Functional aspects of ribosomal architecture: Symmetry, chirality and regulation(730 views) Zarivach R, Bashan A, Berisio R, Harms J, Auerbach T, Schluenzen F, Bartels H, Baram D, Pyetan E, Sittner A, Amit M, Hansen HAS, Kessler M, Liebe C, Wolff A, Agmon I, Yonath A
Department of Structural Biology, Weizmann Institute, 76100 Rehovot, Israel
Max-Planck-Res. U. Ribosomal Struct., 22603 Hamburg, Germany
Inst. of Biostructure and Bioimaging, CNR, 80138 Napoli, Italy
References: Not available.
Functional aspects of ribosomal architecture: Symmetry, chirality and regulation
The functional aspects of ribosomal architecture were studied. The ribosome possesses three tRNA binding sites named according to their function. It was observed that the small ribosomal subunit facilitates the initiation of the translation process and is involved in choosing the frame to be translated. The high-resolution structures of both ribosomal subunits revealed that most stages of protein biosynthesis including decoding of genetic information are navigated and controlled by the elaborate ribosomal architectural design.
Functional aspects of ribosomal architecture: Symmetry, chirality and regulation
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Functional aspects of ribosomal architecture: Symmetry, chirality and regulation