Menstrual abnormalities in women with Cushing's disease are correlated with hypercortisolemia rather than raised circulating androgen levels (1998) J Clin Endocrinol Metab, 83, pp. 3083-3088
Barbetta, L., Dall'Asta, C., Re, T., Colombo, P., Travaglini, P., Ambrosi, B., Androgen secretion in ectopic ACTH syndrome and in Cushing's disease: Modifications before and after surgery (2001) Horm Metab Res, 33, pp. 596-601
Kaltsas, G.A., Korbonits, M., Isidori, A.M., Webb, J.A.W., Trainer, P.J., Monson, J.P., Besser, G.M., Grossman, A.B., How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome? (2000) Clin Endocrinol, 53, pp. 493-500. , Oxf
Fitzpatric, L.A., Glucocorticoid-induced osteoporosis (1994) Osteoporosis, pp. 202-226. , Marcus R, ed. Boston: Blackwell Scientific
Castelo-Branco, C., Gomez, O., Pons, F., Martinez De Osaba, M.J., Balasch, J., Antoni Vanrell, J., Secreting ovarian tumors may protect women from osteoporosis (2003) Gynecol Oncol, 88, pp. 149-152
Adami, S., Zamberlan, N., Castello, R., Tosi, F., Gatti, D., Moghetti, P., Effect of hyperandrogenism and menstrual cycle abnormalities on bone mass and bone turnover in young women (1998) Clin Endocrinol, 48, pp. 169-173. , Oxf
Sipahi, S., Tuzun, S., Ozaras, R., Calis, H.T., Tuzun, F., Karayel, T., Bone mineral density in women with sarcoidosis (2004) J Bone Miner Metab, 22, pp. 48-52
Karavitaki, N., Ioannidis, G., Giannakopoulos, F., Mavrokefalos, P., Thalassinos, N., Evaluation of bone mineral density of the peripheral skeleton in preand postmenopausal women with newly diagnosed endogenous Cushing's syndrome (2004) Clin Endocrinol, 60, pp. 264-270. , Oxf
Del Puente, A., Heyse, S.P., Mandes, M.G., Mantova, D., Carpinelli, A., Nutile, G., Oriente, P., Epidemiology of osteoporosis in women in southern Italy (1998) Aging Clin Exp Res, 10, pp. 53-58
Minne, H.W., Leidig, G., Wüster, C., Siromachhkostov, L., Baldauf, G., Bickel, R., Sauer, P., Ziegler, R., A newly defined spine deformity index (SDI) to quantitative vertebral crush fractures in patients with osteoporosis (1988) Bone Miner J, 3, pp. 335-349
Melton, L.J., Kan, S.H., Frye, K.M., Wahner, H.W., O'Fallon, W.M., Riggs, B., Epidemiology of vertebral fractures in women (1989) Am J Epidemiol, 124, pp. 1000-1011
Critchlow, D.E., Fligner, M.A., On distribution-free multiple comparisons in the one-way analysis of variance (1991) Commun Stat Theor Methods, 20, pp. 127-139
Minetto, M., Reimondo, G., Osella, G., Ventura, M., Angeli, A., Terzolo, M., Bone loss is more severe in primary adrenal than in pituitary-dependent Cushing's syndrome (2004) Osteoporos Int, 11, pp. 855-861
Ohmori, N., Nomura, K., Ohmori, K., Kato, Y., Itoh, T., Takano, K., Osteoporosis is more prevalent in adrenal than in pituitary Cushing's syndrome (2003) Endocr J, 50, pp. 1-7
Chiodini, I., Guglielmi, G., Battista, C., Carnevale, V., Torlontano, M., Cammista, M., Trischitta, V., Scillitani, A., Spinal volumetric bone mineral density and vertebral fractures in female patients with adrenal incidentalomas: The effects of subclinical hypercortisolism and gonadal status (2004) J Clin Endocrinol Metab, 89, pp. 2237-2241
Van Staa, T.P., Leufkens, H.G.M., Abenhaim, L., Zhang, B., Cooper, C., Use of corticosteroids and risk of fractures (2000) J Bone Miner Res, 15, pp. 993-1000
Steinbuch, M., Youket, T.E., Cohen, S., Oral glucocorticoid use is associated with an increased risk of fracture (2004) Osteoporos Int, 15, pp. 323-328
Di Somma, C., Pivonello, R., Loche, S., Faggiano, A., Klain, M., Salvatore, M., Lombardi, G., Colao, A., Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (2003) Clin Endocrinol, 58, pp. 302-308. , Oxf
Catargi, B., Tabarin, A., Basse-Cathalinant, B., Ducassou, D., Roger, P., Development of bone mineral density after cure of Cushing's syndrome (1996) Ann Endocrinol, 57, pp. 203-208. , Paris
Hermus, A.R., Smals, A., Swinkels, L.M., Huysmans, D.A., Pieters, G.F., Sweep, C.F., Corstens, F.H., Kloppenborg, P.W., Bone mineral density and bone turnover before and after cure of Cushing's syndrome (1995) J Clin Endocrinol Metab, 80, pp. 2859-2865
Canalis, E., Bilezikian, J.P., Angeli, A., Giustina, A., Perspectives on glucocorticoid-induced osteoporosis (2004) Bone, 34, pp. 593-598
Compston, J., Glucocorticoid-induced osteoporosis (2003) Horm Res, 60 (3 SUPPL.), pp. 77-79
Di Somma, C., Colao, A., Pivonello, R., Klain, M., Faggiano, A., Tripodi, F.S., Merola, B., Lombardi, G., Effectiveness of chronic treatment with alendronate in the osteoporosis of Cushing's disease (1998) Clin Endocrinol, 48, pp. 655-662. , Oxf
Chiodini, I., Carnevale, V., Tortolano, M., Fusilli, S., Guglielmi, G., Pileri, M., Modoni, S., Scillitani, A., Alteration of bone turnover and bone mass at different skeletal sites due to pure glucocorticoid excess: Study in eumenorrheic patients with Cushing's syndrome (1998) J Clin Endocrinol Metab, 83, pp. 1863-1867
Tauchmanovà, L., Rossi, R., Nuzzo, V., Del Puente, A., Esposito, A., Pizzi, C., Fonderico, F., Lombardi, G., Bone loss determined by quantitative ultrasonometry correlates with the disease activity in patients with different degree of endogenous glucocorticoid excess due to adrenal mass (2001) Eur J Endocrinol, 145, pp. 241-247
Sartorio, A., Conti, A., Ferrero, S., Giambona, S., Re, T., Passini, E., Ambrosi, B., Evaluation of markers of bone and collagen turnover in patients with active and preclinical Cushing's syndrome and in patients with adrenal incidentaloma (1998) Eur J Endocrinol, 138, pp. 146-152
Reid, I. R., Glucocorticoid effects on bone (1998) J Clin Endocrinol Metab, 83, pp. 1860-1861. , Editorial
Lukert, B. P., Raisz, L. G., Glucocorticoid-induced osteoporosis: Pathogenesis and management (1990) Ann Int Med, 112, pp. 352-364
Pereira, R. M., Delany, A. M., Canalis, E., Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture (2001) Bone, 28, pp. 484-490
Rubin, M. R., Bilezikian, J. P., The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: A reexamination of the evidence (2002) J Clin Endocrinol Metab, 87, pp. 4033-4041
Freehill, A. K., Lenke, L. G., Severe kyphosis secondary to glucocorticoid-induced osteoporosis in a young adult with Cushing's disease. A case report and literature review (1999) Spine, 24, pp. 189-193
Kaltsas, G. A., Korbonits, M., Isidori, A. M., Webb, J. A. W., Trainer, P. J., Monson, J. P., Besser, G. M., Grossman, A. B., How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome? (2000) Clin Endocrinol, 53, pp. 493-500. , Oxf
Fitzpatric, L. A., Glucocorticoid-induced osteoporosis (1994) Osteoporosis, pp. 202-226. , Marcus R, ed. Boston: Blackwell Scientific
Minne, H. W., Leidig, G., W ster, C., Siromachhkostov, L., Baldauf, G., Bickel, R., Sauer, P., Ziegler, R., A newly defined spine deformity index (SDI) to quantitative vertebral crush fractures in patients with osteoporosis (1988) Bone Miner J, 3, pp. 335-349
Melton, L. J., Kan, S. H., Frye, K. M., Wahner, H. W., O'Fallon, W. M., Riggs, B., Epidemiology of vertebral fractures in women (1989) Am J Epidemiol, 124, pp. 1000-1011
Critchlow, D. E., Fligner, M. A., On distribution-free multiple comparisons in the one-way analysis of variance (1991) Commun Stat Theor Methods, 20, pp. 127-139
Van Staa, T. P., Leufkens, H. G. M., Abenhaim, L., Zhang, B., Cooper, C., Use of corticosteroids and risk of fractures (2000) J Bone Miner Res, 15, pp. 993-1000
Hermus, A. R., Smals, A., Swinkels, L. M., Huysmans, D. A., Pieters, G. F., Sweep, C. F., Corstens, F. H., Kloppenborg, P. W., Bone mineral density and bone turnover before and after cure of Cushing's syndrome (1995) J Clin Endocrinol Metab, 80, pp. 2859-2865
Tauchmanov, L., Rossi, R., Nuzzo, V., Del Puente, A., Esposito, A., Pizzi, C., Fonderico, F., Lombardi, G., Bone loss determined by quantitative ultrasonometry correlates with the disease activity in patients with different degree of endogenous glucocorticoid excess due to adrenal mass (2001) Eur J Endocrinol, 145, pp. 241-247
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 5.799, 5-year impact factor: 1.273
