Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu
Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu(481 views) Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
Keywords: Antineoplastic Agent, Dimethyl Sulfoxide, Drug Derivative, Hen Egg Lysozyme, Imidazolium Bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(iii), Imidazolium-Bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(iii), Organometallic Compound, Pyridine Derivative, Ruthenium, Animal, Article, Chemical Structure, Chemistry, Chicken, Metabolism, Microscopy, Protein Binding, X Ray Crystallography, X-Ray, Models, Molecular, Muramidase, Imidazolium Bis (imidazole) Dimethylsulfoxideimidazotetrachlororuthenate (iii), Imidazolium-Bis (imidazole) Dimethylsulfoxideimidazotetrachlororuthenate (iii),
Affiliations: *** IBB - CNR ***
Department of Chemical Sciences, University of Naples Federico II, Napoli, Italy
CNR Institute of Biostructures and Bioimages, Napoli, Italy
Consorzio per Lo Sviluppo Dei Sistemi A Grande Interfase, Florence, Italy
References: Not available.
Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu
The binding properties of AziRu, a ruthenium(III) complex with high antiproliferative activity, toward a hen egg white lysozyme have been investigated by X-ray crystallography and Raman microscopy. The data provide clear evidence on the mechanism of AziRu protein adduct formation and of ligand exchange in the crystal state.
Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu
No results.
Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(458 views) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 ViewExport to BibTeXExport to EndNote