Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings
Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings(386 views) Montella S, Santamaria F, Salvatore M, Maglione M, Iacotucci P, De Santi MM, Mollica C
Department of Paediatrics, University of Naples Federico II, Naples, Italy. santamar@unina.it.
Diagnostic Imaging, University of Naples Federico II, Naples, Italy
Department of Human Pathology and Oncology, University of Siena, Siena, Italy
Biostructure and Bioimaging Institute, National Research Council, Naples, Italy
IRCCS-SDN Foundation, Naples, Italy
References: Schidlow, D.V., Primary ciliary dyskinesia (the immotile cilia syndrome) (1994) Ann Allergy, 73, pp. 457-46
Afzelius, B.A., Cilia-related diseases (2004) J Pathol, 204, pp. 470-477
Bush, A., Chodhari, R., Collins, N., Copeland, F., Hall, P., Harcourt, J., Hariri, M., Phillips, G., Primary ciliary dyskinesia: Current state of the art (2007) Archives of Disease in Childhood, 92 (12), pp. 1136-1140. , DOI 10.1136/adc.2006.096958
Brody, A.S., Thoracic CT technique in children (2001) J Thorac Imaging, 16, pp. 259-268
Padley, S.P.G., Adler, B., Muller, N.L., High-resolution computed tomography of the chest: Current indications (1993) Journal of Thoracic Imaging, 8 (3), pp. 189-199
Brody, A.S., Frush, D.P., Huda, W., Brent, R.L., Dipietro, M.A., Applegate, K.E., Cassady, C.I., Stolic, A., Radiation risk to children from computed tomography (2007) Pediatrics, 120 (3), pp. 677-682. , http://pediatrics.aappublications.org/cgi/reprint/120/3/677, DOI 10.1542/peds.2007-1910
Brenner, D.J., Hall, E.J., Computed tomography - An increasing source of radiation exposure (2007) New England Journal of Medicine, 357 (22), pp. 2277-2284. , http://content.nejm.org/cgi/reprint/357/22/2277.pdf, DOI 10.1056/NEJMra072149
Hollis, D.P., Economou, J.S., Parks, L.C., Eggleston, J.C., Saryan, L.A., Czeister, J.L., Nuclear magnetic resonance studies of several experimental and human malignant tumors (1973) Cancer Res, 33, pp. 2156-2160
O'Donovan, P.B., Ross, J.S., Magnetic resonance of the pulmonary parenchyma: Initial experience at 0.6 Tesla (1986) CardioVascular and Interventional Radiology, 8 (5-6), pp. 300-305
Cohen, M.D., Eigen, H., Scott, P.H., Tepper, R., Cory, D.A., Smith, J.A., Scales, R.L., Magnetic resonance imaging of inflammatory lung disorders: Preliminary studies in children (1986) Pediatr Pulmonol, 2, pp. 211-217
Fiel, S.B., Friedman, A.C., Caroline, D.F., Magnetic resonance imaging in young adults with cystic fibrosis (1987) Chest, 91 (2), pp. 181-184
McFadden, R.G., Carr, T.J., Wood, T.E., Proton magnetic resonance imaging to stage activity of interstitial lung disease (1987) Chest, 92 (1), pp. 31-39
Mohiaddin, R.H., Notohamiprodjio, G., Schoser, K., Magnetic resonance imaging of lung signal intensity and dimensions in patients with advanced lung disease before and after single lung transplantation (1995) Eur J Radiol, 20, pp. 16-22
Puderbach, M., Kauczor, H.U., Assessment of lung function in children by cross-sectional imaging: Techniques and clinical applications (2006) Pediatr Radiol, 36, pp. 192-204
Puderbach, M., Eichinger, M., Gahr, J., Ley, S., Tuengerthal, S., Schmahl, A., Fink, C., Kauczor, H.-U., Proton MRI appearance of cystic fibrosis: Comparison to CT (2007) European Radiology, 17 (3), pp. 716-724. , DOI 10.1007/s00330-006-0373-4
Anjorin, A., Schmidt, H., Posselt, H.G., Smaczny, C., Ackermann, H., Deimling, M., Vogl, T.J., Abolmaali, N., Comparative evaluation of chest radiography, low-field MRI, the Shwachman-Kulczycki score and pulmonary function tests in patients with cystic fibrosis (2008) Eur Radiol, 18, pp. 1153-1161
Santamaria, F., Montella, S., Tiddens, H.A., Guidi, G., Casotti, V., Maglione, M., De Jong, P.A., Structural and functional lung disease in primary ciliary dyskinesia (2008) Chest, 134, pp. 351-357
Kennedy, M.P., Noone, P.G., Leigh, M.W., Zariwala, M.A., Minnix, S.L., Knowles, M.R., Molina, P.L., High-resolution CT of patients with primary ciliary dyskinesia (2007) American Journal of Roentgenology, 188 (5), pp. 1232-1238. , DOI 10.2214/AJR.06.0965
