ESR study of the non-enzymic scission of xyloglucan by an ascorbate-H2O2-copper system: The involvement of the hydroxyl radical and the degradation of ascorbate (312 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2001 Apr; 84(3-4): 179-187.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.729, 5-year impact factor: 3.452
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035317379&partnerID=40&md5=2a1561a10a17fa2216b6d9546c95efb4
Keywords: Ascorbate, Copper, Hydrogen Peroxide, Hydroxyl Radical, Scission, Spin Trapping, Xyloglucan, Ascorbic Acid, Polysaccharide, Article, Chemistry, Electron Spin Resonance, Metabolism, Electron Spin Resonance Spectroscopy, Xylans,
Affiliations:
Istituto per lo Studio delle Sostanze Naturali di Interesse Alimentare e Chimico-Farmaceutico, CNR, Sezione per lo Studio dei Metalloenzimi, Viale A. Doria 6, 95125 Catania, Italy
Edinburgh Cell Wall Group, Institute of Cell and Molecular Biology, University of Edinburgh, Edinburgh EH9 3JH, United Kingdom
Dipartimento di Scienze Chimiche, Università di Catania, Viale A. Doria 6, 95125 Catania, Italy
References:
Fry, S.C., (1995) Annu. Rev. Plant Physiol. Plant Mol. Biol., 46, pp. 497-52
Skanse, B., Sundblad, L., (1943) Acta Physiol. Scand., 6, pp. 37-50
Miller, A.R., (1986) Biochem. Biophys. Res. Commun., 141, p. 238244
Halliwell, B., Gutteridge, J.M.C., (1990) Method in Enzymology, 186, pp. 1-85. , L. Packer, A.N. Glazer (Eds.), Academic Press, San Diego
Scott, J.E., Tigwell, M.J., (1973) Carbohydr. Res., 28, pp. 53-59
Mitchel, R.E.J., (1976) Radiat. Res., 66, pp. 158-169
Elstner, E.F., (1987) The Biochemistry of Plants: A Comprehensive Treatise, Biochemistry of Metabolism, 11, pp. 203-315. , D.D. Davies (Ed.), Academic Press, San Diego
Fry, S.C., (1998) Biochem. J., 332, pp. 507-515
Duling, D.R., (1994) J. Magn. Res. B, 104, pp. 105-110
Pilbrow, J.R., Winfield, M.E., (1973) Mol. Phys., 25, pp. 1073-1092
Fréjaville, C., Karoui, H., Tuccio, B., Le Moigne, F., Culcasi, M., Pietri, S., Lauricella, R., Tordo, P., (1995) J. Med. Chem., 38, pp. 258-265
Vâsquez-Vivar, J., Hogg, N., Pritchard, K.A., Martasek, P., Kalyanaraman, B., (1997) FEBS Lett., 403, pp. 127-130
Karoui, H., Hogg, N., Fréjaville, C., Tordo, P., Kalyanaraman, B., (1996) J. Biol. Chem., 271, pp. 6000-6009
Roubaud, V., Mercier, A., Olive, G., Le Moigne, F., Tordo, P., (1997) J. Chem. Soc., Perkin Trans. 2, pp. 1827-1830
Roubaud, V., Sankarapandi, S., Kuppusamy, P., Tordo, P., Zweier, J.L., (1997) Anal. Biochem., 247, pp. 404-411
Haseloff, R.F., Ebert, B., Wischnewsky, G.G., (1991) Anal. Chim. Acta, 243, pp. 221-225
Turner, M.J., Rosen, G.M., (1986) J. Med. Chem., 29, pp. 2439-2444
Finkelstein, E., Rosen, G.M., Rauckman, E.J., (1980) J. Am. Chem. Soc., 102, pp. 4994-4999
Pou, S., Ramos, C.L., Gladwell, T., Renks, E., Centra, M., Young, D., Cohen, M.C., Rosen, G.M., (1994) Anal. Biochem., 217, pp. 76-83
Buettner, G.R., Oberley, L.W., (1978) Biochem. Biophys. Res. Commun., 83, pp. 69-74
Mitsuta, K., Hiramatsu, M., Ohya-Nishiguchi, H., Kamada, H., Fujii, K., (1994) Bull. Chem. Soc. Jpn., 67, pp. 529-538
Ueda, J., Ozawa, T., Miyazaki, M., Fujiwara, Y., (1994) J. Inorg. Biochem., 55, pp. 123-130
Aruoma, O.I., Halliwell, B., Gajewski, E., Dizdaroglu, M., (1991) Biochem. J., 273, pp. 601-604
Bernofsky, C., Bandara, B.M., (1995) Mol. Cell. Biochem., 148, pp. 155-164
Lohmann, W., Holz, D., (1984) Biophys. Struct. Mech., 10, pp. 197-204
Simic, M.G., (1990) Method in Enzymology, 186, pp. 89-100. , L. Packer, A.N. Glazer (Eds.), Academic Press, San Diego
Timmins, G.S., Liu, K.J., Bechara, E.J.H., Kotake, Y., Swartz, H.M., (1999) Free Radic. Biol. Med., 27, pp. 329-333
Bonomo, R.P., Marchelli, R., Tabbì, G., (1995) J. Inorg. Biochem., 60, pp. 205-218
Sigel, H., Flierl, C., Griesser, R., (1969) J. Am. Chem. Soc., 91, pp. 1061-1064
Luo, Y., Kustin, K., Epstein, I.R., (1988) Inorg. Chem., 27, pp. 2489-2496
Ozawa, T., Hanaki, A., (1992) Polyhedron, 11, pp. 735-738
Amico, P., Bonomo, R.P., Cali, R., Cucinotta, V., Daniele, P.G., Ostacoli, G., Rizzarelli, E., (1989) Inorg. Chem., 28, pp. 3555-3561
Mi, L., Zuberbühler, A.D., (1992) Helv. Chim. Acta, 75, pp. 1547-1556
Saito, K., Ohmoto, J., Kunha, N., (1997) Phytochemistry, 44, pp. 805-809
Buxton, G.V., Greenstock, C.L., Helman, W.P., Ross, A.B., (1988) J. Phys. Chem. Ref. Data, 17, pp. 513-886
Motohashi, N., Saito, Y., (1993) Chem. Pharm. Bull., 41, pp. 1842-1845
Baker, M.Z., Badiello, R., Tamba, M., Quintiliani, M., Gorin, G., (1982) Int. J. Radiat. Biol., 41, pp. 595-602
Goldstein, S., Meyerstein, D., Czapski, G., (1993) Free Radic. Biol. Med, 15, pp. 435-445
Meyerstein, D., (1971) Inorg. Chem., 10, pp. 638-641
Eberhardt, M.K., Ramirez, G., Ayala, E., (1989) J. Org. Chem., 54, pp. 5922-5926
Marsarwa, M., Cohen, H., Meyerstein, D., Hichman, D.L., Bakac, A., Espenson, J.H., (1988) J. Am. Chem. Soc., 110, pp. 4293-4297
Johnson, G.R.A., Nazhat, N.B., (1987) J. Am. Chem. Soc., 109, pp. 1990-1994
Bjergbakke, E., Sehested, K., Rasmussen, O.L., (1976) Radiat. Res., 66, pp. 433-442
Von Piechowski, M., Nauser, T., Hoigne, J., Buehler, R.E., (1993) Ber. Bunsenges. Phys. Chem., 97, pp. 762-771
Goldstein, S., Michel, C., Bors, W., Saran, M., Czapski, G., (1988) Free Radic. Biol. Med., 4, pp. 295-303
Cabelli, D.E., Bielski, B.H.J., Holcman, J., (1987) J. Am. Chem. Soc., 109, pp. 3665-3669
Goldstein, S., Czapski, G., (1985) Inorg. Chem., 24, pp. 1087-1092
Ettinger, K.V., Forrester, A.R., Hunter, C.H., (1982) Can. J. Chem., 60, pp. 1549-1559
Thornalley, P.J., Stern, A., (1984) Carbohydr. Res., 134, pp. 191-204
Schuchmann, M.N., Von Sonntag, C., (1978) Int. J. Radiat. Biol., 34, pp. 397-400
Deeble, D.J., Bothe, E., Schuchmann, H.P., Parsons, B.J., Phillips, G.O., Von Sonntag, C., (1990) Z. Naturforsch. C, 45, pp. 1031-1043
Fry, S. C., (1995) Annu. Rev. Plant Physiol. Plant Mol. Biol., 46, pp. 497-52
Miller, A. R., (1986) Biochem. Biophys. Res. Commun., 141, p. 238244
Scott, J. E., Tigwell, M. J., (1973) Carbohydr. Res., 28, pp. 53-59
Mitchel, R. E. J., (1976) Radiat. Res., 66, pp. 158-169
Elstner, E. F., (1987) The Biochemistry of Plants: A Comprehensive Treatise, Biochemistry of Metabolism, 11, pp. 203-315. , D. D. Davies (Ed.), Academic Press, San Diego
Fry, S. C., (1998) Biochem. J., 332, pp. 507-515
Duling, D. R., (1994) J. Magn. Res. B, 104, pp. 105-110
Pilbrow, J. R., Winfield, M. E., (1973) Mol. Phys., 25, pp. 1073-1092
Fr javille, C., Karoui, H., Tuccio, B., Le Moigne, F., Culcasi, M., Pietri, S., Lauricella, R., Tordo, P., (1995) J. Med. Chem., 38, pp. 258-265
V squez-Vivar, J., Hogg, N., Pritchard, K. A., Martasek, P., Kalyanaraman, B., (1997) FEBS Lett., 403, pp. 127-130
Haseloff, R. F., Ebert, B., Wischnewsky, G. G., (1991) Anal. Chim. Acta, 243, pp. 221-225
Turner, M. J., Rosen, G. M., (1986) J. Med. Chem., 29, pp. 2439-2444
Pou, S., Ramos, C. L., Gladwell, T., Renks, E., Centra, M., Young, D., Cohen, M. C., Rosen, G. M., (1994) Anal. Biochem., 217, pp. 76-83
Buettner, G. R., Oberley, L. W., (1978) Biochem. Biophys. Res. Commun., 83, pp. 69-74
Aruoma, O. I., Halliwell, B., Gajewski, E., Dizdaroglu, M., (1991) Biochem. J., 273, pp. 601-604
Simic, M. G., (1990) Method in Enzymology, 186, pp. 89-100. , L. Packer, A. N. Glazer (Eds.), Academic Press, San Diego
Timmins, G. S., Liu, K. J., Bechara, E. J. H., Kotake, Y., Swartz, H. M., (1999) Free Radic. Biol. Med., 27, pp. 329-333
Bonomo, R. P., Marchelli, R., Tabb, G., (1995) J. Inorg. Biochem., 60, pp. 205-218
Mi, L., Zuberb hler, A. D., (1992) Helv. Chim. Acta, 75, pp. 1547-1556
Buxton, G. V., Greenstock, C. L., Helman, W. P., Ross, A. B., (1988) J. Phys. Chem. Ref. Data, 17, pp. 513-886
Baker, M. Z., Badiello, R., Tamba, M., Quintiliani, M., Gorin, G., (1982) Int. J. Radiat. Biol., 41, pp. 595-602
Eberhardt, M. K., Ramirez, G., Ayala, E., (1989) J. Org. Chem., 54, pp. 5922-5926
Johnson, G. R. A., Nazhat, N. B., (1987) J. Am. Chem. Soc., 109, pp. 1990-1994
Cabelli, D. E., Bielski, B. H. J., Holcman, J., (1987) J. Am. Chem. Soc., 109, pp. 3665-3669
Ettinger, K. V., Forrester, A. R., Hunter, C. H., (1982) Can. J. Chem., 60, pp. 1549-1559
Thornalley, P. J., Stern, A., (1984) Carbohydr. Res., 134, pp. 191-204
Schuchmann, M. N., Von Sonntag, C., (1978) Int. J. Radiat. Biol., 34, pp. 397-400
Deeble, D. J., Bothe, E., Schuchmann, H. P., Parsons, B. J., Phillips, G. O., Von Sonntag, C., (1990) Z. Naturforsch. C, 45, pp. 1031-1043
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2001 Apr; 84(3-4): 179-187.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.729, 5-year impact factor: 3.452
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035317379&partnerID=40&md5=2a1561a10a17fa2216b6d9546c95efb4
Keywords: Ascorbate, Copper, Hydrogen Peroxide, Hydroxyl Radical, Scission, Spin Trapping, Xyloglucan, Ascorbic Acid, Polysaccharide, Article, Chemistry, Electron Spin Resonance, Metabolism, Electron Spin Resonance Spectroscopy, Xylans,
Affiliations:
Istituto per lo Studio delle Sostanze Naturali di Interesse Alimentare e Chimico-Farmaceutico, CNR, Sezione per lo Studio dei Metalloenzimi, Viale A. Doria 6, 95125 Catania, Italy
Edinburgh Cell Wall Group, Institute of Cell and Molecular Biology, University of Edinburgh, Edinburgh EH9 3JH, United Kingdom
Dipartimento di Scienze Chimiche, Università di Catania, Viale A. Doria 6, 95125 Catania, Italy
References:
Fry, S.C., (1995) Annu. Rev. Plant Physiol. Plant Mol. Biol., 46, pp. 497-52
Skanse, B., Sundblad, L., (1943) Acta Physiol. Scand., 6, pp. 37-50
Miller, A.R., (1986) Biochem. Biophys. Res. Commun., 141, p. 238244
Halliwell, B., Gutteridge, J.M.C., (1990) Method in Enzymology, 186, pp. 1-85. , L. Packer, A.N. Glazer (Eds.), Academic Press, San Diego
Scott, J.E., Tigwell, M.J., (1973) Carbohydr. Res., 28, pp. 53-59
Mitchel, R.E.J., (1976) Radiat. Res., 66, pp. 158-169
Elstner, E.F., (1987) The Biochemistry of Plants: A Comprehensive Treatise, Biochemistry of Metabolism, 11, pp. 203-315. , D.D. Davies (Ed.), Academic Press, San Diego
Fry, S.C., (1998) Biochem. J., 332, pp. 507-515
Duling, D.R., (1994) J. Magn. Res. B, 104, pp. 105-110
Pilbrow, J.R., Winfield, M.E., (1973) Mol. Phys., 25, pp. 1073-1092
Fréjaville, C., Karoui, H., Tuccio, B., Le Moigne, F., Culcasi, M., Pietri, S., Lauricella, R., Tordo, P., (1995) J. Med. Chem., 38, pp. 258-265
Vâsquez-Vivar, J., Hogg, N., Pritchard, K.A., Martasek, P., Kalyanaraman, B., (1997) FEBS Lett., 403, pp. 127-130
Karoui, H., Hogg, N., Fréjaville, C., Tordo, P., Kalyanaraman, B., (1996) J. Biol. Chem., 271, pp. 6000-6009
Roubaud, V., Mercier, A., Olive, G., Le Moigne, F., Tordo, P., (1997) J. Chem. Soc., Perkin Trans. 2, pp. 1827-1830
Roubaud, V., Sankarapandi, S., Kuppusamy, P., Tordo, P., Zweier, J.L., (1997) Anal. Biochem., 247, pp. 404-411
Haseloff, R.F., Ebert, B., Wischnewsky, G.G., (1991) Anal. Chim. Acta, 243, pp. 221-225
Turner, M.J., Rosen, G.M., (1986) J. Med. Chem., 29, pp. 2439-2444
Finkelstein, E., Rosen, G.M., Rauckman, E.J., (1980) J. Am. Chem. Soc., 102, pp. 4994-4999
Pou, S., Ramos, C.L., Gladwell, T., Renks, E., Centra, M., Young, D., Cohen, M.C., Rosen, G.M., (1994) Anal. Biochem., 217, pp. 76-83
Buettner, G.R., Oberley, L.W., (1978) Biochem. Biophys. Res. Commun., 83, pp. 69-74
Mitsuta, K., Hiramatsu, M., Ohya-Nishiguchi, H., Kamada, H., Fujii, K., (1994) Bull. Chem. Soc. Jpn., 67, pp. 529-538
Ueda, J., Ozawa, T., Miyazaki, M., Fujiwara, Y., (1994) J. Inorg. Biochem., 55, pp. 123-130
Aruoma, O.I., Halliwell, B., Gajewski, E., Dizdaroglu, M., (1991) Biochem. J., 273, pp. 601-604
Bernofsky, C., Bandara, B.M., (1995) Mol. Cell. Biochem., 148, pp. 155-164
Lohmann, W., Holz, D., (1984) Biophys. Struct. Mech., 10, pp. 197-204
Simic, M.G., (1990) Method in Enzymology, 186, pp. 89-100. , L. Packer, A.N. Glazer (Eds.), Academic Press, San Diego
Timmins, G.S., Liu, K.J., Bechara, E.J.H., Kotake, Y., Swartz, H.M., (1999) Free Radic. Biol. Med., 27, pp. 329-333
Bonomo, R.P., Marchelli, R., Tabbì, G., (1995) J. Inorg. Biochem., 60, pp. 205-218
Sigel, H., Flierl, C., Griesser, R., (1969) J. Am. Chem. Soc., 91, pp. 1061-1064
Luo, Y., Kustin, K., Epstein, I.R., (1988) Inorg. Chem., 27, pp. 2489-2496
Ozawa, T., Hanaki, A., (1992) Polyhedron, 11, pp. 735-738
Amico, P., Bonomo, R.P., Cali, R., Cucinotta, V., Daniele, P.G., Ostacoli, G., Rizzarelli, E., (1989) Inorg. Chem., 28, pp. 3555-3561
Mi, L., Zuberbühler, A.D., (1992) Helv. Chim. Acta, 75, pp. 1547-1556
Saito, K., Ohmoto, J., Kunha, N., (1997) Phytochemistry, 44, pp. 805-809
Buxton, G.V., Greenstock, C.L., Helman, W.P., Ross, A.B., (1988) J. Phys. Chem. Ref. Data, 17, pp. 513-886
Motohashi, N., Saito, Y., (1993) Chem. Pharm. Bull., 41, pp. 1842-1845
Baker, M.Z., Badiello, R., Tamba, M., Quintiliani, M., Gorin, G., (1982) Int. J. Radiat. Biol., 41, pp. 595-602
Goldstein, S., Meyerstein, D., Czapski, G., (1993) Free Radic. Biol. Med, 15, pp. 435-445
Meyerstein, D., (1971) Inorg. Chem., 10, pp. 638-641
Eberhardt, M.K., Ramirez, G., Ayala, E., (1989) J. Org. Chem., 54, pp. 5922-5926
Marsarwa, M., Cohen, H., Meyerstein, D., Hichman, D.L., Bakac, A., Espenson, J.H., (1988) J. Am. Chem. Soc., 110, pp. 4293-4297
Johnson, G.R.A., Nazhat, N.B., (1987) J. Am. Chem. Soc., 109, pp. 1990-1994
Bjergbakke, E., Sehested, K., Rasmussen, O.L., (1976) Radiat. Res., 66, pp. 433-442
Von Piechowski, M., Nauser, T., Hoigne, J., Buehler, R.E., (1993) Ber. Bunsenges. Phys. Chem., 97, pp. 762-771
Goldstein, S., Michel, C., Bors, W., Saran, M., Czapski, G., (1988) Free Radic. Biol. Med., 4, pp. 295-303
Cabelli, D.E., Bielski, B.H.J., Holcman, J., (1987) J. Am. Chem. Soc., 109, pp. 3665-3669
Goldstein, S., Czapski, G., (1985) Inorg. Chem., 24, pp. 1087-1092
Ettinger, K.V., Forrester, A.R., Hunter, C.H., (1982) Can. J. Chem., 60, pp. 1549-1559
Thornalley, P.J., Stern, A., (1984) Carbohydr. Res., 134, pp. 191-204
Schuchmann, M.N., Von Sonntag, C., (1978) Int. J. Radiat. Biol., 34, pp. 397-400
Deeble, D.J., Bothe, E., Schuchmann, H.P., Parsons, B.J., Phillips, G.O., Von Sonntag, C., (1990) Z. Naturforsch. C, 45, pp. 1031-1043
Fry, S. C., (1995) Annu. Rev. Plant Physiol. Plant Mol. Biol., 46, pp. 497-52
Miller, A. R., (1986) Biochem. Biophys. Res. Commun., 141, p. 238244
Scott, J. E., Tigwell, M. J., (1973) Carbohydr. Res., 28, pp. 53-59
Mitchel, R. E. J., (1976) Radiat. Res., 66, pp. 158-169
Elstner, E. F., (1987) The Biochemistry of Plants: A Comprehensive Treatise, Biochemistry of Metabolism, 11, pp. 203-315. , D. D. Davies (Ed.), Academic Press, San Diego
Fry, S. C., (1998) Biochem. J., 332, pp. 507-515
Duling, D. R., (1994) J. Magn. Res. B, 104, pp. 105-110
Pilbrow, J. R., Winfield, M. E., (1973) Mol. Phys., 25, pp. 1073-1092
Fr javille, C., Karoui, H., Tuccio, B., Le Moigne, F., Culcasi, M., Pietri, S., Lauricella, R., Tordo, P., (1995) J. Med. Chem., 38, pp. 258-265
V squez-Vivar, J., Hogg, N., Pritchard, K. A., Martasek, P., Kalyanaraman, B., (1997) FEBS Lett., 403, pp. 127-130
Haseloff, R. F., Ebert, B., Wischnewsky, G. G., (1991) Anal. Chim. Acta, 243, pp. 221-225
Turner, M. J., Rosen, G. M., (1986) J. Med. Chem., 29, pp. 2439-2444
Pou, S., Ramos, C. L., Gladwell, T., Renks, E., Centra, M., Young, D., Cohen, M. C., Rosen, G. M., (1994) Anal. Biochem., 217, pp. 76-83
Buettner, G. R., Oberley, L. W., (1978) Biochem. Biophys. Res. Commun., 83, pp. 69-74
Aruoma, O. I., Halliwell, B., Gajewski, E., Dizdaroglu, M., (1991) Biochem. J., 273, pp. 601-604
Simic, M. G., (1990) Method in Enzymology, 186, pp. 89-100. , L. Packer, A. N. Glazer (Eds.), Academic Press, San Diego
Timmins, G. S., Liu, K. J., Bechara, E. J. H., Kotake, Y., Swartz, H. M., (1999) Free Radic. Biol. Med., 27, pp. 329-333
Bonomo, R. P., Marchelli, R., Tabb, G., (1995) J. Inorg. Biochem., 60, pp. 205-218
Mi, L., Zuberb hler, A. D., (1992) Helv. Chim. Acta, 75, pp. 1547-1556
Buxton, G. V., Greenstock, C. L., Helman, W. P., Ross, A. B., (1988) J. Phys. Chem. Ref. Data, 17, pp. 513-886
Baker, M. Z., Badiello, R., Tamba, M., Quintiliani, M., Gorin, G., (1982) Int. J. Radiat. Biol., 41, pp. 595-602
Eberhardt, M. K., Ramirez, G., Ayala, E., (1989) J. Org. Chem., 54, pp. 5922-5926
Johnson, G. R. A., Nazhat, N. B., (1987) J. Am. Chem. Soc., 109, pp. 1990-1994
Cabelli, D. E., Bielski, B. H. J., Holcman, J., (1987) J. Am. Chem. Soc., 109, pp. 3665-3669
Ettinger, K. V., Forrester, A. R., Hunter, C. H., (1982) Can. J. Chem., 60, pp. 1549-1559
Thornalley, P. J., Stern, A., (1984) Carbohydr. Res., 134, pp. 191-204
Schuchmann, M. N., Von Sonntag, C., (1978) Int. J. Radiat. Biol., 34, pp. 397-400
Deeble, D. J., Bothe, E., Schuchmann, H. P., Parsons, B. J., Phillips, G. O., Von Sonntag, C., (1990) Z. Naturforsch. C, 45, pp. 1031-1043
ESR study of the non-enzymic scission of xyloglucan by an ascorbate-H2O2-copper system: The involvement of the hydroxyl radical and the degradation of ascorbate
Xyloglucan is degraded by a mixture of copper(II), hydrogen peroxide and ascorbate. In the presence of ascorbate and/or hydrogen peroxide, copper(II) species were rapidly reduced to copper(I), which react with hydrogen peroxide. Spin-trapping experiments showed that hydroxyl radicals formed and attacked xyloglucan causing its degradation. The formation of a carbon-centred ascorbyl (C-ascorbyl) radical and its degradation with the formation of oxalate, was also caused by hydroxyl radicals. As a consequence, the features of the bis(oxalate) copper(II) complex clearly appeared in the frozen solution ESR spectra. The formation of carbon-centred radicals on the xyloglucan is the trigger for a series of possible molecular rearrangements which led to its oxidative scission. © 2001 Elsevier Science B.V. All rights reserved.
