Convenient synthesis of lactuloselysine and its use for LC-MS analysis in milk-like model systems (331 views visite)
J Agric Food Chem (ISSN: 0021-8561), 1999 Nov; 47(11): 4700-4706.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 1.453, 5-year impact factor Impact factor a 5 anni: 3.172
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033230062&partnerID=40&md5=379cdd87ca7094bda3e67938cc598c8c
Keywords Parole chiave: Lactuloselysine, Lc-Ms, Maillard Reaction, Milklike Model Systems, Drug Derivative, Epsilon-N-1-(1-Deoxylactulosyl)lysine, Lactose, Milk Protein, Selenium Derivative, Unclassified Drug, Whey Protein, Animal, Article, Chemical Reaction, Chemistry, Food Processing, Food Quality, Glycation, Liquid Chromatography, Mass Spectrometry, Nutritional Value, Synthesis, Epsilon-N-1- (1-Deoxylactulosyl) Lysine,
Affiliations Affiliazioni:
Dipto. di Scienza degli Alimenti, Univ. Studi di Napoli Federico II, Parco Gussone, 80055 Portici, Napoli, Italy
References Riferimenti:
Aschaffenburg, R., Dewry, J., New procedure for routine determination of various noncasein proteins of milk (1959) 15th Int. Dairy Congr. Lond., 3, pp. 1631-163
Badoud, R., Fay, L., Richli, U., Husek, P., Gas-chromatography determination of n-carboxymethyl amino acids, the periodate oxidation products of amadori compounds (1991) J. Chromatogr., 552, pp. 345-351
Berg, H.E., Van Boekel, M.A.J.S., Degratation of lactose during heating of milk. 1 reaction pathways (1994) Netherland Milk Dairy J., 48, pp. 157-175
Burton, H., Reviews of the progress of dairy science. The bacteriological, chemical, biochemical and physical changes that can occur in milk at temperatures of 100-150°C (1984) J. Dairy Res., 51, pp. 341-363
Carpino, L.A., Han, G.Y., The 9-fluorenylmethoxycarbonyl amino-protecting group (1972) J. Org. Chem., 37, pp. 3404-3409
Corradini, C., Le proteine (1995) Chimica e Tecnologia del Latte, , Tecniche nuove ed.
Erbersdobler, H.F., Twenty years of furosine - Better knowledge about the biological significance of Maillard reaction in food and nutrition (1985) Proceedings of the 3rd International Symposium on the Maillard Reaction: "Amino-carbonyl Reaction in Food and Biological Systems", , Fuji Institute, Japan
Fujimaki, M., Namiki, M., Kato, H., (1986) Development in Food Science, 13, pp. 481-491. , Elsevier Science Publishers: Amsterdam, and Kodansha Ltd.: Tokyo
Finot, P.A., Metabolism and physiological effects of maillard reaction products (1990) The Maillard Reaction in Food Processing, Human Nutrition and Physiology, , Finot, P. A., Aeschbacher, H., Hurrel, R. F., Liardon, R., Eds.
Birgansen Verlang: Basel
Finot, P.A., Deutsch, R., Bujard, E., The exent of the maillard reaction during the processing of milk (1981) Prog. Fd. Nutr. Sci., 5, pp. 345-355
Finot, P.A., Mauron, J., Le blocage de la lysine par la réaction de Maillard. I. Synthèse de N-(désoxy-1-D-fructosil-1-) et N-(désoxy-1-D-lactulosil-1-)-L-lysine (1969) Helv. Chim. Acta, 52, pp. 1488-1495
Fogliano, V., Monti, S.M., Ritieni, A., Marchisano, C., Peluso, G., Randazzo, G., An immunological approach to monitor protein lactosylation of heated food model system (1997) Food Chem., 58, pp. 53-58
Friedmann, M., Food brownig and its prevention: An overview (1996) J. Agric. Food. Chem., 44, pp. 631-653
Friedmann, M., The impact of the Maillard reaction on the nutritional value of food proteins (1996) The Maillard Rection: Conseguences for the Chemical and Life Sciences, , Ihan, R., Ed.
Wiley and Sons: New York
Furth, A., J. Methods for assaying nonenzymatic glycosylation (1988) Analit. Biochem., 175, pp. 347-360
Henle, T., Walter, H., Klostermeyer, H., Evalutation of the extent of the early maillard-reaction in milk products by direct measurement of the Amadori-product lactuloselysine (1991) Z. Lebensm. Unters. Forsch., 193, pp. 119-122
Mauron, J., The Maillard reaction in food: A critical review from the nutritional standpoint (1981) Prog. Fd. Nutr. Sci., 5, pp. 5-35
Monti, S.M., Bailey, R.G., Ames, J.M., The influence of pH on the non-volatile reaction products of aqueous maillard model systems by HPLC with diode array detection (1998) Food Chem., 62, pp. 369-375
Morales, F.J., Jemenez Perez, S., Study of HMF formed from acid degradation of the A.P. In milk resembling system (1998) J. Agric. Food. Chem., 46, pp. 3885-3890
Olano, A., Santa-Maria, G., Corzo, N., Calvo, M.M., Martines-Castro, I., Jimeno, M.L., Determination of free carbohydrates and Amadori compounds formed at the early stages of nonenzymic browning (1992) Food Chem., 43, pp. 351-358
Pellegrino, L., Resmini, P., Luf, W., Assestement (indices) of heat treatment of milk (1995) Heat-induced Changes in Milk, , Fox, P. F., Ed.
