Sorafenib in advanced iodine-refractory differentiated thyroid cancer: Efficacy, safety and exploratory analysis of role of serum thyroglobulin and FDG-PET
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Sorafenib in advanced iodine-refractory differentiated thyroid cancer: Efficacy, safety and exploratory analysis of role of serum thyroglobulin and FDG-PET (460 views)

Marotta V, Ramundo V, Camera L, Del Prete M, Fonti R, Esposito R, Palmieri G, Salvatore M, Vitale M, Colao A, Faggiano A

Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2013 May; 78(5): 760-767.

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Paper type: Research Support, Non-U. S. Gov'T, Book Chapter, Journal Article,

Impact factor: 3.353, 5-year impact factor: 3.198

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84876102913&partnerID=40&md5=00548ada3b2ac9f4963b3a074c942a37

Keywords: Fluorodeoxyglucose, Radioactive Iodine, Sorafenib, Thyroglobulin, Thyroglobulin Antibody, Thyroxine, Adult, Advanced Cancer, Alopecia, Article, Clinical Article, Diarrhea, Differentiated Thyroid Cancer, Drug Efficacy, Drug Safety, Drug Tolerability, Fatigue, Female, Hand Foot Syndrome, Human, Hypocalcemia, Overall Survival, Positron Emission Tomography, Priority Journal, Progression Free Survival, Side Effect, Skin Disease, Stomatitis, Thyroglobulin Blood Level, Treatment Response, Weight Reduction, Antineoplastic Agents, Fluorodeoxyglucose F18, Middle Aged, Niacinamide, Phenylurea Compounds, Positron-Emission Tomography, Retrospective Studies, Thyroid Neoplasms, Treatment Outcome, Braf, Gene Rearrangement, Ntrk1, Oncogenes, Pdtc, Pi3k, Antineoplastic Agents Adverse Effects Therapeutic Use , Niacinamide Adverse Effects Analogs, Derivatives Therapeutic Use , Phenylurea Compounds Adverse Effects Therapeutic Use , Positron-Emission Tomography Methods , Thyroid Neoplasms Blood Drug Therapy,

Affiliations:
*** IBB - CNR ***

Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Via S. Pansini 5, 80131 Napoli, Italy
Department of Biomorphological and Functional Sciences, Federico II University of Naples, Naples, Italy
Department of Medicine and Surgery, University of Salerno, Baronissi, Italy
National Cancer Institute, Fondazione G. Pascale, Naples, Italy
Molecular Mechanisms Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
Scientific Directorate, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy


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Sorafenib in advanced iodine-refractory differentiated thyroid cancer: Efficacy, safety and exploratory analysis of role of serum thyroglobulin and FDG-PET

Context Radioactive iodine is a crucial tool for treatment of differentiated thyroid cancer (DTC). In 5% of cases, DTCs lose I-131 avidity and assume an aggressive behaviour. Treatment options for iodine-refractory DTC are limited. We report the experience of off-label use of the tyrosine kinase inhibitor sorafenib for treatment of advanced iodine-refractory DTC. Design Patients with progressive DTC refractory to radioactive iodine were treated with sorafenib used off-label independently from their performance status. Primary study end-points were radiological response, progression-free survival (PFS) and safety. Secondary end-points were site-specific radiological response and overall survival (OS). An exploratory analysis of the role of serum thyroglobulin (Tg) and fluorodeoxyglucose (FDG) positron emission tomography (PET) was performed. Results A total of 17 patients were included in the study. Median follow-up was 15·5 months. Clinical benefit was obtained in 71% of subjects (30% partial response and 41% stable disease). Sorafenib was mostly well tolerated, but a high incidence of fatal events was reported (three patients died from severe bleeding events and two from cardiac arrest). Median PFS was 9 months. Median OS was 10 months. The best responses were observed in lymph nodes and lung. Baseline Tg levels and the Tg response to treatment were correlated to both radiological response and PFS. Baseline FDG-PET assessment and early FDG-PET response were correlated to radiological response. Conclusions Sorafenib allows morphological disease control in the majority of patients with iodine-refractory DTC. Progression-free survival and overall survival were lower than in previous studies as a consequence of the worse clinical condition of our patients. Sorafenib is mostly well tolerated but could have been responsible for the reported fatal events. Baseline Tg and the Tg response to treatment could be useful for predicting morphological response and clinical outcome. Early FDG-PET response could be helpful for the timely identification of nonresponding patients. © 2012 Blackwell Publishing Ltd.
