Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent(394 views) Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Keywords: Bombesin Peptide, Doxorubicin Delivery, Gastrin-Releasing Peptide Receptors, Pc-3 Cells, Theranostic Applications, 2 Distearoyl Sn Glycero 3 Phosphocholine, Bombesin Receptor, Macrogol, Monomer, Mony Bn, Phospholipid, Unclassified Drug, 2 Distearoyllecithin, 2-Distearoyllecithin, Antineoplastic Agent, Bombesin (7 14), Bombesin (7-14), Drug Carrier, Drug Derivative, Liposome, Pentetic Acid, Peptide Fragment, Phosphatidylcholine, Surfactant, Animal Experiment, Animal Model, Antineoplastic Activity, Article, Binding Affinity, Cancer Cell Culture, Cancer Cell Destruction, Cancer Inhibition, Cell Adhesion, Cell Survival, Chemical Composition, Controlled Study, Cytotoxicity Test, Encapsulation, Female, Human, Human Cell, In Vitro Study, In Vivo Study, Liposomal Delivery, Mouse, Nonhuman, Prostate Cancer, Protein Expression, Protein Localization, Protein Targeting, Tumor Xenograft, Upregulation, Bagg Albino Mouse, Chemistry, Drug Antagonism, Drug Delivery System, Drug Screening, Metabolism, Nanomedicine, Nude Mouse, Pathology, Prostate Tumor, Tumor Cell Line, Inbred Balb C, Prostatic Neoplasms, Surface-Active Agents, Xenograft Model Antitumor Assays,
Affiliations: *** IBB - CNR ***
CIRPeB, Department of Biological Sciences and IBB CNR, University of Naples 'Federico II', Napoli, Italy
Department of Pharmaceutical Chemistry, University of Naples 'Federico II', Italy
Department of Nuclear Medicine, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione 'G. Pascale', Italy
Department of Experimental Pharmacology, University of Naples 'Federico II', Napoli, Italy
References: Not available.
Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent