Istituto di Biostrutture e Bioimmagini-CNR, via Mezzocannone 16, 80134 Naples, Italy
Dipartmento di Chimica Ugo Schiff, Università Degli Studi di Firenze, Via della Lastruccia, 3, 50019 Sesto Fiorentino (Firenze), Italy
Department of Geosciences, Princeton University, Princeton, NJ 08544, United States
References: Satoh, D., Hiraoka, Y., Colman, B., Matsuda, Y., Physiological and molecular biological characterization of intracellular carbonic anhydrase from the marine diatom Phaeodactylum tricornutum (2001) Plant Physiol., 126, pp. 1459-147
Supuran, C.T., Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators (2008) Nat. Rev. Drug Discov., 7, pp. 168-181
Supuran, C.T., Scozzafava, A., Casini, A., Carbonic anhydrase inhibitors (2003) Med. Res. Rev., 23, pp. 146-189
Domsic, J.F., Avvaru, B.S., Kim, C.U., Gruner, S.M., Agbandje-Mckenna, M., Silverman, D.N., McKenna, R., Entrapment of carbon dioxide in the active site of carbonic anhydrase II (2008) J. Biol. Chem., 283, pp. 30766-30771
Nishimori, I., Onishi, S., Takeuchi, H., Supuran, C.T., The α and β classes carbonic anhydrases from Helicobacter pylori as novel drug targets (2008) Curr. Pharm. Des., 14, pp. 622-630
Schlicker, C., Hall, R.A., Vullo, D., Middelhaufe, S., Gertz, M., Supuran, C.T., Mühlschlegel, F.A., Steegborn, C., Structure and inhibition of the CO 2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans (2009) J. Mol. Biol., 385, pp. 1207-1220
Isik, S., Kockar, F., Aydin, M., Arslan, O., Guler, O.O., Innocenti, A., Scozzafava, A., Supuran, C.T., Carbonic anhydrase inhibitors. Inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates (2009) Bioorg. Med. Chem., 17, pp. 1158-1163
Carta, F., Maresca, A., Covarrubias, A.S., Mowbray, S.L., Jones, T.A., Supuran, C.T., Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active β-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c (2009) Bioorg. Med. Chem. Lett., 19, pp. 6649-6654
Lane, T.W., Morel, F.M.M., A biological function for cadmium in marine diatoms (2000) Proc. Natl. Acad. Sci. USA, 97, pp. 4627-4631
Ferry, J.F., The gamma-carbonic anhydrases (2010) Biochim. Biophys. Acta, 1804, pp. 374-381
Rowlett, R.S., Structure and catalytic mechanism of the β-carbonic anhydrases (2010) Biochim. Biophys. Acta, 1804, pp. 362-373
Smith, K.S., Jakubzick, C., Whittam, T.S., Ferry, J.G., Carbonic anhydrase is an ancient enzyme widespread in prokaryotes (1999) Proc. Natl. Acad. Sci. U.S.A., 96, pp. 15184-15189
Elleuche, S., Pöggeler, S., Carbonic anhydrases in fungi (2010) Microbiology, 156, pp. 23-29
Xu, Y., Feng, L., Jeffrey, P.D., Shi, Y., Morel, F.M.M., Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms (2008) Nature, 452, pp. 56-61
Cox, E.H., McLendon, G.L., Morel, F.M.M., Lane, T.W., Prince, R.C., Pickering, I.J., George, G.N., The active site structure of Thalassiosira weissflogii carbonic anhydrase 1 (2000) Biochemistry, 39, pp. 12128-12130
Park, H., Song, B., Morel, F.M., Diversity of the cadmium-containing carbonic anhydrase in marine diatoms and natural waters (2007) Environ. Microbiol., 9, pp. 403-413
Lane, T.W., Saito, M.A., George, G.N., Pickering, I.J., Prince, R.C., Morel, F.M., Biochemistry: A cadmium enzyme from a marine diatom (2005) Nature, 435, p. 42
McGinn, P.J., Morel, F.M.M., Expression and regulation of carbonic anhydraseses in the marine diatom Thalassiosira pseudonana and in natural phytoplankton assemblages from Grat Bay, New Jersey (2008) Physiologia Plantarum, 133, pp. 78-91
Roberts, S.B., Lane, T.W., Morel, F.M.M., Carbonic anhydrase in the marine diatom Thalassiosira weissflogii (Bacillariophyceae) (1997) J. Phycol, 33, pp. 845-850
Yee, D., Morel, F.M.M., In vivo substitution of zinc by cobalt in carbonic anhydrase of a marine diatom (1996) Limnol. Oceanogr., 41, pp. 573-577
Viparelli, F., Monti, S.M., De Simone, G., Innocenti, A., Scozzafava, A., Xu, Y., Morel, F.M.M., Supuran, C.T., Inhibition of the R1 fragment of the cadmium- containg ζ class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions (2010) Bioorg. Med. Chem. Lett., 20, pp. 4745-4748
Morel, F.M.M., Milligan, A.J., Saito, M.A., Marine bioinorganic chemistry: The role of trace of metals in the oceanic cycles of major nutrients (2003) Treatise on Geochemistry, pp. 113-143. , K.K. Turekian, H.D. Holland, Elsevier Science Ltd Cambridge (UK)
Tornatore, L., Marasco, D., Dathan, N., Vitale, R.M., Benedetti, E., Papa, S., Franzoso, G., Monti, S.M., Gadd45 beta forms a homodimeric complex that binds tightly to MKK7 (2008) J. Mol. Biol., 378, pp. 97-111
Scozzafava, A., Briganti, F., Ilies, M.A., Supuran, C.T., Carbonic anhydrase inhibitors Synthesis of membrane-impermeant low molecular weight sulfonamides possessing in vivo selectivity for the membrane-bound versus the cytosolic isozymes (2000) J. Med. Chem., 43, pp. 292-300
Scozzafava, A., Menabuoni, L., Mincione, F., Briganti, F., Mincione, G., Supuran, C.T., Carbonic anhydrase inhibitors. Part 74. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: Is the tail more important than the ring? (1999) J. Med. Chem., 42, pp. 2641-2650
Supuran, C.T., Nicolae, A., Popescu, A., Carbonic anhydrase inhibitors. Part 35. Synthesis of Schiff bases derived from sulfanilamide and aromatic aldehydes: The first inhibitors with equally high affinity towards cytosolic and membrane-bound isozymes (1996) Eur. J. Med. Chem., 31, pp. 431-438
Khalifah, R.G., The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C (1971) J. Biol. Chem., 246, pp. 2561-2573
Minakuchi, T., Nishimori, I., Vullo, D., Scozzafava, A., Supuran, C.T., Molecular cloning, characterization and inhibition studies of the Rv1284 β-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate (2009) J. Med. Chem., 52, pp. 2226-2232
Güzel, O., Maresca, A., Scozzafava, A., Salman, A., Balaban, A.T., Supuran, C.T., Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial β-carbonic anhydrases Rv1284 and Rv3273 (2009) J. Med. Chem., 52, pp. 4063-4067
Joseph, P., Turtaut, F., Ouahrani-Bettache, S., Montero, J.L., Nishimori, I., Minakuchi, T., Vullo, D., Supuran, C.T., Cloning, characterization and inhibition studies of a β-carbonic anhydrase from Brucella suis (2010) J. Med. Chem., 53, pp. 2277-2285
Vullo, D., Nishimori, I., Scozzafava, A., Köhler, S., Winum, J.Y., Supuran, C.T., Inhibition studies of a β-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides (2010) Bioorg. Med. Chem. Lett., 20, pp. 2178-2182
Otwinowski, Z., Minor, W., Processing of X-ray diffraction data collected in oscillation mode (1997) Methods in Enzymology, 276, pp. 307-326. , C.W. Carter Jr. R.M. Sweet, Macromolecular Crystallography, Part A Academic Press NY
Navaza, J., Amore - An automated package for molecular replacement (1994) Acta Crystallogr. Sect. A, 50, pp. 157-163
Brünger, A.T., Adams, P.D., Clore, G.M., Delano, W.L., Gros, P., Grosse-Kunstleve, R.W., Jiang, J.S., Warren, G.L., Crystallography & NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr. Sect. D, 54, pp. 905-921
Jones, T.A., Zou, J.Y., Cowan, S.W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr. Sect. A, 47, pp. 110-119
De Vries, S.J., Van Dijk, M., Bonvin, A.M.J.J., The HADDOCK web server for data-driven biomolecular docking (2010) Nat. Protoc., 5, pp. 883-897
Karaca, E., Melquiond, A.S., De Vries, S.J., Kastritis, P.L., Bonvin, A.M., Building macromolecular assemblies by information-driven docking: Introducing the HADDOCK multibody docking server (2010) Mol. Cell. Proteomics, 9, pp. 1784-1794
