Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis(453 views) D'Ambrosio K, Lopez M, Dathan NA, Ouahrani-bettache S, Köhler S, Ascione G, Monti SM, Winum JY, De Simone G
Istituto di Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, 80134 Napoli, Italy
Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-UM1-UM2, Ecole Nationale Supérieure de Chimie de Montpellier, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex, France
Centre d'Etudes d'Agents Pathogènes et Biotechnologies Pour la Santé (CPBS), UMR 5236 CNRS-UM1-UM2, 1919 Route de Mende, 34293 Montpellier, France
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Abdo, M.R., Joseph, P., Boigegrain, R.A., Liautard, J.P., Montero, J.L., Köhler, S., Winum, J.Y., Brucella suis histidinol dehydrogenase: Synthesis and inhibition studies of a series of substituted benzylic ketones derived from histidine (2007) Bioorg. Med. Chem., 15, pp. 4427-4433
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Rossmann, M.G., Liljas, A., Brandén, C.I., Banaszak, L.J., Lactate dehydrogenase (1975) The Enzymes, VOL. XI., pp. 61-102. , third ed. P.D. Boyer, Academic Press New York
Furtado, G. H., Nicolau, D. P., Overview perspective of bacterial resistance (2010) Expert Opin. Ther. Pat., 20, pp. 1273-127
Ginsberg, A. M., Emerging drugs for active tuberculosis (2008) Semin. Respir. Crit. Care Med., 29, pp. 552-559
Nickerson, C. A., Schurr, M. J., (2006) Molecular Paradigms of Infectious Disease: A Bacterial Perspective, pp. 1-617. , Springer Verlag Munich
Rasko, D. A., Sperandio, V., Anti-virulence strategies to combat bacteria-mediated disease (2010) Nat. Rev. Drug Discov., 9, pp. 117-128
Abdo, M. R., Joseph, P., Boigegrain, R. A., Liautard, J. P., Montero, J. L., K hler, S., Winum, J. Y., Brucella suis histidinol dehydrogenase: Synthesis and inhibition studies of a series of substituted benzylic ketones derived from histidine (2007) Bioorg. Med. Chem., 15, pp. 4427-4433
K hler, S., Michaux-Charachon, S., Porte, F., Ramuz, M., Liautard, J. P., What is the nature of the replicative niche of a stealthy bug named Brucella? (2003) Trends Microbiol., 11, pp. 215-219
K hler, S., Foulongne, V., Ouahrani-Bettache, S., Bourg, G., Teyssier, J., Ramuz, M., Liautard, J. P., The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell (2002) Proc. Natl. Acad. Sci. U. S. A., 99, pp. 15711-15716
Delrue, R. M., Lestrate, P., Tibor, A., Letesson, J. J., De Bolle, X., Brucella pathogenesis, genes identified from random large-scale screens (2004) FEMS Microbiol. Lett., 231, pp. 1-12
Lopez, M., K hler, S., Winum, J. Y., Zinc metalloenzymes as new targets against the bacterial pathogen Brucella (2012) J. Inorg. Biochem., 111, pp. 138-145
Grubmeyer, C. T., Insinga, S., Bhatia, M., Moazami, N., Salmonella typhimurium histidinol dehydrogenase: Complete reaction stereochemistry and active site mapping (1989) Biochemistry, 28, pp. 8174-8180
Barbosa, J. A. R. G., Sivaraman, J., Li, Y., Larocque, R., Matte, A., Schrag, J. D., Cygler, M., Mechanism of action and NAD+ binding mode revealed by the crystal structure of l-histidinol dehydrogenase (2002) Proc. Natl. Acad. Sci. U. S. A., 99, pp. 1859-1864
Brunger, A. T., Adams, P. D., Clore, G. M., De Lano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Warren, G. L., Crystallography & NMR system: A new software suite for macromolecular structure determination (1998) Acta Crystallogr., 54 D, pp. 905-921
Laskowski, R. A., MacArthur, M. W., Moss, D. S., Thornton, J. M., PROCHECK: A program to check the stereochemical quality of protein structures (1993) J. Appl. Crystallogr., 26, pp. 283-291
Jones, T. A., Zou, J. Y., Cowan, S. W., Kjeldgaard, M., Improved methods for building protein models in electron density maps and the location of errors in these models (1991) Acta Crystallogr., 47 A, pp. 110-119
Rossmann, M. G., Liljas, A., Brand n, C. I., Banaszak, L. J., Lactate dehydrogenase (1975) The Enzymes, VOL. XI., pp. 61-102. , third ed. P. D. Boyer, Academic Press New York
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis