Extraction of azadirachtin a from neem seed kernels by supercritical fluid and its evaluation by HPLC and LC/MS (869 views)
J Agric Food Chem (ISSN: 0021-8561), 1999 Dec; 47(12): 5252-5256.
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Paper type: Journal Article,
Impact factor: 1.453, 5-year impact factor: 3.172
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033381442&partnerID=40&md5=0dd487820ee7057507671506e5f1fa4d
Keywords: Azadirachtin A, Hplc, Lc Ms, Neem Seed Kernels, Supercritical Fluid Extraction, Carbon Dioxide, Insecticide, Triterpene, Animal, Article, Calculation, Chemical Structure, Chemistry, Controlled Study, High Performance Liquid Chromatography, Isolation And Purification, Mass Fragmentography, Mass Spectrometry, Nonhuman, Plant Seed, High Pressure Liquid, Gas Chromatography-Mass Spectrometry, Limonins, Trees, Azadirachta Indica,
Affiliations:
Dipto. di Scienza degli Alimenti, Universita Napoli Federico II P., 80055 Portici (Napoli), Italy
Dipartimento di Ingegneria Chimica, Università di Salerno, via Ponte Don Melillo, 84084 Fisciano (Salerno), Italy
References:
Not available.
J Agric Food Chem (ISSN: 0021-8561), 1999 Dec; 47(12): 5252-5256.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.453, 5-year impact factor: 3.172
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0033381442&partnerID=40&md5=0dd487820ee7057507671506e5f1fa4d
Keywords: Azadirachtin A, Hplc, Lc Ms, Neem Seed Kernels, Supercritical Fluid Extraction, Carbon Dioxide, Insecticide, Triterpene, Animal, Article, Calculation, Chemical Structure, Chemistry, Controlled Study, High Performance Liquid Chromatography, Isolation And Purification, Mass Fragmentography, Mass Spectrometry, Nonhuman, Plant Seed, High Pressure Liquid, Gas Chromatography-Mass Spectrometry, Limonins, Trees, Azadirachta Indica,
Affiliations:
Dipto. di Scienza degli Alimenti, Universita Napoli Federico II P., 80055 Portici (Napoli), Italy
Dipartimento di Ingegneria Chimica, Università di Salerno, via Ponte Don Melillo, 84084 Fisciano (Salerno), Italy
References:
Not available.
Extraction of azadirachtin a from neem seed kernels by supercritical fluid and its evaluation by HPLC and LC/MS
A new supercritical extraction methodology was applied to extract azadirachtin A (AZA-A) from neem seed kernels. Supercritical and liquid carbon dioxide (CO2) were used as extractive agents in a three-separation- stage supercritical pilot plant. Subcritical conditions were tested too. Comparisons were carried out by calculating the efficiency of the pilot plant with respect to the milligrams per kilogram of seeds (ms/mo) of AZA-A extracted. The most convenient extraction was gained using an ms/mo ratio of 119 rather than 64. For supercritical extraction, a separation of cuticular waxes from oil was set up in the pilot plant. HPLC and electrospray mass spectroscopy were used to monitor the yield of AZA-A extraction.
A new supercritical extraction methodology was applied to extract azadirachtin A (AZA-A) from neem seed kernels. Supercritical and liquid carbon dioxide (CO2) were used as extractive agents in a three-separation- stage supercritical pilot plant. Subcritical conditions were tested too. Comparisons were carried out by calculating the efficiency of the pilot plant with respect to the milligrams per kilogram of seeds (ms/mo) of AZA-A extracted. The most convenient extraction was gained using an ms/mo ratio of 119 rather than 64. For supercritical extraction, a separation of cuticular waxes from oil was set up in the pilot plant. HPLC and electrospray mass spectroscopy were used to monitor the yield of AZA-A extraction.
Extraction of azadirachtin a from neem seed kernels by supercritical fluid and its evaluation by HPLC and LC/MS
| ▼ Carbonic Anhydrase IX as target for the development of new anti-tumour drugs |
Extraction of azadirachtin a from neem seed kernels by supercritical fluid and its evaluation by HPLC and LC/MS
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13 Records (13 excluding Abstracts).
Total impact factor: 100.16 (100.16 excluding Abstracts).
Total 5 year impact factor: 102.806 (102.806 excluding Abstracts).
Total impact factor: 100.16 (100.16 excluding Abstracts).
Total 5 year impact factor: 102.806 (102.806 excluding Abstracts).
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