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33646406297&partnerID=40&md5=e9c726c99f1a5a25d24475f11c00d46d
Keywords: Corticotropin, Hydrocortisone, Adrenal Cortex Adenoma, Adrenal Cortex Carcinoma, Adult, Article, Bone Demineralization, Bone Density, Bone Turnover, Controlled Study, Cushing Disease, Dual Energy X Ray Absorptiometry, Female, Gonad, Human, Hypophysis Adenoma, Major Clinical Study, Osteolysis, Pathophysiology, Priority Journal, Vertebra Fracture, Adolescent, Adrenal Gland Neoplasms, Adrenocorticotropic Hormone, Aged, Biological Markers, Body Mass Index, Pathologic, Case-Control Studies, Cross-Sectional Studies, Middle Aged, Ovary, Prospective Studies, Risk Factors, Spinal Fractures, Testis,
Affiliations:
*** IBB - CNR ***
Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, 80131 Naples, Italy
Department of Biomorphological and Functional Sciences, Federico II University of Naples, 80131 Naples, Italy
References:
Cushing, H., The basophil adenomas of the pituitary body and their clinical manifestation (pituitary basophilism) (1932) Bull Johns Hopkins Hosp, 50, pp. 137-19
Canalis, E., Mechanisms of glucocorticoid action in bone: Implications for glucocorticoid-induced osteoporosis (1996) J Clin Endocrinol Metab, 81, pp. 3441-3447
Borelli, A., Leite, M.O., Correa, P.H., Jorgetti, V., Marcondes, J.A., Batalha, J.R., Cintra, A.B., Wajchenberg, B.L., Bone histomorphometry in Cushing's syndrome (1992) J Endocrinol Invest, 15, pp. 783-787
Reid, I.R., Glucocorticoid effects on bone (1998) J Clin Endocrinol Metab, 83, pp. 1860-1861. , Editorial
Lukert, B.P., Raisz, L.G., Glucocorticoid-induced osteoporosis: Pathogenesis and management (1990) Ann Int Med, 112, pp. 352-364
Pereira, R.M., Delany, A.M., Canalis, E., Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture (2001) Bone, 28, pp. 484-490
Rubin, M.R., Bilezikian, J.P., The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: A reexamination of the evidence (2002) J Clin Endocrinol Metab, 87, pp. 4033-4041
Khanine, V., Fournier, J.J., Requeda, E., Luton, J.P., Simon, F., Crouzet, Osteoporotic fractures at presentation of Cushing's disease: Two case reports and literature review (2000) Joint Bone Spine, 67, pp. 341-345
Freehill, A.K., Lenke, L.G., Severe kyphosis secondary to glucocorticoid-induced osteoporosis in a young adult with Cushing's disease. A case report and literature review (1999) Spine, 24, pp. 189-193
Vestergaard, P., Lindholm, J., Jorgensen, J.O., Hagen, C., Hoeck, H.C., Laurberg, P., Rejnmark, L., Mosekilde, L., Increased risk of osteoporotic fractures in patients with Cushing's syndrome (2002) Eur J Endocrinol, 146, pp. 51-56
Lado-Abeal, J., Rodriguez-Arnao, J., Newell-Price, J.D.C., Perry, L.A., Grossman, A.B., Besser, G.M., Trainer, P.J., Menstrual abnormalities in women with Cushing's disease are correlated with hypercortisolemia rather than raised circulating androgen levels (1998) J Clin Endocrinol Metab, 83, pp. 3083-3088
Barbetta, L., Dall'Asta, C., Re, T., Colombo, P., Travaglini, P., Ambrosi, B., Androgen secretion in ectopic ACTH syndrome and in Cushing's disease: Modifications before and after surgery (2001) Horm Metab Res, 33, pp. 596-601
Kaltsas, G.A., Korbonits, M., Isidori, A.M., Webb, J.A.W., Trainer, P.J., Monson, J.P., Besser, G.M., Grossman, A.B., How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome? (2000) Clin Endocrinol, 53, pp. 493-500. , Oxf
Fitzpatric, L.A., Glucocorticoid-induced osteoporosis (1994) Osteoporosis, pp. 202-226. , Marcus R, ed. Boston: Blackwell Scientific
Castelo-Branco, C., Gomez, O., Pons, F., Martinez De Osaba, M.J., Balasch, J., Antoni Vanrell, J., Secreting ovarian tumors may protect women from osteoporosis (2003) Gynecol Oncol, 88, pp. 149-152
Adami, S., Zamberlan, N., Castello, R., Tosi, F., Gatti, D., Moghetti, P., Effect of hyperandrogenism and menstrual cycle abnormalities on bone mass and bone turnover in young women (1998) Clin Endocrinol, 48, pp. 169-173. , Oxf
Sipahi, S., Tuzun, S., Ozaras, R., Calis, H.T., Tuzun, F., Karayel, T., Bone mineral density in women with sarcoidosis (2004) J Bone Miner Metab, 22, pp. 48-52
Karavitaki, N., Ioannidis, G., Giannakopoulos, F., Mavrokefalos, P., Thalassinos, N., Evaluation of bone mineral density of the peripheral skeleton in preand postmenopausal women with newly diagnosed endogenous Cushing's syndrome (2004) Clin Endocrinol, 60, pp. 264-270. , Oxf
Del Puente, A., Heyse, S.P., Mandes, M.G., Mantova, D., Carpinelli, A., Nutile, G., Oriente, P., Epidemiology of osteoporosis in women in southern Italy (1998) Aging Clin Exp Res, 10, pp. 53-58
Minne, H.W., Leidig, G., Wüster, C., Siromachhkostov, L., Baldauf, G., Bickel, R., Sauer, P., Ziegler, R., A newly defined spine deformity index (SDI) to quantitative vertebral crush fractures in patients with osteoporosis (1988) Bone Miner J, 3, pp. 335-349
Melton, L.J., Kan, S.H., Frye, K.M., Wahner, H.W., O'Fallon, W.M., Riggs, B., Epidemiology of vertebral fractures in women (1989) Am J Epidemiol, 124, pp. 1000-1011
Critchlow, D.E., Fligner, M.A., On distribution-free multiple comparisons in the one-way analysis of variance (1991) Commun Stat Theor Methods, 20, pp. 127-139
Minetto, M., Reimondo, G., Osella, G., Ventura, M., Angeli, A., Terzolo, M., Bone loss is more severe in primary adrenal than in pituitary-dependent Cushing's syndrome (2004) Osteoporos Int, 11, pp. 855-861
Ohmori, N., Nomura, K., Ohmori, K., Kato, Y., Itoh, T., Takano, K., Osteoporosis is more prevalent in adrenal than in pituitary Cushing's syndrome (2003) Endocr J, 50, pp. 1-7
Chiodini, I., Guglielmi, G., Battista, C., Carnevale, V., Torlontano, M., Cammista, M., Trischitta, V., Scillitani, A., Spinal volumetric bone mineral density and vertebral fractures in female patients with adrenal incidentalomas: The effects of subclinical hypercortisolism and gonadal status (2004) J Clin Endocrinol Metab, 89, pp. 2237-2241
Van Staa, T.P., Leufkens, H.G.M., Abenhaim, L., Zhang, B., Cooper, C., Use of corticosteroids and risk of fractures (2000) J Bone Miner Res, 15, pp. 993-1000
Steinbuch, M., Youket, T.E., Cohen, S., Oral glucocorticoid use is associated with an increased risk of fracture (2004) Osteoporos Int, 15, pp. 323-328
Di Somma, C., Pivonello, R., Loche, S., Faggiano, A., Klain, M., Salvatore, M., Lombardi, G., Colao, A., Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (2003) Clin Endocrinol, 58, pp. 302-308. , Oxf
Catargi, B., Tabarin, A., Basse-Cathalinant, B., Ducassou, D., Roger, P., Development of bone mineral density after cure of Cushing's syndrome (1996) Ann Endocrinol, 57, pp. 203-208. , Paris
Hermus, A.R., Smals, A., Swinkels, L.M., Huysmans, D.A., Pieters, G.F., Sweep, C.F., Corstens, F.H., Kloppenborg, P.W., Bone mineral density and bone turnover before and after cure of Cushing's syndrome (1995) J Clin Endocrinol Metab, 80, pp. 2859-2865
Canalis, E., Bilezikian, J.P., Angeli, A., Giustina, A., Perspectives on glucocorticoid-induced osteoporosis (2004) Bone, 34, pp. 593-598
Compston, J., Glucocorticoid-induced osteoporosis (2003) Horm Res, 60 (3 SUPPL.), pp. 77-79
Di Somma, C., Colao, A., Pivonello, R., Klain, M., Faggiano, A., Tripodi, F.S., Merola, B., Lombardi, G., Effectiveness of chronic treatment with alendronate in the osteoporosis of Cushing's disease (1998) Clin Endocrinol, 48, pp. 655-662. , Oxf
Chiodini, I., Carnevale, V., Tortolano, M., Fusilli, S., Guglielmi, G., Pileri, M., Modoni, S., Scillitani, A., Alteration of bone turnover and bone mass at different skeletal sites due to pure glucocorticoid excess: Study in eumenorrheic patients with Cushing's syndrome (1998) J Clin Endocrinol Metab, 83, pp. 1863-1867
Tauchmanovà, L., Rossi, R., Nuzzo, V., Del Puente, A., Esposito, A., Pizzi, C., Fonderico, F., Lombardi, G., Bone loss determined by quantitative ultrasonometry correlates with the disease activity in patients with different degree of endogenous glucocorticoid excess due to adrenal mass (2001) Eur J Endocrinol, 145, pp. 241-247
Sartorio, A., Conti, A., Ferrero, S., Giambona, S., Re, T., Passini, E., Ambrosi, B., Evaluation of markers of bone and collagen turnover in patients with active and preclinical Cushing's syndrome and in patients with adrenal incidentaloma (1998) Eur J Endocrinol, 138, pp. 146-152
Reid, I. R., Glucocorticoid effects on bone (1998) J Clin Endocrinol Metab, 83, pp. 1860-1861. , Editorial
Lukert, B. P., Raisz, L. G., Glucocorticoid-induced osteoporosis: Pathogenesis and management (1990) Ann Int Med, 112, pp. 352-364
Pereira, R. M., Delany, A. M., Canalis, E., Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture (2001) Bone, 28, pp. 484-490
Rubin, M. R., Bilezikian, J. P., The role of parathyroid hormone in the pathogenesis of glucocorticoid-induced osteoporosis: A reexamination of the evidence (2002) J Clin Endocrinol Metab, 87, pp. 4033-4041
Freehill, A. K., Lenke, L. G., Severe kyphosis secondary to glucocorticoid-induced osteoporosis in a young adult with Cushing's disease. A case report and literature review (1999) Spine, 24, pp. 189-193
Kaltsas, G. A., Korbonits, M., Isidori, A. M., Webb, J. A. W., Trainer, P. J., Monson, J. P., Besser, G. M., Grossman, A. B., How common are polycystic ovaries and the polycystic ovarian syndrome in women with Cushing's syndrome? (2000) Clin Endocrinol, 53, pp. 493-500. , Oxf
Fitzpatric, L. A., Glucocorticoid-induced osteoporosis (1994) Osteoporosis, pp. 202-226. , Marcus R, ed. Boston: Blackwell Scientific
Minne, H. W., Leidig, G., W ster, C., Siromachhkostov, L., Baldauf, G., Bickel, R., Sauer, P., Ziegler, R., A newly defined spine deformity index (SDI) to quantitative vertebral crush fractures in patients with osteoporosis (1988) Bone Miner J, 3, pp. 335-349
Melton, L. J., Kan, S. H., Frye, K. M., Wahner, H. W., O'Fallon, W. M., Riggs, B., Epidemiology of vertebral fractures in women (1989) Am J Epidemiol, 124, pp. 1000-1011
Critchlow, D. E., Fligner, M. A., On distribution-free multiple comparisons in the one-way analysis of variance (1991) Commun Stat Theor Methods, 20, pp. 127-139
Van Staa, T. P., Leufkens, H. G. M., Abenhaim, L., Zhang, B., Cooper, C., Use of corticosteroids and risk of fractures (2000) J Bone Miner Res, 15, pp. 993-1000
Hermus, A. R., Smals, A., Swinkels, L. M., Huysmans, D. A., Pieters, G. F., Sweep, C. F., Corstens, F. H., Kloppenborg, P. W., Bone mineral density and bone turnover before and after cure of Cushing's syndrome (1995) J Clin Endocrinol Metab, 80, pp. 2859-2865
Tauchmanov, L., Rossi, R., Nuzzo, V., Del Puente, A., Esposito, A., Pizzi, C., Fonderico, F., Lombardi, G., Bone loss determined by quantitative ultrasonometry correlates with the disease activity in patients with different degree of endogenous glucocorticoid excess due to adrenal mass (2001) Eur J Endocrinol, 145, pp. 241-247
Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status
Introduction: The effects of endogenous cortisol (F) excess on bone mass and vertebral fractures have still not been thoroughly investigated. The aim of this cross-sectional case-control study was to investigate factors influencing bone demineralization and vertebral fractures in different conditions of F excess, i.e. Cushing's disease and adrenal and ectopic Cushing's syndrome. Materials and Methods: Eighty consecutive patients and 80 controls were prospectively enrolled: 37 patients (21 females) with pituitary ACTH-secreting adenoma, 18 (14 females) with adrenocortical adenoma, 15 (11 females) with adrenal carcinoma of mixed secretion, and 10 (three females) with ectopic ACTH secretion. The groups had similar age. At diagnosis, bone mineral density (BMD) was determined by the dual-energy x-ray absorptiometry technique at the lumbar spine (L1-L4) and femoral neck; vertebral fractures were investigated by standard spinal radiographs. Results: When comparing the groups with different etiology of F excess, the patients with ectopic ACTH secretion had higher F and lower BMD values than the other subgroups. Morning F (P = 0.03) and testosterone levels (P = 0.04) correlated with lumbar BMD. Vertebral fractures were found in 61 (76%) of the patients, were multiple in 52 (85%) of the cases, and clinically evident in 32 (52%). Only multiple fractures were more frequent in patients with ectopic ACTH hypersecretion (P < 0.05). Lumbar spine BMD was the best predictor of vertebral fractures (P < 0.01). Surprisingly, amenorrheic and eumenorrheic women had similar BMD values and fracture prevalence. Conclusion: A high prevalence (76%) of vertebral fracture was revealed, regardless of the etiology of the patients' hypercortisolism. The harmful effects of F excess at the spine were partly counterbalanced by the increased androgen production but were not affected by gonadal status in women. Copyright © 2006 by The Endocrine Society.
Introduction: The effects of endogenous cortisol (F) excess on bone mass and vertebral fractures have still not been thoroughly investigated. The aim of this cross-sectional case-control study was to investigate factors influencing bone demineralization and vertebral fractures in different conditions of F excess, i.e. Cushing's disease and adrenal and ectopic Cushing's syndrome. Materials and Methods: Eighty consecutive patients and 80 controls were prospectively enrolled: 37 patients (21 females) with pituitary ACTH-secreting adenoma, 18 (14 females) with adrenocortical adenoma, 15 (11 females) with adrenal carcinoma of mixed secretion, and 10 (three females) with ectopic ACTH secretion. The groups had similar age. At diagnosis, bone mineral density (BMD) was determined by the dual-energy x-ray absorptiometry technique at the lumbar spine (L1-L4) and femoral neck; vertebral fractures were investigated by standard spinal radiographs. Results: When comparing the groups with different etiology of F excess, the patients with ectopic ACTH secretion had higher F and lower BMD values than the other subgroups. Morning F (P = 0.03) and testosterone levels (P = 0.04) correlated with lumbar BMD. Vertebral fractures were found in 61 (76%) of the patients, were multiple in 52 (85%) of the cases, and clinically evident in 32 (52%). Only multiple fractures were more frequent in patients with ectopic ACTH hypersecretion (P < 0.05). Lumbar spine BMD was the best predictor of vertebral fractures (P < 0.01). Surprisingly, amenorrheic and eumenorrheic women had similar BMD values and fracture prevalence. Conclusion: A high prevalence (76%) of vertebral fracture was revealed, regardless of the etiology of the patients' hypercortisolism. The harmful effects of F excess at the spine were partly counterbalanced by the increased androgen production but were not affected by gonadal status in women. Copyright © 2006 by The Endocrine Society.
Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status
No results. |
Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status
Other filter: ([btitle,keywords] "Corticotropin" OR [b ...
Tabbì G, Magrì A, Giuffrida A, Lanza V, Pappalardo G, Naletova I, Nicoletti VG, Attanasio F, Rizzarelli E
* Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity (462 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015 Jan; 142: 39-46.
Impact Factor: 3.205
View Export to BibTeX Export to EndNote
Dynkevich Y, Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J
* Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive (1669 views)
Endocrine Reviews (ISSN: 0163-769x), 2013 Dec; 34(6): 798-826.
Impact Factor: 19.358
View Export to BibTeX Export to EndNote
De Rosa A, Rinaldi C, Tucci T, Pappata S, Rossi F, Morra VB, Faggiano A, Colao A, De Michele G
* Co-existence of primary hyperparathyroidism and Parkinson's disease in three patients: An incidental finding? (379 views)
Parkinsonism Relat D (ISSN: 1353-8020, 1873-5126, 1873-5126electronic), 2011 Dec; 17(10): 771-773.
Impact Factor: 3.795
View Export to BibTeX Export to EndNote
Maurea S, Imbriaco M, Mollica C, Pace L, Salvatore M
* Quantitative Imaging Characterization Of Hypersecreting Or Non-Hypersecreting Adrenal Adenomas: Comparison Between Iodine-131 Nor-Cholesterol Uptake And Magnetic Resonance Signal Intensity Ratios (284 views)
Nuclear Medicine Communications (ISSN: 1473-5628, 0143-3636), 2011 Jun; 32(6): 535-541.