Sorafenib in advanced iodine-refractory differentiated thyroid cancer: Efficacy, safety and exploratory analysis of role of serum thyroglobulin and FDG-PET

▼    High-resolution positron emission tomography of the ischaemic mouse heart
Sorafenib in advanced iodine-refractory differentiated thyroid cancer: Efficacy, safety and exploratory analysis of role of serum thyroglobulin and FDG-PET

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D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S
* A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients (441 views)
Int J Cancer (ISSN: 0020-7136), 2014 Jul 15; 135(2): 379-390.
Impact Factor: 5.085
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Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (546 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
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Petretta M, Petretta A, Pellegrino T, Nappi C, Cantoni V, Cuocolo A
* Nuclear Cardiology in Heart Failure (382 views)
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), 2014 Jan; 7(3): 1-7.
Impact Factor: 0
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Testi S, Peluso S, Fabrizi GM, Antenora A, Russo CV, Pappata S, Padovani A, Ferrarini M, Filla A
* A novel PSEN1 mutation in a patient with sporadic early-onset Alzheimer's disease and prominent cerebellar ataxia (289 views)
J Alzheimers Dis (ISSN: 1387-2877, 1387-2877linking), 2014; 41(3): 709-714.
Impact Factor: 4.151
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Molino I, Cavaliere C, Salvatore E, Quarantelli M, Colucci L, Fasanaro AM
* Is anterior communicating artery syndrome related to fornix lesions? (291 views)
J Alzheimers Dis (ISSN: 1387-2877, 1387-2877linking), 2014; 42Suppl3: S199-S199.
Impact Factor: 4.151
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Dubbioso R, Pappata S, Quarantelli M, D'Arco F, Manganelli F, Esposito M, Santoro L
* Atypical Clinical And Radiological Presentation Of Cryptococcal Choroid Plexitis In An Immunocompetent Woman (380 views)
J Neurol Sci (ISSN: 1878-5883, 0022-510x), 2013 Nov; 334(1-2): 180-182.
Impact Factor: 1.453
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Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
* Should patients with remnants from thyroid microcarcinoma really not be treated with iodine-131 ablation? (432 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Oct; 44(2): 426-433.
Impact Factor: 3.527
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Giacomobono S, Gallicchio R, Capacchione D, Nardelli A, Gattozzi D, Lettini G, Molinari L, Mainenti P, Cammarota A, Storto G
* F-18 FDG PET/CT in the assessment of patients with unexplained CEA rise after surgical curative resection for colorectal cancer (301 views)
International Journal Of Colorectal Disease (ISSN: 0179-1958, 0179-1958linking), 2013 Jul 12; 28(12): 1699-1705.
Impact Factor: 2.415
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Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (489 views)
J Clin Endocrinol Metab (ISSN: 1945-7197, 0021-972x, 0021-972xlinking), 2013 Mar; 98(3): 1214-1218.
Impact Factor: 6.31
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Greco A, Fiumara G, Gargiulo S, Gramanzini M, Brunetti A, Cuocolo A
* High-resolution positron emission tomography/computed tomography imaging of the mouse heart (467 views)
Exp Physiol Experimental Physiology (ISSN: 1469-445x, 0958-0670), 2013 Mar; 98(3): 645-651.
Impact Factor: 2.871
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De Luca S, Fonti R, Palmieri G, Federico P, Del Prete G, Pacelli R, Pace L, De Placido S, Salvatore M, Del Vecchio S
* Combined Imaging With 18f-Fdg-Pet/Ct And 111in-Labeled Octreotide Spect For Evaluation Of Thymic Epithelial Tumors (354 views)
Clin Nucl Med (ISSN: 1536-0229, 0363-3976, 0363-9762), 2013; 38(5): 354-358.
