Receptor fragment approach to the binding between CCK8 peptide and cholecystokinin receptors: A fluorescence study on type B receptor fragment CCKB-R (352-379) (361 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005 Mar; 77(4): 205-211.
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Paper type: Journal Article,
Impact factor: 2.545, 5-year impact factor: 2.675
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-15944406860&partnerID=40&md5=68295c3e637425c1730fdc20e6149bbf
Keywords: Cholecystokinin Type B Receptor, Fluorescence Spectroscopy, Peptide-Receptor Binding, Surfactant Titration, Cck8 Peptides, Fluorescence Titrations, Receptor Fragment Approach, Binding Energy, Biological Membranes, Dissociation, Proteins, Spectroscopic Analysis, Polypeptides, Cholecystokinin A Receptor, Cholecystokinin B Receptor, Cholecystokinin Octapeptide, Cholecystokinin Receptor, Ligand, Solvent, Analytic Method, Article, Dissociation Constant, Drug Receptor Binding, Equilibrium Constant, Molecular Model, Reliability, Circular Dichroism, Peptide Fragments, Spectrometry,
Affiliations:
*** IBB - CNR ***
CIRPEB, Dipartimento di Chimica Biologica, Università Federico II, Via Mezzocannone 6/8, Naples, I-80134, Italy
INBIOS srl, Via Olivetti 1, Pozzuoli (NA), I-80078, Italy
Dipto. di Biochimica e Biofisica, CRISCEB, Seconda Universita di Napoli, Via Costantinopoli 16, I-80138 Naples, Italy
References:
Berthold, M., Bartfai, T., (1997) Neurochem Res, 22, pp. 1023-103
Aloj, L., Morelli, G., (2004) Curr Pharm Design, 10, pp. 3009-3031
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le Trong, I., Miyano, M., (2000) Science, 289, pp. 739-745
Mierke, D.F., Giragossian, C., (2001) Med Res Rev, 21, pp. 450-471
Pellegrini, M., Mierke, D.F., (1999) Biopolymers, 51, pp. 208-220
Piserchio, A., Prado, G.N., Zhang, R., Yu, J., Taylor, L., Polgar, P., Mierke, D.F., (2002) Biopolymers, 63, pp. 239-246
Macdonald, D., Mierke, D.F., Li, H., Pellegrini, M., Sachais, B., Krause, J.E., Leeman, S.E., Boyd, N.D., (2001) Biochemistry, 40, pp. 2530-2539
Giragossian, C., Mierke, D.F., (2001) Biochemistry, 40, pp. 3804-3809
Varnavas, A., Lassiani, L., Valenta, V., Berti, F., Mennuni, L., Makovec, F., (2003) Bioorg Med Chem, 11, pp. 741-751
Giragossian, C., Schaschke, N., Moroder, L., Mierke, D.F., (2004) Biochemistry, 43, pp. 2724-2731
Aloj, L., Caracò, C., Panico, M., Zannetti, A., Del Vecchio, S., Tesauro, D., De Luca, S., Salvatore, M., (2004) J Nucl Med, 45, pp. 485-494
Reubi, J.C., Waser, B., Schaer, J.C., (1998) Eur J Nucl Med, 25, pp. 481-490
Permyakov, E.A., (1993) Luminescent Spectroscopy of Proteins, , CRC Press: Boca Raton, FL
Ragone, R., De Luca, S., Tesauro, D., Pedone, C., Morelli, G., (2001) Biopolymers, 56, pp. 47-53
De Luca, S., Ragone, R., Bracco, C., Digilio, G., Aloj, L., Tesauro, D., Saviano, M., Morelli, G., (2003) ChemBioChem, 4, pp. 1176-1187
Edelhoch, H., (1967) Biochemistry, 6, pp. 1948-1954
Pace, C.N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci, 4, pp. 2411-2423
Gill, S.C., Von Hippel, P.H., (1989) Anal Biochem, 182, pp. 319-326
Ragone, R., Colonna, G., Servillo, L., Irace, G., (1985) Photochem Photobiol, 42, pp. 505-508
Emerson, M.F., Holtzer, A., (1965) J Phys Chem, 69, pp. 3718-3721
Esposito, C., Colicchio, P., Facchiano, A., Ragone, R., (1998) J Colloid Interface Sci, 200, pp. 310-312
Lauterwein, J., Bösch, C., Brown, L.R., Wüthrich, K., (1979) Biochim Biophys Acta, 556, pp. 244-264
Brown, L.R., Bösch, C., Wüthrich, K., (1981) Biochim Biophys Acta, 642, pp. 296-312
Le Maire, M., Champeil, P., Møller, J.V., (2000) Biochim Biophys Acta, 1508, pp. 86-111
Robinson, N.C., Tanford, C., (1975) Biochemistry, 14, pp. 369-378
Grefrath, S.P., Reynolds, J.A., (1974) Proc Natl Acad Sci U S A, 71, pp. 3913-3916
Reynolds, J.A., Stoeckenius, W., (1977) Proc Natl Acad Sci U S A, 74, pp. 2803-2804
Bohm, G., Muhr, R., Jaenicke, R., (1992) Protein Eng, 5, pp. 191-195
Manning, M.C., Woody, R.W., (1991) Biopolymers, 31, pp. 569-586
Kelly, S.M., Price, N.C., (2000) Curr Protein Peptide Sci, 1, pp. 349-384
Mierke, D. F., Giragossian, C., (2001) Med Res Rev, 21, pp. 450-471
Aloj, L., Carac, C., Panico, M., Zannetti, A., Del Vecchio, S., Tesauro, D., De Luca, S., Salvatore, M., (2004) J Nucl Med, 45, pp. 485-494
Reubi, J. C., Waser, B., Schaer, J. C., (1998) Eur J Nucl Med, 25, pp. 481-490
Permyakov, E. A., (1993) Luminescent Spectroscopy of Proteins, , CRC Press: Boca Raton, FL
Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci, 4, pp. 2411-2423
Gill, S. C., Von Hippel, P. H., (1989) Anal Biochem, 182, pp. 319-326
Emerson, M. F., Holtzer, A., (1965) J Phys Chem, 69, pp. 3718-3721
Lauterwein, J., B sch, C., Brown, L. R., W thrich, K., (1979) Biochim Biophys Acta, 556, pp. 244-264
Brown, L. R., B sch, C., W thrich, K., (1981) Biochim Biophys Acta, 642, pp. 296-312
Robinson, N. C., Tanford, C., (1975) Biochemistry, 14, pp. 369-378
Grefrath, S. P., Reynolds, J. A., (1974) Proc Natl Acad Sci U S A, 71, pp. 3913-3916
Reynolds, J. A., Stoeckenius, W., (1977) Proc Natl Acad Sci U S A, 74, pp. 2803-2804
Manning, M. C., Woody, R. W., (1991) Biopolymers, 31, pp. 569-586
Kelly, S. M., Price, N. C., (2000) Curr Protein Peptide Sci, 1, pp. 349-384
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005 Mar; 77(4): 205-211.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.545, 5-year impact factor: 2.675
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-15944406860&partnerID=40&md5=68295c3e637425c1730fdc20e6149bbf
Keywords: Cholecystokinin Type B Receptor, Fluorescence Spectroscopy, Peptide-Receptor Binding, Surfactant Titration, Cck8 Peptides, Fluorescence Titrations, Receptor Fragment Approach, Binding Energy, Biological Membranes, Dissociation, Proteins, Spectroscopic Analysis, Polypeptides, Cholecystokinin A Receptor, Cholecystokinin B Receptor, Cholecystokinin Octapeptide, Cholecystokinin Receptor, Ligand, Solvent, Analytic Method, Article, Dissociation Constant, Drug Receptor Binding, Equilibrium Constant, Molecular Model, Reliability, Circular Dichroism, Peptide Fragments, Spectrometry,
Affiliations:
*** IBB - CNR ***
CIRPEB, Dipartimento di Chimica Biologica, Università Federico II, Via Mezzocannone 6/8, Naples, I-80134, Italy
INBIOS srl, Via Olivetti 1, Pozzuoli (NA), I-80078, Italy
Dipto. di Biochimica e Biofisica, CRISCEB, Seconda Universita di Napoli, Via Costantinopoli 16, I-80138 Naples, Italy
References:
Berthold, M., Bartfai, T., (1997) Neurochem Res, 22, pp. 1023-103
Aloj, L., Morelli, G., (2004) Curr Pharm Design, 10, pp. 3009-3031
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le Trong, I., Miyano, M., (2000) Science, 289, pp. 739-745
Mierke, D.F., Giragossian, C., (2001) Med Res Rev, 21, pp. 450-471
Pellegrini, M., Mierke, D.F., (1999) Biopolymers, 51, pp. 208-220
Piserchio, A., Prado, G.N., Zhang, R., Yu, J., Taylor, L., Polgar, P., Mierke, D.F., (2002) Biopolymers, 63, pp. 239-246
Macdonald, D., Mierke, D.F., Li, H., Pellegrini, M., Sachais, B., Krause, J.E., Leeman, S.E., Boyd, N.D., (2001) Biochemistry, 40, pp. 2530-2539
Giragossian, C., Mierke, D.F., (2001) Biochemistry, 40, pp. 3804-3809
Varnavas, A., Lassiani, L., Valenta, V., Berti, F., Mennuni, L., Makovec, F., (2003) Bioorg Med Chem, 11, pp. 741-751
Giragossian, C., Schaschke, N., Moroder, L., Mierke, D.F., (2004) Biochemistry, 43, pp. 2724-2731
Aloj, L., Caracò, C., Panico, M., Zannetti, A., Del Vecchio, S., Tesauro, D., De Luca, S., Salvatore, M., (2004) J Nucl Med, 45, pp. 485-494
Reubi, J.C., Waser, B., Schaer, J.C., (1998) Eur J Nucl Med, 25, pp. 481-490
Permyakov, E.A., (1993) Luminescent Spectroscopy of Proteins, , CRC Press: Boca Raton, FL
Ragone, R., De Luca, S., Tesauro, D., Pedone, C., Morelli, G., (2001) Biopolymers, 56, pp. 47-53
De Luca, S., Ragone, R., Bracco, C., Digilio, G., Aloj, L., Tesauro, D., Saviano, M., Morelli, G., (2003) ChemBioChem, 4, pp. 1176-1187
Edelhoch, H., (1967) Biochemistry, 6, pp. 1948-1954
Pace, C.N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci, 4, pp. 2411-2423
Gill, S.C., Von Hippel, P.H., (1989) Anal Biochem, 182, pp. 319-326
Ragone, R., Colonna, G., Servillo, L., Irace, G., (1985) Photochem Photobiol, 42, pp. 505-508
Emerson, M.F., Holtzer, A., (1965) J Phys Chem, 69, pp. 3718-3721
Esposito, C., Colicchio, P., Facchiano, A., Ragone, R., (1998) J Colloid Interface Sci, 200, pp. 310-312
Lauterwein, J., Bösch, C., Brown, L.R., Wüthrich, K., (1979) Biochim Biophys Acta, 556, pp. 244-264
Brown, L.R., Bösch, C., Wüthrich, K., (1981) Biochim Biophys Acta, 642, pp. 296-312
Le Maire, M., Champeil, P., Møller, J.V., (2000) Biochim Biophys Acta, 1508, pp. 86-111
Robinson, N.C., Tanford, C., (1975) Biochemistry, 14, pp. 369-378
Grefrath, S.P., Reynolds, J.A., (1974) Proc Natl Acad Sci U S A, 71, pp. 3913-3916
Reynolds, J.A., Stoeckenius, W., (1977) Proc Natl Acad Sci U S A, 74, pp. 2803-2804
Bohm, G., Muhr, R., Jaenicke, R., (1992) Protein Eng, 5, pp. 191-195
Manning, M.C., Woody, R.W., (1991) Biopolymers, 31, pp. 569-586
Kelly, S.M., Price, N.C., (2000) Curr Protein Peptide Sci, 1, pp. 349-384
Mierke, D. F., Giragossian, C., (2001) Med Res Rev, 21, pp. 450-471
Aloj, L., Carac, C., Panico, M., Zannetti, A., Del Vecchio, S., Tesauro, D., De Luca, S., Salvatore, M., (2004) J Nucl Med, 45, pp. 485-494
Reubi, J. C., Waser, B., Schaer, J. C., (1998) Eur J Nucl Med, 25, pp. 481-490
Permyakov, E. A., (1993) Luminescent Spectroscopy of Proteins, , CRC Press: Boca Raton, FL
Pace, C. N., Vajdos, F., Fee, L., Grimsley, G., Gray, T., (1995) Protein Sci, 4, pp. 2411-2423
Gill, S. C., Von Hippel, P. H., (1989) Anal Biochem, 182, pp. 319-326
Emerson, M. F., Holtzer, A., (1965) J Phys Chem, 69, pp. 3718-3721
Lauterwein, J., B sch, C., Brown, L. R., W thrich, K., (1979) Biochim Biophys Acta, 556, pp. 244-264
Brown, L. R., B sch, C., W thrich, K., (1981) Biochim Biophys Acta, 642, pp. 296-312
Robinson, N. C., Tanford, C., (1975) Biochemistry, 14, pp. 369-378
Grefrath, S. P., Reynolds, J. A., (1974) Proc Natl Acad Sci U S A, 71, pp. 3913-3916
Reynolds, J. A., Stoeckenius, W., (1977) Proc Natl Acad Sci U S A, 74, pp. 2803-2804
Manning, M. C., Woody, R. W., (1991) Biopolymers, 31, pp. 569-586
Kelly, S. M., Price, N. C., (2000) Curr Protein Peptide Sci, 1, pp. 349-384
Receptor fragment approach to the binding between CCK8 peptide and cholecystokinin receptors: A fluorescence study on type B receptor fragment CCKB-R (352-379)
Fluorescence titrations in a membrane mimetic solvent system allowed us to estimate that the dissociation constant of the bimolecular complex between CCK8 peptide and cholecystokinin type B receptor fragment CCKB-R (352-379) is in the micromolar range. When considered in the context of the full receptor/ligand model, these experiments demonstrate that the receptor fragment chosen on the basis of previous structural studies represents a reliable model system to monitor the ability of CCK8 or CCK8 analogs to bind the cholecystokinin receptor. Together with previous studies, this confirms that the receptor fragment approach adopted to define the binding mode of the CCK8 fragment of cholecystokinin with its two receptors, CCKA and CCKB can be used to characterize the binding from the equilibrium standpoint. In this context, fluorescence spectros-copy proves to be the favored technique to measure dissociation constants in the nanomolar to micromolar range. (C) 2005 Wiley Periodicals, Inc.
Fluorescence titrations in a membrane mimetic solvent system allowed us to estimate that the dissociation constant of the bimolecular complex between CCK8 peptide and cholecystokinin type B receptor fragment CCKB-R (352-379) is in the micromolar range. When considered in the context of the full receptor/ligand model, these experiments demonstrate that the receptor fragment chosen on the basis of previous structural studies represents a reliable model system to monitor the ability of CCK8 or CCK8 analogs to bind the cholecystokinin receptor. Together with previous studies, this confirms that the receptor fragment approach adopted to define the binding mode of the CCK8 fragment of cholecystokinin with its two receptors, CCKA and CCKB can be used to characterize the binding from the equilibrium standpoint. In this context, fluorescence spectros-copy proves to be the favored technique to measure dissociation constants in the nanomolar to micromolar range. (C) 2005 Wiley Periodicals, Inc.
Receptor fragment approach to the binding between CCK8 peptide and cholecystokinin receptors: A fluorescence study on type B receptor fragment CCKB-R (352-379)
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Receptor fragment approach to the binding between CCK8 peptide and cholecystokinin receptors: A fluorescence study on type B receptor fragment CCKB-R (352-379)
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Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
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Accardo A, Tesauro D, Del Pozzo L, Mangiapia G, Paduano L, Morelli G
* Micelles by self-assembling peptide-conjugate amphiphile: Synthesis and structural characterization (403 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): 903-910.
Impact Factor: 1.654
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Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (608 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
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Chambery A, Pisante M, Di Maro A, Di Zazzo E, Ruvo M, Costantini S, Colonna G, Parente A
* Invariant Ser211 is involved in the catalysis of PD-L4, type I RIP from Phytolacca dioica leaves (364 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Apr 1; 67(1): 209-218.
Impact Factor: 3.354
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Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
* Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments (512 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.
Impact Factor: 3.354
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Puglisi A, Purrello R, Rizzarelli E, Sortino S, Vecchio G
* Spectroscopic and self-association behavior of a porphyrin-β- cyclodextrin conjugate (375 views)
New J Chem (ISSN: 1144-0546), 2007; 31(8): 1499-1506.
Impact Factor: 2.651
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De Luca S, Saviano M, Della Moglie R, Digilio G, Bracco C, Aloj L, Tarallo L, Pedone C, Morelli G
* Conformationally constrained CCK8 analogues obtained from a rationally designed peptide library as ligands for cholecystokinin type B receptor (421 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2006 Sep; 1(9): 997-1006.
Impact Factor: 3.046
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De Luca S, Saviano M, Lassiani L, Yannakopoulou K, Stefanidou P, Aloj L, Morelli G, Varnavas A
* Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their "receptor desmodynamic processes" (438 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Apr 20; 49(8): 2456-2462.
Impact Factor: 5.115
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Improta R, Barone V
* Absorption and fluorescence spectra of uracil in the gas phase and in aqueous solution: A TD-DFT quantum mechanical study (379 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Nov 10; 126(44): 14320-14321.
Impact Factor: 6.903
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De Luca S, Ragone R, Bracco C, Digilio G, Aloj L, Tesauro D, Saviano M, Pedone C, Morelli G
* A cyclic CCK8 analogue selective for the cholecystokinin type A receptor: design, synthesis, NMR structure and binding measurements (472 views)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2003 Nov 7; 4(11): 1176-1187.
Impact Factor: 3.992
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De Luca S, Ragone R, Bracco C, Digilio G, Tesauro D, Saviano M, Pedone C, Morelli G
* The role of segment 32-47 of cholecystokinin receptor type A in CCK8 binding: Synthesis, nuclear magnetic resonance, circular dichroism and fluorescence studies (349 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2003 Mar; 9(3): 156-169.
Impact Factor: 1.377
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Ragone R, De Luca S, Tesauro D, Pedone C, Morelli G
Fluorescence studies on the binding between 1-47 fragment of cholecystokinin receptor CCKA-R(1-47) and nonsulfated cholecystokinin octapeptide CCK8 (419 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 47-53.
Impact Factor: 2.405
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Gallo P, Saviano M, Rossi F, Pavone V, Pedone C, Ragone R, Stiuso P, Colonna G
SPECIFIC INTERACTION BETWEEN CYCLOPHILIN AND CYCLIC-PEPTIDES (484 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1995 Sep; 36(3): 273-281.
Impact Factor: 2.425
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* Thienoguanosine brightness in DNA duplexes is governed by the localization of itsππ* excitation in the lowest energy absorption band (16 views)
Methods Appl Fluoresc (ISSN: 2050-6120linking), 2022 May 5; 10(3): N/D-N/D.
Impact Factor: 2.79
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Marchesani F, Gianquinto E, Autiero I, Michielon A, Campanini B, Faggiano S, Bettati S, Mozzarelli A, Spyrakis F, Bruno S
* The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase (61 views)
Febs J (ISSN: 1742-464xlinking), 2021 May; 288(9): 3034-3054.
Impact Factor: 4.739
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Martinez-fernandez L, Gustavsson T, Diederichsen U, Improta R
* Excited State Dynamics of 8-Vinyldeoxyguanosine In Aqueous Solution Studied by Time-Resolved Fluorescence Spectroscopy and Quantum Mechanical Calculations (44 views)
Molecules (ISSN: 1420-3049linking, 1420-3049electronic), 2020 Feb 13; 25(4): N/D-N/D.
Impact Factor: 3.267
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Caporale A, Monti A, Selis F, Sandomenico A, Tonon G, Ruvo M, Doti N
* A comparative analysis of catalytic activity and stability of microbial transglutaminase in controlled denaturing conditions (164 views)
J Biotechnol (ISSN: 0168-1656linking), 2019 Aug 20; 302: 48-57.
Impact Factor: 3.163
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Martinez-fernandez L, Gavvala K, Sharma R, Didier P, Richert L, Segarra Marti J, Mori M, Mely Y, Improta R
* Excited-State Dynamics of Thienoguanosine, an Isomorphic Highly Fluorescent Analogue of Guanosine (177 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2019 May 28; 25(30): 7375-7386.
Impact Factor: 5.16
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Martinez-fernandez L, Pepino AJ, Segarra-marti J, Jovaisaite J, Vaya I, Nenov A, Markovitsi D, Gustavsson T, Banyasz A, Garavelli M, Improta R
* Photophysics of Deoxycytidine and 5-Methyldeoxycytidine in Solution: A Comprehensive Picture by Quantum Mechanical Calculations and Femtosecond Fluorescence Spectroscopy (242 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2017 Jun 14; 139(23): 7780-7791.
Impact Factor: 14.357
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Vayá I, Brazard J, Huix-rotllant M, Thazhathveetil AK, Lewis FD, Gustavsson T, Burghardt I, Improta R, Markovitsi D
* High-Energy Long-Lived Mixed Frenkel-Charge-Transfer Excitons: From Double Stranded (AT)n to Natural DNA (299 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016; 22(14): 4904-4914.
Impact Factor: 5.317
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Calce E, Monfregola L, Saviano M, De Luca S
* HER2-mediated anticancer drug delivery: strategies to prepare targeting ligands highly specific for the receptor (571 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 May 20; 22(21): 2525-2538.
Impact Factor: 3.455
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (409 views)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Cohen SS, Riven I, Cortajarena AL, De Rosa L, D'Andrea LD, Regan L, Haran G
* Probing the molecular origin of native-state flexibility in repeat proteins (353 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2015; 137(32): 10367-10373.
Impact Factor: 13.038
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Huix-Rotllant M, Brazard J, Improta R, Burghardt I, Markovitsi D
* Stabilization of mixed frenkel-charge transfer excitons extended across both strands of guanine-cytosine DNA duplexes (379 views)
J Phys Chem Lett (ISSN: 1948-7185, 1948-7185electronic, 1948-7185linking), 2015; 6(12): 2247-2251.
Impact Factor: 8.539
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Changenet-Barret P, Gustavsson T, Improta R, Markovitsi D
* Ultrafast Excited-State Deactivation of 8-Hydroxy-2′-deoxyguanosine Studied by Femtosecond Fluorescence Spectroscopy and Quantum-Chemical Calculations (441 views)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2015; 119(23): 6131-6139.
Impact Factor: 2.883
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Chi M-C, Lo Y-H, Chen Y-Y, Lin L-L, Merlino A
* γ-Glutamyl transpeptidase architecture: Effect of extra sequence deletion on autoprocessing, structure and stability of the protein from Bacillus licheniformis (313 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(12): 2290-2297.
Impact Factor: 4.882
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Cantisani M, Falanga A, Incoronato N, Russo L, De Simone A, Morelli G, Berisio R, Galdiero M, Galdiero S
* Conformational modifications of gB from herpes simplex virus type 1 analyzed by synthetic peptides (639 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8366-8376.
Impact Factor: 5.48
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Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M
* Peptide-Lipid Interactions: Experiments and Applications (1013 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 Sep; 14(9): 18758-18789.
Impact Factor: 2.339
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Satriano C, Sfrazzetto GT, Amato ME, Ballistreri FP, Copani A, Giuffrida ML, Grasso G, Pappalardo A, Rizzarelli E, Tomaselli GA, Toscano RM
* A ratiometric naphthalimide sensor for live cell imaging of copper(i) (455 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2013 Jun 21; 49(49): 5565-5567.
Impact Factor: 6.718
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Banyasz A, Gustavsson T, Onidas D, Changenet-Barret P, Markovitsi D, Improta R
* Multi-pathway excited state relaxation of adenine oligomers in aqueous solution: A joint theoretical and experimental study (304 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Mar; 19(11): 3762-3774.
Impact Factor: 5.696
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Travaglia A, Satriano C, Giuffrida ML, La Mendola D, Rampazzo E, Prodi L, Rizzarelli E
* Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide (338 views)
Soft Matter (ISSN: 1744-683x), 2013; 9(18): 4648-4654.
Impact Factor: 4.151
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Banyasz A, Douki T, Improta R, Gustavsson T, Onidas D, Vaya I, Perron M, Markovitsi D
* Electronic excited states responsible for dimer formation upon UV absorption directly by thymine strands: Joint experimental and theoretical study (360 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2012 Sep 12; 134(36): 14834-14845.
Impact Factor: 10.677
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Hua Y, Changenet-Barret P, Improta R, Vaya I, Gustavsson T, Kotlyar AB, Zikich D, Sket P, Plavec J, Markovitsi D
* Cation effect on the electronic excited states of guanine nanostructures studied by time-resolved fluorescence spectroscopy (394 views)
J Phys Chem C (ISSN: 1932-7447), 2012 Jul 12; 116(27): 14682-14689.
Impact Factor: 4.814
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Musumeci D, Oliviero G, Roviello GN, Bucci EM, Piccialli G
* G-quadruplex-forming oligonucleotide conjugated to magnetic nanoparticles: Synthesis, characterization, and enzymatic stability assays (754 views)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812, 1520-4812electronic), 2012 Mar 21; 23(3): 382-391.
Impact Factor: 4.58
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Merlino A, Vitiello G, Grimaldi M, Sica F, Busi E, Basosi R, D’Ursi A, Fragneto G, Paduano L, D’Errico G
* Destabilization of Lipid Membranes by a Peptide Derived from Glycoprotein gp36 of Feline Immunodeficiency Virus: A Combined Molecular Dynamics/Experimental Study (470 views)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2012 Jan 12; 116(1): 401-412.
Impact Factor: 3.607
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Tosco A, Monti MC, Fontanella B, Montefusco S, D'Andrea LD, Ziaco B, Baldantoni D, Rio MC, Marzullo L
* Copper binds the carboxy-terminus of trefoil protein 1 (TFF1), favoring its homodimerization and motogenic activity (850 views)
Cell Mol Life Sci (ISSN: 1420-9071electronic, 1420-682xlinking), 2010 Jun; 67(11): 1943-1955.
Impact Factor: 7.047
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Accardo A, Tesauro D, Morisco A, Mangiapia G, Vaccaro M, Gianolio E, Heenan RK, Paduano L, Morelli G
* Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex (398 views)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257linking), 2009 May; 14(4): 587-599.
Impact Factor: 3.415
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Morisco A, Accardo A, Gianolio E, Tesauro D, Benedetti E, Morelli G
* Micelles derivatized with octreotide as potential target-selective contrast agents in MRI (417 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 242-250.
Impact Factor: 1.807
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Vaccaro M, Mangiapia G, Accardo A, Tesauro D, Gianolio E, Frielinghaus H, Morelli G, Paduano L
* Polymerized mixed aggregates containing gadolinium complex and CCK8 peptide (423 views)
Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Del Pozzo L, Mangiapia G, Paduano L, Morelli G
* Micelles by self-assembling peptide-conjugate amphiphile: Synthesis and structural characterization (403 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): 903-910.