Impact Factor: 1.404
View Export to BibTeX Export to EndNote
Maurea S, Soricelli A, Salvatore M
* Characterization of hypersecreting or non-hypersecreting adrenal adenomas: Comparison between iodine-131 nor-cholesterol scintigraphy and magnetic resonance imaging (315 views) (PDF 247 views)
Curr Radiopharm (ISSN: 1874-4710, 1874-4729), 2009; 2(1): 56-62.
Impact Factor: 0.643
View Export to BibTeX Export to EndNote
De Leva MF, Varrone A, Filla A, Quarantelli M, Bilo L, Piscitelli V, Salvatore E, Ammendola S, Striano S, De Michele G, Bonavita V, Pappata S
* Neuroimaging follow-up in a case of Rasmussen's encephalitis with dyskinesias (322 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2007 Oct 31; 22(14): 2117-2121.
Impact Factor: 3.207
View Export to BibTeX Export to EndNote
Tauchmanova L, Pivonello R, De Martino MC, Rusciano A, De Leo M, Ruosi C, Mainolfi C, Lombardi G, Salvatore M, Colao A
* Effects of sex steroids on bone in women with subclinical or overt endogenous hypercortisolism (368 views)
Eur J Endocrinol (ISSN: 0804-4643), 2007 Sep; 157(3): 359-366.
Impact Factor: 3.239
View Export to BibTeX Export to EndNote
Maurea S, Imbriaco M, D'Angelillo M, Mollica C, Camera L, Salvatore M
* Diagnostic accuracy of chemical-shift MR imaging to differentiate between adrenal adenomas and non adenoma adrenal lesions (327 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Sep; 111(5): 674-686.
Impact Factor: 1.368
View Export to BibTeX Export to EndNote
Tauchmanovà L, Colao A, Marzano LA, Sparano L, Camera L, Rossi A, Palmieri G, Marzano E, Salvatore M, Pettinato G, Lombardi G, Rossi R
* Andrenocortical carcinomas: Twelve-year prospective experience (294 views)
World J Surg (ISSN: 0364-2313), 2004 Sep; 28(9): 896-903.
Impact Factor: 1.952
View Export to BibTeX Export to EndNote
Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (349 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (459 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
Impact Factor: 2.767
View Export to BibTeX Export to EndNote
Maurea S, Klain M, Mainolfi C, Ziviello M, Salvatore M
* The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses (269 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2001 Jun; 42(6): 884-892.
Impact Factor: 4.51
View Export to BibTeX Export to EndNote
Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (344 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
View Export to BibTeX Export to EndNote
Maurea S, Mainolfi C, Bazzicalupo L, Panico MR, Imparato C, Alfano B, Ziviello M, Salvatore M
Imaging of adrenal tumors using FDG PET: comparison of benign and malignant lesions (355 views) (PDF 247 views)
Ajr Am J Roentgenol (ISSN: 0361-803x, 0361-803xlinking), 1999 Jul; 173(1): 25-29.
Impact Factor: 2.307
View Export to BibTeX Export to EndNote
Maurea S, Mainolfi C, Bazzicalupo L, Panico M, Imparato C, Alfano B, Ziviello M, Salvatore M
Characterization of adrenal tumors using F-18 FDG PET imaging: Comparison between benign and malignant lesions (440 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 May; 38(5SUPPL.): 25-29.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Papa V, Reese CC, Brunetti A, Vigneri R, Siiteri PK, Goldfine ID
Progestins increase insulin receptor content and insulin stimulation of growth in human breast carcinoma cells (442 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1990 Dec 15; 50(24): 7858-7862.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
* Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity (462 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015 Jan; 142: 39-46.
Impact Factor: 3.205
View Export to BibTeX Export to EndNote
Dynkevich Y, Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J
* Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive (1669 views)
Endocrine Reviews (ISSN: 0163-769x), 2013 Dec; 34(6): 798-826.
Impact Factor: 19.358
View Export to BibTeX Export to EndNote
De Rosa A, Rinaldi C, Tucci T, Pappata S, Rossi F, Morra VB, Faggiano A, Colao A, De Michele G
* Co-existence of primary hyperparathyroidism and Parkinson's disease in three patients: An incidental finding? (379 views)
Parkinsonism Relat D (ISSN: 1353-8020, 1873-5126, 1873-5126electronic), 2011 Dec; 17(10): 771-773.