Impact Factor: 2.857
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Fonti R, Larobina M, Del Vecchio S, Fabbricini R, Catalano L, Pane F, Salvatore M, Pace L
* Metabolic tumor volume assessed by 18F-FDG PET/CT for the prediction of outcome in patients with multiple myeloma (587 views)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2012 Dec; 53(12): 1829-1835.
Impact Factor: 5.774
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Pascual B, Prieto E, Arbizu J, Marti-climent JM, Penuelas I, Quincoces G, Zarauza R, Pappata S, Masdeu JC
* Decreased carbon-11-flumazenil binding in early Alzheimer's disease (405 views) (PDF 259 views)
Brain (ISSN: 0006-8950, 1460-2156electronic, 0006-8950linking), 2012 Sep; 135(Pt9): 2817-2825.
Impact Factor: 9.915
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Iiritano S, Chiefari E, Ventura V, Arcidiacono B, Possidente K, Nocera A, Nevolo MT, Fedele M, Greco A, Greco M, Brunetti G, Fusco A, Foti D, Brunetti A
* The HMGA1-IGF-I/IGFBP system: a novel pathway for modulating glucose uptake (705 views)
Molecular Endocrinology (ISSN: 0888-8809, 1944-9917electronic), 2012 Sep; 26(9): 1578-1589.
Impact Factor: 4.746
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Mainenti PP, Iodice D, Cozzolino I, Segreto S, Capece S, Sica G, Magliulo M, Ciancia G, Pace L, Salvatore M
* Tomographic imaging of the spleen: the role of morphological and metabolic features in differentiating benign from malignant diseases (296 views)
Clin Imaging (ISSN: 1873-4499, 0899-7071, 0899-7071linking), 2012 Sep; 36(5): 559-567.
Impact Factor: 0.648
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Greco A, Petretta MP, Larobina M, Gargiulo S, Panico M, Nekolla SG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Reproducibility and accuracy of non-invasive measurement of infarct size in mice with high-resolution PET/CT (483 views)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2012 Jun; 19(3): 492-499.
Impact Factor: 2.847
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Pier PM
* RE: Imaging Features of Hepato-Splenic Amyloidosis at PET/CT (295 views)
Korean Journal Of Radiology (ISSN: 1229-6929), 2012 May; 13(3): 368-369.
Impact Factor: 1.555
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Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (493 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
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Gargiulo S, Greco A, Gramanzini M, Petretta MP, Ferro A, Larobina M, Panico M, Brunetti A, Cuocolo A
* PET/CT imaging in mouse models of myocardial ischemia (668 views)
J Biomed Biotechnol (ISSN: 1110-7251, 1110-7243), 2012; 2012: 541872-541872.
Impact Factor: 2.88
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Fragassi NA, Chiacchio L, Errichiello L, Pappata S, Tedeschi MR, Striano P, Striano S
* Posterior cortical atrophy with prominent alexia without agraphia in a Tourette syndrome (492 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Dec; 32(6): 1129-1133.
Impact Factor: 1.315
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
* Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism (491 views)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Impact Factor: 8.312
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Pace L, Nicolai E, D'Amico D, Ibello F, Della Morte AM, Salvatore B, Pizzuti LM, Salvatore M, Soricelli A
* Determinants of physiologic 18F-FDG uptake in brown adipose tissue in sequential PET/CT examinations (462 views)
Molecular Imaging And Biology (ISSN: 1860-2002, 1536-1632), 2011 Oct; 13(5): 1029-1035.
Impact Factor: 3.844
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Erro R, Amboni M, Vitale C, Longo K, Rocco M, Russo C, Pappata S, Brunetti A, Barone P
* The "eye of the tiger" sign in pure akinesia with gait freezing (317 views) (PDF 222 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Sep; 32(4): 703-705.
Impact Factor: 1.315
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Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (466 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
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Striano P, Caranci F, Pappata S, Zara F, Striano S
* Hemidystonia in uncontrolled type 2 diabetes mellitus (291 views)
Arch Neurol (ISSN: 1538-3687electronic, 0003-9942linking), 2011 May; 68(5): 674-675.
Impact Factor: 7.584
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Perrone-filardi P, Dellegrottaglie S, Rudd JH, Costanzo P, Marciano C, Vassallo E, Marsico F, Ruggiero D, Petretta MP, Chiariello M, Cuocolo A
* Molecular imaging of atherosclerosis in translational medicine (756 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 May; 38(5): 969-975.
Impact Factor: 4.991
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Esmaeilzadeh M, Kullingsjo J, Ullman H, Varrone A, Tedroff J
* Regional cerebral glucose metabolism after pridopidine (ACR16) treatment in patients with huntington disease (375 views)
Clin Neuropharmacol (ISSN: 0362-5664), 2011 May; 34(3): 95-100.
Impact Factor: 2.166
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Mainenti PP, Iodice D, Segreto S, Storto G, Magliulo M, De Palma GD, Salvatore M, Pace L
* Colorectal cancer and 18FDG-PET/CT: what about adding the T to the N parameter in loco-regional staging? (334 views)
World J Gastroentero (ISSN: 2219-2840, 1007-9327, 1007-9327linking), 2011 Mar 21; 17(11): 1427-1433.
Impact Factor: 2.471
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Storto G, Di Giorgio E, De Renzo A, Pizzuti LM, Cerciello G, Nardelli A, Capacchione D, Castaldi E, Ortosecco G, Pace L
* Assessment of metabolic activity by PET-CT with F-18-FDG in patients with T-cell lymphoma (531 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2010 Oct; 151(2): 195-197.
Impact Factor: 4.942
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Mainenti PP, Mancini M, Mainolfi C, Camera L, Maurea S, Manchia A, Tanga M, Persico F, Addeo P, D'Antonio D, Speranza A, Bucci L, Persico G, Pace L, Salvatore M
* Detection of colo-rectal liver metastases: Prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1. 5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (445 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2010 Oct; 35(5): 511-521.
Impact Factor: 1.95
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Orditura M, Galizia G, Napolitano V, Martinelli E, Pacelli R, Lieto E, Aurilio G, Vecchione L, Morgillo F, Catalano G, Ciardiello F, Del Genio A, Di Martino N, De Vita F
* Weekly Chemotherapy with Cisplatin and Paclitaxel and Concurrent Radiation Therapy as Preoperative Treatment in Locally Advanced Esophageal Cancer: A Phase II Study (351 views)
Cancer Investigation (ISSN: 0735-7907), 2010 Oct; 28(8): 820-827.
Impact Factor: 2.39
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Salvatore E, Di Maio L, Filla A, Ferrara AM, Rinaldi C, Sacca F, Peluso S, Macchia PE, Pappata S, De Michele G
* Benign hereditary chorea: Clinical and neuroimaging features in an Italian family (356 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2010 Jul 30; 25(10): 1491-1496.
Impact Factor: 4.48
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Di Lorenzo G, Imbimbo M, Leopardo D, Marciano R, Federico P, Buonerba C, Salvatore B, Marinelli A, Palmieri G. A
* A long-lasting response to sorafenib treatment in an advanced hepatocellular carcinoma patient (296 views)
Int J Immunopathol Pharmacol (ISSN: 0394-6320), 2010 Jul; 23(3): 951-954.
Impact Factor: 2.685
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (621 views)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
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Mainenti PP, Segreto S, Mancini M, Rispo A, Cozzolino I, Masone S, Rinaldi CR, Nardone G, Salvatore M
* Intestinal amyloidosis: two cases with different patterns of clinical and imaging presentation (386 views)
World J Gastroentero (ISSN: 2219-2840, 1007-9327, 1007-9327linking), 2010 May 28; 16(20): 2566-2570.
Impact Factor: 2.24
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Bilo L, Meo R, de Leva MF, Vicidomini C, Salvatore M, Pappata S
* Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: a case report (534 views)
Seizure (ISSN: 1532-2688, 1059-1311), 2010 Apr; 19(3): 198-201.