Impact Factor: 1.654
View Export to BibTeX Export to EndNote
Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (608 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
View Export to BibTeX Export to EndNote
Chambery A, Pisante M, Di Maro A, Di Zazzo E, Ruvo M, Costantini S, Colonna G, Parente A
* Invariant Ser211 is involved in the catalysis of PD-L4, type I RIP from Phytolacca dioica leaves (364 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Apr 1; 67(1): 209-218.
Impact Factor: 3.354
View Export to BibTeX Export to EndNote
Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
* Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments (512 views)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.
Impact Factor: 3.354
View Export to BibTeX Export to EndNote
Puglisi A, Purrello R, Rizzarelli E, Sortino S, Vecchio G
* Spectroscopic and self-association behavior of a porphyrin-β- cyclodextrin conjugate (375 views)
New J Chem (ISSN: 1144-0546), 2007; 31(8): 1499-1506.
Impact Factor: 2.651
View Export to BibTeX Export to EndNote
De Luca S, Saviano M, Della Moglie R, Digilio G, Bracco C, Aloj L, Tarallo L, Pedone C, Morelli G
* Conformationally constrained CCK8 analogues obtained from a rationally designed peptide library as ligands for cholecystokinin type B receptor (421 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2006 Sep; 1(9): 997-1006.
Impact Factor: 3.046
View Export to BibTeX Export to EndNote
De Luca S, Saviano M, Lassiani L, Yannakopoulou K, Stefanidou P, Aloj L, Morelli G, Varnavas A
* Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their "receptor desmodynamic processes" (438 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Apr 20; 49(8): 2456-2462.
Impact Factor: 5.115
View Export to BibTeX Export to EndNote
Improta R, Barone V
* Absorption and fluorescence spectra of uracil in the gas phase and in aqueous solution: A TD-DFT quantum mechanical study (379 views)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2004 Nov 10; 126(44): 14320-14321.
Impact Factor: 6.903
View Export to BibTeX Export to EndNote
De Luca S, Ragone R, Bracco C, Digilio G, Aloj L, Tesauro D, Saviano M, Pedone C, Morelli G
* A cyclic CCK8 analogue selective for the cholecystokinin type A receptor: design, synthesis, NMR structure and binding measurements (472 views)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2003 Nov 7; 4(11): 1176-1187.
Impact Factor: 3.992
View Export to BibTeX Export to EndNote
De Luca S, Ragone R, Bracco C, Digilio G, Tesauro D, Saviano M, Pedone C, Morelli G
* The role of segment 32-47 of cholecystokinin receptor type A in CCK8 binding: Synthesis, nuclear magnetic resonance, circular dichroism and fluorescence studies (349 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2003 Mar; 9(3): 156-169.
Impact Factor: 1.377
View Export to BibTeX Export to EndNote
Ragone R, De Luca S, Tesauro D, Pedone C, Morelli G
Fluorescence studies on the binding between 1-47 fragment of cholecystokinin receptor CCKA-R(1-47) and nonsulfated cholecystokinin octapeptide CCK8 (419 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 47-53.
Impact Factor: 2.405
View Export to BibTeX Export to EndNote
Gallo P, Saviano M, Rossi F, Pavone V, Pedone C, Ragone R, Stiuso P, Colonna G
SPECIFIC INTERACTION BETWEEN CYCLOPHILIN AND CYCLIC-PEPTIDES (484 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1995 Sep; 36(3): 273-281.
Impact Factor: 2.425
View Export to BibTeX Export to EndNote
38 Records (38 excluding Abstracts).
Total impact factor: 175.075 (175.075 excluding Abstracts).
Total 5 year impact factor: 171.046 (171.046 excluding Abstracts).
Total impact factor: 175.075 (175.075 excluding Abstracts).
Total 5 year impact factor: 171.046 (171.046 excluding Abstracts).
361 views. Last view on Thursday 30 March 2023, 17:11:01
ibb.cnr.it
