Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage(606 views) Merolla F, Pentimalli F, Pacelli R, Vecchio G, Fusco A, Grieco M, Celetti A
Keywords: Atm, Dna Damage, H4(d10s170), Ret Ptc1, Thyroid, Alanine, Atm Protein, Etoposide, Histone H3, Threonine, Apoptosis, Article, Carcinogenesis, Cell Survival, Clonogenic Assay, Controlled Study, Cytoplasm, Dna Synthesis, Enzyme Inhibition, Gene Silencing, Genotoxicity, Human, Human Cell, Ionizing Radiation, Lymphoblast, Mitosis, Priority Journal, Protein Function, Protein Localization, Protein Phosphorylation, Signal Transduction, Thyroid Tumor, Amino Acid Sequence, Cell Cycle Proteins, Cell Line, Cytoskeletal Proteins, Dna-Binding Proteins, Hela Cells, Molecular Sequence Data, Protein-Serine-Threonine Kinases, Thyroid Neoplasms, Tumor Suppressor Proteins, Mammalia, H4 (d10s170), Airway Obstruction, Brain Damage, Chronic Obstructive Lung Disease, Cognition, Cognitive Defect, Disease Severity, Drawing, Exercise, Hypoxemia, Letter, Major Clinical Study, Prognosis, Risk Assessment, Task Performance,
Affiliations: *** IBB - CNR ***
Dipartimento di Biologia e Patologia Cellulare e Molecolare, University 'Federico II', Naples, Italy
CNR Istituto di Biostrutture e Bioimmagini, Naples, Italy
Dipartimento di Medicina Sperimentale e Clinica, Università 'Magna Graecia', Catanzaro, Italy
Istituto di Endocrinologia Ed Oncologia Sperimentale del CNR, Naples, Italy
University Campus Bio-Medico, Rome, Italy
Italian National Research Center on Aging, Cosenza, Italy
Federico II University School of Medicine, Naples, Italy
Viale della Resistenza Pal. Alfa Scala H, I-87036 Rende (CS), Italy
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Bakkenist, C. J., Kastan, M. B., DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation (2003) Nature, 421, pp. 499-50
Canman, C. E., Lim, D. S., The role of ATM in DNA damage responses and cancer (1998) Oncogene, 17, pp. 3301-3308
Caudill, C. M., Zhu, Z., Ciampi, R., Stringer, J. R., Nikiforov, Y. E., Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: A model of carcinogenic chromosomal rearrangement induced by ionizing radiation (2005) J Clin Endocrinol Metab, 90, pp. 2364-2369
DiTullio Jr, R. A., Mochan, T. A., Venere, M., Bartkova, J., Sehested, M., Bartek, J., 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human (2002) Nat Cell Biol cancer, 4, pp. 998-1002
Goodhead, D. T., Initial events in the cellular effects of ionizing radiations: Clustered damage in DNA (1994) Int J Radiat Biol, 65, pp. 7-17
Jhiang, S. M., The RET proto-oncogene in human cancers (2000) Oncogene, 19, pp. 5590-5597
Jossart, G. H., O'Brien, B., Cheng, J. F., Tong, Q., Jhiang, S. M., Duh, Q., A novel multicolor hybridization scheme applied to localization of a transcribed sequence (D10S170/H4) and deletion mapping in the thyroid cancer cell line TPC-1 (1996) Cytogenet Cell Gene, 75, pp. 254-257
Kim, S. T., Lim, D. S., Canman, C. E., Kastan, M. B., Substrate specificities and identification of putative substrates of ATM kinase family members (1999) J Biol Chem, 274, pp. 37538-37543
Laemli, U. K., Cleavage of structural proteins during the assembly of the head of bacteriophage T4 (1970) Nature, 227, pp. 680-685
Lee, J. H., Paull, T. T., Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex (2004) Science, 304, pp. 93-96
Leskov, K. S., Criswell, T., Antonio, S., Li, J., Yang, C. R., Kinsella, T. J., When X-ray-inducible proteins meet DNA double strand break repair (2001) Semin Radiat Oncol, 11, pp. 352-372
Lim, D. S., Kim, S. T., Xu, B., Maser, R. S., Lin, J., Petrini, J. H., ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway (2000) Nature, 404, pp. 613-617
Little, J. B., Genomic instability and bystander effects: A historical perspective (2003) Oncogene, 22, pp. 6978-6987
Nikiforova, M. N., Ciampi, R., Salvatore, G., Santoro, M., Gandhi, M., Knauf, J. A., Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas (2004) Cancer Lett, 209, pp. 1-6
Obenauer, J. C., Cantley, L. C., Yaffe, M. B., Scansite 2. 0: Proteome-wide prediction of cell signaling interactions using short sequence motifs (2003) Nucleic Acids Res, 31, pp. 3635-3641
Penserga, E. T., Skorski, T., Fusion tyrosine kinases: A result and cause of genomic instability (2007) Oncogene, 26, pp. 11-20
Pierotti, M. A., Santoro, M., Jenkins, R. B., Sozzi, G., Bongarzone, I., Grieco, M., Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC (1992) Proc Natl Acad Sci USA, 89, pp. 1616-1620
Ron, E., Lubin, J. H., Shore, R. E., Mabuchi, K., Modan, B., Pottern, L. M., On target cell numbers in radiation-induced H4-RET mediated papillary thyroid cancer (1995) Radiat Res, 141, pp. 259-277
Sheils, O. M., O'Leary, J. J., Sweeney, E. C., Assessment of ret/PTC-1 rearrangements in neoplastic thyroid tissue using TaqMan RT-PCR (2000) J Pathol, 192, pp. 32-36
Smith, L. E., Nagar, S., Kim, G. J., Morgan, W. F., Radiation-induced genomic instability: Radiation quality and dose response (2003) Health Phys, 85, pp. 23-29
Ward, J. F., Radiation mutagenesis: The initial DNA lesions responsible (1995) Radiat Res, 142, pp. 362-368
Involvement of H4(D10S170) protein in ATM-dependent response to DNA damage