International Dairy Federation: Brussels
Pizzano, R., Nicolai, M.A., Siciliano, R., Addeo, F., Specific deletion of the Amadori compounds in milk by using polyclonal antibodies raised against a lactosylated peptide (1998) J. Agric. Food Chem., 46, pp. 5373-5379
Porretta, S., Chromatographic analysis of maillard reaction products (1992) J. Chromatogr., 624, pp. 211-219
Resmini, P., Pellegrino, L., Batelli, G., Accurate quantification of furosine in milk and dairy products by a direct HPLC method (1990) Italian J. Food Sci., 3, pp. 173-183
Schreuder, H.A., Welling, G.W., Determination of β-galactosidase activity in the intestinal tract of mice by ion-exchange high-performance liquid chromatography using ∈-N-1-(1-deoxylactulosil)-L-lysine as substrate (1983) J. Chromatoer., 278, pp. 275-282
Berg, H. E., Van Boekel, M. A. J. S., Degratation of lactose during heating of milk. 1 reaction pathways (1994) Netherland Milk Dairy J., 48, pp. 157-175
Carpino, L. A., Han, G. Y., The 9-fluorenylmethoxycarbonyl amino-protecting group (1972) J. Org. Chem., 37, pp. 3404-3409
Erbersdobler, H. F., Twenty years of furosine - Better knowledge about the biological significance of Maillard reaction in food and nutrition (1985) Proceedings of the 3rd International Symposium on the Maillard Reaction: "Amino-carbonyl Reaction in Food and Biological Systems", , Fuji Institute, Japan
Finot, P. A., Metabolism and physiological effects of maillard reaction products (1990) The Maillard Reaction in Food Processing, Human Nutrition and Physiology, , Finot, P. A., Aeschbacher, H., Hurrel, R. F., Liardon, R., Eds.
Finot, P. A., Deutsch, R., Bujard, E., The exent of the maillard reaction during the processing of milk (1981) Prog. Fd. Nutr. Sci., 5, pp. 345-355
Finot, P. A., Mauron, J., Le blocage de la lysine par la r action de Maillard. I. Synth se de N- (d soxy-1-D-fructosil-1-) et N- (d soxy-1-D-lactulosil-1-) -L-lysine (1969) Helv. Chim. Acta, 52, pp. 1488-1495
Monti, S. M., Bailey, R. G., Ames, J. M., The influence of pH on the non-volatile reaction products of aqueous maillard model systems by HPLC with diode array detection (1998) Food Chem., 62, pp. 369-375
Morales, F. J., Jemenez Perez, S., Study of HMF formed from acid degradation of the A. P. In milk resembling system (1998) J. Agric. Food. Chem., 46, pp. 3885-3890
Schreuder, H. A., Welling, G. W., Determination of -galactosidase activity in the intestinal tract of mice by ion-exchange high-performance liquid chromatography using -N-1- (1-deoxylactulosil) -L-lysine as substrate (1983) J. Chromatoer., 278, pp. 275-282
J Agric Food Chem (ISSN: 0021-8561), 1999 Nov; 47(11): 4700-4706.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 1.453, 5-year impact factor Impact factor a 5 anni: 3.172
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033230062&partnerID=40&md5=379cdd87ca7094bda3e67938cc598c8c
Keywords Parole chiave: Lactuloselysine, Lc-Ms, Maillard Reaction, Milklike Model Systems, Drug Derivative, Epsilon-N-1-(1-Deoxylactulosyl)lysine, Lactose, Milk Protein, Selenium Derivative, Unclassified Drug, Whey Protein, Animal, Article, Chemical Reaction, Chemistry, Food Processing, Food Quality, Glycation, Liquid Chromatography, Mass Spectrometry, Nutritional Value, Synthesis, Epsilon-N-1- (1-Deoxylactulosyl) Lysine,
Affiliations Affiliazioni:
Dipto. di Scienza degli Alimenti, Univ. Studi di Napoli Federico II, Parco Gussone, 80055 Portici, Napoli, Italy
References Riferimenti:
Aschaffenburg, R., Dewry, J., New procedure for routine determination of various noncasein proteins of milk (1959) 15th Int. Dairy Congr. Lond., 3, pp. 1631-163
Badoud, R., Fay, L., Richli, U., Husek, P., Gas-chromatography determination of n-carboxymethyl amino acids, the periodate oxidation products of amadori compounds (1991) J. Chromatogr., 552, pp. 345-351
Berg, H.E., Van Boekel, M.A.J.S., Degratation of lactose during heating of milk. 1 reaction pathways (1994) Netherland Milk Dairy J., 48, pp. 157-175
Burton, H., Reviews of the progress of dairy science. The bacteriological, chemical, biochemical and physical changes that can occur in milk at temperatures of 100-150°C (1984) J. Dairy Res., 51, pp. 341-363
Carpino, L.A., Han, G.Y., The 9-fluorenylmethoxycarbonyl amino-protecting group (1972) J. Org. Chem., 37, pp. 3404-3409
Corradini, C., Le proteine (1995) Chimica e Tecnologia del Latte, , Tecniche nuove ed.
Erbersdobler, H.F., Twenty years of furosine - Better knowledge about the biological significance of Maillard reaction in food and nutrition (1985) Proceedings of the 3rd International Symposium on the Maillard Reaction: "Amino-carbonyl Reaction in Food and Biological Systems", , Fuji Institute, Japan
Fujimaki, M., Namiki, M., Kato, H., (1986) Development in Food Science, 13, pp. 481-491. , Elsevier Science Publishers: Amsterdam, and Kodansha Ltd.: Tokyo
Finot, P.A., Metabolism and physiological effects of maillard reaction products (1990) The Maillard Reaction in Food Processing, Human Nutrition and Physiology, , Finot, P. A., Aeschbacher, H., Hurrel, R. F., Liardon, R., Eds.
Birgansen Verlang: Basel
Finot, P.A., Deutsch, R., Bujard, E., The exent of the maillard reaction during the processing of milk (1981) Prog. Fd. Nutr. Sci., 5, pp. 345-355
Finot, P.A., Mauron, J., Le blocage de la lysine par la réaction de Maillard. I. Synthèse de N-(désoxy-1-D-fructosil-1-) et N-(désoxy-1-D-lactulosil-1-)-L-lysine (1969) Helv. Chim. Acta, 52, pp. 1488-1495
Fogliano, V., Monti, S.M., Ritieni, A., Marchisano, C., Peluso, G., Randazzo, G., An immunological approach to monitor protein lactosylation of heated food model system (1997) Food Chem., 58, pp. 53-58
Friedmann, M., Food brownig and its prevention: An overview (1996) J. Agric. Food. Chem., 44, pp. 631-653
Friedmann, M., The impact of the Maillard reaction on the nutritional value of food proteins (1996) The Maillard Rection: Conseguences for the Chemical and Life Sciences, , Ihan, R., Ed.
Wiley and Sons: New York
Furth, A., J. Methods for assaying nonenzymatic glycosylation (1988) Analit. Biochem., 175, pp. 347-360
Henle, T., Walter, H., Klostermeyer, H., Evalutation of the extent of the early maillard-reaction in milk products by direct measurement of the Amadori-product lactuloselysine (1991) Z. Lebensm. Unters. Forsch., 193, pp. 119-122
Mauron, J., The Maillard reaction in food: A critical review from the nutritional standpoint (1981) Prog. Fd. Nutr. Sci., 5, pp. 5-35
Monti, S.M., Bailey, R.G., Ames, J.M., The influence of pH on the non-volatile reaction products of aqueous maillard model systems by HPLC with diode array detection (1998) Food Chem., 62, pp. 369-375
Morales, F.J., Jemenez Perez, S., Study of HMF formed from acid degradation of the A.P. In milk resembling system (1998) J. Agric. Food. Chem., 46, pp. 3885-3890
Olano, A., Santa-Maria, G., Corzo, N., Calvo, M.M., Martines-Castro, I., Jimeno, M.L., Determination of free carbohydrates and Amadori compounds formed at the early stages of nonenzymic browning (1992) Food Chem., 43, pp. 351-358
Pellegrino, L., Resmini, P., Luf, W., Assestement (indices) of heat treatment of milk (1995) Heat-induced Changes in Milk, , Fox, P. F., Ed.
International Dairy Federation: Brussels
Pizzano, R., Nicolai, M.A., Siciliano, R., Addeo, F., Specific deletion of the Amadori compounds in milk by using polyclonal antibodies raised against a lactosylated peptide (1998) J. Agric. Food Chem., 46, pp. 5373-5379
Porretta, S., Chromatographic analysis of maillard reaction products (1992) J. Chromatogr., 624, pp. 211-219
Resmini, P., Pellegrino, L., Batelli, G., Accurate quantification of furosine in milk and dairy products by a direct HPLC method (1990) Italian J. Food Sci., 3, pp. 173-183
Schreuder, H.A., Welling, G.W., Determination of β-galactosidase activity in the intestinal tract of mice by ion-exchange high-performance liquid chromatography using ∈-N-1-(1-deoxylactulosil)-L-lysine as substrate (1983) J. Chromatoer., 278, pp. 275-282
Berg, H. E., Van Boekel, M. A. J. S., Degratation of lactose during heating of milk. 1 reaction pathways (1994) Netherland Milk Dairy J., 48, pp. 157-175
Carpino, L. A., Han, G. Y., The 9-fluorenylmethoxycarbonyl amino-protecting group (1972) J. Org. Chem., 37, pp. 3404-3409
Erbersdobler, H. F., Twenty years of furosine - Better knowledge about the biological significance of Maillard reaction in food and nutrition (1985) Proceedings of the 3rd International Symposium on the Maillard Reaction: "Amino-carbonyl Reaction in Food and Biological Systems", , Fuji Institute, Japan
Finot, P. A., Metabolism and physiological effects of maillard reaction products (1990) The Maillard Reaction in Food Processing, Human Nutrition and Physiology, , Finot, P. A., Aeschbacher, H., Hurrel, R. F., Liardon, R., Eds.