Jain, K., Padley, S.P.G., Goldstraw, E.J., Kidd, S.J., Hogg, C., Biggart, E., Bush, A., Primary ciliary dyskinesia in the paediatric population: Range and severity of radiological findings in a cohort of patients receiving tertiary care (2007) Clinical Radiology, 62 (10), pp. 986-993. , DOI 10.1016/j.crad.2007.04.015, PII S0009926007002085
Helbich, T.H., Heinz-Peer, G., Eichler, I., Wunderbaldinger, P., Gotz, M., Wojnarowski, C., Brasch, R.C., Herold, C.J., Cystic fibrosis: CT assessment of lung involvement in children and adults (1999) Radiology, 213 (2), pp. 537-544
ATS statement: Standardization of spirometry, 1994 update (1995) Am J Respir Crit Care Med, 152, pp. 1107-1136. , American Thoracic Society
Sahebjami, H., Gartside, P.S., Pulmonary function in obese subjects with a normal FEV1/FVC ratio (1996) Chest, 110, pp. 1425-1429
Ellerman, A., Bisgaard, H., Longitudinal study of lung function in a cohort of primary ciliary dyskinesia (1997) European Respiratory Journal, 10 (10), pp. 2376-2379. , DOI 10.1183/09031936.97.10102376
Pifferi, M., Caramella, D., Ragazzo, V., Pietrobelli, A., Boner, A.L., Low-density areas on high-resolution computed tomograms in chronic pediatric asthma (2002) Journal of Pediatrics, 141 (1), pp. 104-108. , DOI 10.1067/mpd.2002.125006
Müller, N.L., Computed tomography and magnetic resonance imaging: Past, present and future (2002) Eur Respir J, 19 (SUPPL. 35), pp. 3-12
Schertler, T., Lardinois, D., Boehm, T., Weder, W., Wildermuth, S., Alkadhi, H., Lung transplantation in Kartagener syndrome and situs inversus: Potential of multidetector row computed tomography and three-dimensional postprocessing (2007) Journal of Thoracic and Cardiovascular Surgery, 134 (3), pp. 814-815. , DOI 10.1016/j.jtcvs.2007.05.013, PII S0022522307008689
De Jong, P.A., Mayo, J.R., Golmohammadi, K., Nakano, Y., Lequin, M.H., Tiddens, H.A.W.M., Aldrich, J., Sin, D.D., Estimation of cancer mortality associated with repetitive computed tomography scanning (2006) American Journal of Respiratory and Critical Care Medicine, 173 (2), pp. 199-203. , http://ajrccm.atsjournals.org/cgi/reprint/173/2/199, DOI 10.1164/rccm.200505-810OC
Linet, M.S., Kim, K.P., Rajaraman, P., Children's exposure to diagnostic medical radiation and cancer risk: Epidemiologic and dosimetric considerations (2009) Pediatr Radiol, 39 (SUPPL. 1), pp. 4-26
(2005) Biological Effects of Ionizing Radiation (BEIR) VII: Health Risks from Exposure to Low Levels of Ionizing Radiation, , Committee on the Biological Effects of Ionizing Radiation. Washington DC
National Academies Press
Zapke, M., Topf, H.-G., Zenker, M., Kuth, R., Deimling, M., Kreisler, P., Rauh, M., Rupprecht, T., Magnetic resonance lung function - A breakthrough for lung imaging and functional assessment? a phantom study and clinical trial (2006) Respiratory Research, 7, p. 106. , http://respiratory-research.com/content/7/1/106, DOI 10.1186/1465-9921-7-106
Altes, T.A., Eichinger, M., Puderbach, M., Magnetic resonance imaging of the lung in cystic fibrosis (2007) Proceedings of the American Thoracic Society, 4 (4), pp. 321-327. , http://pats.atsjournals.org/cgi/reprint/4/4/321, DOI 10.1513/pats.200611-181HT
Lutterbey, G., Gieseke, J., Von Falkenhausen, M., Morakkabati, N., Schild, H., Lung MRI at 3.0 T: A comparison of helical CT and high-field MRI in the detection of diffuse lung disease (2005) Eur Radiol, 15, pp. 324-328
Machann, J., Schlemmer, H.-P., Schick, F., Technical challenges and opportunities of whole-body magnetic resonance imaging at 3 T (2008) Physica Medica, 24 (2), pp. 63-70. , DOI 10.1016/j.ejmp.2008.01.011, PII S1120179708000264
Yi, C.A., Shin, K.M., Lee, K.S., Kim, B.T., Kim, H., Kwon, O.J., Choi, J.Y., Chung, M.J., Non-small cell lung cancer staging: Efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging (2008) Radiology, 248, pp. 632-642
