Antimicrobial peptides from plants: Stabilization of the γ core of a tomato defensin by intramolecular disulfide bond(605 views) Avitabile C, Capparelli R, Rigano MM, Fulgione A, Barone A, Pedone C, Romanelli A
University of Naples 'Federico II', School of Biotechnological Sciences, Department of Biological Sciences, Via Mezzocannone 16, Naples, 80134, Italy
References: Ganz, T., Defensins: antimicrobial peptides of innate immunity (2003) Nat. Rev. Immunol., 3, pp. 710-72
Zanetti, M., Gennaro, R., Romeo, D., Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain (1995) FEBS Lett., 374, pp. 1-5
Schittek, B., Hipfel, R., Sauer, B., Bauer, J., Kalbacher, H., Stevanovic, S., Schirle, M., Garbe, C., Dermcidin: a novel human antibiotic peptide secreted by sweat glands (2001) Nat. Immunol., 2, pp. 1133-1137
Castro, M.S., Fontes, W., Plant defense and antimicrobial peptides (2005) Protein Pept. Lett., 12, pp. 13-18
Stec, B., Plant thionins--the structural perspective (2006) Cell. Mol. Life Sci., 63, pp. 1370-1385
Chiche, L., Heitz, A., Gelly, J.C., Gracy, J., Chau, P.T., Ha, P.T., Hernandez, J.F., Le-Nguyen, D., Squash inhibitors: from structural motifs to macrocyclic knottins (2004) Curr. Protein Pept. Sci., 5, pp. 341-349
Yeaman, M.R., Yount, N.Y., Unifying themes in host defence effector polypeptides (2007) Nat. Rev. Microbiol., 5, pp. 727-740
Yount, N.Y., Andres, M.T., Fierro, J.F., Yeaman, M.R., The gamma-core motif correlates with antimicrobial activity in cysteine-containing kaliocin-1 originating from transferrins (2007) Biochim. Biophys. Acta, 1768, pp. 2862-2872
Yount, N.Y., Yeaman, M.R., Multidimensional signatures in antimicrobial peptides (2004) Proc. Natl. Acad. Sci. U.S.A., 101, pp. 7363-7368
Pelegrini, P.B., Franco, O.L., Plant gamma-thionins: novel insights on the mechanism of action of a multi-functional class of defense proteins (2005) Int. J. Biochem. Cell Biol., 37, pp. 2239-2253
Steinberg, D.A., Hurst, M.A., Fujii, C.A., Kung, A.H., Ho, J.F., Cheng, F.C., Loury, D.J., Fiddes, J.C., Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity (1997) Antimicrob. Agents Chemother., 41, pp. 1738-1742
Tran, D., Tran, P.A., Tang, Y.Q., Yuan, J., Cole, T., Selsted, M.E., Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides (2002) J. Biol. Chem., 277, pp. 3079-3084
The tomato genome sequence provides insights into fleshy fruit evolution (2012) Nature, 485, pp. 635-641
Rigano, M.M., Romanelli, A., Fulgione, A., Nocerino, N., D'Agostino, N., Avitabile, C., Frusciante, L., Capparelli, R., A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori (2012) J. Pept. Sci., 12, pp. 755-762
Romanelli, A., Moggio, L., Montella, R.C., Campiglia, P., Iannaccone, M., Capuano, F., Pedone, C., Capparelli, R., Peptides from Royal Jelly: studies on the antimicrobial activity of jelleins, jelleins analogs and synergy with temporins (2011) J. Pept. Sci., 17, pp. 348-352
Becker, K., Roth, R., Peters, G., Rapid and specific detection of toxigenic Staphylococcus aureus: use of two multiplex PCR enzyme immunoassays for amplification and hybridization of staphylococcal enterotoxin genes, exfoliative toxin genes, and toxic shock syndrome toxin 1 gene (1998) J. Clin. Microbiol., 36, pp. 2548-2553
Hong, Y., Liu, T., Lee, M.D., Hofacre, C.L., Maier, M., White, D.G., Ayers, S., Maurer, J.J., Rapid screening of Salmonella enterica serovars Enteritidis, Hadar, Heidelberg and Typhimurium using a serologically-correlative allelotyping PCR targeting the O and H antigen alleles (2008) BMC Microbiol., 8, p. 178
Tomasini, M.L., Zanussi, S., Sozzi, M., Tedeschi, R., Basaglia, G., De Paoli, P., Heterogeneity of cag genotypes in Helicobacter pylori isolates from human biopsy specimens (2003) J. Clin. Microbiol., 41, pp. 976-980
Bubert, A., Hein, I., Rauch, M., Lehner, A., Yoon, B., Goebel, W., Wagner, M., Detection and differentiation of Listeria spp. by a single reaction based on multiplex PCR (1999) Appl. Environ. Microbiol., 65, pp. 4688-4692
Martineau, F., Picard, F.J., Roy, P.H., Ouellette, M., Bergeron, M.G., Species-specific and ubiquitous DNA-based assays for rapid identification of Staphylococcus epidermidis (1996) J. Clin. Microbiol., 34, pp. 2888-2893
Capparelli, R., Romanelli, A., Iannaccone, M., Nocerino, N., Ripa, R., Pensato, S., Pedone, C., Iannelli, D., Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo (2009) PLoS One, 4, pp. e7191
Vinhal Costa Orsine, J., Vinhal da Costa, R., Carvalho da Silva, R., de Fatima Menezes Almeida Santos, M., Carvalho Garbi Novaes, M.R., The acute cytotoxicity and lethal concentration (LC50) of Agaricus sylvaticus through hemolytic activity on human erythrocyte (2012) Intl. J. Nutr. Metabol., 4, pp. 19-23
Fahrner, R.L., Dieckmann, T., Harwig, S.S., Lehrer, R.I., Eisenberg, D., Feigon, J., Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes (1996) Chem. Biol., 3, pp. 543-550
Mani, R., Cady, S.D., Tang, M., Waring, A.J., Lehrer, R.I., Hong, M., Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR (2006) Proc. Natl. Acad. Sci. U.S.A., 103, pp. 16242-16247
Kyte, J., Doolittle, R.F., A simple method for displaying the hydropathic character of a protein (1982) J. Mol. Biol., 157, pp. 105-132
Harwig, S.S., Waring, A., Yang, H.J., Cho, Y., Tan, L., Lehrer, R.I., Intramolecular disulfide bonds enhance the antimicrobial and lytic activities of protegrins at physiological sodium chloride concentrations (1996) Eur. J. Biochem., 240, pp. 352-357
Goldman, M.J., Anderson, G.M., Stolzenberg, E.D., Kari, U.P., Zasloff, M., Wilson, J.M., Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis (1997) Cell, 88, pp. 553-560
Mosca, D.A., Hurst, M.A., So, W., Viajar, B.S., Fujii, C.A., Falla, T.J., IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis (2000) Antimicrob. Agents Chemother., 44, pp. 1803-1808
Srinivas, N., Jetter, P., Ueberbacher, B.J., Werneburg, M., Zerbe, K., Steinmann, J., Van der Meijden, B., Robinson, J.A., Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa (2010) Science, 327, pp. 1010-1013
Lai, J.R., Huck, B.R., Weisblum, B., Gellman, S.H., Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues (2002) Biochemistry, 41, pp. 12835-12842
Sagaram, U.S., Pandurangi, R., Kaur, J., Smith, T.J., Shah, D.M., Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum (2011) PLoS One, 6, pp. e18550
Janssen, B.J., Schirra, H.J., Lay, F.T., Anderson, M.A., Craik, D.J., Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds (2003) Biochemistry, 42, pp. 8214-8222
Fant, F., Vranken, W., Broekaert, W., Borremans, F., Determination of the three-dimensional solution structure of Raphanus sativus antifungal protein 1 by 1H NMR (1998) J. Mol. Biol., 279, pp. 257-270
Bhunia, A., Mohanram, H., Domadia, P.N., Torres, J., Bhattacharjya, S., Designed beta-boomerang antiendotoxic and antimicrobial peptides: structures and activities in lipopolysaccharide (2009) J. Biol. Chem., 284, pp. 21991-22004
