Conformational Behaviour Of C (alpha, Alpha)-Diphenylglycine: Folded Vs. Extended Structures In Dphig-Containing Tripeptides(454 views) Pavone V, Lombardi A, Saviano M, Nastri F, Zaccaro L, Maglio O, Pedone C, Omote Y, Yamanaka Y, Yamada T
Keywords: Cα, α-Disubstituted Amino Acids, Conformation, Crystal Structure, Molecular Dynamics, Drug Derivative, Glycine, Article, Chemistry, Protein Conformation, Protein Folding, X Ray Diffraction, X-Ray Diffraction,
Affiliations: Ctro. Interuniversitario Ric. sui P., CEINGE-Biotecnologie Avanzate C., Univ. di Napoli 'Federico II', 80134 Napoli, Italy
Department of Chemistry, Faculty of Science, Konan University, 658 Kobe, Japan
Dipartimento di Chimica, Università di Napoli, Via Mezzocannone 4, I-80134 Napoli, Italy
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Dentino, A. R., Raj, P. A., Bhandary, K. K., Wilson, M. E., Levine, M. J., Role of peptide backbone conformation on biological activity of chemotactic peptides (1991) J. Biol. Chem., 266, pp. 18460-18468
Karle, I. L., Rao, R. B., Prasad, S., Kaul, R., Balaram, P., Nonstandard amino acids in conformational design of peptides. Helical structures in crystals of 5-10 residue peptides containing dipropylglycine and dibutylglycine (1994) J. Am. Chem. Soc., 116, pp. 10356-10361
Poupaert, J. H., Vandervorst, D., Guiot, P., Moustafa, M. M. M., Dumont, P., Structure-activity relationships of phenytoin-like anticonvulsant drugs (1984) J. Med. Chem., 27, pp. 76-78
Wong, M. G., Delfina, J. A., Andrews, P. R., Conformational analysis of clinically active anticonvulsant drugs (1986) J. Med. Chem., 29, pp. 562-572
Frenk, B. A., (1985) Structure Determination Package, a System of Computer Programs, , College Station, Texas, and Enraf Nonius, Delft, The Netherlands
Momany, F. A., McGuire, R. F., Burgess, A. W., Scheraga, H. A., Energy parameters in polypeptides. VII. Geometric parameters, partial atomic charges, non bonded interactions, hydrogen bond interactions, and intrinsic torsional potentials for the naturally occurring amino acids (1975) J. Phys. Chem., 79, pp. 2361-2381
N methy, G., Pottle, M. S., Scheraga, H. A., Energy parameters in polypeptides. 9. Updating of geometrical parameters, non bonded interactions, and hydrogen bond interactions for the naturally occurring amino acids (1983) J. Phys. Chem., 87, pp. 1883-1887
Hagler, A. T., Lifson, S., Dauber, P. J., Consistent force field studies of intermolecular forces in hydrogen-bonded crystals. 2. A benchmark for the objective comparison of alternative force field (1979) J. Am. Chem. Soc., 101, pp. 5122-5130
Zimmerman, S. S., Pottle, M. S., Nemethy, G., Scheraga, H. A., Conformational analysis of the 20 naturally occurring amino acids residues using ECEPP (1977) Macromolecules, 10, pp. 1-9
Brooks III, C. L., Montgomery Pettitt, B., Karplus, M., (1988) Proteins: A Theoretical Perspective of Dynamics, Structure and Thermodynamics, , Wiley, New York
Conformational Behaviour Of C (alpha, Alpha)-Diphenylglycine: Folded Vs. Extended Structures In Dphig-Containing Tripeptides