Finot, P. A., Deutsch, R., Bujard, E., The exent of the maillard reaction during the processing of milk (1981) Prog. Fd. Nutr. Sci., 5, pp. 345-355
Finot, P. A., Mauron, J., Le blocage de la lysine par la r action de Maillard. I. Synth se de N- (d soxy-1-D-fructosil-1-) et N- (d soxy-1-D-lactulosil-1-) -L-lysine (1969) Helv. Chim. Acta, 52, pp. 1488-1495
Monti, S. M., Bailey, R. G., Ames, J. M., The influence of pH on the non-volatile reaction products of aqueous maillard model systems by HPLC with diode array detection (1998) Food Chem., 62, pp. 369-375
Morales, F. J., Jemenez Perez, S., Study of HMF formed from acid degradation of the A. P. In milk resembling system (1998) J. Agric. Food. Chem., 46, pp. 3885-3890
Schreuder, H. A., Welling, G. W., Determination of -galactosidase activity in the intestinal tract of mice by ion-exchange high-performance liquid chromatography using -N-1- (1-deoxylactulosil) -L-lysine as substrate (1983) J. Chromatoer., 278, pp. 275-282
Convenient synthesis of lactuloselysine and its use for LC-MS analysis in milk-like model systems
The synthesis of the Amadori product lactuloselysine [N(ε)(1-deoxy-D- lactulosyl-1)-L-lysine] was obtained starting from FMOC-lysine-OH (N(α)-9- fluorenylmethoxy-carbonyl-N(ε)H2-L-lysine-OH) and lactose. Compound identity was confirmed by MALDI-ToF, electrospray, and NMR analysis. A selective LC-MS procedure which allowed the detection of lactuloselysine up to 10 ng mL-1 was set up and used to follow the formation of the compound in a lactose-lysine model system; quantification of this molecule after complete enzymatic hydrolysis of whey-proteins from milk samples was also performed.
The synthesis of the Amadori product lactuloselysine [N(ε)(1-deoxy-D- lactulosyl-1)-L-lysine] was obtained starting from FMOC-lysine-OH (N(α)-9- fluorenylmethoxy-carbonyl-N(ε)H2-L-lysine-OH) and lactose. Compound identity was confirmed by MALDI-ToF, electrospray, and NMR analysis. A selective LC-MS procedure which allowed the detection of lactuloselysine up to 10 ng mL-1 was set up and used to follow the formation of the compound in a lactose-lysine model system; quantification of this molecule after complete enzymatic hydrolysis of whey-proteins from milk samples was also performed.
Convenient synthesis of lactuloselysine and its use for LC-MS analysis in milk-like model systems
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Convenient synthesis of lactuloselysine and its use for LC-MS analysis in milk-like model systems
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Vergara A, Vitagliano L, Verde C, di Prisco G, Mazzarella L
* Spectroscopic and crystallographic characterization of bis-histidyl adducts in tetrameric hemoglobins (383 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 2008; 436: 425-444.
Impact Factor: 2.312
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (419 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
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D'Auria S, Varriale A, Gonnelli M, Saviano M, Staiano M, Rossi M, Strambini GB
* Tryptophan phosphorescence studies of the D-galactose/ D-glucose-binding protein from Escherichia coli provide a molecular portrait with structural and dynamics features of the protein (522 visite)
J Proteome Res (ISSN: 1535-3893), 2007; 6(4): 1306-1312.
Impact Factor: 5.675
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Pailot A, D'Ambrosio K, Corbier C, Talfournier F, Branlant G
* Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans (302 visite)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2006 Dec 15; 400: 521-530.
Impact Factor: 4.1
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De Luca S, Saviano M, Della Moglie R, Digilio G, Bracco C, Aloj L, Tarallo L, Pedone C, Morelli G
* Conformationally constrained CCK8 analogues obtained from a rationally designed peptide library as ligands for cholecystokinin type B receptor (386 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2006 Sep; 1(9): 997-1006.
Impact Factor: 3.046
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Nuernberger P, Vogt G, Gerber G, Improta R, Santoro F
* Femtosecond study on the isomerization dynamics of NK88. I. Ground-state dynamics after photoexcitation (330 visite)
J Chem Phys (ISSN: 0021-9606, 0021-9606print, 0897-690online), 2006 Jul 28; 125(4): 44512-44544.
Impact Factor: 3.247
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Vogt G, Nuernberger P, Gerber G, Improta R, Santoro F, Nuernberger P, Vogt G, Gerber G, Improta R, Santoro F
* Femtosecond study on the isomerization dynamics of NK88. II. Excited-state dynamics (312 visite)
J Chem Phys (ISSN: 0021-9606, 0897-690online), 2006 Jul 28; 125(4): 44512-44512.
Impact Factor: 3.166
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D'Agata R, Grasso G, Iacono G, Spoto G, Vecchio G
* Lectin recognition of a new SOD mimic bioconjugate studied with surface plasmon resonance imaging (273 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2006 Feb 21; 4(4): 610-612.
Impact Factor: 2.874
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Saviano M, Improta R, Benedetti E, Carrozzini B, Cascarano GL, Didierjean C, Toniolo C, Crisma M
* Benzophenone photophore flexibility and proximity: Molecular and crystal-state structure of a Bpa-containing trichogin dodecapeptide analogue (365 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Apr 2; 5(4): 541-544.
Impact Factor: 3.474
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Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
* In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (541 visite)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2004 Mar; 45(3): 485-494.
Impact Factor: 5.362
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (262 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Camera L, Del Vecchio S, Quarantelli M, Ibello F, Pellegrino T, Salvatore M
* Radiolabeled somatostatin analogs in the diagnosis and staging of neuroendocrine tumors (312 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2003; 26(8Suppl): 60-62.
Impact Factor: 1.621
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Vitaglione P, Monti SM, Ambrosino P, Skog K, Fogliano V
* Carotenoids from tomatoes inhibit heterocyclic amine formation (192 visite)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(2): 108-113.
Impact Factor: 1.021
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Formaggio F, Bonchio M, Crisma M, Peggion C, Mezzato S, Polese A, Barazza A, Antonello S, Maran F, Broxterman QB, Kaptein B, Kamphuis J, Vitale RM, Saviano M, Benedetti E, Toniolo C
* Nitroxyl peptides as catalysts of enantioselective oxidations (458 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002; 8(1): [d]84-93.
Impact Factor: 4.238
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Monti SM, Ritieni A, Sacchi R, Skog K, Borgen E, Fogliano V
* Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system (470 visite)
J Agric Food Chem (ISSN: 0021-8561), 2001 Sep; 49(8): 3969-3975.
Impact Factor: 1.576
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Monti SM, Borrelli RC, Ritieni A, Fogliano V
A comparison of color formation and Maillard reaction products of a lactose-lysine and lactose-N(α)-acetyllysine model system (396 visite)
J Agric Food Chem (ISSN: 0021-8561), 2000; 48(4): 1041-1046.
Impact Factor: 1.56
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Monti SM, Ritieni A, Graziani G, Randazzo G, Mannina L, Segre AL, Fogliano V
LC/MS analysis and antioxidative efficiency of Maillard reaction products from a lactose-lysine model system (410 visite)
J Agric Food Chem (ISSN: 0021-8561), 1999 Apr; 47(4): 1506-1513.
Impact Factor: 1.453
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (358 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (307 visite)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
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Fogliano V, Monti SM, Musella T, Randazzo G, Ritieni A
Formation Of Colored Maillard Reaction Products In A Gluten-Glucose Model System (189 visite)
Journal Of Agricultural And Food Chemistry, 1999; 66: 293-299.
Impact Factor: 1.453
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Fogliano V, Monti SM, Visconti A, Randazzo G, Facchiano AM, Colonna G, Ritieni A
Identification of a β-lactoglobulin lactosylation site (302 visite)
Biochim Biophys Acta Protein Struct Mol Enzymol (ISSN: 0167-4838), 1998 Nov 10; 1388(2): 295-304.
Impact Factor: 1.687
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Pavone V, Lombardi A, Saviano M, Nastri F, Zaccaro L, Maglio O, Pedone C, Omote Y, Yamanaka Y, Yamada T
Conformational Behaviour Of C (alpha, Alpha)-Diphenylglycine: Folded Vs. Extended Structures In Dphig-Containing Tripeptides (421 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 1998 Feb; 4(1): 21-32.
Impact Factor: 1.311
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Postiglione A, Soricelli, Salvatore M, Lassen NA
123I-iomazenil as a clinical tool for studying neuronal loss [4] (318 visite)
J Am Geriatr Soc (ISSN: 0002-8614), 1997 Apr; 45(4): 534-536.
Impact Factor: 2.806
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Fogliano V, Monti SM, Ritieni A, Marchisano C, Peluso G, Randazzo G
An immunological approach to monitor protein lactosylation of heated food model systems (248 visite)
Food Chem (ISSN: 0308-8146, 0308-8146print), 1997; 58(1-2): 53-58.
Impact Factor: 0.812
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (308 visite)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Miles AM, Gibson MF, Kirshina M, Cook JC, Pacelli R, Wink D, Grisham MB
Effects of superoxide on nitric oxide-dependent n-nitrosation reactions (278 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 1995 Oct; 23(4): 379-390.
Impact Factor: 2.361
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Sijens PE, Knopp MV, Brunetti A, Wicklow K, Alfano B, Bachert P, Sanders JA, Stillman AE, Kett H, Sauter R
1H MR spectroscopy in patients with metastatic brain tumors: A multicenter study (334 visite)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1995 Jun; 33(6): 818-826.
Impact Factor: 3.012
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50 Records (48 escludendo Abstract e Conferenze).
Impact factor totale: 146.761 (140.348 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 159.149 (152.964 escludendo Abstract e Conferenze).
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Bui N, Troise AD, Nijsse B, Roviello GN, Fogliano V, Devos W
* Intestinimonas-like bacteria are important butyrate producers that 1 utilize Nε-fructosyllysine and lysine in formula-fed infants and adults (99 visite)
Journal Of Functional Foods, 2020 Apr; 70: 103974-103980.
Impact Factor: 3.701
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Marchiori MF, Riul TB, Oliveira Bortot L, Andrade P, Junqueira GG, Foca G, Doti N, Ruvo M, Dias-baruffi M, Carvalho I, Campo VL
* Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion (559 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391), 2017 Nov 1; 25(21): 6049-6059.
Impact Factor: 2.881
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Roviello GN, Iannitti R, Palumbo R, Simonyan H, Vicidomini C, Roviello V
* Lac-L-TTA, a novel lactose-based amino acid-sugar conjugate for anti-metastatic applications (276 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 May 06; 49(8): 1347-1353.
Impact Factor: 2.906
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Troise AD, Buonanno M, Fiore A, Monti SM, Fogliano V
* Evolution of protein bound Maillard reaction end-products and free Amadori compounds in low lactose milk in presence of fructosamine oxidase (302 visite)
Food Chem (ISSN: 0308-8146, 0308-8146print), 2016 Dec 1; 212: 722-729.
Impact Factor: 4.529
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (804 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Speciale I, Paciello I, Fazio LL, Sturiale L, Palmigiano A, Lanzetta R, Parrilli M, Garozzo D, Lemaitre B, Bernardini ML, Molinaro A, De Castro C
* Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties (309 visite)
Carbohyd Res (ISSN: 0008-6215), 2015; 412: 20-27.
Impact Factor: 1.817
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Bellia F, Vecchio G, Rizzarelli E
* Carnosinases, Their Substrates And Diseases (379 visite)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2014 Feb 21; 19(2): 2299-2329.
Impact Factor: 2.416
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Troise AD, Dathan NA, Fiore A, Roviello G, Di Fiore A, Caira S, Cuollo M, De Simone G, Fogliano V, Monti SM
* Faox enzymes inhibited Maillard reaction development during storage both in protein glucose model system and low lactose UHT milk (198 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014 Feb; 46(2): 279-288.
Impact Factor: 3.293
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Autiero I, Saviano M, Langella E
* In silico investigation and targeting of amyloid beta oligomers of different size (424 visite)
Mol Biosyst (ISSN: 1742-206x, 1742-2051electronic), 2013 Aug; 9(8): 2118-2124.
Impact Factor: 3.18
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Pennacchio A, Sannino V, Sorrentino G, Rossi M, Raia CA, Esposito L
* Biochemical and structural characterization of recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius highly enantioselective on diaryl diketone benzil (355 visite)
Appl Microbiol Biot (ISSN: 0175-7598), 2013 May; 97(9): 1-16.
Impact Factor: 3.811
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Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (313 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
Impact Factor: 4.794
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Gustavsson T, Sarkar S, Vaya I, Jimenez MC, Markovitsi D, Improta R
* A joint experimental/theoretical study of the ultrafast excited state deactivation of deoxyadenosine and 9-methyladenine in water and acetonitrile (273 visite)
Photochem Photobiol Sci (ISSN: 1474-905x), 2013; 12(8): 1375-1386.
Impact Factor: 2.939
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Improta R
* Photophysics and photochemistry of thymine deoxy-dinucleotide in water: A PCM/TD-DFT quantum mechanical study (272 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2012 Dec 13; 116(49): 14261-14274.
Impact Factor: 3.607
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Monfregola L, Leone M, Calce E, de Luca S
* Postsynthetic modification of peptides via chemoselective N-alkylation of their side chains (419 visite)
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2012 Apr 6; 14(7): 1664-1667.
Impact Factor: 6.142
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Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (338 visite)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (370 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Alterio V, Monti SM, Truppo E, Pedone C, Supuran CT, De Simone G
* The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: The carbonic anhydrase I-topiramate complex (371 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2010 Sep 7; 8(15): 3528-3533.
Impact Factor: 3.451
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (435 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Mancini M, Greco A, Speranza A, Salvatore M
* Ultrasound molecular imaging by targeted microbubble contrast agents (364 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Jun; 21(2): 97-110.
Impact Factor: 0.268
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Roviello GN, Musumeci D, Moccia M, Castiglione M, Cesarani A, Bucci EM, Saviano M, Pedone C, Benedetti E
* Evidences Of Complex Formation Between Daba-Based Nucleo-Gamma-Peptides With Alternate Configuration Backbone (400 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 147-154.
Impact Factor: 1.807
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Dudar GK, D'Andrea LD, Di Stasi R, Pedone C, Wallace JL
* A vascular endothelial growth factor mimetic accelerates gastric ulcer healing in an iNOS-dependent manner (658 visite)
Am J Physiol Gastrointest Liver Physiol American Journal Of Physiology Gastrointestinal And Liver Physiology (ISSN: 0193-1857), 2008 Sep; 295(2): G374-G381.
Impact Factor: 3.587
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Pulcrano M, Camera L, Pagano L, Del Vecchio S, Ferone D, Bodei L, Murgia A, Pace L, Storto G, Paganelli G, Colao A, Salvatore M, Lombardi G, Biondi B
* Usefulness of [(111)In-DTPA(0)] octreotide scintigraphy in a family with von Hippel-Lindau disease (334 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2008 Apr; 31(4): 352-359.
Impact Factor: 1.888
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D'Andrea LD, Testa I, Panico M, Di Stasi R, Carac C, Tarallo L, Arra C, Barbieri A, Romanelli A, Aloj L
* In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with Tc-99m-tricarbonyl (399 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 90(5): 707-712.
Impact Factor: 2.823
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Vergara A, Vitagliano L, Verde C, di Prisco G, Mazzarella L
* Spectroscopic and crystallographic characterization of bis-histidyl adducts in tetrameric hemoglobins (383 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 2008; 436: 425-444.
Impact Factor: 2.312
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (419 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
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D'Auria S, Varriale A, Gonnelli M, Saviano M, Staiano M, Rossi M, Strambini GB
* Tryptophan phosphorescence studies of the D-galactose/ D-glucose-binding protein from Escherichia coli provide a molecular portrait with structural and dynamics features of the protein (522 visite)
J Proteome Res (ISSN: 1535-3893), 2007; 6(4): 1306-1312.
Impact Factor: 5.675
Dettagli Esporta in BibTeX Esporta in EndNote
Pailot A, D'Ambrosio K, Corbier C, Talfournier F, Branlant G
* Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans (302 visite)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2006 Dec 15; 400: 521-530.
Impact Factor: 4.1
Dettagli Esporta in BibTeX Esporta in EndNote
De Luca S, Saviano M, Della Moglie R, Digilio G, Bracco C, Aloj L, Tarallo L, Pedone C, Morelli G
* Conformationally constrained CCK8 analogues obtained from a rationally designed peptide library as ligands for cholecystokinin type B receptor (386 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2006 Sep; 1(9): 997-1006.
Impact Factor: 3.046
Dettagli Esporta in BibTeX Esporta in EndNote
Nuernberger P, Vogt G, Gerber G, Improta R, Santoro F
* Femtosecond study on the isomerization dynamics of NK88. I. Ground-state dynamics after photoexcitation (330 visite)
J Chem Phys (ISSN: 0021-9606, 0021-9606print, 0897-690online), 2006 Jul 28; 125(4): 44512-44544.
Impact Factor: 3.247
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Vogt G, Nuernberger P, Gerber G, Improta R, Santoro F, Nuernberger P, Vogt G, Gerber G, Improta R, Santoro F
* Femtosecond study on the isomerization dynamics of NK88. II. Excited-state dynamics (312 visite)
J Chem Phys (ISSN: 0021-9606, 0897-690online), 2006 Jul 28; 125(4): 44512-44512.
Impact Factor: 3.166
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D'Agata R, Grasso G, Iacono G, Spoto G, Vecchio G
* Lectin recognition of a new SOD mimic bioconjugate studied with surface plasmon resonance imaging (273 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2006 Feb 21; 4(4): 610-612.
Impact Factor: 2.874
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Saviano M, Improta R, Benedetti E, Carrozzini B, Cascarano GL, Didierjean C, Toniolo C, Crisma M
* Benzophenone photophore flexibility and proximity: Molecular and crystal-state structure of a Bpa-containing trichogin dodecapeptide analogue (365 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Apr 2; 5(4): 541-544.
Impact Factor: 3.474
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Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
* In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (541 visite)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2004 Mar; 45(3): 485-494.
Impact Factor: 5.362
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (262 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Camera L, Del Vecchio S, Quarantelli M, Ibello F, Pellegrino T, Salvatore M
* Radiolabeled somatostatin analogs in the diagnosis and staging of neuroendocrine tumors (312 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2003; 26(8Suppl): 60-62.
Impact Factor: 1.621
Dettagli Esporta in BibTeX Esporta in EndNote
Vitaglione P, Monti SM, Ambrosino P, Skog K, Fogliano V
* Carotenoids from tomatoes inhibit heterocyclic amine formation (192 visite)
Eur Food Res Technol (ISSN: 1438-2377), 2002 Sep; 215(2): 108-113.
Impact Factor: 1.021
Dettagli Esporta in BibTeX Esporta in EndNote
Formaggio F, Bonchio M, Crisma M, Peggion C, Mezzato S, Polese A, Barazza A, Antonello S, Maran F, Broxterman QB, Kaptein B, Kamphuis J, Vitale RM, Saviano M, Benedetti E, Toniolo C
* Nitroxyl peptides as catalysts of enantioselective oxidations (458 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002; 8(1): [d]84-93.
Impact Factor: 4.238
Dettagli Esporta in BibTeX Esporta in EndNote
Monti SM, Ritieni A, Sacchi R, Skog K, Borgen E, Fogliano V
* Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system (470 visite)
J Agric Food Chem (ISSN: 0021-8561), 2001 Sep; 49(8): 3969-3975.
Impact Factor: 1.576
Dettagli Esporta in BibTeX Esporta in EndNote
Monti SM, Borrelli RC, Ritieni A, Fogliano V
A comparison of color formation and Maillard reaction products of a lactose-lysine and lactose-N(α)-acetyllysine model system (396 visite)
J Agric Food Chem (ISSN: 0021-8561), 2000; 48(4): 1041-1046.
Impact Factor: 1.56
Dettagli Esporta in BibTeX Esporta in EndNote
Monti SM, Ritieni A, Graziani G, Randazzo G, Mannina L, Segre AL, Fogliano V
LC/MS analysis and antioxidative efficiency of Maillard reaction products from a lactose-lysine model system (410 visite)
J Agric Food Chem (ISSN: 0021-8561), 1999 Apr; 47(4): 1506-1513.
Impact Factor: 1.453
Dettagli Esporta in BibTeX Esporta in EndNote
Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (358 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
Dettagli Esporta in BibTeX Esporta in EndNote
Fonti R, Cheung N-KV, Bridger GJ, Guo H-F, Abrams MJ, Larson SM
99mTc-monoclonal antibody radiolabeled via hydrazino nicotinamide derivative for imaging disialoganglioside G(D2)-positive tumors (307 visite)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1999; 26(6): 681-686.
Impact Factor: 1.623
Dettagli Esporta in BibTeX Esporta in EndNote
Fogliano V, Monti SM, Musella T, Randazzo G, Ritieni A
Formation Of Colored Maillard Reaction Products In A Gluten-Glucose Model System (189 visite)
Journal Of Agricultural And Food Chemistry, 1999; 66: 293-299.
Impact Factor: 1.453
Dettagli Esporta in BibTeX Esporta in EndNote
Fogliano V, Monti SM, Visconti A, Randazzo G, Facchiano AM, Colonna G, Ritieni A
Identification of a β-lactoglobulin lactosylation site (302 visite)
Biochim Biophys Acta Protein Struct Mol Enzymol (ISSN: 0167-4838), 1998 Nov 10; 1388(2): 295-304.
Impact Factor: 1.687
Dettagli Esporta in BibTeX Esporta in EndNote
Pavone V, Lombardi A, Saviano M, Nastri F, Zaccaro L, Maglio O, Pedone C, Omote Y, Yamanaka Y, Yamada T
Conformational Behaviour Of C (alpha, Alpha)-Diphenylglycine: Folded Vs. Extended Structures In Dphig-Containing Tripeptides (421 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 1998 Feb; 4(1): 21-32.
Impact Factor: 1.311
Dettagli Esporta in BibTeX Esporta in EndNote
Postiglione A, Soricelli, Salvatore M, Lassen NA
123I-iomazenil as a clinical tool for studying neuronal loss [4] (318 visite)
J Am Geriatr Soc (ISSN: 0002-8614), 1997 Apr; 45(4): 534-536.
Impact Factor: 2.806
Dettagli Esporta in BibTeX Esporta in EndNote
Fogliano V, Monti SM, Ritieni A, Marchisano C, Peluso G, Randazzo G
An immunological approach to monitor protein lactosylation of heated food model systems (248 visite)
Food Chem (ISSN: 0308-8146, 0308-8146print), 1997; 58(1-2): 53-58.
Impact Factor: 0.812
Dettagli Esporta in BibTeX Esporta in EndNote
Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (308 visite)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
Dettagli Esporta in BibTeX Esporta in EndNote
Miles AM, Gibson MF, Kirshina M, Cook JC, Pacelli R, Wink D, Grisham MB
Effects of superoxide on nitric oxide-dependent n-nitrosation reactions (278 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 1995 Oct; 23(4): 379-390.
Impact Factor: 2.361
Dettagli Esporta in BibTeX Esporta in EndNote
Sijens PE, Knopp MV, Brunetti A, Wicklow K, Alfano B, Bachert P, Sanders JA, Stillman AE, Kett H, Sauter R
1H MR spectroscopy in patients with metastatic brain tumors: A multicenter study (334 visite)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1995 Jun; 33(6): 818-826.
Impact Factor: 3.012
Dettagli Esporta in BibTeX Esporta in EndNote
50 Records (48 escludendo Abstract e Conferenze).
Impact factor totale: 146.761 (140.348 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 159.149 (152.964 escludendo Abstract e Conferenze).
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