Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors (484 views)
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.554, 5-year impact factor: 1.33
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84877602711&partnerID=40&md5=4a3ffbaffc4275e359658cc49ac1e867
Keywords: Doxorubicin, Liposomes, Nanosystems, Peptides, Polymeric Micelles, Theranostics, Multifunctional Compounds, Personalized Medicines, Simultaneous Imaging, Targeting Peptides, Therapeutic Modality, Diagnosis, Disease Control, Drug Therapy,
Affiliations:
*** IBB - CNR ***
Department of Biological Sciences, IBB CNR, University of Naples 'Federico II', Via Mezzocannone, 16, Napoli 80134, Italy
References:
Byrne, J.D., Betancourt, T., Brannon-Pppas, L., Active targeting schemes for nanoparticle systems in cancer therapeutics (2008) Adv. Drug Delivery Rev., 60, pp. 1615-162
Janib, S.M., Moses, A.S., MacKay, J.A., Imaging and drug delivery using theranostic nanoparticles (2010) Adv. Drug. Delivery Rev., 62, pp. 1052-1063
Smith-Jones, P.M., Bischof, C., Leimer, M., Gludovacz, D., Angelberger, P., Pangerl, T., Peck-Radosavljevic, M., Virgolini, I., DOTA-lanreotide: A novel somatostatin analog for tumor diagnosis and therapy (1999) Endocrinology, 140, pp. 5136-5148
Aloj, L., Panico, M., Caraco, C., Del Vecchio, S., Arra, C., Affuso, A., Tesauro, D., Salvatore, M., In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (2004) Journal of Nucl. Med., 45, pp. 485-494
Rogers, B.E., Bigott, H.M., McCarthy, D.W., Della Manna, D., Kim, J., Sharp, T.L., Welch, M.J., MicroPET imaging of a gastrin-releasing peptide receptor-positive tumor in a mouse model of human prostate cancer using a 64Cu-labeled bombesin analogue (2003) Bioconjug. Chem., 14, pp. 756-763
Farokhzad, O.C., Karp, J.M., Langer, R., Nanoparticle aptamer bioconjugates for cancer targeting (2006) Expert Opinion Drug Delivery, 3, pp. 311-324
Torchilin, V., Antibody-modified liposomes for cancer chemotherapy (2008) Expert Opinion on Drug Delivery, 5, pp. 1003-1025
Sofou, S., Sgouros, G., Antibody-targeted liposomes in cancer therapy and imaging (2008) Expert Opinion on Drug Delivery, 5, pp. 189-204
Wu, H., Chang, D.-K., Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy (2010) Journal of Oncology, 2010, pp. 723-798
James, J.S., Dubs, G., FDA approves new kind of lymphoma treatment (1997) AIDS Treat News, 284, pp. 2-3
Albanell, J., Baselga, J., Trastuzumab: A humanized anti-HER2 monoclonal antibody, for the treatment of breast cancer (1999) Drugs Today, 35, pp. 931-946
Ferrara, N., VEGF as a therapeutic target in cancer (2005) Oncology, 69, pp. 11-16
Van Cutsem, E., Kohne, C.H., Hitre, E., Zaluski, J., Chang Chien, C.-R., Makhson, A., D'Haens, G., Rougier, P., Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer (2009) N. Engl. J. Med., 360, pp. 1408-1417
Murdaca, G., Colombo, B.M., Puppo, F., Adalimumab for the treatment of immunemediated diseases: An update on old and recent indications (2011) Drugs of Today, 47, pp. 277-288
Wilson, D.S., Szostak, J.W., In vitro selection of functional nucleic acids (1999) Ann. Rev. Biochem., 68, pp. 611-647
Bates, P.J., Kahlon, J.B., Thomas, S.D., Trent, J.O., Miller, D.M., Antiproliferative activity of G-rich oligonucleotides correlates with protein binding (1999) J. Biol. Chem., 274, pp. 26369-26377
Bates, P.J., Laber, D.A., Miller, D.M., Thomas, S.D., Trent, J.O., Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer (2009) Exp. Mol. Pathol., 86, pp. 151-164
Mongelard, F., Bouvet, P., AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia (2010) Curr. Opin. Mol. Ther., 12, pp. 107-114
Bouchard, P.R., Hutabarat, R.M., Thompson, K.M., Discovery and development of therapeutic aptamers (2010) Annu Rev Pharmacol. Toxicol., 50, pp. 237-257
Beekman, K.W., Colevas, A.D., Cooney, K., Dipaola, R., Dunn, R.L., Gross, M., Keller, E.T., Hussain, M., Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: Scientific rationale and study design (2006) Clin. Genitourin. Cancer, 4, pp. 299-302
Wang, A.Z., Gu, F., Zhang, L., Chan, J.M., Radovic-Moreno, A., Shaikh, M.R., Farokhzad, O.C., Biofunctionalized targeted nanoparticles for therapeutic applications (2008) Expert Opin. Biol. Ther., 8, pp. 1063-1070
Ladner, R.C., Sato, A.K., Gorzelany, J., De Souza, M., Phage display-derived peptides as therapeutic alternatives to antibodies (2004) Drug Discovery Today, 9, pp. 525-529
Jarzyna, P.A., Gianella, A., Skajaa, T., Knudsen, G., Deddens, L.H., Cormode, D.P., Fayad, Z.A., Mulder, W.J.M., Multifunctional imaging nanoprobes. Wiley Interdiscip (2010) Rev. Nanomed. Nanobiotechnol., 2, pp. 138-150
Mulder, W.J., Castermans, K., Van Beijnum, J.R., Oude Egbrink, M.G., Chin, P.T., Fayad, Z.A., Lowik, C.W., Nicolay, K., Molecular imagingof tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots (2009) Angiogenesis, 12, pp. 17-24
Willmann, J.K., Van Bruggen, N., Dinkelborg, L.M., Gambhir, S.S., Molecular imaging in drug development (2008) Nat. Rev. Drug Discovery, 7, pp. 591-607
Thakare, V.S., Das, M., Jain, A.K., Patil, S., Jain, S., Carbon nanotubes in cancer theragnosis (2010) Nanomedicine, 5, pp. 1277-1301
Liu, Y., Miyoshi, H., Nakamura, M., Nanomedicine for drug delivery and imaging: A promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles (2007) Int. J. Cancer, 120, pp. 2527-2537
Williams, D.F., On the nature of biomaterials (2009) Biomaterials, 30, pp. 5897-5909
Kim, K., Kim, J.H., Park, H., Kim, Y.S., Park, K., Nam, H., Lee, S., Kwon, I.C., Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring (2010) J. Control. Release, 146, pp. 219-227
Yang, X., Hong, H., Grailer, J.J., Rowland, I.J., Javadi, A., Hurley, S.A., Xiao, Y., Gong, S., CRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging (2011) Biomaterials, 32, pp. 4151-4160
Nasongkla, N., Shuai, X.T., Ai, H., Ai, H., Weinberg, B.D., Pink, J., Boothman, D.A., Gao, J., CRGD functionalized polymer micelles for targeted doxorubicin delivery (2004) Angew. Chem. Int. Ed. Engl., 43, pp. 6323-6327
Singh, R., Lillard, J.W., Nanoparticles-based targeted drug delivery (2009) Exper. Mol. Pathol., 86, pp. 215-223
Yu, M.K., Park, J., Jon, S., Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy (2012) Theranostic, 2, pp. 3-44
Park, K., Lee, S., Kang, E., Kim, K., Choi, K., Kwon, I.C., New generation of multifunctional nanoparticles for cancer imaging and therapy (2009) Adv. Funct. Mater., 19, pp. 1553-1566
Petros, R.A., Desimone, J.M., Strategies in the design of nanoparticles for therapeutic applications (2010) Nat. Rev. Drug Discovery, 9, pp. 615-627
Greish, K., Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting (2010) Cancer Nanotechnology Methods in Molecular Biology, 624, pp. 25-37. , eds. (Stephen R. Grobmyer, B. M. M.) Springer, Univ Florida
Maeda, H., Wu, J., Sawa, T., Hori, K., Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review (2000) J. Control. Release, 65, pp. 271-284
Matsumura, Y., Maeda, H., A new concept for macromolecular therapies in cancer chemotherapy: Mechanisms of tumor tropic accumulation of proteins and the antitumor agents smancs (1986) Cancer Res., 6, pp. 6397-6392
Danhier, F., Feron, O., Preat, V., To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery (2010) J. Control. Release, 148, pp. 135-146
Lasic, D.D., Papahadjopoulos, D., (1998) Medical Applications of Liposomes, , Elsevier Science, Amsterdam
Hortobagyi, G.N., Anthracyclines in the treatment of cancer: An overview (1997) Drugs, 54, pp. 1-7
Gabizon, A., Martin, F., Polyethylene glycol-coated (pegylated) liposomal Doxorubicin: Rationale for use in solid tumors (1997) Drugs, 54, pp. 15-21
Gabizon, A., Pharmacokinetics of PEGylated liposomal Doxorubicin (2003) Clin. Pharmacokinet., 42, pp. 419-436
Abraham, S.A., Waterhouse, D.N., Lawrence, D., Cullis, P.R., Madden, T.D., Bally, M.B., The liposomal formulation of doxorubicin (2005) Methods Enzymol., 391, pp. 71-97
Murphy, E.A., Majeti, B.K., Barnes, L.A., Makale, M., Weis, S.M., Lutu-Fuga, K., Wrasidlo, W., Cheresh, D.A., Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis (2008) PNAS, 105, pp. 9343-9348
Gasparini, G., Brooks, P.C., Biganzoli, E., Vermeulen, P.B., Bonoldi, E., Dirix, L.Y., Ranieri, G., Cheresh, D.A., Vascular integrin avb3: A new prognostic indicator in breast cancer (1998) Clin. Cancer Res., 4, pp. 2625-2634
He, X., Na, M.H., Kim, J.S., Lee, G.-Y., Park, J.Y., Hoffman, A.S., Nam, J.O., Lee, B.-H., A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor (2011) Mol. Pharmaceutics, 8, pp. 430-438
Accardo, A., Morisco, A., Tesauro, D., Pedone, C., Morelli, G., Naposomes: A new class of peptide derivatized target selective multimodal nanoparticles for imaging and therapeutic applications (2011) Therapeutic Delivery, 2, pp. 235-257
Vaccaro, M., Mangiapia, G., Radulescu, A., Schille'N, K., D'Errico, G., Morelli, G., Paduano, L., Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: Physico-chemical characterization (2009) Soft Matter, 5, pp. 2504-2512
Reubi, J.C., Schaer, J.C., Waser, B., Cholecystokinin (CCK) -A and CCK-B/gastrin receptors in human tumors (1997) Cancer Res., 57, pp. 1377-1386
Dufresne, M., Seva, C., Fourmy, D., Cholecystokinin and gastrin receptors (2006) Physiol. Rev., 86, pp. 805-847
Markwalder, R., Reubi, J.C., Gastrin-releasing peptide receptors in the human prostate: Relation to neoplastic transformation (1999) Cancer Res., 59, pp. 1152-1159
Gugger, M., Reubi, J.C., Gastrin-releasing peptide receptors in non-neoplastic and neoplastic tuman breast (1999) Am. J. Pathol., 155, pp. 2067-2076
Fleischmann, A., Waser, B., Reubi, J.C., Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms (2007) Cell. Oncol., 29, pp. 421-433
Reubi, J.C., Waser, B., Schaer, J.C., Laissue, J.A., Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands (2001) Eur. J. Nucl. Med., 28, pp. 836-846
Bell, G., Reisine, T., Molecular biology of somatostatin receptors (1993) Trends Neurosci., 16, pp. 34-38
Reubi, J.C., Horisberger, U., Laissue, J., High density of somatostatin receptors in veins surrounding human cancer tissue: Role in tumor host interaction? (1994) Int. J. Cancer, 56, pp. 681-688
Accardo, A., Tesauro, D., Aloj, L., Tarallo, L., Arra, C., Mangiapia, G., Vaccaro, M., Morelli, G., Peptide containing aggregates as selective nanocarriers for therapeutics (2008) ChemMedChem, 3, pp. 594-602
Morisco, A., Accardo, A., Tesauro, D., Palumbo, R., Benedetti, E., Morelli, G., Peptidelabeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (2011) Biopolymers (Peptide Sciences), 96, pp. 88-96
Accardo, A., Salzano, G., Morisco, A., Aurilio, M., Parisi, A., Maione, F., Cicala, C., Morelli, G., Peptide modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (2012) Int. J. Nanomed., 7, pp. 2007-2017
Jones, M., Leroux, J., Polymeric micelles - A new generation of colloidal drug carriers (1999) Eur. J. Pharm. Biopharm., 48, pp. 101-111
Sutton, D., Nasongkla, N., Blanco, E., Gao, J., Functionalized micellar systems for cancer targeted drug delivery (2007) Pharm. Res., 24, pp. 1029-1046
Shuai, X., Ai, H., Nasongkla, N., Kim, S., Gao, J., Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery (2004) J. Control. Release, 98, pp. 415-426
Rowe, M.D., Thamm, D.H., Kraft, S.L., Boyes, S.G., Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer (2009) Biomacromolecules, 10, pp. 983-993
Xiao, Y., Hong, H., Javadi, A., Engle, J.W., Xu, W., Yang, Y., Zhang, Y., Gong, S., Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging (2012) Biomaterials, 33, pp. 3071-3082
Hong, H.-Y., Lee, H.Y., Kwak, W., Yoo, J., Na, M.-H., So, I.S., Kwon, T.-H., Lee, B.-H., Phage display selection of peptides that home to atherosclerotic plaques: IL-4 receptor as a candidate target in atherosclerosis (2008) J. Cell. Mol. Med., 12, pp. 2003-2014
Park, K., Hong, H.-Y., Moon, H.J., Lee, B.-H., Kim, I.-S., Kwon, I.C., Rhee, K., A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides (2008) J. Control. Release, 128, pp. 217-223
Wu, X.L., Kim, J.H., Koo, H., Bae, S.M., Shin, H., Kim, M.S., Lee, B.-H., Lee, D.S., Tumor-targeting peptide conjugated pH responsive micelles as a potential drug carrier for cancer therapy (2010) Bioconjugate Chem., 21, pp. 208-213
Christian, S., Pilch, J., Akerman, M.E., Porkka, K., Laakkonen, P., Ruoslahti, E., Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels (2003) J. Cell. Biol., 163, pp. 871-878
Reddy, G.R., Bhojani, M.S., McConville, P., Moody, J., Moffat, B.A., Hall, D.E., Kim, G., Ross, B.D., Vascular targeted nanoparticles for imaging and treatment of brain tumors (2006) Clin. Cancer Res., 12, pp. 6677-6686
Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J.S., Chin, S.-F., Gao, J., Multifunctional polymeric micelles as cancertargeted, MRI-ultrasensitive drug delivery systems (2006) Nano Lett., 6, pp. 2427-2430
Blanco, E., Kessinger, C.W., Sumer, B.D., Gao, J., Multifunctional micellar nanomedicine for cancer therapy (2009) Experimental Biology and Medicine, 234, pp. 123-131
Guthi, J.S., Yang, S.-G., Huang, G., Li, S., Khemtong, C., Kessinger, C.W., Peyton, M., Gao, J., MRI-visible micellar nanomedicine for targeted drug delivery tolung cancer cells (2010) Mol. Pharmaceutics, 7, pp. 32-40
Gianella, A., Jarzyna, P.A., Mani, V., Ramachandran, S., Calcagno, C., Tang, J., Kann, B., Mulder, W.J.M., Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer (2011) Nano Acs, 5, pp. 4422-4433
Simberg, D., Duza, T., Park, J.H., Essler, M., Pilch, J., Zhang, L., Derfus, A.M., Ruoslahti, E., Biomimetic amplification of nanoparticle homing to tumors (2007) PNAS, 104, pp. 932-936
Agemy, L., Sugahara, K.N., Kotamraju, V.R., Gujraty, K., Girard, O.M., Kono, Y., Mattrey, R.F., Ruoslahti, E., Nanoparticle-induced vascular blockade in human prostate cancer (2010) Blood, 116, pp. 2847-2856
Agemy, L., Friedmann-Morvinski, D., Kotamraju, V.R., Roth, L., Sugahara, K.N., Girard, O.M., Mattrey, R.F., Ruoslahti, E., Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma (2011) PNAS, 108, pp. 17450-17455
Wang, Y., Leaf, H., Multifunctional theranostic nanoparticles for brain tumors (2012) Molecular Therapy, 20, pp. 10-11
Mok, H., Veiseh, O., Fang, C., Kievit, F.M., Wang, F.Y., Park, J.O., Zhang, M., PHSensitive SiRNA nanovector for targeted gene silencing and cytotoxic effect in cancer cells (2010) Mol. Pharm., 7, pp. 1930-1939
Lyons, S.A., O'Neal, J., Sontheimer, H., Chlorotoxin a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin (2002) Glia, 39, pp. 162-173
Kumar, M., Yigit, M., Dai, G., Moore, A., Medarova, Z., Image-guided breast tumor therapy using a small interfering RNA nanodrug (2010) Cancer Res., 70, pp. 7553-7561
Von Maltzahn, G., Park, J.H., Lin, K.Y., Singh, N., Schwoppe, C., Mesters, R., Berdel, W.E., Bhatia, S.N., Nanoparticles that communicate in vivo to amplify tumor targeting (2011) Nat. Mater., 10, pp. 545-552
Park, J.H., Von Maltzahn, G., Zhang, L., Schwartz, M.P., Ruoslahtim, E., Bhatia, S.N., Sailor, M.J., Magnetic iron oxide nanoworms for tumor targeting and imaging (2008) Adv. Mater., 20, pp. 1630-1715
Alivisatos, A.P., Semiconductor clusters, nanocrystals, and quantum dots (1996) Science, 271, pp. 933-937
Bruchez, M., Moronne, M., Gin, P., Weiss, S., Alivisatos, A.P., Semiconductor nanocrystals as fluorescent biological labels (1998) Science, 281, pp. 2013-2016
Hu, R., Yong, K.-T., Roy, I., Ding, H., Law, W.-C., Cai, H., Zhang, X., Prasad, P.N., Functionalized near-infrared quantum dots for in vivo tumor vasculature imaging (2010) Nanotechnology, 21, p. 145105
Cheng, S.-H., Lee, C.-H., Chen, M.-C., Souris, J.S., Tseng, F.-G., Yang, C.-S., Mou, C.-Y., Lo, L.-W., Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics - The trio of imaging, targeting and therapy (2010) J. Mater. Chem., 20, pp. 6149-6157
Ashley, C.E., Carnes, E.C., Phillips, G.K., Padilla, D., Durfee, P.N., Brown, P.A., Hanna, T.N., Brinker, C.J., The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers (2011) Nature Materials, 10, pp. 389-397
Byrne, J. D., Betancourt, T., Brannon-Pppas, L., Active targeting schemes for nanoparticle systems in cancer therapeutics (2008) Adv. Drug Delivery Rev., 60, pp. 1615-162
Janib, S. M., Moses, A. S., MacKay, J. A., Imaging and drug delivery using theranostic nanoparticles (2010) Adv. Drug. Delivery Rev., 62, pp. 1052-1063
Smith-Jones, P. M., Bischof, C., Leimer, M., Gludovacz, D., Angelberger, P., Pangerl, T., Peck-Radosavljevic, M., Virgolini, I., DOTA-lanreotide: A novel somatostatin analog for tumor diagnosis and therapy (1999) Endocrinology, 140, pp. 5136-5148
Rogers, B. E., Bigott, H. M., McCarthy, D. W., Della Manna, D., Kim, J., Sharp, T. L., Welch, M. J., MicroPET imaging of a gastrin-releasing peptide receptor-positive tumor in a mouse model of human prostate cancer using a 64Cu-labeled bombesin analogue (2003) Bioconjug. Chem., 14, pp. 756-763
Farokhzad, O. C., Karp, J. M., Langer, R., Nanoparticle aptamer bioconjugates for cancer targeting (2006) Expert Opinion Drug Delivery, 3, pp. 311-324
Wu, H., Chang, D. -K., Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy (2010) Journal of Oncology, 2010, pp. 723-798
James, J. S., Dubs, G., FDA approves new kind of lymphoma treatment (1997) AIDS Treat News, 284, pp. 2-3
Wilson, D. S., Szostak, J. W., In vitro selection of functional nucleic acids (1999) Ann. Rev. Biochem., 68, pp. 611-647
Bates, P. J., Kahlon, J. B., Thomas, S. D., Trent, J. O., Miller, D. M., Antiproliferative activity of G-rich oligonucleotides correlates with protein binding (1999) J. Biol. Chem., 274, pp. 26369-26377
Bates, P. J., Laber, D. A., Miller, D. M., Thomas, S. D., Trent, J. O., Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer (2009) Exp. Mol. Pathol., 86, pp. 151-164
Bouchard, P. R., Hutabarat, R. M., Thompson, K. M., Discovery and development of therapeutic aptamers (2010) Annu Rev Pharmacol. Toxicol., 50, pp. 237-257
Beekman, K. W., Colevas, A. D., Cooney, K., Dipaola, R., Dunn, R. L., Gross, M., Keller, E. T., Hussain, M., Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: Scientific rationale and study design (2006) Clin. Genitourin. Cancer, 4, pp. 299-302
Wang, A. Z., Gu, F., Zhang, L., Chan, J. M., Radovic-Moreno, A., Shaikh, M. R., Farokhzad, O. C., Biofunctionalized targeted nanoparticles for therapeutic applications (2008) Expert Opin. Biol. Ther., 8, pp. 1063-1070
Ladner, R. C., Sato, A. K., Gorzelany, J., De Souza, M., Phage display-derived peptides as therapeutic alternatives to antibodies (2004) Drug Discovery Today, 9, pp. 525-529
Jarzyna, P. A., Gianella, A., Skajaa, T., Knudsen, G., Deddens, L. H., Cormode, D. P., Fayad, Z. A., Mulder, W. J. M., Multifunctional imaging nanoprobes. Wiley Interdiscip (2010) Rev. Nanomed. Nanobiotechnol., 2, pp. 138-150
Mulder, W. J., Castermans, K., Van Beijnum, J. R., Oude Egbrink, M. G., Chin, P. T., Fayad, Z. A., Lowik, C. W., Nicolay, K., Molecular imagingof tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots (2009) Angiogenesis, 12, pp. 17-24
Willmann, J. K., Van Bruggen, N., Dinkelborg, L. M., Gambhir, S. S., Molecular imaging in drug development (2008) Nat. Rev. Drug Discovery, 7, pp. 591-607
Thakare, V. S., Das, M., Jain, A. K., Patil, S., Jain, S., Carbon nanotubes in cancer theragnosis (2010) Nanomedicine, 5, pp. 1277-1301
Williams, D. F., On the nature of biomaterials (2009) Biomaterials, 30, pp. 5897-5909
Kim, K., Kim, J. H., Park, H., Kim, Y. S., Park, K., Nam, H., Lee, S., Kwon, I. C., Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring (2010) J. Control. Release, 146, pp. 219-227
Yu, M. K., Park, J., Jon, S., Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy (2012) Theranostic, 2, pp. 3-44
Petros, R. A., Desimone, J. M., Strategies in the design of nanoparticles for therapeutic applications (2010) Nat. Rev. Drug Discovery, 9, pp. 615-627
Lasic, D. D., Papahadjopoulos, D., (1998) Medical Applications of Liposomes, , Elsevier Science, Amsterdam
Hortobagyi, G. N., Anthracyclines in the treatment of cancer: An overview (1997) Drugs, 54, pp. 1-7
Abraham, S. A., Waterhouse, D. N., Lawrence, D., Cullis, P. R., Madden, T. D., Bally, M. B., The liposomal formulation of doxorubicin (2005) Methods Enzymol., 391, pp. 71-97
Murphy, E. A., Majeti, B. K., Barnes, L. A., Makale, M., Weis, S. M., Lutu-Fuga, K., Wrasidlo, W., Cheresh, D. A., Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis (2008) PNAS, 105, pp. 9343-9348
He, X., Na, M. H., Kim, J. S., Lee, G. -Y., Park, J. Y., Hoffman, A. S., Nam, J. O., Lee, B. -H., A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor (2011) Mol. Pharmaceutics, 8, pp. 430-438
Reubi, J. C., Schaer, J. C., Waser, B., Cholecystokinin (CCK) -A and CCK-B/gastrin receptors in human tumors (1997) Cancer Res., 57, pp. 1377-1386
Reubi, J. C., Waser, B., Schaer, J. C., Laissue, J. A., Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands (2001) Eur. J. Nucl. Med., 28, pp. 836-846
Reubi, J. C., Horisberger, U., Laissue, J., High density of somatostatin receptors in veins surrounding human cancer tissue: Role in tumor host interaction? (1994) Int. J. Cancer, 56, pp. 681-688
Rowe, M. D., Thamm, D. H., Kraft, S. L., Boyes, S. G., Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer (2009) Biomacromolecules, 10, pp. 983-993
Hong, H. -Y., Lee, H. Y., Kwak, W., Yoo, J., Na, M. -H., So, I. S., Kwon, T. -H., Lee, B. -H., Phage display selection of peptides that home to atherosclerotic plaques: IL-4 receptor as a candidate target in atherosclerosis (2008) J. Cell. Mol. Med., 12, pp. 2003-2014
Park, K., Hong, H. -Y., Moon, H. J., Lee, B. -H., Kim, I. -S., Kwon, I. C., Rhee, K., A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides (2008) J. Control. Release, 128, pp. 217-223
Wu, X. L., Kim, J. H., Koo, H., Bae, S. M., Shin, H., Kim, M. S., Lee, B. -H., Lee, D. S., Tumor-targeting peptide conjugated pH responsive micelles as a potential drug carrier for cancer therapy (2010) Bioconjugate Chem., 21, pp. 208-213
Reddy, G. R., Bhojani, M. S., McConville, P., Moody, J., Moffat, B. A., Hall, D. E., Kim, G., Ross, B. D., Vascular targeted nanoparticles for imaging and treatment of brain tumors (2006) Clin. Cancer Res., 12, pp. 6677-6686
Guthi, J. S., Yang, S. -G., Huang, G., Li, S., Khemtong, C., Kessinger, C. W., Peyton, M., Gao, J., MRI-visible micellar nanomedicine for targeted drug delivery tolung cancer cells (2010) Mol. Pharmaceutics, 7, pp. 32-40
Lyons, S. A., O'Neal, J., Sontheimer, H., Chlorotoxin a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin (2002) Glia, 39, pp. 162-173
Park, J. H., Von Maltzahn, G., Zhang, L., Schwartz, M. P., Ruoslahtim, E., Bhatia, S. N., Sailor, M. J., Magnetic iron oxide nanoworms for tumor targeting and imaging (2008) Adv. Mater., 20, pp. 1630-1715
Alivisatos, A. P., Semiconductor clusters, nanocrystals, and quantum dots (1996) Science, 271, pp. 933-937
Hu, R., Yong, K. -T., Roy, I., Ding, H., Law, W. -C., Cai, H., Zhang, X., Prasad, P. N., Functionalized near-infrared quantum dots for in vivo tumor vasculature imaging (2010) Nanotechnology, 21, p. 145105
Cheng, S. -H., Lee, C. -H., Chen, M. -C., Souris, J. S., Tseng, F. -G., Yang, C. -S., Mou, C. -Y., Lo, L. -W., Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics - The trio of imaging, targeting and therapy (2010) J. Mater. Chem., 20, pp. 6149-6157
Ashley, C. E., Carnes, E. C., Phillips, G. K., Padilla, D., Durfee, P. N., Brown, P. A., Hanna, T. N., Brinker, C. J., The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers (2011) Nature Materials, 10, pp. 389-397
Polym J (ISSN: 0032-3896), 2013 May; 45(5): 481-493.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.554, 5-year impact factor: 1.33
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84877602711&partnerID=40&md5=4a3ffbaffc4275e359658cc49ac1e867
Keywords: Doxorubicin, Liposomes, Nanosystems, Peptides, Polymeric Micelles, Theranostics, Multifunctional Compounds, Personalized Medicines, Simultaneous Imaging, Targeting Peptides, Therapeutic Modality, Diagnosis, Disease Control, Drug Therapy,
Affiliations:
*** IBB - CNR ***
Department of Biological Sciences, IBB CNR, University of Naples 'Federico II', Via Mezzocannone, 16, Napoli 80134, Italy
References:
Byrne, J.D., Betancourt, T., Brannon-Pppas, L., Active targeting schemes for nanoparticle systems in cancer therapeutics (2008) Adv. Drug Delivery Rev., 60, pp. 1615-162
Janib, S.M., Moses, A.S., MacKay, J.A., Imaging and drug delivery using theranostic nanoparticles (2010) Adv. Drug. Delivery Rev., 62, pp. 1052-1063
Smith-Jones, P.M., Bischof, C., Leimer, M., Gludovacz, D., Angelberger, P., Pangerl, T., Peck-Radosavljevic, M., Virgolini, I., DOTA-lanreotide: A novel somatostatin analog for tumor diagnosis and therapy (1999) Endocrinology, 140, pp. 5136-5148
Aloj, L., Panico, M., Caraco, C., Del Vecchio, S., Arra, C., Affuso, A., Tesauro, D., Salvatore, M., In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (2004) Journal of Nucl. Med., 45, pp. 485-494
Rogers, B.E., Bigott, H.M., McCarthy, D.W., Della Manna, D., Kim, J., Sharp, T.L., Welch, M.J., MicroPET imaging of a gastrin-releasing peptide receptor-positive tumor in a mouse model of human prostate cancer using a 64Cu-labeled bombesin analogue (2003) Bioconjug. Chem., 14, pp. 756-763
Farokhzad, O.C., Karp, J.M., Langer, R., Nanoparticle aptamer bioconjugates for cancer targeting (2006) Expert Opinion Drug Delivery, 3, pp. 311-324
Torchilin, V., Antibody-modified liposomes for cancer chemotherapy (2008) Expert Opinion on Drug Delivery, 5, pp. 1003-1025
Sofou, S., Sgouros, G., Antibody-targeted liposomes in cancer therapy and imaging (2008) Expert Opinion on Drug Delivery, 5, pp. 189-204
Wu, H., Chang, D.-K., Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy (2010) Journal of Oncology, 2010, pp. 723-798
James, J.S., Dubs, G., FDA approves new kind of lymphoma treatment (1997) AIDS Treat News, 284, pp. 2-3
Albanell, J., Baselga, J., Trastuzumab: A humanized anti-HER2 monoclonal antibody, for the treatment of breast cancer (1999) Drugs Today, 35, pp. 931-946
Ferrara, N., VEGF as a therapeutic target in cancer (2005) Oncology, 69, pp. 11-16
Van Cutsem, E., Kohne, C.H., Hitre, E., Zaluski, J., Chang Chien, C.-R., Makhson, A., D'Haens, G., Rougier, P., Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer (2009) N. Engl. J. Med., 360, pp. 1408-1417
Murdaca, G., Colombo, B.M., Puppo, F., Adalimumab for the treatment of immunemediated diseases: An update on old and recent indications (2011) Drugs of Today, 47, pp. 277-288
Wilson, D.S., Szostak, J.W., In vitro selection of functional nucleic acids (1999) Ann. Rev. Biochem., 68, pp. 611-647
Bates, P.J., Kahlon, J.B., Thomas, S.D., Trent, J.O., Miller, D.M., Antiproliferative activity of G-rich oligonucleotides correlates with protein binding (1999) J. Biol. Chem., 274, pp. 26369-26377
Bates, P.J., Laber, D.A., Miller, D.M., Thomas, S.D., Trent, J.O., Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer (2009) Exp. Mol. Pathol., 86, pp. 151-164
Mongelard, F., Bouvet, P., AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia (2010) Curr. Opin. Mol. Ther., 12, pp. 107-114
Bouchard, P.R., Hutabarat, R.M., Thompson, K.M., Discovery and development of therapeutic aptamers (2010) Annu Rev Pharmacol. Toxicol., 50, pp. 237-257
Beekman, K.W., Colevas, A.D., Cooney, K., Dipaola, R., Dunn, R.L., Gross, M., Keller, E.T., Hussain, M., Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: Scientific rationale and study design (2006) Clin. Genitourin. Cancer, 4, pp. 299-302
Wang, A.Z., Gu, F., Zhang, L., Chan, J.M., Radovic-Moreno, A., Shaikh, M.R., Farokhzad, O.C., Biofunctionalized targeted nanoparticles for therapeutic applications (2008) Expert Opin. Biol. Ther., 8, pp. 1063-1070
Ladner, R.C., Sato, A.K., Gorzelany, J., De Souza, M., Phage display-derived peptides as therapeutic alternatives to antibodies (2004) Drug Discovery Today, 9, pp. 525-529
Jarzyna, P.A., Gianella, A., Skajaa, T., Knudsen, G., Deddens, L.H., Cormode, D.P., Fayad, Z.A., Mulder, W.J.M., Multifunctional imaging nanoprobes. Wiley Interdiscip (2010) Rev. Nanomed. Nanobiotechnol., 2, pp. 138-150
Mulder, W.J., Castermans, K., Van Beijnum, J.R., Oude Egbrink, M.G., Chin, P.T., Fayad, Z.A., Lowik, C.W., Nicolay, K., Molecular imagingof tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots (2009) Angiogenesis, 12, pp. 17-24
Willmann, J.K., Van Bruggen, N., Dinkelborg, L.M., Gambhir, S.S., Molecular imaging in drug development (2008) Nat. Rev. Drug Discovery, 7, pp. 591-607
Thakare, V.S., Das, M., Jain, A.K., Patil, S., Jain, S., Carbon nanotubes in cancer theragnosis (2010) Nanomedicine, 5, pp. 1277-1301
Liu, Y., Miyoshi, H., Nakamura, M., Nanomedicine for drug delivery and imaging: A promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles (2007) Int. J. Cancer, 120, pp. 2527-2537
Williams, D.F., On the nature of biomaterials (2009) Biomaterials, 30, pp. 5897-5909
Kim, K., Kim, J.H., Park, H., Kim, Y.S., Park, K., Nam, H., Lee, S., Kwon, I.C., Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring (2010) J. Control. Release, 146, pp. 219-227
Yang, X., Hong, H., Grailer, J.J., Rowland, I.J., Javadi, A., Hurley, S.A., Xiao, Y., Gong, S., CRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging (2011) Biomaterials, 32, pp. 4151-4160
Nasongkla, N., Shuai, X.T., Ai, H., Ai, H., Weinberg, B.D., Pink, J., Boothman, D.A., Gao, J., CRGD functionalized polymer micelles for targeted doxorubicin delivery (2004) Angew. Chem. Int. Ed. Engl., 43, pp. 6323-6327
Singh, R., Lillard, J.W., Nanoparticles-based targeted drug delivery (2009) Exper. Mol. Pathol., 86, pp. 215-223
Yu, M.K., Park, J., Jon, S., Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy (2012) Theranostic, 2, pp. 3-44
Park, K., Lee, S., Kang, E., Kim, K., Choi, K., Kwon, I.C., New generation of multifunctional nanoparticles for cancer imaging and therapy (2009) Adv. Funct. Mater., 19, pp. 1553-1566
Petros, R.A., Desimone, J.M., Strategies in the design of nanoparticles for therapeutic applications (2010) Nat. Rev. Drug Discovery, 9, pp. 615-627
Greish, K., Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting (2010) Cancer Nanotechnology Methods in Molecular Biology, 624, pp. 25-37. , eds. (Stephen R. Grobmyer, B. M. M.) Springer, Univ Florida
Maeda, H., Wu, J., Sawa, T., Hori, K., Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review (2000) J. Control. Release, 65, pp. 271-284
Matsumura, Y., Maeda, H., A new concept for macromolecular therapies in cancer chemotherapy: Mechanisms of tumor tropic accumulation of proteins and the antitumor agents smancs (1986) Cancer Res., 6, pp. 6397-6392
Danhier, F., Feron, O., Preat, V., To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery (2010) J. Control. Release, 148, pp. 135-146
Lasic, D.D., Papahadjopoulos, D., (1998) Medical Applications of Liposomes, , Elsevier Science, Amsterdam
Hortobagyi, G.N., Anthracyclines in the treatment of cancer: An overview (1997) Drugs, 54, pp. 1-7
Gabizon, A., Martin, F., Polyethylene glycol-coated (pegylated) liposomal Doxorubicin: Rationale for use in solid tumors (1997) Drugs, 54, pp. 15-21
Gabizon, A., Pharmacokinetics of PEGylated liposomal Doxorubicin (2003) Clin. Pharmacokinet., 42, pp. 419-436
Abraham, S.A., Waterhouse, D.N., Lawrence, D., Cullis, P.R., Madden, T.D., Bally, M.B., The liposomal formulation of doxorubicin (2005) Methods Enzymol., 391, pp. 71-97
Murphy, E.A., Majeti, B.K., Barnes, L.A., Makale, M., Weis, S.M., Lutu-Fuga, K., Wrasidlo, W., Cheresh, D.A., Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis (2008) PNAS, 105, pp. 9343-9348
Gasparini, G., Brooks, P.C., Biganzoli, E., Vermeulen, P.B., Bonoldi, E., Dirix, L.Y., Ranieri, G., Cheresh, D.A., Vascular integrin avb3: A new prognostic indicator in breast cancer (1998) Clin. Cancer Res., 4, pp. 2625-2634
He, X., Na, M.H., Kim, J.S., Lee, G.-Y., Park, J.Y., Hoffman, A.S., Nam, J.O., Lee, B.-H., A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor (2011) Mol. Pharmaceutics, 8, pp. 430-438
Accardo, A., Morisco, A., Tesauro, D., Pedone, C., Morelli, G., Naposomes: A new class of peptide derivatized target selective multimodal nanoparticles for imaging and therapeutic applications (2011) Therapeutic Delivery, 2, pp. 235-257
Vaccaro, M., Mangiapia, G., Radulescu, A., Schille'N, K., D'Errico, G., Morelli, G., Paduano, L., Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: Physico-chemical characterization (2009) Soft Matter, 5, pp. 2504-2512
Reubi, J.C., Schaer, J.C., Waser, B., Cholecystokinin (CCK) -A and CCK-B/gastrin receptors in human tumors (1997) Cancer Res., 57, pp. 1377-1386
Dufresne, M., Seva, C., Fourmy, D., Cholecystokinin and gastrin receptors (2006) Physiol. Rev., 86, pp. 805-847
Markwalder, R., Reubi, J.C., Gastrin-releasing peptide receptors in the human prostate: Relation to neoplastic transformation (1999) Cancer Res., 59, pp. 1152-1159
Gugger, M., Reubi, J.C., Gastrin-releasing peptide receptors in non-neoplastic and neoplastic tuman breast (1999) Am. J. Pathol., 155, pp. 2067-2076
Fleischmann, A., Waser, B., Reubi, J.C., Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms (2007) Cell. Oncol., 29, pp. 421-433
Reubi, J.C., Waser, B., Schaer, J.C., Laissue, J.A., Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands (2001) Eur. J. Nucl. Med., 28, pp. 836-846
Bell, G., Reisine, T., Molecular biology of somatostatin receptors (1993) Trends Neurosci., 16, pp. 34-38
Reubi, J.C., Horisberger, U., Laissue, J., High density of somatostatin receptors in veins surrounding human cancer tissue: Role in tumor host interaction? (1994) Int. J. Cancer, 56, pp. 681-688
Accardo, A., Tesauro, D., Aloj, L., Tarallo, L., Arra, C., Mangiapia, G., Vaccaro, M., Morelli, G., Peptide containing aggregates as selective nanocarriers for therapeutics (2008) ChemMedChem, 3, pp. 594-602
Morisco, A., Accardo, A., Tesauro, D., Palumbo, R., Benedetti, E., Morelli, G., Peptidelabeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (2011) Biopolymers (Peptide Sciences), 96, pp. 88-96
Accardo, A., Salzano, G., Morisco, A., Aurilio, M., Parisi, A., Maione, F., Cicala, C., Morelli, G., Peptide modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (2012) Int. J. Nanomed., 7, pp. 2007-2017
Jones, M., Leroux, J., Polymeric micelles - A new generation of colloidal drug carriers (1999) Eur. J. Pharm. Biopharm., 48, pp. 101-111
Sutton, D., Nasongkla, N., Blanco, E., Gao, J., Functionalized micellar systems for cancer targeted drug delivery (2007) Pharm. Res., 24, pp. 1029-1046
Shuai, X., Ai, H., Nasongkla, N., Kim, S., Gao, J., Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery (2004) J. Control. Release, 98, pp. 415-426
Rowe, M.D., Thamm, D.H., Kraft, S.L., Boyes, S.G., Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer (2009) Biomacromolecules, 10, pp. 983-993
Xiao, Y., Hong, H., Javadi, A., Engle, J.W., Xu, W., Yang, Y., Zhang, Y., Gong, S., Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging (2012) Biomaterials, 33, pp. 3071-3082
Hong, H.-Y., Lee, H.Y., Kwak, W., Yoo, J., Na, M.-H., So, I.S., Kwon, T.-H., Lee, B.-H., Phage display selection of peptides that home to atherosclerotic plaques: IL-4 receptor as a candidate target in atherosclerosis (2008) J. Cell. Mol. Med., 12, pp. 2003-2014
Park, K., Hong, H.-Y., Moon, H.J., Lee, B.-H., Kim, I.-S., Kwon, I.C., Rhee, K., A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides (2008) J. Control. Release, 128, pp. 217-223
Wu, X.L., Kim, J.H., Koo, H., Bae, S.M., Shin, H., Kim, M.S., Lee, B.-H., Lee, D.S., Tumor-targeting peptide conjugated pH responsive micelles as a potential drug carrier for cancer therapy (2010) Bioconjugate Chem., 21, pp. 208-213
Christian, S., Pilch, J., Akerman, M.E., Porkka, K., Laakkonen, P., Ruoslahti, E., Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels (2003) J. Cell. Biol., 163, pp. 871-878
Reddy, G.R., Bhojani, M.S., McConville, P., Moody, J., Moffat, B.A., Hall, D.E., Kim, G., Ross, B.D., Vascular targeted nanoparticles for imaging and treatment of brain tumors (2006) Clin. Cancer Res., 12, pp. 6677-6686
Nasongkla, N., Bey, E., Ren, J., Ai, H., Khemtong, C., Guthi, J.S., Chin, S.-F., Gao, J., Multifunctional polymeric micelles as cancertargeted, MRI-ultrasensitive drug delivery systems (2006) Nano Lett., 6, pp. 2427-2430
Blanco, E., Kessinger, C.W., Sumer, B.D., Gao, J., Multifunctional micellar nanomedicine for cancer therapy (2009) Experimental Biology and Medicine, 234, pp. 123-131
Guthi, J.S., Yang, S.-G., Huang, G., Li, S., Khemtong, C., Kessinger, C.W., Peyton, M., Gao, J., MRI-visible micellar nanomedicine for targeted drug delivery tolung cancer cells (2010) Mol. Pharmaceutics, 7, pp. 32-40
Gianella, A., Jarzyna, P.A., Mani, V., Ramachandran, S., Calcagno, C., Tang, J., Kann, B., Mulder, W.J.M., Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer (2011) Nano Acs, 5, pp. 4422-4433
Simberg, D., Duza, T., Park, J.H., Essler, M., Pilch, J., Zhang, L., Derfus, A.M., Ruoslahti, E., Biomimetic amplification of nanoparticle homing to tumors (2007) PNAS, 104, pp. 932-936
Agemy, L., Sugahara, K.N., Kotamraju, V.R., Gujraty, K., Girard, O.M., Kono, Y., Mattrey, R.F., Ruoslahti, E., Nanoparticle-induced vascular blockade in human prostate cancer (2010) Blood, 116, pp. 2847-2856
Agemy, L., Friedmann-Morvinski, D., Kotamraju, V.R., Roth, L., Sugahara, K.N., Girard, O.M., Mattrey, R.F., Ruoslahti, E., Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma (2011) PNAS, 108, pp. 17450-17455
Wang, Y., Leaf, H., Multifunctional theranostic nanoparticles for brain tumors (2012) Molecular Therapy, 20, pp. 10-11
Mok, H., Veiseh, O., Fang, C., Kievit, F.M., Wang, F.Y., Park, J.O., Zhang, M., PHSensitive SiRNA nanovector for targeted gene silencing and cytotoxic effect in cancer cells (2010) Mol. Pharm., 7, pp. 1930-1939
Lyons, S.A., O'Neal, J., Sontheimer, H., Chlorotoxin a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin (2002) Glia, 39, pp. 162-173
Kumar, M., Yigit, M., Dai, G., Moore, A., Medarova, Z., Image-guided breast tumor therapy using a small interfering RNA nanodrug (2010) Cancer Res., 70, pp. 7553-7561
Von Maltzahn, G., Park, J.H., Lin, K.Y., Singh, N., Schwoppe, C., Mesters, R., Berdel, W.E., Bhatia, S.N., Nanoparticles that communicate in vivo to amplify tumor targeting (2011) Nat. Mater., 10, pp. 545-552
Park, J.H., Von Maltzahn, G., Zhang, L., Schwartz, M.P., Ruoslahtim, E., Bhatia, S.N., Sailor, M.J., Magnetic iron oxide nanoworms for tumor targeting and imaging (2008) Adv. Mater., 20, pp. 1630-1715
Alivisatos, A.P., Semiconductor clusters, nanocrystals, and quantum dots (1996) Science, 271, pp. 933-937
Bruchez, M., Moronne, M., Gin, P., Weiss, S., Alivisatos, A.P., Semiconductor nanocrystals as fluorescent biological labels (1998) Science, 281, pp. 2013-2016
Hu, R., Yong, K.-T., Roy, I., Ding, H., Law, W.-C., Cai, H., Zhang, X., Prasad, P.N., Functionalized near-infrared quantum dots for in vivo tumor vasculature imaging (2010) Nanotechnology, 21, p. 145105
Cheng, S.-H., Lee, C.-H., Chen, M.-C., Souris, J.S., Tseng, F.-G., Yang, C.-S., Mou, C.-Y., Lo, L.-W., Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics - The trio of imaging, targeting and therapy (2010) J. Mater. Chem., 20, pp. 6149-6157
Ashley, C.E., Carnes, E.C., Phillips, G.K., Padilla, D., Durfee, P.N., Brown, P.A., Hanna, T.N., Brinker, C.J., The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers (2011) Nature Materials, 10, pp. 389-397
Byrne, J. D., Betancourt, T., Brannon-Pppas, L., Active targeting schemes for nanoparticle systems in cancer therapeutics (2008) Adv. Drug Delivery Rev., 60, pp. 1615-162
Janib, S. M., Moses, A. S., MacKay, J. A., Imaging and drug delivery using theranostic nanoparticles (2010) Adv. Drug. Delivery Rev., 62, pp. 1052-1063
Smith-Jones, P. M., Bischof, C., Leimer, M., Gludovacz, D., Angelberger, P., Pangerl, T., Peck-Radosavljevic, M., Virgolini, I., DOTA-lanreotide: A novel somatostatin analog for tumor diagnosis and therapy (1999) Endocrinology, 140, pp. 5136-5148
Rogers, B. E., Bigott, H. M., McCarthy, D. W., Della Manna, D., Kim, J., Sharp, T. L., Welch, M. J., MicroPET imaging of a gastrin-releasing peptide receptor-positive tumor in a mouse model of human prostate cancer using a 64Cu-labeled bombesin analogue (2003) Bioconjug. Chem., 14, pp. 756-763
Farokhzad, O. C., Karp, J. M., Langer, R., Nanoparticle aptamer bioconjugates for cancer targeting (2006) Expert Opinion Drug Delivery, 3, pp. 311-324
Wu, H., Chang, D. -K., Peptide-mediated liposomal drug delivery system targeting tumor blood vessels in anticancer therapy (2010) Journal of Oncology, 2010, pp. 723-798
James, J. S., Dubs, G., FDA approves new kind of lymphoma treatment (1997) AIDS Treat News, 284, pp. 2-3
Wilson, D. S., Szostak, J. W., In vitro selection of functional nucleic acids (1999) Ann. Rev. Biochem., 68, pp. 611-647
Bates, P. J., Kahlon, J. B., Thomas, S. D., Trent, J. O., Miller, D. M., Antiproliferative activity of G-rich oligonucleotides correlates with protein binding (1999) J. Biol. Chem., 274, pp. 26369-26377
Bates, P. J., Laber, D. A., Miller, D. M., Thomas, S. D., Trent, J. O., Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer (2009) Exp. Mol. Pathol., 86, pp. 151-164
Bouchard, P. R., Hutabarat, R. M., Thompson, K. M., Discovery and development of therapeutic aptamers (2010) Annu Rev Pharmacol. Toxicol., 50, pp. 237-257
Beekman, K. W., Colevas, A. D., Cooney, K., Dipaola, R., Dunn, R. L., Gross, M., Keller, E. T., Hussain, M., Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: Scientific rationale and study design (2006) Clin. Genitourin. Cancer, 4, pp. 299-302
Wang, A. Z., Gu, F., Zhang, L., Chan, J. M., Radovic-Moreno, A., Shaikh, M. R., Farokhzad, O. C., Biofunctionalized targeted nanoparticles for therapeutic applications (2008) Expert Opin. Biol. Ther., 8, pp. 1063-1070
Ladner, R. C., Sato, A. K., Gorzelany, J., De Souza, M., Phage display-derived peptides as therapeutic alternatives to antibodies (2004) Drug Discovery Today, 9, pp. 525-529
Jarzyna, P. A., Gianella, A., Skajaa, T., Knudsen, G., Deddens, L. H., Cormode, D. P., Fayad, Z. A., Mulder, W. J. M., Multifunctional imaging nanoprobes. Wiley Interdiscip (2010) Rev. Nanomed. Nanobiotechnol., 2, pp. 138-150
Mulder, W. J., Castermans, K., Van Beijnum, J. R., Oude Egbrink, M. G., Chin, P. T., Fayad, Z. A., Lowik, C. W., Nicolay, K., Molecular imagingof tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots (2009) Angiogenesis, 12, pp. 17-24
Willmann, J. K., Van Bruggen, N., Dinkelborg, L. M., Gambhir, S. S., Molecular imaging in drug development (2008) Nat. Rev. Drug Discovery, 7, pp. 591-607
Thakare, V. S., Das, M., Jain, A. K., Patil, S., Jain, S., Carbon nanotubes in cancer theragnosis (2010) Nanomedicine, 5, pp. 1277-1301
Williams, D. F., On the nature of biomaterials (2009) Biomaterials, 30, pp. 5897-5909
Kim, K., Kim, J. H., Park, H., Kim, Y. S., Park, K., Nam, H., Lee, S., Kwon, I. C., Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring (2010) J. Control. Release, 146, pp. 219-227
Yu, M. K., Park, J., Jon, S., Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy (2012) Theranostic, 2, pp. 3-44
Petros, R. A., Desimone, J. M., Strategies in the design of nanoparticles for therapeutic applications (2010) Nat. Rev. Drug Discovery, 9, pp. 615-627
Lasic, D. D., Papahadjopoulos, D., (1998) Medical Applications of Liposomes, , Elsevier Science, Amsterdam
Hortobagyi, G. N., Anthracyclines in the treatment of cancer: An overview (1997) Drugs, 54, pp. 1-7
Abraham, S. A., Waterhouse, D. N., Lawrence, D., Cullis, P. R., Madden, T. D., Bally, M. B., The liposomal formulation of doxorubicin (2005) Methods Enzymol., 391, pp. 71-97
Murphy, E. A., Majeti, B. K., Barnes, L. A., Makale, M., Weis, S. M., Lutu-Fuga, K., Wrasidlo, W., Cheresh, D. A., Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis (2008) PNAS, 105, pp. 9343-9348
He, X., Na, M. H., Kim, J. S., Lee, G. -Y., Park, J. Y., Hoffman, A. S., Nam, J. O., Lee, B. -H., A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor (2011) Mol. Pharmaceutics, 8, pp. 430-438
Reubi, J. C., Schaer, J. C., Waser, B., Cholecystokinin (CCK) -A and CCK-B/gastrin receptors in human tumors (1997) Cancer Res., 57, pp. 1377-1386
Reubi, J. C., Waser, B., Schaer, J. C., Laissue, J. A., Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands (2001) Eur. J. Nucl. Med., 28, pp. 836-846
Reubi, J. C., Horisberger, U., Laissue, J., High density of somatostatin receptors in veins surrounding human cancer tissue: Role in tumor host interaction? (1994) Int. J. Cancer, 56, pp. 681-688
Rowe, M. D., Thamm, D. H., Kraft, S. L., Boyes, S. G., Polymer-modified gadolinium metal-organic framework nanoparticles used as multifunctional nanomedicines for the targeted imaging and treatment of cancer (2009) Biomacromolecules, 10, pp. 983-993
Hong, H. -Y., Lee, H. Y., Kwak, W., Yoo, J., Na, M. -H., So, I. S., Kwon, T. -H., Lee, B. -H., Phage display selection of peptides that home to atherosclerotic plaques: IL-4 receptor as a candidate target in atherosclerosis (2008) J. Cell. Mol. Med., 12, pp. 2003-2014
Park, K., Hong, H. -Y., Moon, H. J., Lee, B. -H., Kim, I. -S., Kwon, I. C., Rhee, K., A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides (2008) J. Control. Release, 128, pp. 217-223
Wu, X. L., Kim, J. H., Koo, H., Bae, S. M., Shin, H., Kim, M. S., Lee, B. -H., Lee, D. S., Tumor-targeting peptide conjugated pH responsive micelles as a potential drug carrier for cancer therapy (2010) Bioconjugate Chem., 21, pp. 208-213
Reddy, G. R., Bhojani, M. S., McConville, P., Moody, J., Moffat, B. A., Hall, D. E., Kim, G., Ross, B. D., Vascular targeted nanoparticles for imaging and treatment of brain tumors (2006) Clin. Cancer Res., 12, pp. 6677-6686
Guthi, J. S., Yang, S. -G., Huang, G., Li, S., Khemtong, C., Kessinger, C. W., Peyton, M., Gao, J., MRI-visible micellar nanomedicine for targeted drug delivery tolung cancer cells (2010) Mol. Pharmaceutics, 7, pp. 32-40
Lyons, S. A., O'Neal, J., Sontheimer, H., Chlorotoxin a scorpion-derived peptide, specifically binds to gliomas and tumors of neuroectodermal origin (2002) Glia, 39, pp. 162-173
Park, J. H., Von Maltzahn, G., Zhang, L., Schwartz, M. P., Ruoslahtim, E., Bhatia, S. N., Sailor, M. J., Magnetic iron oxide nanoworms for tumor targeting and imaging (2008) Adv. Mater., 20, pp. 1630-1715
Alivisatos, A. P., Semiconductor clusters, nanocrystals, and quantum dots (1996) Science, 271, pp. 933-937
Hu, R., Yong, K. -T., Roy, I., Ding, H., Law, W. -C., Cai, H., Zhang, X., Prasad, P. N., Functionalized near-infrared quantum dots for in vivo tumor vasculature imaging (2010) Nanotechnology, 21, p. 145105
Cheng, S. -H., Lee, C. -H., Chen, M. -C., Souris, J. S., Tseng, F. -G., Yang, C. -S., Mou, C. -Y., Lo, L. -W., Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics - The trio of imaging, targeting and therapy (2010) J. Mater. Chem., 20, pp. 6149-6157
Ashley, C. E., Carnes, E. C., Phillips, G. K., Padilla, D., Durfee, P. N., Brown, P. A., Hanna, T. N., Brinker, C. J., The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers (2011) Nature Materials, 10, pp. 389-397
Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors
Over recent years, multifunctional compounds that combine diagnostic and therapeutic modalities using one unified material have been developed and designated as theranostics. These compounds provide the chance to develop individually designed therapies against various diseases to accomplish personalized medicine. In this review, theranostic agents based on nanovectors (liposomes, naposomes, micelles, polymeric micelles and micelles built around a solid core) externally modified with targeting peptides able to simultaneously carry a drug and a contrast agent are described, demonstrating that peptide-modified nanovectors can selectively carry a drug to target cells with an imaging probe co-incorporated into the nanovector to monitor therapy. © 2013 The Society of Polymer Science, Japan (SPSJ) All rights reserved.
Over recent years, multifunctional compounds that combine diagnostic and therapeutic modalities using one unified material have been developed and designated as theranostics. These compounds provide the chance to develop individually designed therapies against various diseases to accomplish personalized medicine. In this review, theranostic agents based on nanovectors (liposomes, naposomes, micelles, polymeric micelles and micelles built around a solid core) externally modified with targeting peptides able to simultaneously carry a drug and a contrast agent are described, demonstrating that peptide-modified nanovectors can selectively carry a drug to target cells with an imaging probe co-incorporated into the nanovector to monitor therapy. © 2013 The Society of Polymer Science, Japan (SPSJ) All rights reserved.
Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors
| ▼ New synthetic molecules for active targeting of multifunctional theranostic nanosystems |
Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors
Other filter: ([btitle,keywords] "Doxorubicin" OR [bti ...
Scognamiglio PL, Riccardi C, Palumbo R, Gale TF, Musumeci D, Roviello GN
* Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems (13 views)
Journal Of Nanostructure In Chemistry, 2023 Feb; N/D: N/D-N/D.
Impact Factor: 8
View Export to BibTeX Export to EndNote
Capozza M, Anemone A, Dhakan C, Della Peruta M, Bracesco M, Zullino S, Villano D, Terreno E, Longo DL, Aime S
* GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[(18)F]F-FDG-PET (12 views)
Mol Imaging Biol (ISSN: 1536-1632linking), 2021 Aug 12; N/D: N/D-N/D.
Impact Factor:
View Export to BibTeX Export to EndNote
Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (182 views)
Antioxid Redox Signal (ISSN: 1523-0864linking, 1557-7716), 2019 Nov 20; 31 (15 ): 1166-1174.
Impact Factor: 7.581
View Export to BibTeX Export to EndNote
Gargiulo S, Albanese S, Mancini M
* State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics (207 views)
Contrast Media Mol Imaging (ISSN: 1555-4309linking, 1555-4317electronic), 2019 Apr 30; 2019: 5080267-5080267.
Impact Factor: 1.984
View Export to BibTeX Export to EndNote
Gargiulo S, Albanese S, Mancini M
* State of the art preclinical photoacoustic imaging: recent advances in cancer theranostics (181 views)
Contrast Media & Molecular Imaging, 2019; 2019: Article-Article.
Impact Factor: 2.934
View Export to BibTeX Export to EndNote
Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (464 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
View Export to BibTeX Export to EndNote
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (459 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
View Export to BibTeX Export to EndNote
Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (447 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
View Export to BibTeX Export to EndNote
Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (334 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Rizzitelli S, Giustetto P, Cutrin JC, Delli Castelli D, Boffa C, Ruzza M, Menchise V, Molinari F, Aime S, Terreno E
* Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (480 views)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Impact Factor: 7.441
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Morelli G, Galdiero M
* gH625: A milestone in understanding the many roles of membranotropic peptides (530 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Jan; 1848(PA): 16-25.
Impact Factor: 5.158
View Export to BibTeX Export to EndNote
Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (452 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (509 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
View Export to BibTeX Export to EndNote
Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (546 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (379 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (455 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
View Export to BibTeX Export to EndNote
Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (663 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
View Export to BibTeX Export to EndNote
Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY
* Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates (548 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8512-8520.
Impact Factor: 5.48
View Export to BibTeX Export to EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (467 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (410 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (397 views)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
View Export to BibTeX Export to EndNote
Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (410 views)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (493 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (383 views)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
View Export to BibTeX Export to EndNote
Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
* A versatile strategy for signal amplification based on core/shell silica nanoparticles (475 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Nov 25; 17(48): 13429-13432.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (458 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, Conson M, Torre G, Caterino M, De Rosa N, Picardi M, Camera L, Solla R, Farella A, Salvatore M, Pacelli R
* Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (470 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2011 Nov; 101(2): 316-321.
Impact Factor: 5.58
View Export to BibTeX Export to EndNote
Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (466 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (609 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
View Export to BibTeX Export to EndNote
Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (409 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (360 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
View Export to BibTeX Export to EndNote
Strianese D, Tranfa F, Finelli M, De Renzo A, Staibano S, Schiemer R, Cardone D, Pacelli R, Perna F, Mascolo M, De Rosa G, Bonavolonta G
* Hepatitis C virus infection in ocular adnexal lymphomas (369 views)
Arch Ophthalmol (ISSN: 1538-3601, 0003-9950), 2010 Oct; 128(10): 1295-1299.
