Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein(357 views) Vagliasindi LI, Arena G, Bonomo RP, Pappalardo G, Tabbì G
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2011 Mar 21; 40(11): 2441-2450.
Dipartimento di Scienze Chimiche, Università Degli Studi di Catania, Viale A. Doria 6, 95125, Catania, Italy
Consorzio Interuniversitario C.I.R.C.S.M.B., Via C. Ulpiani 27, 70125, Bari, Italy
Istituto di Biostrutture e Bioimmagini, CNR, U.O.S. di Catania, Viale A. Doria 6, 95125, Catania, Italy
Łuczkowski, M., Kozlowski, H., Stawikowski, M., Rolka, K., Gaggelli, E., Valensin, D., Valensin, G., (2002) J. Chem. Soc., Dalton Trans., p. 2269
Brown, D.R., Kozlowski, H., (2004) Dalton Trans., p. 1907
Bonomo, R.P., La Mendola, D., Pappalardo, G., Rizzarelli, E., Sóvágó, I., (2006) Recent Development in Bioinorganic Chemistry: Metal Complexes of Bioactive Molecules, , M. Saviano (ed), Kerala, Chapter 6
Kozlowski, H., Janicka-Klos, A., Stanczak, P., Valensin, D., Valensin, G., Kulon, K., (2008) Coord. Chem. Rev., 252, p. 1069
Gustiananda, M., Haris, P.I., Milburn, P.J., Gready, J.E., (2002) FEBS Lett., 512, p. 38
Gustiananda, M., Liggins, J.R., Cummins, P.L., Gready, J.E., (2004) Biophys. J., 86, p. 2467
Valensin, D., Gajda, K., Gralka, E., Valensin, G., Kamysz, W., Kozlowski, H., (2010) J. Inorg. Biochem., 104, p. 71
Stańczak, P., Łuczkowski, M., Juszczyk, P., Grzonka, Z., Kozłowski, H., (2004) Dalton Trans., 14, p. 2102
Kawano, T., (2007) Int. J. Biol. Sci., 3, p. 57
La Mendola, D., Bonomo, R.P., Impellizzeri, G., MacCarrone, G., Pappalardo, G., Pietropaolo, A., Rizzarelli, E., Zito, V., (2005) JBIC, J. Biol. Inorg. Chem., 10, p. 463
Windl, O., Dempster, M., Estibeiro, P., Lathe, R., (1995) Gene, 159, p. 181
Pettit, L.D., Robbins, R.A., (1995) Handbook of Metal-ligand Interactions in Biological Fluids, pp. 636-656. , G. Berthon (ed) Dekker, New York
Bonomo, R.P., Cucinotta, V., Giuffrida, A., Impellizzeri, G., Magrì, A., Pappalardo, G., Rizzarelli, E., Vagliasindi, L.I., (2005) Dalton Trans., p. 150
Damante, C.A., Ösz, K., Nagy, Z., Pappalardo, G., Grasso, G., Impellizzeri, G., Rizzarelli, E., Sóvágó, I., (2008) Inorg. Chem., 47, p. 9669
Arena, G., Calì, R., Rizzarelli, E., Sammartano, S., (1976) Thermochim. Acta, 16, p. 315
Bonomo, R.P., Calì, R., Cucinotta, V., Impellizzeri, G., Rizzarelli, E., (1986) Inorg. Chem., 25, p. 1641
Gans, P., Sabatini, A., Vacca, A., (1996) Talanta, 43, p. 1739
Alderighi, L., Gans, P., Ienco, A., Peters, D., Sabatini, A., Vacca, A., (1999) Coord. Chem. Rev., 184, p. 311
Bonomo, R.P., Pappalardo, G., Rizzarelli, E., Santoro, A.M., Tabbì, G., Vagliasindi, L.I., (2007) Dalton Trans., p. 1400
Lund, A., Vanngard, T., (1969) J. Chem. Phys., 50, p. 2979
Kaifer, A.E., Bard, J., (1985) J. Phys. Chem., 89, p. 4879
Joszai, V., Nagy, Z., Osz, K., Sanna, D., Di Natale, G., La Mendola, D., Pappalardo, G., Sovago, I., (2006) J. Inorg. Biochem., 100, p. 1399
Bonomo, R.P., Riggi, F., Di Bilio, A.J., (1988) Inorg. Chem., 27, p. 2510
Garnett, A.P., Viles, J.H., (2003) J. Biol. Chem., 278, p. 6795
Sundberg, R.J., Martin, R.B., (1974) Chem. Rev., 74, p. 471
Sigel, H., Martin, R.B., (1982) Chem. Rev., 82, p. 385
Tsangaris, J.M., Chang, J.W., Martin, R.B., (1969) J. Am. Chem. Soc., 91, p. 726
Fawcett, T.G., Bernarducci, E.E., Krough-Jespersen, K., Schugar, H.J., (1980) J. Am. Chem. Soc., 102, p. 2598
La Mendola, D., Magrì, A., Vagliasindi, L.I., Bonomo, R.P., Rizzarelli, E., (2010) Dalton Trans., 39, p. 10678
Premzl, M., Delbridge, M., Gready, J.E., Wilson, P., Johnson, M., Davis, J., Kuczek, E., Marshall Graves, J.A., (2005) Gene, 349, p. 121
Opazo, C., Barr a, M. I., Ruiz, F. H., Inestrosa, N. C., (2003) BioMetals, 16, p. 9
Brown, D. R., Besinger, A., (1998) Biochem. J., 334, p. 423
Brown, D. R., Wong, B. S., Hafiz, F., Clive, C., Haswell, S. J., Jones, M., (1999) Biochem. J., 344, p. 1
Brown, D. R., (2001) Brain Res. Bull., 55, p. 165
Jackson, G. S., Murray, I., Hosszu, L. L., Gibbs, N., Waltho, J. P., Clarke, A. R., Collinge, J., (2001) Proc. Natl. Acad. Sci. U. S. A., 98, p. 8531
Smith, C. J., Drake, A. F., Banfield, B. A., Bloomberg, G. B., Palmer, M. S., Clarke, A. R., Collinge, J., (1997) FEBS Lett., 405, p. 378
Hornshaw, M. P., McDermott, J. R., Candy, J. M., (1995) Biochem. Biophys. Res. Commun., 207, p. 621
Viles, J. H., Cohen, F. E., Prusiner, S. B., Goodin, D. B., Wright, P. E., Dyson, H. J., (1999) Proc. Natl. Acad. Sci. U. S. A., 96, p. 2042
Whittal, R. M., Ball, H. L., Cohen, F. E., Burlingame, A. L., Prusiner, S. B., Baldwin, M. A., (2000) Protein Sci., 9, p. 332
Burns, C. S., Aronoff-Spencer, E., Dunham, C. M., Lario, P., Avdievich, N. I., Antholine, W. E., Olmstead, M. M., Millhauser, G. L., (2002) Biochemistry, 41, p. 3991
uczkowski, M., Kozlowski, H., Stawikowski, M., Rolka, K., Gaggelli, E., Valensin, D., Valensin, G., (2002) J. Chem. Soc., Dalton Trans., p. 2269
Brown, D. R., Kozlowski, H., (2004) Dalton Trans., p. 1907
Bonomo, R. P., La Mendola, D., Pappalardo, G., Rizzarelli, E., S v g, I., (2006) Recent Development in Bioinorganic Chemistry: Metal Complexes of Bioactive Molecules, , M. Saviano (ed), Kerala, Chapter 6
Sta czak, P., uczkowski, M., Juszczyk, P., Grzonka, Z., Koz owski, H., (2004) Dalton Trans., 14, p. 2102
Pettit, L. D., Robbins, R. A., (1995) Handbook of Metal-ligand Interactions in Biological Fluids, pp. 636-656. , G. Berthon (ed) Dekker, New York
Bonomo, R. P., Cucinotta, V., Giuffrida, A., Impellizzeri, G., Magr, A., Pappalardo, G., Rizzarelli, E., Vagliasindi, L. I., (2005) Dalton Trans., p. 150
Damante, C. A., sz, K., Nagy, Z., Pappalardo, G., Grasso, G., Impellizzeri, G., Rizzarelli, E., S v g, I., (2008) Inorg. Chem., 47, p. 9669
Arena, G., Cal, R., Rizzarelli, E., Sammartano, S., (1976) Thermochim. Acta, 16, p. 315
Bonomo, R. P., Cal, R., Cucinotta, V., Impellizzeri, G., Rizzarelli, E., (1986) Inorg. Chem., 25, p. 1641
Bonomo, R. P., Pappalardo, G., Rizzarelli, E., Santoro, A. M., Tabb, G., Vagliasindi, L. I., (2007) Dalton Trans., p. 1400
Kaifer, A. E., Bard, J., (1985) J. Phys. Chem., 89, p. 4879
Bonomo, R. P., Riggi, F., Di Bilio, A. J., (1988) Inorg. Chem., 27, p. 2510
Garnett, A. P., Viles, J. H., (2003) J. Biol. Chem., 278, p. 6795
Dong, S. L., Cadamuro, S. A., Fiorino, F., Bertsch, U., Moroder, L., Renner, C., (2007) Biopolymers, 88, p. 840
Sundberg, R. J., Martin, R. B., (1974) Chem. Rev., 74, p. 471
Tsangaris, J. M., Chang, J. W., Martin, R. B., (1969) J. Am. Chem. Soc., 91, p. 726
Fawcett, T. G., Bernarducci, E. E., Krough-Jespersen, K., Schugar, H. J., (1980) J. Am. Chem. Soc., 102, p. 2598
Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein
A spectroscopic (UV-Vis, CD and EPR), thermodynamic and voltammetric study of the copper(II) complexes with the Ac-PHPGGSNWGQ-NH(2) polypeptide (L), a fragment of the opossum PrP protein N-terminal four-repeat region, was carried out in aqueous solution. It suggests the formation of a highly distorted [Cu(L)H(-2)] complex species in the neutral region, the stereochemistry of which is ascribable to a square base pyramid and a CuN(3)O(2) chromophore, resulting from the coordination of a histidine imidazole and two peptide nitrogen atoms and probably oxygen atoms from water molecules. At basic pH values a [Cu(L)H(-3)](-) species with a pseudo-octahedral geometry was also obtained, with four nitrogen donor atoms in its equatorial plane, coming from the histidine residue and from peptidic nitrogen atoms. Interestingly, at pH values relatively higher than the neutrality, the coordination sphere of the copper complex in the [Cu(L)H(-2)] species changes its stereochemistry towards a pseudo-octahedron, as suggested by the change in the parallel copper hyperfine coupling constant of the EPR spectra at low temperature. A slight difference in the redox potentials between this two-faced [Cu(L)H(-2)] complex species seems to confirm this behaviour. Both potentiometric and spectroscopic data were compared with the analogous species obtained with the Ac-PHGGGWGQ-NH(2) peptide, belonging to the octarepeat domain of the human prion protein (hPrP) N-terminal region. The [Cu(L)H(-2)] species formed by the Ac-PHPGGSNWGQ-NH(2) decapeptide, having a slightly lower stability, turned out to be less abundant and to exist within a narrow pH range.
Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein
No results.
Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein
Kállay C, Dávid A, Timári S, Nagy EM, Sanna D, Garribba E, Micera G, De Bona P, Pappalardo G, Rizzarelli E, Sóvágó I * Copper(II) complexes of rat amylin fragments(357 views) Dalton T (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2011 Oct 14; 40(38): 9711-9721. Impact Factor:3.838 ViewExport to BibTeXExport to EndNote