Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis(407 views) Manna R, Salvatore M, Scuderi F, Papa G, Marietti G, Greco AV, Ghirlanda G, Gambassi G
Diabetes Res (ISSN: 0265-5985), 1988 Nov; 9(3): 101-103.
Keywords: C Peptide, Insulin, Pancreas Islet Cell Antibody, Adolescent, Adult, Clinical Article, Female, Human, Insulin Dependent Diabetes Mellitus, Priority Journal, Remission, School Child, Autoantibodies, C-Peptide, Insulin-Dependent, Follow-Up Studies, Hla Antigens, Islets Of Langerhans, Support, Non-U S Gov,
Affiliations: Department of Medicine, Catholic University of Sacred Heart, I-00168 Rome, Italy
References: Not available.
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis
We have studied 27 insulin-dependent diabetic patients since diagnosis for a period of six months; at diabetes onset and later on, ICA were found in 17 of them, whereas they were undetectable in 10 patients: age was remarkably homogeneous in the two groups. At diabetes onset, no significant differences were found in insulin requirement between ICA positive and ICA negative patients; however, six months after diagnosis, we observed that insulin requirement to keep metabolic control was significantly higher in ICA positive than in ICA negative subjects (0.515±0.2 U/Kg versus 0.22±0.15 U/Kg, p
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis
No results.
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis
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