Impact Factor: 3.516
View Export to BibTeX Export to EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (621 views)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
View Export to BibTeX Export to EndNote
Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP
* Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications (460 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2010 Apr 8; 5(4): N/D-N/D.
Impact Factor: 4.411
View Export to BibTeX Export to EndNote
Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
View Export to BibTeX Export to EndNote
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (618 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (991 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (617 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Mangiapia G, Pedone C, Morelli G
* Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers (429 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(2): 115-121.
Impact Factor: 2.389
View Export to BibTeX Export to EndNote
De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
View Export to BibTeX Export to EndNote
Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (247 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
View Export to BibTeX Export to EndNote
Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (468 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (277 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
View Export to BibTeX Export to EndNote
Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (468 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
View Export to BibTeX Export to EndNote
Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
View Export to BibTeX Export to EndNote
MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (330 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
View Export to BibTeX Export to EndNote
Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
* Self‑assembly of thyminyl l‑tryptophanamide (TrpT) building blocks for the potential development of drug delivery nanosystems (13 views)
Journal Of Nanostructure In Chemistry, 2023 Feb; N/D: N/D-N/D.
Impact Factor: 8
View Export to BibTeX Export to EndNote
Capozza M, Anemone A, Dhakan C, Della Peruta M, Bracesco M, Zullino S, Villano D, Terreno E, Longo DL, Aime S
* GlucoCEST MRI for the Evaluation Response to Chemotherapeutic and Metabolic Treatments in a Murine Triple-Negative Breast Cancer: A Comparison with[(18)F]F-FDG-PET (12 views)
Mol Imaging Biol (ISSN: 1536-1632linking), 2021 Aug 12; N/D: N/D-N/D.
Impact Factor:
View Export to BibTeX Export to EndNote
Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (182 views)
Antioxid Redox Signal (ISSN: 1523-0864linking, 1557-7716), 2019 Nov 20; 31 (15 ): 1166-1174.
Impact Factor: 7.581
View Export to BibTeX Export to EndNote
Gargiulo S, Albanese S, Mancini M
* State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics (207 views)
Contrast Media Mol Imaging (ISSN: 1555-4309linking, 1555-4317electronic), 2019 Apr 30; 2019: 5080267-5080267.
Impact Factor: 1.984
View Export to BibTeX Export to EndNote
Gargiulo S, Albanese S, Mancini M
* State of the art preclinical photoacoustic imaging: recent advances in cancer theranostics (181 views)
Contrast Media & Molecular Imaging, 2019; 2019: Article-Article.
Impact Factor: 2.934
View Export to BibTeX Export to EndNote
Oliveri V, Bellia F, Viale M, Maric I, Vecchio G
* Linear polymers of beta and gamma cyclodextrins with a polyglutamic acid backbone as carriers for doxorubicin (464 views)
Carbohyd Polym (ISSN: 0144-8617), 2017 Dec 1; 177: 355-360.
Impact Factor: 5.158
View Export to BibTeX Export to EndNote
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (459 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
View Export to BibTeX Export to EndNote
Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (447 views)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
View Export to BibTeX Export to EndNote
Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (334 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Rizzitelli S, Giustetto P, Cutrin JC, Delli Castelli D, Boffa C, Ruzza M, Menchise V, Molinari F, Aime S, Terreno E
* Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (480 views)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Impact Factor: 7.441
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Morelli G, Galdiero M
* gH625: A milestone in understanding the many roles of membranotropic peptides (530 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2015 Jan; 1848(PA): 16-25.
Impact Factor: 5.158
View Export to BibTeX Export to EndNote
Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (452 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
View Export to BibTeX Export to EndNote
Galdiero S, Falanga A, Vitiello M, Grieco P, Caraglia M, Morelli G, Galdiero M
* Exploitation of viral properties for intracellular delivery (509 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2014 Jul; 20(7): 468-478.
Impact Factor: 1.546
View Export to BibTeX Export to EndNote
Gallicchio R, Mansueto G, Simeon V, Nardelli A, Guariglia R, Capacchione D, Soscia E, Pedicini P, Gattozzi D, Musto P, Storto G
* F-18 FDG PET/CT quantization parameters as predictors of outcome in patients with diffuse large B-cell lymphoma (546 views)
Eur J Haematol (ISSN: 0902-4441), 2014 May; 92(5): 382-389.
Impact Factor: 2.066
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (379 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (455 views)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
View Export to BibTeX Export to EndNote
Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (663 views)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
View Export to BibTeX Export to EndNote
Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY
* Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates (548 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2013 Nov 14; 56(21): 8512-8520.
Impact Factor: 5.48
View Export to BibTeX Export to EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (467 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (410 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (397 views)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
View Export to BibTeX Export to EndNote
Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (410 views)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
View Export to BibTeX Export to EndNote
Cella L, Conson M, Caterino M, De Rosa N, Liuzzi R, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (493 views) (PDF 236 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2012 Apr 1; 82(5): 1802-1808.
Impact Factor: 4.524
View Export to BibTeX Export to EndNote
Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (383 views)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
View Export to BibTeX Export to EndNote
Rampazzo E, Bonacchi S, Genovese D, Juris R, Sgarzi M, Montalti M, Prodi L, Zaccheroni N, Tomaselli G, Gentile S, Satriano C, Rizzarelli E
* A versatile strategy for signal amplification based on core/shell silica nanoparticles (475 views)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Nov 25; 17(48): 13429-13432.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (458 views)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, Conson M, Torre G, Caterino M, De Rosa N, Picardi M, Camera L, Solla R, Farella A, Salvatore M, Pacelli R
* Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (470 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2011 Nov; 101(2): 316-321.
Impact Factor: 5.58
View Export to BibTeX Export to EndNote
Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (466 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (609 views)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
View Export to BibTeX Export to EndNote
Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (409 views)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Morisco A, Accardo A, Tesauro D, Palumbo R, Benedetti E, Morelli G
* Peptide-labeled supramolecular aggregates as selective doxorubicin carriers for delivery to tumor cells (360 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011; 96(1): 88-96.
Impact Factor: 2.87
View Export to BibTeX Export to EndNote
Strianese D, Tranfa F, Finelli M, De Renzo A, Staibano S, Schiemer R, Cardone D, Pacelli R, Perna F, Mascolo M, De Rosa G, Bonavolonta G
* Hepatitis C virus infection in ocular adnexal lymphomas (369 views)
Arch Ophthalmol (ISSN: 1538-3601, 0003-9950), 2010 Oct; 128(10): 1295-1299.
Impact Factor: 3.516
View Export to BibTeX Export to EndNote
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (621 views)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
View Export to BibTeX Export to EndNote
Kelly SE, Di Benedetto A, Greco A, Howard CM, Sollars VE, Primerano DA, Valluri JV, Claudio PP
* Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications (460 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2010 Apr 8; 5(4): N/D-N/D.
Impact Factor: 4.411
View Export to BibTeX Export to EndNote
Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (399 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
View Export to BibTeX Export to EndNote
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (618 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
View Export to BibTeX Export to EndNote
Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Stella AM
* Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (991 views)
Nature Reviews Neuroscience (ISSN: 1471-0048), 2007 Oct; 8(10): 766-775.
Impact Factor: 24.52
View Export to BibTeX Export to EndNote
Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (617 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Accardo A, Tesauro D, Mangiapia G, Pedone C, Morelli G
* Nanostructures by self-assembling peptide amphiphile as potential selective drug carriers (429 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2007; 88(2): 115-121.
Impact Factor: 2.389
View Export to BibTeX Export to EndNote
De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (233 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
View Export to BibTeX Export to EndNote
Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (247 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
View Export to BibTeX Export to EndNote
Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (468 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (277 views)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
View Export to BibTeX Export to EndNote
Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (468 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
View Export to BibTeX Export to EndNote
Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (283 views)
Anal Biochem (ISSN: 0003-2697, 1096-0309electronic, 0003-2697linking), 1996 May 1; 236(2): 338-343.
Impact Factor: 2.017
View Export to BibTeX Export to EndNote
MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (330 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
View Export to BibTeX Export to EndNote
Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (299 views)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
View Export to BibTeX Export to EndNote
Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (559 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
View Export to BibTeX Export to EndNote
48 Records (46 excluding Abstracts).
Total impact factor: 195.341 (186.432 excluding Abstracts).
Total 5 year impact factor: 193.919 (184.434 excluding Abstracts).
Total impact factor: 195.341 (186.432 excluding Abstracts).
Total 5 year impact factor: 193.919 (184.434 excluding Abstracts).
484 views. Last view on Monday 06 March 2023, 23:03:17
ibb.cnr.it