Reynolds, C., Damerell, D., Jones, S., ProtorP: A protein-protein interaction analysis server (2009) Bioinformatics, 25, pp. 413-414
Koradi, R., Billeter, M., Wüthrich, K., MOLMOL: A program for display and analysis of macromolecular structures (1996) J. Mol. Graph, 14, pp. 51-55
Barrese III, A.A., Genis, C., Fisher, S.Z., Orwenyo, J.N., Kumara, M.T., Dutta, S.K., Phillips, E., Tripp, B.C., (2008) Biochemistry, 47, pp. 3174-3184
Fisher, S.Z., Maupin, C.M., Budayova-Spano, M., Govindasamy, L., Tu, C.K., Agbandje-Mckenna, M., Silverman, D.N., McKenna, R., (2007) Biochemistry, 46, pp. 2930-2937
Innocenti, A., Mühlschlegel, F.A., Hall, R.A., Steegborn, C., Scozzafava, A., Supuran, C.T., Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions (2008) Bioorg. Med. Chem. Lett., 18, pp. 5066-5070
Innocenti, A., Hall, R.A., Schlicker, C., Mühlschlegel, F.A., Supuran, C.T., Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates (2009) Bioorg. Med. Chem., 17, pp. 2654-2657
Suarez Covarrubias, A., Larsson, A.M., Hogbom, M., Lindberg, J., Bergfors, T., Bjorkelid, C., Mowbray, S.L., Jones, T.A., Structure and function of carbonic anhydrases from Mycobacterium tuberculosis (2005) J. Biol. Chem., 280, pp. 18782-18789
Cronk, J.D., Rowlett, R.S., Zhang, K.Y., Tu, C., Endrizzi, J.A., Lee, J., Gareiss, P.C., Preiss, J.R., Identification of a novel noncatalytic bicarbonate binding site in eubacterial β-carbonic anhydrase (2006) Biochemistry, 45, pp. 4351-4361
Zimmerman, S., Innocenti, A., Casini, A., Ferry, J.G., Scozzafava, A., Supuran, C.T., Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulphonamides (2004) Bioorg. Med. Chem. Lett., 14, pp. 6001-6006
Avdeef, A., Hartenstein, J.F., Chemotti, Jr.A.R., Browdb, J.A., Cadmium binding by biological ligands. 5. Solution studies of Cadmium and Zinc binding by sulfhydryl ligands N, N'-Dimethyl-N, N'-bis(2-mercaptoethyl) ethylenediaminaen d(2-mercaptoethyl1)amine (1992) Inorg. Chem., 31, pp. 3701-3705
Rosati, A.M., Traversa, U., Mechanisms of inhibitory effects of zinc and Cadmium ions on agonist binding to adenosine A1 receptors in rat brain (1999) Biochem. Pharmacol., 58, pp. 623-632
Moya, A., Tambutté, S., Bertucci, A., Tambutté, E., Lotto, S., Vullo, D., Supuran, C.T., Zoccola, D., Carbonic anhydrase in the scleractinian coral Stylophora pistillata: Characterization, localization, and role in biomineralization (2008) J. Biol. Chem., 283, pp. 25475-25484
Bertucci, A., Innocenti, A., Zoccola, D., Scozzafava, A., Tambutté, S., Supuran, C.T., Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides (2009) Bioorg. Med. Chem., 17, pp. 5054-5058
Supuran, C. T., Carbonic anhydrases: Novel therapeutic applications for inhibitors and activators (2008) Nat. Rev. Drug Discov., 7, pp. 168-181
Supuran, C. T., Scozzafava, A., Casini, A., Carbonic anhydrase inhibitors (2003) Med. Res. Rev., 23, pp. 146-189
Domsic, J. F., Avvaru, B. S., Kim, C. U., Gruner, S. M., Agbandje-Mckenna, M., Silverman, D. N., McKenna, R., Entrapment of carbon dioxide in the active site of carbonic anhydrase II (2008) J. Biol. Chem., 283, pp. 30766-30771
Lane, T. W., Morel, F. M. M., A biological function for cadmium in marine diatoms (2000) Proc. Natl. Acad. Sci. USA, 97, pp. 4627-4631
Ferry, J. F., The gamma-carbonic anhydrases (2010) Biochim. Biophys. Acta, 1804, pp. 374-381
Rowlett, R. S., Structure and catalytic mechanism of the -carbonic anhydrases (2010) Biochim. Biophys. Acta, 1804, pp. 362-373
Smith, K. S., Jakubzick, C., Whittam, T. S., Ferry, J. G., Carbonic anhydrase is an ancient enzyme widespread in prokaryotes (1999) Proc. Natl. Acad. Sci. U. S. A., 96, pp. 15184-15189
Elleuche, S., P ggeler, S., Carbonic anhydrases in fungi (2010) Microbiology, 156, pp. 23-29