Impact Factor: 3.795
View Export to BibTeX Export to EndNote
Maurea S, Imbriaco M, Mollica C, Pace L, Salvatore M
* Quantitative Imaging Characterization Of Hypersecreting Or Non-Hypersecreting Adrenal Adenomas: Comparison Between Iodine-131 Nor-Cholesterol Uptake And Magnetic Resonance Signal Intensity Ratios (284 views)
Nuclear Medicine Communications (ISSN: 1473-5628, 0143-3636), 2011 Jun; 32(6): 535-541.
Impact Factor: 1.404
View Export to BibTeX Export to EndNote
Maurea S, Soricelli A, Salvatore M
* Characterization of hypersecreting or non-hypersecreting adrenal adenomas: Comparison between iodine-131 nor-cholesterol scintigraphy and magnetic resonance imaging (315 views) (PDF 247 views)
Curr Radiopharm (ISSN: 1874-4710, 1874-4729), 2009; 2(1): 56-62.
Impact Factor: 0.643
View Export to BibTeX Export to EndNote
De Leva MF, Varrone A, Filla A, Quarantelli M, Bilo L, Piscitelli V, Salvatore E, Ammendola S, Striano S, De Michele G, Bonavita V, Pappata S
* Neuroimaging follow-up in a case of Rasmussen's encephalitis with dyskinesias (322 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2007 Oct 31; 22(14): 2117-2121.
Impact Factor: 3.207
View Export to BibTeX Export to EndNote
Tauchmanova L, Pivonello R, De Martino MC, Rusciano A, De Leo M, Ruosi C, Mainolfi C, Lombardi G, Salvatore M, Colao A
* Effects of sex steroids on bone in women with subclinical or overt endogenous hypercortisolism (368 views)
Eur J Endocrinol (ISSN: 0804-4643), 2007 Sep; 157(3): 359-366.
Impact Factor: 3.239
View Export to BibTeX Export to EndNote
Maurea S, Imbriaco M, D'Angelillo M, Mollica C, Camera L, Salvatore M
* Diagnostic accuracy of chemical-shift MR imaging to differentiate between adrenal adenomas and non adenoma adrenal lesions (327 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Sep; 111(5): 674-686.
Impact Factor: 1.368
View Export to BibTeX Export to EndNote
Tauchmanovà L, Colao A, Marzano LA, Sparano L, Camera L, Rossi A, Palmieri G, Marzano E, Salvatore M, Pettinato G, Lombardi G, Rossi R
* Andrenocortical carcinomas: Twelve-year prospective experience (294 views)
World J Surg (ISSN: 0364-2313), 2004 Sep; 28(9): 896-903.
Impact Factor: 1.952
View Export to BibTeX Export to EndNote
Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (349 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (459 views)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
Impact Factor: 2.767
View Export to BibTeX Export to EndNote
Maurea S, Klain M, Mainolfi C, Ziviello M, Salvatore M
* The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses (269 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2001 Jun; 42(6): 884-892.
Impact Factor: 4.51
View Export to BibTeX Export to EndNote
Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Nicolai E, Lucci R, Salvatore M, Lombardi G
Impaired cardiac performance in elderly patients with growth hormone deficiency (344 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1999 Nov; 84(11): 3950-3955.
Impact Factor: 5.805
View Export to BibTeX Export to EndNote
Maurea S, Mainolfi C, Bazzicalupo L, Panico MR, Imparato C, Alfano B, Ziviello M, Salvatore M
Imaging of adrenal tumors using FDG PET: comparison of benign and malignant lesions (355 views) (PDF 247 views)
Ajr Am J Roentgenol (ISSN: 0361-803x, 0361-803xlinking), 1999 Jul; 173(1): 25-29.
Impact Factor: 2.307
View Export to BibTeX Export to EndNote
Maurea S, Mainolfi C, Bazzicalupo L, Panico M, Imparato C, Alfano B, Ziviello M, Salvatore M
Characterization of adrenal tumors using F-18 FDG PET imaging: Comparison between benign and malignant lesions (440 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 May; 38(5SUPPL.): 25-29.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Papa V, Reese CC, Brunetti A, Vigneri R, Siiteri PK, Goldfine ID
Progestins increase insulin receptor content and insulin stimulation of growth in human breast carcinoma cells (442 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1990 Dec 15; 50(24): 7858-7862.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
16 Records (16 excluding Abstracts).
Total impact factor: 67.201 (67.201 excluding Abstracts).
Total 5 year impact factor: 77.44 (77.44 excluding Abstracts).
Total impact factor: 67.201 (67.201 excluding Abstracts).
Total 5 year impact factor: 77.44 (77.44 excluding Abstracts).
356 views. Last view on Monday 27 March 2023, 11:47:26
ibb.cnr.it
