Gastric emptying after sleeve gastrectomy: Statistical evidence of a controlled prospective study with gastric scintigraphy(342 views) Pilone V, Tramontano S, Di Micco R, Monda A, Hasani A, Izzo G, Vitiello A, Caprio MG, Cuocolo A, Forestieri P
Department of Medicine and Surgery, University of Salerno, Salerno, Italy
Department of Clinical Medicine and Surgery, University Federico II, Via Pansini 5, 80100 Naples, Italy
Department of Biomorphological and Functional Sciences, University Federico II, Naples, Italy
References: Baltasar, A., Serra, C., Pérez, N., Bou, R., Bengochea, M., Ferri, L., Laparoscopic sleeve gastrectomy: A multi-purpose bariatric operation (2005) Obes Surg, 15, pp. 1124-112
Gumbs, A.A., Gagner, M., Dakin, G., Sleeve gastrectomy for morbid obesity (2007) Obes Surg, 17, pp. 962-969
Braghetto, I., Korn, O., Valladares, H., Gutiérrez, L., Csendes, A., Debandi, A., Laparoscopic sleeve gastrectomy: Surgical technique, indications and clinical results (2007) Obes Surg, 17, pp. 1442-1450
Peterli, R., Wölnerhanssen, B., Peters, T., Devaux, N., Kern, B., Christoffel-Courtin, C., Improvement in glucose metabolism after bariatric surgery: Comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: A prospective randomized trial (2007) Ann Surg, 250, pp. 234-241
Tougas, G., Chen, Y., Coates, G., Paterson, W., Dallaire, C., Paré, P., Standardization of a simplified scintigraphic methodology for the assessment of gastric emptying in a multicenter setting (2000) Am J Gastroenterol, 95, pp. 78-86
Forestieri, P., (2008) Linee Guida e Stato dell'Arte della Chirurgia Bariatrica e Metabolica in Italia, , EdiSES Editore, Naples
Frezza, E.E., Reddy, S., Gee, L.L., Wachtel, M.S., Complications after sleeve gastrectomy for morbid obesity (2009) Obes Surg, 19, pp. 684-687
Cardoso-Junior, A., Vaz Coelho, L.G., Savassi-Rocha, P.R., Vignolo, M.C., Abrantes, M.M., De Almeida, A.M., Gastric emptying of solids and semisolids in morbidly obese and non obese subjects (2007) Obes Surg, 17, pp. 236-241
Gallagher, T.K., Geoghegan, J.G., Baird, A.W., Winter, D.C., Implications of altered gastrointestinal motility in obesity (2007) Obes Surg, 17, pp. 1399-1407
Wright, R.A., Krinsky, S., Fleeman, C., Trujillo, J., Teague, E., Gastric emptying in obesity (1983) Gastroenterology, 84, pp. 747-751
Akkary, E., Duffy, A., Bell, R., Deciphering the sleeve: Technique, indications, efficacy, and safety of sleeve gastrectomy (2008) Obes Surg, 18, pp. 1323-1329
Melissas, J., Daskalakis, M., Koukouraki, S., Askoxylakis, I., Metaxari, M., Dimitriadis, E., Sleeve gastrectomya "food limiting" operation (2008) Obes Surg, 18, pp. 1251-1256
Peterli, R., Wolnerhanssen, B., Peters, T., Devaux, N., Kern, B., Christoffel-Courtin, C., Improvement in glucose metabolism after bariatric surgery: Comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: A prospective randomized trial (2009) Ann Surg, 250, pp. 234-241
Gagner, M., Faster gastric emptying after laparoscopic sleeve gastrectomy (2010) Obes Surg, 20, pp. 964-965
Jung, H.J., Lee, J.H., Ryu, K.W., Lee, J.Y., Kim, C.G., Choi, I.J., The influence of reconstruction methods on food retention phenomenon in the remnant stomach after a subtotal gastrectomy (2008) J Surg Oncol, 98, pp. 11-14
Serra, C., Baltasar, A., Pérez, N., Bou, R., Bengochea, M., Total gastrectomy for complications of the duodenal switch, with reversal (2006) Obes Surg, 16, pp. 1082-1086
Braghetto, I., Davanzo, C., Korn, O., Csendes, A., Valladares, H., Herrera, E., Scintigraphic evaluation of gastric emptying in obese patients submitted to sleeve gastrectomy compared to normal subjects (2009) Obes Surg, 19, pp. 1515-1521
Shah, S., Shah, P., Todkar, J., Gagner, M., Sonar, S., Solav, S., Prospective controlled study of effect of laparoscopic sleeve gastrectomy on small bowel transit time and gastric emptying half-time in morbidly obese patients with type 2 diabetes mellitus (2010) Surg Obes Relat Dis, 6, pp. 152-157
Melissas, J., Koukouraki, S., Askoxylakis, J., Stathaki, M., Daskalakis, M., Perisinakis, K., Sleeve gastrectomy: A restrictive procedure? (2007) Obes Surg, 17, pp. 57-62
Bernstine, H., Tzioni-Yehoshua, R., Groshar, D., Beglaibter, N., Shikora, S., Rosenthal, R.J., Gastric emptying is not affected by sleeve gastrectomy-scintigraphic evaluation of gastric emptying after sleeve gastrectomy without removal of the gastric antrum (2009) Obes Surg, 19, pp. 293-298
Baumann, T., Kuesters, S., Grueneberger, J., Marjanovic, G., Zimmermann, L., Schaefer, A.O., Time-resolved MRI after ingestion of liquids reveals motility changes after laparoscopic sleeve gastrectomy - Preliminary results (2011) Obes Surg, 21, pp. 95-101
Gagner, M., Deitel, M., Kalberer, T.L., Erickson, A.L., Crosby, R.D., The Second International Consensus Summit for Sleeve Gastrectomy, March 19-21, 2009 (2009) Surg Obes Relat Dis, 5, pp. 476-485
Weiner, R.A., Weiner, S., Pomhoff, I., Jacobi, C., Makarewicz, W., Weigand, G., Laparoscopic sleeve gastrectomy - Influence of sleeve size and resected gastric volume (2007) Obes Surg, 17, pp. 1297-1305
Yehoshua, T.R., Eidelman, A.L., Stein, M., Fichman, S., Mazor, A., Chen, J., Laparoscopic sleeve gastrectomy - Volume and pressure assessment (2008) Obes Surg, 18, pp. 1083-1088
Gumbs, A. A., Gagner, M., Dakin, G., Sleeve gastrectomy for morbid obesity (2007) Obes Surg, 17, pp. 962-969
Peterli, R., W lnerhanssen, B., Peters, T., Devaux, N., Kern, B., Christoffel-Courtin, C., Improvement in glucose metabolism after bariatric surgery: Comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: A prospective randomized trial (2007) Ann Surg, 250, pp. 234-241
Frezza, E. E., Reddy, S., Gee, L. L., Wachtel, M. S., Complications after sleeve gastrectomy for morbid obesity (2009) Obes Surg, 19, pp. 684-687
Gallagher, T. K., Geoghegan, J. G., Baird, A. W., Winter, D. C., Implications of altered gastrointestinal motility in obesity (2007) Obes Surg, 17, pp. 1399-1407
Wright, R. A., Krinsky, S., Fleeman, C., Trujillo, J., Teague, E., Gastric emptying in obesity (1983) Gastroenterology, 84, pp. 747-751
Deane, A. M., Nguyen, N. Q., Stevens, J. E., Fraser, R. J., Holloway, R. H., Besanko, L. K., Endogeneous glucagonlike peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia (2009) J Clin Endocrinol Metab, 95, pp. 215-221
Jung, H. J., Lee, J. H., Ryu, K. W., Lee, J. Y., Kim, C. G., Choi, I. J., The influence of reconstruction methods on food retention phenomenon in the remnant stomach after a subtotal gastrectomy (2008) J Surg Oncol, 98, pp. 11-14
Weiner, R. A., Weiner, S., Pomhoff, I., Jacobi, C., Makarewicz, W., Weigand, G., Laparoscopic sleeve gastrectomy - Influence of sleeve size and resected gastric volume (2007) Obes Surg, 17, pp. 1297-1305
Yehoshua, T. R., Eidelman, A. L., Stein, M., Fichman, S., Mazor, A., Chen, J., Laparoscopic sleeve gastrectomy - Volume and pressure assessment (2008) Obes Surg, 18, pp. 1083-1088
Gastric emptying after sleeve gastrectomy: Statistical evidence of a controlled prospective study with gastric scintigraphy
Aim: Laparoscopic sleeve gastrectomy (LSG) is a stand-alone bariatric procedure, its feasibility and efficacy being confirmed by long-term data. The effect of the procedure is believed to be based on the gastric restriction and reduction of ghrelin. Nevertheless it remains still controversial the role of LSG on gastric emptying and the impact that this may have on weight loss outcomes. Our aim is to assess gastric emptying after LSG using gastric scintigraphy. Methods: For this prospective randomized study, 45 patients undergoing LSG at our Centre for the Multidisciplinary Treatment of Severe Obesity from April 2009 to April 2011 were enrolled and observed prospectively (Group A). The inclusion criteria followed the guidelines for bariatric surgery. All patients performed gastric emptying scintigraphy through a standard semisolid meal (250 kcal), marked with 0.5 mCiTc 99. Group A performed the exam before (A1) and after the operation (A2). A control group (Group B) included 20 patients undergoing scintigraphic assessment for other reasons. Results: LSG was performed following a standardized technique. No complications were observed. The scintigraphic study showed a reduced half-life tracer (Al vs. A2: 80.4±16.5 min vs. 64.3±22 min P=0.06), without a significant difference. Comparing the two groups no differences occurred before operation (B vs. A1). Gastric emptying time resulted significatively reduced in group A2 rather than in group A1 and B. Conclusion: Gastric motility plays a role in the pathogenesis of obesity. Our experience suggests that LSG reduces gastric emptying time, but further studies are necessary to reach statystical significativity.
Gastric emptying after sleeve gastrectomy: Statistical evidence of a controlled prospective study with gastric scintigraphy
No results.
Gastric emptying after sleeve gastrectomy: Statistical evidence of a controlled prospective study with gastric scintigraphy
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(288 views) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 ViewExport to BibTeXExport to EndNote
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(341 views) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 ViewExport to BibTeXExport to EndNote
Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G * CaMK4 gene deletion induces hypertension(349 views) J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D. Impact Factor:2.882 ViewExport to BibTeXExport to EndNote
Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, Tomaino C, Muraca MG, Leotta A, Lio SG, Pinessi L, Rainero I, Sorbi S, Nee L, Milan G, Pappata S, Postiglione A, Abbamondi N, Forloni G, St George Hyslop P, Rogaeva E, Bugiani O, Giaccone G, Foncin JF, Spillantini MG, Puccio G * Worldwide distribution of PSEN1 Met146Leu mutation: A large variability for a founder mutation(1002 views) Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2010 Mar 9; 74(10): 798-806. Impact Factor:8.017 ViewExport to BibTeXExport to EndNote
Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M * The EEE project(449 views) Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980. Impact Factor:0 ViewExport to BibTeXExport to EndNote
Vitiello M, Finamore E, Falanga A, Raieta K, Cantisani M, Galdiero F, Pedone C, Galdiero M, Galdiero S * Fusion in Coq(481 views) Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2001; 2178LNCS: 583-596. Impact Factor:0.415 ViewExport to BibTeXExport to EndNote