Heidemann, R.M., Griswold, M.A., Kiefer, B., Nittka, M., Wang, J., Jellus, V., Jakob, P.M., Resolution enhancement in lung1H imaging using parallel imaging methods (2003) Magnetic Resonance in Medicine, 49 (2), pp. 391-394. , DOI 10.1002/mrm.10349
Fink, C., Bock, M., Puderbach, M., Schmahl, A., Delorme, S., Partially parallel three-dimensional magnetic resonance imaging for the assessment of lung perfusion - Initial results (2003) Investigative Radiology, 38 (8), pp. 482-488. , DOI 10.1097/00004424-200308000-00002
Hirsch, W., Sorge, I., Krohmer, S., Weber, D., Meier, K., Till, H., MRI of the lungs in children (2008) Eur J Radiol, 68, pp. 278-288
Schidlow, D. V., Primary ciliary dyskinesia (the immotile cilia syndrome) (1994) Ann Allergy, 73, pp. 457-46
Afzelius, B. A., Cilia-related diseases (2004) J Pathol, 204, pp. 470-477
Brody, A. S., Thoracic CT technique in children (2001) J Thorac Imaging, 16, pp. 259-268
Padley, S. P. G., Adler, B., Muller, N. L., High-resolution computed tomography of the chest: Current indications (1993) Journal of Thoracic Imaging, 8 (3), pp. 189-199
Brody, A. S., Frush, D. P., Huda, W., Brent, R. L., Dipietro, M. A., Applegate, K. E., Cassady, C. I., Stolic, A., Radiation risk to children from computed tomography (2007) Pediatrics, 120 (3), pp. 677-682. , http: //pediatrics. aappublications. org/cgi/reprint/120/3/677, DOI 10. 1542/peds. 2007-1910
Brenner, D. J., Hall, E. J., Computed tomography - An increasing source of radiation exposure (2007) New England Journal of Medicine, 357 (22), pp. 2277-2284. , http: //content. nejm. org/cgi/reprint/357/22/2277. pdf, DOI 10. 1056/NEJMra072149
Hollis, D. P., Economou, J. S., Parks, L. C., Eggleston, J. C., Saryan, L. A., Czeister, J. L., Nuclear magnetic resonance studies of several experimental and human malignant tumors (1973) Cancer Res, 33, pp. 2156-2160
O'Donovan, P. B., Ross, J. S., Magnetic resonance of the pulmonary parenchyma: Initial experience at 0. 6 Tesla (1986) CardioVascular and Interventional Radiology, 8 (5-6), pp. 300-305
Cohen, M. D., Eigen, H., Scott, P. H., Tepper, R., Cory, D. A., Smith, J. A., Scales, R. L., Magnetic resonance imaging of inflammatory lung disorders: Preliminary studies in children (1986) Pediatr Pulmonol, 2, pp. 211-217
Fiel, S. B., Friedman, A. C., Caroline, D. F., Magnetic resonance imaging in young adults with cystic fibrosis (1987) Chest, 91 (2), pp. 181-184
McFadden, R. G., Carr, T. J., Wood, T. E., Proton magnetic resonance imaging to stage activity of interstitial lung disease (1987) Chest, 92 (1), pp. 31-39
Mohiaddin, R. H., Notohamiprodjio, G., Schoser, K., Magnetic resonance imaging of lung signal intensity and dimensions in patients with advanced lung disease before and after single lung transplantation (1995) Eur J Radiol, 20, pp. 16-22
Kennedy, M. P., Noone, P. G., Leigh, M. W., Zariwala, M. A., Minnix, S. L., Knowles, M. R., Molina, P. L., High-resolution CT of patients with primary ciliary dyskinesia (2007) American Journal of Roentgenology, 188 (5), pp. 1232-1238. , DOI 10. 2214/AJR. 06. 0965
Helbich, T. H., Heinz-Peer, G., Eichler, I., Wunderbaldinger, P., Gotz, M., Wojnarowski, C., Brasch, R. C., Herold, C. J., Cystic fibrosis: CT assessment of lung involvement in children and adults (1999) Radiology, 213 (2), pp. 537-544
M ller, N. L., Computed tomography and magnetic resonance imaging: Past, present and future (2002) Eur Respir J, 19 (SUPPL. 35), pp. 3-12
De Jong, P. A., Mayo, J. R., Golmohammadi, K., Nakano, Y., Lequin, M. H., Tiddens, H. A. W. M., Aldrich, J., Sin, D. D., Estimation of cancer mortality associated with repetitive computed tomography scanning (2006) American Journal of Respiratory and Critical Care Medicine, 173 (2), pp. 199-203. , http: //ajrccm. atsjournals. org/cgi/reprint/173/2/199, DOI 10. 1164/rccm. 200505-810OC
Linet, M. S., Kim, K. P., Rajaraman, P., Children's exposure to diagnostic medical radiation and cancer risk: Epidemiologic and dosimetric considerations (2009) Pediatr Radiol, 39 (SUPPL. 1), pp. 4-26
(2005) Biological Effects of Ionizing Radiation (BEIR) VII: Health Risks from Exposure to Low Levels of Ionizing Radiation, , Committee on the Biological Effects of Ionizing Radiation. Washington DC
Altes, T. A., Eichinger, M., Puderbach, M., Magnetic resonance imaging of the lung in cystic fibrosis (2007) Proceedings of the American Thoracic Society, 4 (4), pp. 321-327. , http: //pats. atsjournals. org/cgi/reprint/4/4/321, DOI 10. 1513/pats. 200611-181HT
Yi, C. A., Shin, K. M., Lee, K. S., Kim, B. T., Kim, H., Kwon, O. J., Choi, J. Y., Chung, M. J., Non-small cell lung cancer staging: Efficacy comparison of integrated PET/CT versus 3. 0-T whole-body MR imaging (2008) Radiology, 248, pp. 632-642
Heidemann, R. M., Griswold, M. A., Kiefer, B., Nittka, M., Wang, J., Jellus, V., Jakob, P. M., Resolution enhancement in lung1H imaging using parallel imaging methods (2003) Magnetic Resonance in Medicine, 49 (2), pp. 391-394. , DOI 10. 1002/mrm. 10349
Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings
BACKGROUND: Primary ciliary dyskinesia (PCD) is associated with pulmonary involvement that requires periodical assessment. Chest high-resolution computed tomography (HRCT) has become the method of choice to evaluate chronic lung disease, but entails exposure to ionizing radiation. Magnetic resonance imaging (MRI) has been proposed as a potential radiation-free technique in several chest disorders. Aim of our study is to evaluate whether high-field MRI is as effective as HRCT in identifying PCD pulmonary abnormalities. We also analyzed the relationships between the severity and extension of lung disease, and functional data.; METHODS: Thirteen PCD patients (8 children/5 adults; median age, 15.2 yrs) underwent chest HRCT and high-field 3T MRI, spirometry, and deep throat or sputum culture. Images were scored using a modified version of the Helbich system.; RESULTS: HRCT and MRI total scores were 12 (range, 6-20) and 12 (range, 5-17), respectively. Agreement between HRCT and MRI scores was good or excellent (r > 0.8). HRCT and MRI total scores were significantly related to forced vital capacity (r = -0.5, p = 0.05; and r = -0.7, p = 0.009, respectively) and forced expiratory volume at 1 second (r = -0.6, p = 0.03; and r = -0.7, p = 0.009, respectively).; CONCLUSION: Chest high-field 3T MRI appears to be as effective as HRCT in assessing the extent and severity of lung abnormalities in PCD. MRI scores might be used for longitudinal assessment and be an outcome surrogate in future studies.
Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings
No results.
Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings
Schutz K, Alecsandru D, Grimbacher B, Haddock J, Bruining A, Driessen G, De Vries E, Van Hagen PM, Hartmann I, Fraioli F, Milito C, Mitrevski M, Quinti I, Serra G, Kelleher P, Loebinger M, Litzman J, Postranecka V, Thon V, Babar J, Condliffe AM, Exley A, Kumararatne D, Screaton N, Jones A, Bondioni MP, Lougaris V, Plebani A, Soresina A, Sirignano C, Spadaro G, Galal N, Gonzalez-granado LI, Dettmer S, Stirling R, Chapel H, Lucas M, Patel S, Farber CM, Meyts I, Banerjee AK, Hackett S, Hurst JR, Warnatz K, Gathmann B, Weidemann J, Berthold D, Baumann U, Schutz K, Alecsandru D, Grimbacher B, Haddock J, Bruining A, Driessen G, De Vries E, Van Hagen PM, Hartmann I, Fraioli F, Milito C, Mitrevski M, Quinti I, Serra G, Kelleher P, Loebinger M, Litzman J, Postranecka V, Thon V, Babar J, Condliffe AM, Exley A, Kumararatne D, Screaton N, Jones A, Bondioni MP, Lougaris V, Plebani A, Soresina A, Sirignano C, Spadaro G, Galal N, Gonzalez-granado LI, Dettmer S, Stirling R, Chapel H, Lucas M, Patel S, Farber CM, Meyts I, B * Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group(148 views)(PDF 6 views) J Clin Immunol (ISSN: 0271-9142linking, 1573-2592), 2019 Jan; 3939(2): 45-54. Impact Factor:2.654 ViewExport to BibTeXExport to EndNote
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(307 views) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 ViewExport to BibTeXExport to EndNote