Impact Factor: 1.649
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Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, Tomaino C, Muraca MG, Leotta A, Lio SG, Pinessi L, Rainero I, Sorbi S, Nee L, Milan G, Pappata S, Postiglione A, Abbamondi N, Forloni G, St George Hyslop P, Rogaeva E, Bugiani O, Giaccone G, Foncin JF, Spillantini MG, Puccio G
* Worldwide distribution of PSEN1 Met146Leu mutation: A large variability for a founder mutation (972 views)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2010 Mar 9; 74(10): 798-806.
Impact Factor: 8.017
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Caprio MG, Cangiano A, Imbriaco M, Soscia F, Di Martino G, Farina A, Avitabile G, Pace L, Forestieri P, Salvatore M
* Dual-time-point [18F]-FDG PET/CT in the diagnostic evaluation of suspicious breast lesions (509 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2010 Mar; 115(2): 215-224.
Impact Factor: 1.618
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
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Cuocolo A, Breatnach E
* Multimodality imaging in Europe: a survey by the European Association of Nuclear Medicine (EANM) and the European Society of Radiology (ESR) (460 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2010 Jan; 37(1): 163-167.
Impact Factor: 5.036
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Varrone A, Asenbaum S, Vander Borght T, Booij J, Nobili F, Någren K, Darcourt J, Kapucu OL, Tatsch K, Bartenstein P, Van Laere K
* EANM procedure guidelines for PET brain imaging using [18F]FDG, version (635 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Dec; 36(12): 2103-2110.
Impact Factor: 4.531
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (287 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2009 Dec; 114(8): 1385-1385.
Impact Factor: 1.454
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Lucignani G, Cuocolo A
Recent advances in the assessment of myocardial viability (396 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2009 Nov; 36(11): 1892-1895.
Impact Factor: 4.531
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Criscuolo C, Filla A, Coppola G, Rinaldi C, Carbone R, Pinto S, Wang Q, De Leva MF, Salvatore E, Banfi S, Brunetti A, Quarantelli M, Geschwind DH, Pappata S, De Michele G
* Two novel CYP7B1 mutations in Italian families with SPG5: A clinical and genetic study (359 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2009 Sep; 256(8): 1252-1257.
Impact Factor: 2.903
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Imbriaco M, Pisani A, Spinelli L, Cuocolo A, Messalli G, Capuano E, Marmo M, Liuzzi R, Visciano B, Cianciaruso B, Salvatore M
* Effects of enzyme-replacement therapy in patients with Anderson-Fabry disease: a prospective long-term cardiac magnetic resonance imaging study (526 views)
Heart (ISSN: 1355-6037, 1468-201x), 2009 Jul; 95(13): 1103-1107.
Impact Factor: 5.385
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Storto G, Nicolai E, Salvatore M
* [18F]FDG-PET-CT for early monitoring of tumor response: When and why (372 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009 Apr; 53(2): 167-180.
Impact Factor: 1.724
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De Rosa A, Criscuolo C, Mancini P, De Martino M, Giordano IA, Pappata S, Filla A, De Michele G
* Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy (257 views)
Parkinsonism Relat D (ISSN: 1353-8020print, 1353-8020linking, 1873-5126electronic), 2009 Mar; 15(3): 242-244.
Impact Factor: 2.406
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Pace L, Nicolai E, Klain M, Salvatore M
* Diagnostic value of FDG PET/CT imaging (396 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009; 53(5): 503-512.
Impact Factor: 1.724
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Imbriaco M, Caprio MG, Limite G, Pace L, De Falco T, Capuano E, Salvatore M
* Dual-time-point 18F-FDG PET/CT versus dynamic breast MRI of suspicious breast lesions (296 views)
Ajr Am J Roentgenol (ISSN: 1546-3141, 0361-803x, 1546-3141electronic), 2008 Nov; 191(5): 1323-1330.
Impact Factor: 2.94
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Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (618 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
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Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (368 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (334 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2008 Mar; 113(2): 278-288.
Impact Factor: 0.955
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Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (549 views)
J Nucl Med (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.
Impact Factor: 6.662
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De Leva MF, Varrone A, Filla A, Quarantelli M, Bilo L, Piscitelli V, Salvatore E, Ammendola S, Striano S, De Michele G, Bonavita V, Pappata S
* Neuroimaging follow-up in a case of Rasmussen's encephalitis with dyskinesias (339 views)
Mov Disord (ISSN: 0885-3185, 1531-8257, 0885-3185linking), 2007 Oct 31; 22(14): 2117-2121.
Impact Factor: 3.207
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Mainenti PP, Salvatore B, Sirignano C, De Falco T, Speranza A, Fiumara G, Ricci F, Evangelista L, Pace L, Salvatore M
* PET/CT colonography in patients with colo-rectal polyps: A feasibility study (292 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34(10): 1594-1603.
Impact Factor: 4.101
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Picardi M, De Renzo A, Pane F, Nicolai E, Pacelli R, Salvatore M, Rotoli B
* Randomized comparison of consolidation radiation versus observation in bulky Hodgkin's lymphoma with post-chemotherapy negative positron emission tomography scans (395 views)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2007 Sep; 48(9): 1721-1727.
Impact Factor: 1.512
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Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (617 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (416 views)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Sorrentino AR, Acampa W, Petretta M, Mainolfi C, Salvatore M, Cuocolo A
* Comparison of the prognostic value of SPECT after nitrate administration and metabolic imaging by PET in patients with ischaemic left ventricular dysfunction (337 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Apr; 34(4): 558-562.
Impact Factor: 4.101
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Del Giudice E, Bianchi MC, Tosetti M, Varrone A, Romano A, Crisanti AF, Titomanlio L, Imperati F
* Taylor-type focal cortical dysplasia: is the epilepsy always resistant to medical treatment? (328 views)
Epileptic Disord (ISSN: 1294-9361), 2006 Dec; 8(4): 289-293.
Impact Factor: 1.202
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Seneca N, Gulyas B, Varrone A, Schou M, Airaksinen A, Tauscher J, Vandenhende F, Kielbasa W, Farde L, Innis R, Halldin C
* Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: A PET study in nonhuman primate brain using (S, S)-[18F] FMeNER-D2 (431 views)
Psychopharmacology (ISSN: 0033-3158), 2006 Sep; 188(1): 119-127.
Impact Factor: 3.625
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Berkouk K, Quarantelli M, Prinster A, Landeau B, Alfano B, Baron JC
* Mapping The Relative Contribution Of Gray Matter Activity Versus Volume In Brain Pet. A New Approach (390 views) (PDF 231 views)
J Neuroimaging (ISSN: 1051-2284, 1051-2284linking), 2006 Jul; 16(3): 224-235.
Impact Factor: 1.298
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De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
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Cuocolo A, Acampa W, Varrone A, Salvatore M
* Highlights of the Annual Congress of the European Association of Nuclear Medicine, Istanbul, 2005: The incremental value of nuclear medicine for patient management and care (585 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Mar; 33(3): 360-381.
Impact Factor: 4.041
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Pace L, Klain M, Albanese C, Salvatore B, Storto G, Soricelli A, Salvatore M
* Short-term outcome of differentiated thyroid cancer patients receiving a second iodine-131 therapy on the basis of a detectable serum thyroglobulin level after initial treatment (396 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Feb; 33(2): 179-183.
Impact Factor: 4.041
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Pace L, Klain M, Soricelli A, Albanese C, Salvatore B, Storto G, Salvatore M
* Short Term Outcome of Differentiated Thyroid Cancer Patients with Detectable Serum Thyroglobulin after Initial Treatment Receiving a Second 131-IODINE Therapy (335 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: 179-183.
Impact Factor: 3.883
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Cuocolo A
FDG imaging should be considered the preferred technique for accurate assessment of myocardial viability: against (268 views)
Eur J Nucl Med (ISSN: 1619-7070print, 1619-7070linking, 1619-7089electronic), 2005 Jul; 32(7): 832-835.
Impact Factor: 3.883
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Quarantelli M, Berkouk K, Prinster A, Landeau B, Svarer C, Balkay L, Alfano B, Brunetti A, Baron JC, Salvatore M
* Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction (557 views) (PDF 259 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2004 Feb; 45(2): 192-201.
Impact Factor: 5.362
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Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (351 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
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He W, Acampa W, Mainolfi C, Menna F, Sorrentino AR, Petretta M, Cuocolo A
* Tc-99m tetrofosmin tomography after nitrate administration in patients with ischemic left ventricular dysfunction: Relation to metabolic imaging by PET (379 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2003 Nov; 10(6): 599-606.
Impact Factor: 1.629
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (280 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Cuocolo A, Acampa W, Evangelista L
* Nuclear medicine and positron emission tomography imaging in cardiology (401 views)
Nucl Med Rev (ISSN: 1506-9680), 2003; 6(1): 59-63.
Impact Factor: 0.155
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Salvatore M, Fonti R
* New frontiers of nuclear medicine (457 views)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 2002 May; 88(3): S60-S60.
Impact Factor: 0.267
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Zingone A, Seidel J, Aloj L, Caraco C, Vaquero JJ, Jagoda EM, Chou JY, Green MV, Eckelman WC
* Monitoring the correction of glycogen storage disease type 1a in a mouse model using [18F]FDG and a dedicated animal scanner (267 views)
Life Sci (ISSN: 0024-3205), 2002; 71(11): 1293-1301.
Impact Factor: 1.824
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Danforth Dn JR, Aloj L, Carrasquillo JA, Bacharach SL, Chow C, Zujewski J, Whatley M, Galen B, Merino M, Neumann RD
* The role of 18F-FDG-PET in the local/regional evaluation of women with breast cancer (276 views)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 2002; 75(2): 135-146.
Impact Factor: 3.132
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Acampa W, Petretta M, Cuocolo A
* Myocardial viability assessment in regions of left ventricular dysfunction. Part II: The present and future of echocardiography and magnetic resonance imaging (254 views)
Nuclear Medicine Communications (ISSN: 0143-3636, 1473-5628), 2001 Jul; 22(7): 731-735.
Impact Factor: 1.19
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Petretta M, Acampa W, Cuocolo A
* Myocardial viability assessment in regions of left ventricular dysfunction. Part I: Radionuclide imaging and clinical implications (347 views)
Nuclear Medicine Communications (ISSN: 0143-3636, 1473-5628), 2001 Jun; 22(6): 607-611.
Impact Factor: 1.19
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Cuocolo A, Acampa W
* Nuclear cardiology in the new millennium (324 views)
Rev Esp Med Nucl (ISSN: 0212-6982), 2001 Jun; 20(4): 305-308.
Impact Factor: 0.155
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Maurea S, Klain M, Mainolfi C, Ziviello M, Salvatore M
* The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses (272 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2001 Jun; 42(6): 884-892.
Impact Factor: 4.51
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Maurea S, Mainolfi C, Bazzicalupo L, Panico MR, Imparato C, Alfano B, Ziviello M, Salvatore M
Imaging of adrenal tumors using FDG PET: comparison of benign and malignant lesions (360 views) (PDF 247 views)
Ajr Am J Roentgenol (ISSN: 0361-803x, 0361-803xlinking), 1999 Jul; 173(1): 25-29.
Impact Factor: 2.307
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Del Vecchio S, Ciarmiello A, Salvatore M
Clinical imaging of multidrug resistance in cancer (361 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1999 Jun; 43(2): 125-131.
Impact Factor: 2.125
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (394 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Ferone D, Lastoria S, Colao A, Varrella P, Cerbone G, Acampa W, Merola B, Salvatore M, Lombardi G
Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas (324 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1998 Jan; 83(1): 248-252.
Impact Factor: 5.641
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Mainolfi C, Maurea S, Varrella P, Alaia C, Imparato C, Alfano B, Abate G, Bazzicalupo L
Positron-emission tomography with fluorine-18-deoxyglucose in the staging and control of patients with lymphoma. Comparison with clinico-radiologic assessment (310 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1998 Jan; 95(1-2): 98-104.
Impact Factor: 0.967
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Mainolfi C, Maurea S, Varrella P, Alaia C, Imparato C, Alfano B, Abate G, Bazzicalupo L
18-FDG PET in the staging and follow-up of lymphoma patients: Comparison with clinical and radiologic findings (330 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 1998; 95(1-2): 98-104.
Impact Factor: 0.967
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Maurea S, Mainolfi C, Bazzicalupo L, Panico M, Imparato C, Alfano B, Ziviello M, Salvatore M
Characterization of adrenal tumors using F-18 FDG PET imaging: Comparison between benign and malignant lesions (440 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 May; 38(5SUPPL.): 25-29.
Impact Factor: 3.491
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Postiglione A, Soricelli, Salvatore M, Lassen NA
123I-iomazenil as a clinical tool for studying neuronal loss [4] (340 views)
J Am Geriatr Soc (ISSN: 0002-8614), 1997 Apr; 45(4): 534-536.
Impact Factor: 2.806
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Wang H, Maurea S, Mainolfi C, Fiore F, Gravina A, Panico M, Bazzicalupo L, Salvatore M
Tc-99m MIBI scintigraphy in patients with lung cancer comparison with CT and fluorine-18 FDG PET imaging (321 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1997 Apr; 22(4): 243-249.
Impact Factor: 0.34
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Brunetti A, Alfano B, Soricelli A, Tedeschi E, Mainolfi C, Covelli EM, Aloj L, Panico M, Bazzicalupo L, Salvatore M
Functional characterization of brain tumors: An overview of the potential clinical value (835 views) (PDF 245 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 699-715.
Impact Factor: 1.042
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Postiglione A, Soricelli A, Covelli EM, Iazzetta N, Ruocco A, Milan G, Santoro L, Alfano B, Brunetti A
Premature aging in Werner's syndrome spares the central nervous system (670 views) (PDF 210 views)
Neurobiol Aging (ISSN: 0197-4580, 1558-1497electronic, 0197-4580linking), 1996 May; 17(3): 325-330.
Impact Factor: 2.872
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Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (451 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (336 views)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Maurea S, Cuocolo A, Reynolds J, Keiser H, Neumann R, Salvatore M
Iodine-131 metaiodobenzylguanidine scintigraphy in the evaluation of paragangliomas. Comparison between benign and malignant tumors (252 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 87(5): 688-693.
Impact Factor: 0.967
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Maurea S, Maurelli L, Lastoria S, Cuocolo A, Brunetti A, Pace L, Caracò C, Klain M, Lupoli G, Salvatore M
Familial pheochromocytoma in Sipple's syndrome. A comparison between scintigraphy with 131I-meta-iodobenzylguanidine, computed tomography and echography (251 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 83(4): 486-490.
Impact Factor: 0.967
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Maurelli L, Cuocolo A, Lastoria S, Brunetti A, Maurea S, Lembo G, Klain M, Carac C, Salvatore M
131I-meta-iodobenzylguanidine scintigraphy in patients with a suspected pheochromocytoma. A comparison with CT and biohumoral parameters (487 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1991; 82(6): 839-843.
Impact Factor: 0.967
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Marchetti P, Benzi L, Trischitta V,  Brunetti A, Cecchetti P, Ciccarone AM, Pezzino V, Vigneri R, Navalesi R
Complementary use of gel permeation and reversed-phase liquid chromatography for the analysis of A14-[125I]insulin and its degradation products in isolated human monocytes (1719 views)
J Chromatogr B Biomed Sci Appl (ISSN: 0378-4347), 1986 Apr 25; 377(C): 339-344.
Impact Factor: 1.588
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Alfano B, Coucourde F, Malgieri F, Ragozzino A
PET/CT and radiotherapy (2833 views)
Q J Nucl Med Mol Imaging, 1980 Oct; 50(1): 4-14.
Impact Factor: 0
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123 Records (116 excluding Abstracts).
Total impact factor: 379.261 (358.359 excluding Abstracts).
Total 5 year impact factor: 391.338 (368.531 excluding Abstracts).

Last modified by Marco Comerci on Sunday 12 July 2020, 13:14:53
460 views. Last view on Sunday 28 May 2023, 9:52:38