Cox, E. H., McLendon, G. L., Morel, F. M. M., Lane, T. W., Prince, R. C., Pickering, I. J., George, G. N., The active site structure of Thalassiosira weissflogii carbonic anhydrase 1 (2000) Biochemistry, 39, pp. 12128-12130
Lane, T. W., Saito, M. A., George, G. N., Pickering, I. J., Prince, R. C., Morel, F. M., Biochemistry: A cadmium enzyme from a marine diatom (2005) Nature, 435, p. 42
McGinn, P. J., Morel, F. M. M., Expression and regulation of carbonic anhydraseses in the marine diatom Thalassiosira pseudonana and in natural phytoplankton assemblages from Grat Bay, New Jersey (2008) Physiologia Plantarum, 133, pp. 78-91
Roberts, S. B., Lane, T. W., Morel, F. M. M., Carbonic anhydrase in the marine diatom Thalassiosira weissflogii (Bacillariophyceae) (1997) J. Phycol, 33, pp. 845-850
Yee, D., Morel, F. M. M., In vivo substitution of zinc by cobalt in carbonic anhydrase of a marine diatom (1996) Limnol. Oceanogr., 41, pp. 573-577
Morel, F. M. M., Milligan, A. J., Saito, M. A., Marine bioinorganic chemistry: The role of trace of metals in the oceanic cycles of major nutrients (2003) Treatise on Geochemistry, pp. 113-143. , K. K. Turekian, H. D. Holland, Elsevier Science Ltd Cambridge (UK)
Supuran, C. T., Nicolae, A., Popescu, A., Carbonic anhydrase inhibitors. Part 35. Synthesis of Schiff bases derived from sulfanilamide and aromatic aldehydes: The first inhibitors with equally high affinity towards cytosolic and membrane-bound isozymes (1996) Eur. J. Med. Chem., 31, pp. 431-438
Khalifah, R. G., The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C (1971) J. Biol. Chem., 246, pp. 2561-2573
G zel, O., Maresca, A., Scozzafava, A., Salman, A., Balaban, A. T., Supuran, C. T., Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial -carbonic anhydrases Rv1284 and Rv3273 (2009) J. Med. Chem., 52, pp. 4063-4067
Br nger, A. T., Adams, P. D., Clore, G. M., Delano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Warren, G. L., Crystallography & NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr. Sect. D, 54, pp. 905-921
Jones, T. A., Zou, J. Y., Cowan, S. W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr. Sect. A, 47, pp. 110-119
De Vries, S. J., Van Dijk, M., Bonvin, A. M. J. J., The HADDOCK web server for data-driven biomolecular docking (2010) Nat. Protoc., 5, pp. 883-897
Barrese III, A. A., Genis, C., Fisher, S. Z., Orwenyo, J. N., Kumara, M. T., Dutta, S. K., Phillips, E., Tripp, B. C., (2008) Biochemistry, 47, pp. 3174-3184
Fisher, S. Z., Maupin, C. M., Budayova-Spano, M., Govindasamy, L., Tu, C. K., Agbandje-Mckenna, M., Silverman, D. N., McKenna, R., (2007) Biochemistry, 46, pp. 2930-2937
Innocenti, A., M hlschlegel, F. A., Hall, R. A., Steegborn, C., Scozzafava, A., Supuran, C. T., Carbonic anhydrase inhibitors. Inhibition of the -class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions (2008) Bioorg. Med. Chem. Lett., 18, pp. 5066-5070
Cronk, J. D., Rowlett, R. S., Zhang, K. Y., Tu, C., Endrizzi, J. A., Lee, J., Gareiss, P. C., Preiss, J. R., Identification of a novel noncatalytic bicarbonate binding site in eubacterial -carbonic anhydrase (2006) Biochemistry, 45, pp. 4351-4361
Rosati, A. M., Traversa, U., Mechanisms of inhibitory effects of zinc and Cadmium ions on agonist binding to adenosine A1 receptors in rat brain (1999) Biochem. Pharmacol., 58, pp. 623-632
Moya, A., Tambutt, S., Bertucci, A., Tambutt, E., Lotto, S., Vullo, D., Supuran, C. T., Zoccola, D., Carbonic anhydrase in the scleractinian coral Stylophora pistillata: Characterization, localization, and role in biomineralization (2008) J. Biol. Chem., 283, pp. 25475-25484
Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii