Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide (600 views)
Soft Matter (ISSN: 1744-683x), 2013; 9(18): 4648-4654.
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Paper type: Journal Article,
Impact factor: 4.151, 5-year impact factor: 4.429
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84879544819&partnerID=40&md5=ae7a0e0b2dacdfae10ddf59a1a6c48d1
Keywords: Core-Shell Nanoparticles, Electrostatically Driven, Energy Transfer Process, Hydrophilic Substrate, Multi-Technique Approach, Nerve Growth Factor, Peptide Association, Supported Lipid Bilayers, Association Reactions, Drug Delivery, Fluorescence Spectroscopy, Silica,
Affiliations:
*** IBB - CNR ***
Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6, 95125 Catania, Italy
Institute of Biostructures and Bioimages, Catania National Council of Research (CNR), viale Andrea Doria, 6, 95125 Catania, Italy
Department of Pharmacy, University of Pisa, via Bonanno Pisano 6, 56100 Pisa, Italy
G. Ciamician Department of Chemistry, University of Bologna, Via Selmi 2, 40126 Bologna, Italy
References:
Not available.
Soft Matter (ISSN: 1744-683x), 2013; 9(18): 4648-4654.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 4.151, 5-year impact factor: 4.429
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84879544819&partnerID=40&md5=ae7a0e0b2dacdfae10ddf59a1a6c48d1
Keywords: Core-Shell Nanoparticles, Electrostatically Driven, Energy Transfer Process, Hydrophilic Substrate, Multi-Technique Approach, Nerve Growth Factor, Peptide Association, Supported Lipid Bilayers, Association Reactions, Drug Delivery, Fluorescence Spectroscopy, Silica,
Affiliations:
*** IBB - CNR ***
Department of Chemical Sciences, University of Catania, viale Andrea Doria, 6, 95125 Catania, Italy
Institute of Biostructures and Bioimages, Catania National Council of Research (CNR), viale Andrea Doria, 6, 95125 Catania, Italy
Department of Pharmacy, University of Pisa, via Bonanno Pisano 6, 56100 Pisa, Italy
G. Ciamician Department of Chemistry, University of Bologna, Via Selmi 2, 40126 Bologna, Italy
References:
Not available.
Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide
The interaction between lipid vesicles and NGF(1-14) peptide, mimicking nerve growth factor, was addressed to fabricate peptide-associated supported lipid bilayers (SLBs). According to a model of predominant electrostatic interactions, zwitterionic and anionic lipid vesicles were used to optimize the peptide association with the lipid membranes. Both planar silica and core-shell nanoparticles (NPs) were used as polar hydrophilic substrates to form the SLBs functionalized with the NGF peptide. The hybrid biointerface was scrutinized by a multitechnique approach with QCM-D, FRAP and fluorescence spectroscopy in terms of self-assembling kinetics, lipid lateral diffusion, and energy transfer processes in the SLB-wrapped silica NPs dye-doped in the core. The response of neuronal cells to the NGF(1-14)-SLBs highlighted their promising application as a drug delivery nanoplatform for ageing-related diseases. This journal is © 2013 The Royal Society of Chemistry.
The interaction between lipid vesicles and NGF(1-14) peptide, mimicking nerve growth factor, was addressed to fabricate peptide-associated supported lipid bilayers (SLBs). According to a model of predominant electrostatic interactions, zwitterionic and anionic lipid vesicles were used to optimize the peptide association with the lipid membranes. Both planar silica and core-shell nanoparticles (NPs) were used as polar hydrophilic substrates to form the SLBs functionalized with the NGF peptide. The hybrid biointerface was scrutinized by a multitechnique approach with QCM-D, FRAP and fluorescence spectroscopy in terms of self-assembling kinetics, lipid lateral diffusion, and energy transfer processes in the SLB-wrapped silica NPs dye-doped in the core. The response of neuronal cells to the NGF(1-14)-SLBs highlighted their promising application as a drug delivery nanoplatform for ageing-related diseases. This journal is © 2013 The Royal Society of Chemistry.
Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide
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Electrostatically driven interaction of silica-supported lipid bilayer nanoplatforms and a nerve growth factor-mimicking peptide
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Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
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Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A
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* A versatile strategy for signal amplification based on core/shell silica nanoparticles (1085 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Nov 25; 17(48): 13429-13432.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A
* MR Contrast Agents (587 views)
Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555.
Impact Factor: 1.784
View Export to BibTeX Export to EndNote
Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (1010 views)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
View Export to BibTeX Export to EndNote
3 Records (3 excluding Abstracts).
Total impact factor: 10.777 (10.777 excluding Abstracts).
Total 5 year impact factor: 11.012 (11.012 excluding Abstracts).
Total impact factor: 10.777 (10.777 excluding Abstracts).
Total 5 year impact factor: 11.012 (11.012 excluding Abstracts).
600 views. Last view on Sunday 18 May 2025, 19:40:43
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