Xyloglucan is degraded by a mixture of copper(II), hydrogen peroxide and ascorbate. In the presence of ascorbate and/or hydrogen peroxide, copper(II) species were rapidly reduced to copper(I), which react with hydrogen peroxide. Spin-trapping experiments showed that hydroxyl radicals formed and attacked xyloglucan causing its degradation. The formation of a carbon-centred ascorbyl (C-ascorbyl) radical and its degradation with the formation of oxalate, was also caused by hydroxyl radicals. As a consequence, the features of the bis(oxalate) copper(II) complex clearly appeared in the frozen solution ESR spectra. The formation of carbon-centred radicals on the xyloglucan is the trigger for a series of possible molecular rearrangements which led to its oxidative scission. © 2001 Elsevier Science B.V. All rights reserved.
ESR study of the non-enzymic scission of xyloglucan by an ascorbate-H2O2-copper system: The involvement of the hydroxyl radical and the degradation of ascorbate
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ESR study of the non-enzymic scission of xyloglucan by an ascorbate-H2O2-copper system: The involvement of the hydroxyl radical and the degradation of ascorbate
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Int J Pharm (ISSN: 0378-5173, 1873-3476), 2017; 525(1): 275-281.
Impact Factor: 3.862
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Antoniali G, Lirussi L, D'Ambrosio C, Dal Piaz F, Vascotto C, Casarano E, Marasco D, Scaloni A, Fogolari F, Tell G
* SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements (548 views)
Mol Biol Cell (ISSN: 1059-1524), 2014 Feb 15; 25(4): 532-547.
Impact Factor: 4.466
View Export to BibTeX Export to EndNote
Faiella M, Maglio O, Nastri F, Lombardi A, Lista L, Hagen WR, Pavone V
* De Novo Design, Synthesis and Characterisation of MP3, A New Catalytic Four-Helix Bundle Hemeprotein (480 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2012 Dec 7; 18(50): 15960-15971.
Impact Factor: 5.831
View Export to BibTeX Export to EndNote
De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (893 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
View Export to BibTeX Export to EndNote
Nastri F, Lista L, Ringhieri P, Vitale R, Faiella M, Andreozzi C, Travascio P, Maglio O, Lombardi A, Pavone V
* A Heme-Peptide Metalloenzyme Mimetic with Natural Peroxidase-Like Activity (450 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Apr; 17(16): 4444-4453.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Bonomo RP, D'Alessandro F, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
* Carcinine-beta-cyclodextrin derivatives as scavenger entities of (OH) radicals and SOD-like properties of their copper(II) complexes (284 views)
Inorg Chim Acta (ISSN: 0020-1693), 2008 May 5; 361(6): 1705-1714.
Impact Factor: 1.94
View Export to BibTeX Export to EndNote
Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (495 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
View Export to BibTeX Export to EndNote
Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (693 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
View Export to BibTeX Export to EndNote
Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (378 views)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
View Export to BibTeX Export to EndNote
Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (351 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
View Export to BibTeX Export to EndNote
Pedone E, Bartolucci S, Fiorentino G
* Sensing and adapting to environmental stress: The Archaeal tactic (327 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2004 Sep 1; 9: 2909-2926.
Impact Factor: 3.226
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Tabbì G, Cassino C, Cavigiolio G, Colangelo D, Ghiglia A, Viano I, Osella D
* Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process (652 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2002 Dec 19; 45(26): 5786-5796.
Impact Factor: 4.566
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La Mendola D, Sortino S, Rizzarelli E, Vecchiog
* Synthesis Of New Carnosine Derivatives Of R-Cyclodextrin And Their Hydroxyl Radical Scavanger Ability (321 views)
Helvetica Chimica Acta, 2002; 85: 1633-1643.
Impact Factor: 1.394
View Export to BibTeX Export to EndNote
Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (1166 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
View Export to BibTeX Export to EndNote
Gurrieri S, Miceli L, Lanza CM, Tomaselli F, Bonomo RP, Rizzarelli E
Chemical characterization of Sicilian prickly pear (Opuntia ficus indica) and perspectives for the storage of its juice (292 views)
J Agric Food Chem (ISSN: 0021-8561), 2000 Nov; 48(11): 5424-5431.
Impact Factor: 1.56
View Export to BibTeX Export to EndNote
Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (602 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
View Export to BibTeX Export to EndNote
Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (699 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
View Export to BibTeX Export to EndNote
Pacelli R, Taira J, Cook JA, Wink DA, Krishna MC
Hydroxyurea reacts with heme proteins to generate nitric oxide [6] (369 views)
Lancet (ISSN: 0140-6736), 1996 Mar 30; 347(9005): 900-900.
Impact Factor: 16.135
View Export to BibTeX Export to EndNote
Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (367 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
View Export to BibTeX Export to EndNote
Wink DA, Cook JA, Pacelli R, Liebmann J, Krishna MC, Mitchell JB
Nitric oxide (NO) protects against cellular damage by reactive oxygen species (545 views)
Toxicology Letters (ISSN: 0378-4274), 1995 Dec; 82-3: 221-226.
Impact Factor: 1.128
View Export to BibTeX Export to EndNote
Bonomo RP, Marchelli R, Tabbì G
Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides (513 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Nov 15; 60(3): 205-218.
Impact Factor: 1.342
View Export to BibTeX Export to EndNote
Pacelli R, Wink DA, Cook JA, Krishna MC, DeGraff W, Friedman N, Tsokos M, Samuni A, Mitchell JB
NITRIC-OXIDE POTENTIATES HYDROGEN PEROXIDE-INDUCED KILLING OF ESCHERICHIA-COLI (428 views)
Journal Of Experimental Medicine (ISSN: 0022-1007), 1995 Nov 1; 182(5): 1469-1479.
Impact Factor: 14.384
View Export to BibTeX Export to EndNote
Condorelli G, Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
INHIBITION OF PHOTOHEMOLYSIS BY COPPER(II) COMPLEXES WITH SOD-LIKE ACTIVITY (504 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Jun; 54(4): 257-265.
Impact Factor: 1.342
View Export to BibTeX Export to EndNote
Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (616 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
View Export to BibTeX Export to EndNote
* Quantification of hydroxyl exchange of D-Glucose at physiological conditions for optimization of glucoCEST MRI at 3, 7 and 9. 4 Tesla (142 views)
Nmr Biomed (ISSN: 0952-3480linking, 1099-1492electronic), 2019 Sep; 32(9): e4113-e4113.
Impact Factor: 2.983
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Dell'Acqua S, Bacchella C, Monzani E, Nicolis S, Di Natale G, Rizzarelli E, Casella L
* Prion Peptides Are Extremely Sensitive to Copper Induced Oxidative Stress (618 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2017 Sep 18; 56(18): 11317-11325.
Impact Factor: 4.7
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Longo DL, Moustaghfir FZ, Zerbo A, Consolino L, Anemone A, Bracesco M, Aime S
* EXCI-CEST: Exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging (503 views)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2017; 525(1): 275-281.
Impact Factor: 3.862
View Export to BibTeX Export to EndNote
Antoniali G, Lirussi L, D'Ambrosio C, Dal Piaz F, Vascotto C, Casarano E, Marasco D, Scaloni A, Fogolari F, Tell G
* SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements (548 views)
Mol Biol Cell (ISSN: 1059-1524), 2014 Feb 15; 25(4): 532-547.
Impact Factor: 4.466
View Export to BibTeX Export to EndNote
Faiella M, Maglio O, Nastri F, Lombardi A, Lista L, Hagen WR, Pavone V
* De Novo Design, Synthesis and Characterisation of MP3, A New Catalytic Four-Helix Bundle Hemeprotein (480 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2012 Dec 7; 18(50): 15960-15971.
Impact Factor: 5.831
View Export to BibTeX Export to EndNote
De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (893 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
View Export to BibTeX Export to EndNote
Nastri F, Lista L, Ringhieri P, Vitale R, Faiella M, Andreozzi C, Travascio P, Maglio O, Lombardi A, Pavone V
* A Heme-Peptide Metalloenzyme Mimetic with Natural Peroxidase-Like Activity (450 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Apr; 17(16): 4444-4453.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Bonomo RP, D'Alessandro F, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
* Carcinine-beta-cyclodextrin derivatives as scavenger entities of (OH) radicals and SOD-like properties of their copper(II) complexes (284 views)
Inorg Chim Acta (ISSN: 0020-1693), 2008 May 5; 361(6): 1705-1714.
Impact Factor: 1.94
View Export to BibTeX Export to EndNote
Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (495 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
View Export to BibTeX Export to EndNote
Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (693 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
View Export to BibTeX Export to EndNote
Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (378 views)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
View Export to BibTeX Export to EndNote
Russo M, Tedesco I, Iacomino G, Palumbo R, Galano G, Russo GL
* Dietary phytochemicals in chemoprevention of cancer (351 views)
Curr Med Chem (ISSN: 1568-0134), 2005; 5(1): 61-72.
Impact Factor: 3.715
View Export to BibTeX Export to EndNote
Pedone E, Bartolucci S, Fiorentino G
* Sensing and adapting to environmental stress: The Archaeal tactic (327 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2004 Sep 1; 9: 2909-2926.
Impact Factor: 3.226
View Export to BibTeX Export to EndNote
Tabbì G, Cassino C, Cavigiolio G, Colangelo D, Ghiglia A, Viano I, Osella D
* Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process (652 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2002 Dec 19; 45(26): 5786-5796.
Impact Factor: 4.566
View Export to BibTeX Export to EndNote
La Mendola D, Sortino S, Rizzarelli E, Vecchiog
* Synthesis Of New Carnosine Derivatives Of R-Cyclodextrin And Their Hydroxyl Radical Scavanger Ability (321 views)
Helvetica Chimica Acta, 2002; 85: 1633-1643.
Impact Factor: 1.394
View Export to BibTeX Export to EndNote
Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (1166 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
View Export to BibTeX Export to EndNote
Gurrieri S, Miceli L, Lanza CM, Tomaselli F, Bonomo RP, Rizzarelli E
Chemical characterization of Sicilian prickly pear (Opuntia ficus indica) and perspectives for the storage of its juice (292 views)
J Agric Food Chem (ISSN: 0021-8561), 2000 Nov; 48(11): 5424-5431.
Impact Factor: 1.56
View Export to BibTeX Export to EndNote
Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (602 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
View Export to BibTeX Export to EndNote
Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (699 views)
Arch Bioch Bioph (ISSN: 0003-9861, 0003-9861linking), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
View Export to BibTeX Export to EndNote
Pacelli R, Taira J, Cook JA, Wink DA, Krishna MC
Hydroxyurea reacts with heme proteins to generate nitric oxide [6] (369 views)
Lancet (ISSN: 0140-6736), 1996 Mar 30; 347(9005): 900-900.
Impact Factor: 16.135
View Export to BibTeX Export to EndNote
Wink DA, Grisham MB, Miles AM, Nims RW, Krishna MC, Pacelli R, Teague D, Poore CM, Cook JA, Ford PC
Determination of selectivity of reactive nitrogen oxide species for various substrates (367 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic, 0076-6879linking), 1996; 268: 120-130.
Impact Factor: 2.435
View Export to BibTeX Export to EndNote
Wink DA, Cook JA, Pacelli R, Liebmann J, Krishna MC, Mitchell JB
Nitric oxide (NO) protects against cellular damage by reactive oxygen species (545 views)
Toxicology Letters (ISSN: 0378-4274), 1995 Dec; 82-3: 221-226.
Impact Factor: 1.128
View Export to BibTeX Export to EndNote
Bonomo RP, Marchelli R, Tabbì G
Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides (513 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Nov 15; 60(3): 205-218.
Impact Factor: 1.342
View Export to BibTeX Export to EndNote
Pacelli R, Wink DA, Cook JA, Krishna MC, DeGraff W, Friedman N, Tsokos M, Samuni A, Mitchell JB
NITRIC-OXIDE POTENTIATES HYDROGEN PEROXIDE-INDUCED KILLING OF ESCHERICHIA-COLI (428 views)
Journal Of Experimental Medicine (ISSN: 0022-1007), 1995 Nov 1; 182(5): 1469-1479.
Impact Factor: 14.384
View Export to BibTeX Export to EndNote
Condorelli G, Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
INHIBITION OF PHOTOHEMOLYSIS BY COPPER(II) COMPLEXES WITH SOD-LIKE ACTIVITY (504 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Jun; 54(4): 257-265.
Impact Factor: 1.342
View Export to BibTeX Export to EndNote
Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (616 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
View Export to BibTeX Export to EndNote
26 Records (25 excluding Abstracts).
Total impact factor: 101.879 (85.744 excluding Abstracts).
Total 5 year impact factor: 127.392 (103.191 excluding Abstracts).
Total impact factor: 101.879 (85.744 excluding Abstracts).
Total 5 year impact factor: 127.392 (103.191 excluding Abstracts).
312 views. Last view on Thursday 01 June 2023, 15:07:00
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