Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy (405 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Dec; 20(12): 1186-1192.
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Paper type: Journal Article,
Impact factor: 2.692, 5-year impact factor: 3.983
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0027717554&partnerID=40&md5=4424fd8637f9e59fdd52c195c71727d9
Keywords: Chronic Coronary Artery Disease Correspondence To: A Cuocolo, Via Posillipo 66, I-80123 Napoli, Italy, Resting Cardiac Imaging, Technetium-99m Methoxyisobutylisonitrile, Thallium-201, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Thallium 201, Adult, Article, Clinical Article, Diagnostic Imaging, Exercise, Heart Ejection Fraction, Heart Left Ventricle Failure, Heart Muscle, Heart Scintiscanning, Human, Image Analysis, Intermethod Comparison, Intravenous Drug Administration, Chronic Disease, Comparative Study, Coronary Disease, Middle Age, Support, Non-U S Gov, Technetium Tc 99m Sestamibi, Thallium Radioisotopes,
Affiliations:
Department of Nuclear Medicine, University Federico II, Napoli, Italy
Department of Internal Medicine, University Federico II, Napoli, Italy
National Cancer Institute, Napoli, Italy
References:
Not available.
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Dec; 20(12): 1186-1192.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.692, 5-year impact factor: 3.983
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0027717554&partnerID=40&md5=4424fd8637f9e59fdd52c195c71727d9
Keywords: Chronic Coronary Artery Disease Correspondence To: A Cuocolo, Via Posillipo 66, I-80123 Napoli, Italy, Resting Cardiac Imaging, Technetium-99m Methoxyisobutylisonitrile, Thallium-201, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Thallium 201, Adult, Article, Clinical Article, Diagnostic Imaging, Exercise, Heart Ejection Fraction, Heart Left Ventricle Failure, Heart Muscle, Heart Scintiscanning, Human, Image Analysis, Intermethod Comparison, Intravenous Drug Administration, Chronic Disease, Comparative Study, Coronary Disease, Middle Age, Support, Non-U S Gov, Technetium Tc 99m Sestamibi, Thallium Radioisotopes,
Affiliations:
Department of Nuclear Medicine, University Federico II, Napoli, Italy
Department of Internal Medicine, University Federico II, Napoli, Italy
National Cancer Institute, Napoli, Italy
References:
Not available.
Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy
We studied 19 patients with angiographically proven coronary artery disease and left ventricular dysfunction (ejection fraction 33% ± 8%) by resting technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) and rest-redistribution thallium-201 cardiac imaging. Thallium and (99mTc-MIBI) studies were visually analysed. Of 285 segments, 203 (71%) had normal thallium uptake, 48 (17%) showed reversible thallium defects and 34 (12%) showed irreversible thallium defects. Of these 34 irreversible thallium defects, 19 (56%) were moderate and 15 (44%) were severe. Of the corresponding 285 segments, 200 (70%) had normal 99mTc-MIBI uptake, while 37 (13%) showed moderate and 48 (17%) showed severe reduction of 99 99mTc-MIBI uptake. Myocardial segmental agreement for regional uptake score between initial thallium and resting (99mTc-MIBI) images was 90% (κ=0.78). Segmental agreement between delayed thallium and resting 99Tc-MIBI images was 77% (κ=0.44). In particular, in 26 (9%) segments 99mTc-MIBI uptake was severely reduced while delayed thallium uptake was normal or only moderately reduced. These data suggest that although rest-redistribution thallium and resting (99mTc-MIBI) cardiac imaging provide concordant results in the majority of myocardial segments, some segments with severely reduced resting 99mTc-MIBI uptake may contain viable but hypoperfused myocardium. Thus, conclusions on myocardial viability based on 99mTc-MIBI uptake should be made with caution in chronic coronary artery disease. © 1993 Springer-Verlag.
We studied 19 patients with angiographically proven coronary artery disease and left ventricular dysfunction (ejection fraction 33% ± 8%) by resting technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) and rest-redistribution thallium-201 cardiac imaging. Thallium and (99mTc-MIBI) studies were visually analysed. Of 285 segments, 203 (71%) had normal thallium uptake, 48 (17%) showed reversible thallium defects and 34 (12%) showed irreversible thallium defects. Of these 34 irreversible thallium defects, 19 (56%) were moderate and 15 (44%) were severe. Of the corresponding 285 segments, 200 (70%) had normal 99mTc-MIBI uptake, while 37 (13%) showed moderate and 48 (17%) showed severe reduction of 99 99mTc-MIBI uptake. Myocardial segmental agreement for regional uptake score between initial thallium and resting (99mTc-MIBI) images was 90% (κ=0.78). Segmental agreement between delayed thallium and resting 99Tc-MIBI images was 77% (κ=0.44). In particular, in 26 (9%) segments 99mTc-MIBI uptake was severely reduced while delayed thallium uptake was normal or only moderately reduced. These data suggest that although rest-redistribution thallium and resting (99mTc-MIBI) cardiac imaging provide concordant results in the majority of myocardial segments, some segments with severely reduced resting 99mTc-MIBI uptake may contain viable but hypoperfused myocardium. Thus, conclusions on myocardial viability based on 99mTc-MIBI uptake should be made with caution in chronic coronary artery disease. © 1993 Springer-Verlag.
Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy
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Resting technetium-99m methoxyisobutylisonitrile cardiac imaging in chronic coronary artery disease: comparison with rest-redistribution thallium-201 scintigraphy
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Morisco C, Argenziano L, Salvatore M
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (358 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
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Maurea S, Cuocolo A, Pace L, Nicolai E, Nappi A, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Rest-injected thallium-201 redistribution and resting technetium-99m methoxyisobutylisonitrile uptake in coronary artery disease: relation to the severity of coronary artery stenosis (336 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Jun; 20(6): 502-510.
Impact Factor: 2.692
View Export to BibTeX Export to EndNote
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (358 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
View Export to BibTeX Export to EndNote
Maurea S, Cuocolo A, Pace L, Nicolai E, Nappi A, Imbriaco M, Morisco C, Chiariello M, Trimarco B, Salvatore M
Rest-injected thallium-201 redistribution and resting technetium-99m methoxyisobutylisonitrile uptake in coronary artery disease: relation to the severity of coronary artery stenosis (336 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1993 Jun; 20(6): 502-510.
Impact Factor: 2.692
View Export to BibTeX Export to EndNote
2 Records (2 excluding Abstracts).
Total impact factor: 5.384 (5.384 excluding Abstracts).
Total 5 year impact factor: 7.966 (7.966 excluding Abstracts).
Total impact factor: 5.384 (5.384 excluding Abstracts).
Total 5 year impact factor: 7.966 (7.966 excluding Abstracts).
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