Castro, M. S., Fontes, W., Plant defense and antimicrobial peptides (2005) Protein Pept. Lett., 12, pp. 13-18
Yeaman, M. R., Yount, N. Y., Unifying themes in host defence effector polypeptides (2007) Nat. Rev. Microbiol., 5, pp. 727-740
Yount, N. Y., Andres, M. T., Fierro, J. F., Yeaman, M. R., The gamma-core motif correlates with antimicrobial activity in cysteine-containing kaliocin-1 originating from transferrins (2007) Biochim. Biophys. Acta, 1768, pp. 2862-2872
Yount, N. Y., Yeaman, M. R., Multidimensional signatures in antimicrobial peptides (2004) Proc. Natl. Acad. Sci. U. S. A., 101, pp. 7363-7368
Pelegrini, P. B., Franco, O. L., Plant gamma-thionins: novel insights on the mechanism of action of a multi-functional class of defense proteins (2005) Int. J. Biochem. Cell Biol., 37, pp. 2239-2253
Steinberg, D. A., Hurst, M. A., Fujii, C. A., Kung, A. H., Ho, J. F., Cheng, F. C., Loury, D. J., Fiddes, J. C., Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity (1997) Antimicrob. Agents Chemother., 41, pp. 1738-1742
Tran, D., Tran, P. A., Tang, Y. Q., Yuan, J., Cole, T., Selsted, M. E., Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides (2002) J. Biol. Chem., 277, pp. 3079-3084
Rigano, M. M., Romanelli, A., Fulgione, A., Nocerino, N., D'Agostino, N., Avitabile, C., Frusciante, L., Capparelli, R., A novel synthetic peptide from a tomato defensin exhibits antibacterial activities against Helicobacter pylori (2012) J. Pept. Sci., 12, pp. 755-762
Tomasini, M. L., Zanussi, S., Sozzi, M., Tedeschi, R., Basaglia, G., De Paoli, P., Heterogeneity of cag genotypes in Helicobacter pylori isolates from human biopsy specimens (2003) J. Clin. Microbiol., 41, pp. 976-980
Fahrner, R. L., Dieckmann, T., Harwig, S. S., Lehrer, R. I., Eisenberg, D., Feigon, J., Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes (1996) Chem. Biol., 3, pp. 543-550
Mani, R., Cady, S. D., Tang, M., Waring, A. J., Lehrer, R. I., Hong, M., Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR (2006) Proc. Natl. Acad. Sci. U. S. A., 103, pp. 16242-16247
Harwig, S. S., Waring, A., Yang, H. J., Cho, Y., Tan, L., Lehrer, R. I., Intramolecular disulfide bonds enhance the antimicrobial and lytic activities of protegrins at physiological sodium chloride concentrations (1996) Eur. J. Biochem., 240, pp. 352-357
Goldman, M. J., Anderson, G. M., Stolzenberg, E. D., Kari, U. P., Zasloff, M., Wilson, J. M., Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis (1997) Cell, 88, pp. 553-560
Mosca, D. A., Hurst, M. A., So, W., Viajar, B. S., Fujii, C. A., Falla, T. J., IB-367, a protegrin peptide with in vitro and in vivo activities against the microflora associated with oral mucositis (2000) Antimicrob. Agents Chemother., 44, pp. 1803-1808
Lai, J. R., Huck, B. R., Weisblum, B., Gellman, S. H., Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues (2002) Biochemistry, 41, pp. 12835-12842
Sagaram, U. S., Pandurangi, R., Kaur, J., Smith, T. J., Shah, D. M., Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum (2011) PLoS One, 6, pp. e18550
Janssen, B. J., Schirra, H. J., Lay, F. T., Anderson, M. A., Craik, D. J., Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds (2003) Biochemistry, 42, pp. 8214-8222
Antimicrobial peptides from plants: Stabilization of the γ core of a tomato defensin by intramolecular disulfide bond
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(295 views) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 ViewExport to BibTeXExport to EndNote