Radioiodide induces apoptosis in human thyroid tissue in culture (361 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Dec; 44(3): 729-734.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.527, 5-year impact factor: 2.675
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84890797285&partnerID=40&md5=ae2ad6553b4d3501946571ffd78ea19b
Keywords: Apoptosis, Radioiodide Therapy, Thyroid, Caspase 3, Cytokeratin 18, Iodine 131, Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase, Article, Cell Count, Cell Viability, Culture Medium, Enzyme Linked Immunosorbent Assay, Human, Human Cell, Human Tissue, In Vitro Study, Priority Journal, Protein Cleavage, Thyroid Cell, Thyroid Tissue Culture, Tissue Culture Cell, Tissue Culture Technique, Cell Proliferation, Iodine Radioisotopes, Thyroid Gland, Drug Effects, Metabolism, Pharmacology, Cytology,
Affiliations:
*** IBB - CNR ***
Department of Cellular and Molecular Biology and Pathology, University Federico II, 80131 Naples, Italy
Department of Medicine and Surgery, University of Salerno, Via Allende, 84081 Baronissi Salerno, Italy
Department of Clinical Medicine and Surgery, University Federico II, 80131 Naples, Italy
National Cancer Institute, Fondazione G. Pascale, Naples, Italy
Department of Biomorphological and Functional Sciences, University of Naples Federico II, 80131 Naples, Italy
Department of Endocrinology, Research Center of Excellence AmbiSEN, University of Pisa, 56124 Pisa, Italy
References:
Bonnema, S.J., Hegedus, L., Radioiodine therapy in benign thyroid diseases: Effects, side effects, and factors affecting therapeutic outcome (2012) Endocrinol. Rev., , 10.1210/er.2012-103
Reiners, C., Hanscheid, H., Luster, M., Lassmann, M., Verburg, F.A., Radioiodine for remnant ablation and therapy of metastatic disease (2011) Nat. Rev. Endocrinol., 7 (10), pp. 589-595. , 10.1038/nrendo.2011.134 21826102 10.1038/nrendo.2011.134 1:CAS:528:DC%2BC3MXht1ajsrrK
Sawin, C.T., Becker, D.V., Radioiodine and the treatment of hyperthyroidism: The early history (1997) Thyroid, 7 (2), pp. 163-176. , 9133679 10.1089/thy.1997.7.163 1:STN:280:DyaK2s3nvFWksw%3D%3D
Wartofsky, L., Van Nostrand, D., Radioiodine treatment of well-differentiated thyroid cancer (2012) Endocrine, 42 (3), pp. 506-513. , 10.1007/s12020-012-9729-5 22733393 10.1007/s12020-012-9729-5 1:CAS:528:DC%2BC38XptFagsLk%3D
Bonnema, S.J., Fast, S., Hegedus, L., Non-surgical approach to the benign nodular goiter: New opportunities by recombinant human TSH-stimulated 131I-therapy (2012) Endocrine, 40 (3), pp. 344-353. , 10.1007/s12020-011-9542-6 10.1007/s12020-011-9542-6
Sawka, A.M., Thephamongkhol, K., Brouwers, M., Thabane, L., Browman, G., Gerstein, H.C., Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer (2004) J. Clin. Endocrinol. Metab., 89 (8), pp. 3668-3676. , 10.1210/jc.2003-03116789/8/3668 15292285 10.1210/jc.2003-031167 1:CAS:528:DC%2BD2cXmslKmsbc%3D
Vitale, M., Di Matola, T., D'Ascoli, F., Salzano, S., Bogazzi, F., Fenzi, G., Martino, E., Rossi, G., Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress (2000) Endocrinology, 141 (2), pp. 598-605. , 10650940 10.1210/en.141.2.598 1:CAS:528:DC%2BD3cXmvFCltg%3D%3D
Driessens, N., Versteyhe, S., Ghaddhab, C., Burniat, A., De Deken, X., Van Sande, J., Dumont, J.E., Corvilain, B., Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ (2009) Endocrinol. Relat. Cancer, 16 (3), pp. 845-856. , 10.1677/ERC-09-0020 10.1677/ERC-09-0020 1:CAS:528:DC%2BD1MXht1GnurnK
Amundson, S.A., Bittner, M., Meltzer, P., Trent, J., Fornace, Jr.A.J., Induction of gene expression as a monitor of exposure to ionizing radiation (2001) Radiat. Res., 156 (5 PART 2), pp. 657-661. , 11604088 10.1667/0033-7587(2001)156[0657:IOGEAA]2.0.CO
2 1:CAS:528:DC%2BD3MXosV2ks78%3D
Turgut, B., Babul, A., Ozdemir, O., Erselcan, T., Evaluation of the cell death pathway and apoptosis-stunning effect relationship after low- and high-dose I-131 administrations in rat thyroid tissue (2006) Cancer Biother. Radiopharm., 21 (4), pp. 342-351. , 10.1089/cbr.2006.21.342 16999600 10.1089/cbr.2006.21.342 1:CAS:528:DC%2BD28XhtVSgu7jI
Yang, T., Namba, H., Hara, T., Takmura, N., Nagayama, Y., Fukata, S., Ishikawa, N., Yamashita, S., P53 induced by ionizing radiation mediates DNA end-jointing activity, but not apoptosis of thyroid cells (1997) Oncogene, 14 (13), pp. 1511-1519. , 10.1038/sj.onc.1200979 9129141 10.1038/sj.onc.1200979 1:CAS:528:DyaK2sXislKmsLs%3D
Marx, K., Moka, D., Schomacker, K., Fischer, T., Gabruk-Szostak, B., Kobe, C., Dietlein, M., Schicha, H., Cell death induced by 131-I in a differentiated thyroid carcinoma cell line in vitro: Necrosis or apoptosis? (2006) Nucl. Med. Commun., 27 (4), pp. 353-358. , 10.1097/01.mnm.0000199475.08407 16531921 10.1097/01.mnm.0000199475.08407. e2
Hershman, J.M., Okunyan, A., Rivina, Y., Cannon, S., Hogen, V., Prevention of DNA double-strand breaks induced by radioiodide-(131)I in FRTL-5 thyroid cells (2011) Endocrinology, 152 (3), pp. 1130-1135. , 10.1210/en.2010-1163 21190956 10.1210/en.2010-1163 1:CAS:528: DC%2BC3MXktVGrtro%3D
Marotta, V., Guerra, A., Zatelli, M.C., Uberti, E.D., Stasi, V.D., Faggiano, A., Colao, A., Vitale, M., BRAF mutation positive papillary thyroid carcinoma is less advanced when Hashimoto's thyroiditis lymphocytic infiltration is present (2013) Clin. Endocrinol. (Oxf), , In press. doi: 10.1111/cen.12194
Mosmann, T., Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays (1983) J. Immunol. Methods, 65 (1-2), pp. 55-63. , 0022-1759(83)90303-4 6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D
Young, B.A., Baker, T.G., The ultrastructure of rat thyroid glands under experimental conditions in organ culture (1982) J. Anat., 135 (PART 2), pp. 407-412. , 7174511 1:STN:280:DyaL3s%2Fot1Chtg%3D%3D
Illario, M., Cavallo, A.L., Monaco, S., Di Vito, E., Mueller, F., Marzano, L.A., Troncone, G., Vitale, M., Fibronectin-induced proliferation in thyroid cells is mediated by αvβ3 integrin through Ras/Raf-1/MEK/ERK and calcium/CaMKII signals (2005) J. Clin. Endocrinol. Metab., 90 (5), pp. 2865-2873. , 15687337 10.1210/jc.2004-1520 1:CAS:528:DC%2BD2MXkt1Wgt7c%3D
Illario, M., Amideo, V., Casamassima, A., Andreucci, M., Di Matola, T., Miele, C., Rossi, G., Vitale, M., Integrin-dependent cell growth and survival are mediated by different signals in thyroid cells (2003) J. Clin. Endocrinol. Metab., 88 (1), pp. 260-269. , 12519863 10.1210/jc.2002-020774 1:CAS:528:DC%2BD3sXkvVCjsA%3D%3D
Di Matola, T., Mueller, F., Fenzi, G., Rossi, G., Bifulco, M., Marzano, L.A., Vitale, M., Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction (2000) J. Clin. Endocrinol. Metab., 85 (3), pp. 1188-1193. , 10720060 10.1210/jc.85.3.1188
Vitale, M., Casamassima, A., Illario, M., Bassi, V., Fenzi, G., Rossi, G., Cell-to-cell contact modulates the expression of the beta 1 family of integrins in primary cultures of thyroid cells (1995) Exp. Cell Res., 220 (1), pp. 124-129. , 7545127 10.1006/excr.1995.1298 1:CAS:528:DyaK2MXnvVCnsrs%3D
Sasaki, M.S., Advances in the biophysical and molecular bases of radiation cytogenetics (2009) Int. J. Radiat. Biol., 85 (1), pp. 26-47. , 10.1080/09553000802641185 19205983 10.1080/09553000802641185 1:CAS:528:DC%2BD1MXhslSnsrc%3D
Lowe, S.W., Cepero, E., Evan, G., Intrinsic tumour suppression (2004) Nature, 432 (7015), pp. 307-315. , 10.1038/nature03098 15549092 10.1038/nature03098 1:CAS:528: DC%2BD2cXpvVCjtLg%3D
Karin, M., Nuclear factor-kappaB in cancer development and progression (2006) Nature, 441 (7092), pp. 431-436. , 10.1038/nature04870 16724054 10.1038/nature04870 1:CAS:528: DC%2BD28XkvVyrsrw%3D
Levine, A.J., Momand, J., Finlay, C.A., The p53 tumour suppressor gene (1991) Nature, 351 (6326), pp. 453-456. , 10.1038/351453a0 2046748 10.1038/351453a0 1:CAS:528:DyaK3MXksVaku7g%3D
Nucera, C., Porrello, A., Antonello, Z.A., Mekel, M., Nehs, M.A., Giordano, T.J., Gerald, D., Parangi, S., B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression (2010) Proc. Natl. Acad. Sci. USA, 107 (23), pp. 10649-10654. , 10.1073/pnas.1004934107 20498063 10.1073/pnas.1004934107 1:CAS:528:DC%2BC3cXnvV2it78%3D
Chakravarty, D., Santos, E., Ryder, M., Knauf, J.A., Liao, X.H., West, B.L., Bollag, G., Fagin, J.A., Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation (2011) J. Clin. Invest, 121 (12), pp. 4700-4711. , 10.1172/JCI46382 22105174 10.1172/JCI46382 1:CAS:528:DC%2BC3MXhs1ShsLvJ
Vitale, M., Intratumor BRAFV600E heterogeneity and kinase inhibitors in the treatment of thyroid cancer: A call for participation (2013) Thyroid, , In press. doi: 10.1089/thy.2012.0614
Salzano, M., Russo, E., Postiglione, L., Guerra, A., Marotta, V., Esposito, S., Vitale, M., Interferon-gamma inhibits integrin-mediated adhesion to fibronectin and survival signaling in thyroid cells (2012) J. Endocrinol., 215 (3), pp. 439-444. , 10.1530/JOE-12-0335 23027608 10.1530/JOE-12-0335 1:CAS:528: DC%2BC38Xhsl2it7fO
Bonnema, S. J., Hegedus, L., Radioiodine therapy in benign thyroid diseases: Effects, side effects, and factors affecting therapeutic outcome (2012) Endocrinol. Rev., , 10. 1210/er. 2012-103
Sawin, C. T., Becker, D. V., Radioiodine and the treatment of hyperthyroidism: The early history (1997) Thyroid, 7 (2), pp. 163-176. , 9133679 10. 1089/thy. 1997. 7. 163 1: STN: 280: DyaK2s3nvFWksw%3D%3D
Bonnema, S. J., Fast, S., Hegedus, L., Non-surgical approach to the benign nodular goiter: New opportunities by recombinant human TSH-stimulated 131I-therapy (2012) Endocrine, 40 (3), pp. 344-353. , 10. 1007/s12020-011-9542-6 10. 1007/s12020-011-9542-6
Sawka, A. M., Thephamongkhol, K., Brouwers, M., Thabane, L., Browman, G., Gerstein, H. C., Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer (2004) J. Clin. Endocrinol. Metab., 89 (8), pp. 3668-3676. , 10. 1210/jc. 2003-03116789/8/3668 15292285 10. 1210/jc. 2003-031167 1: CAS: 528: DC%2BD2cXmslKmsbc%3D
Amundson, S. A., Bittner, M., Meltzer, P., Trent, J., Fornace, Jr. A. J., Induction of gene expression as a monitor of exposure to ionizing radiation (2001) Radiat. Res., 156 (5 PART 2), pp. 657-661. , 11604088 10. 1667/0033-7587 (2001) 156 [0657: IOGEAA] 2. 0. CO
2 1: CAS: 528: DC%2BD3MXosV2ks78%3D
Hershman, J. M., Okunyan, A., Rivina, Y., Cannon, S., Hogen, V., Prevention of DNA double-strand breaks induced by radioiodide- (131) I in FRTL-5 thyroid cells (2011) Endocrinology, 152 (3), pp. 1130-1135. , 10. 1210/en. 2010-1163 21190956 10. 1210/en. 2010-1163 1: CAS: 528: DC%2BC3MXktVGrtro%3D
Young, B. A., Baker, T. G., The ultrastructure of rat thyroid glands under experimental conditions in organ culture (1982) J. Anat., 135 (PART 2), pp. 407-412. , 7174511 1: STN: 280: DyaL3s%2Fot1Chtg%3D%3D
Sasaki, M. S., Advances in the biophysical and molecular bases of radiation cytogenetics (2009) Int. J. Radiat. Biol., 85 (1), pp. 26-47. , 10. 1080/09553000802641185 19205983 10. 1080/09553000802641185 1: CAS: 528: DC%2BD1MXhslSnsrc%3D
Lowe, S. W., Cepero, E., Evan, G., Intrinsic tumour suppression (2004) Nature, 432 (7015), pp. 307-315. , 10. 1038/nature03098 15549092 10. 1038/nature03098 1: CAS: 528: DC%2BD2cXpvVCjtLg%3D
Levine, A. J., Momand, J., Finlay, C. A., The p53 tumour suppressor gene (1991) Nature, 351 (6326), pp. 453-456. , 10. 1038/351453a0 2046748 10. 1038/351453a0 1: CAS: 528: DyaK3MXksVaku7g%3D
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Dec; 44(3): 729-734.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 3.527, 5-year impact factor: 2.675
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84890797285&partnerID=40&md5=ae2ad6553b4d3501946571ffd78ea19b
Keywords: Apoptosis, Radioiodide Therapy, Thyroid, Caspase 3, Cytokeratin 18, Iodine 131, Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase, Article, Cell Count, Cell Viability, Culture Medium, Enzyme Linked Immunosorbent Assay, Human, Human Cell, Human Tissue, In Vitro Study, Priority Journal, Protein Cleavage, Thyroid Cell, Thyroid Tissue Culture, Tissue Culture Cell, Tissue Culture Technique, Cell Proliferation, Iodine Radioisotopes, Thyroid Gland, Drug Effects, Metabolism, Pharmacology, Cytology,
Affiliations:
*** IBB - CNR ***
Department of Cellular and Molecular Biology and Pathology, University Federico II, 80131 Naples, Italy
Department of Medicine and Surgery, University of Salerno, Via Allende, 84081 Baronissi Salerno, Italy
Department of Clinical Medicine and Surgery, University Federico II, 80131 Naples, Italy
National Cancer Institute, Fondazione G. Pascale, Naples, Italy
Department of Biomorphological and Functional Sciences, University of Naples Federico II, 80131 Naples, Italy
Department of Endocrinology, Research Center of Excellence AmbiSEN, University of Pisa, 56124 Pisa, Italy
References:
Bonnema, S.J., Hegedus, L., Radioiodine therapy in benign thyroid diseases: Effects, side effects, and factors affecting therapeutic outcome (2012) Endocrinol. Rev., , 10.1210/er.2012-103
Reiners, C., Hanscheid, H., Luster, M., Lassmann, M., Verburg, F.A., Radioiodine for remnant ablation and therapy of metastatic disease (2011) Nat. Rev. Endocrinol., 7 (10), pp. 589-595. , 10.1038/nrendo.2011.134 21826102 10.1038/nrendo.2011.134 1:CAS:528:DC%2BC3MXht1ajsrrK
Sawin, C.T., Becker, D.V., Radioiodine and the treatment of hyperthyroidism: The early history (1997) Thyroid, 7 (2), pp. 163-176. , 9133679 10.1089/thy.1997.7.163 1:STN:280:DyaK2s3nvFWksw%3D%3D
Wartofsky, L., Van Nostrand, D., Radioiodine treatment of well-differentiated thyroid cancer (2012) Endocrine, 42 (3), pp. 506-513. , 10.1007/s12020-012-9729-5 22733393 10.1007/s12020-012-9729-5 1:CAS:528:DC%2BC38XptFagsLk%3D
Bonnema, S.J., Fast, S., Hegedus, L., Non-surgical approach to the benign nodular goiter: New opportunities by recombinant human TSH-stimulated 131I-therapy (2012) Endocrine, 40 (3), pp. 344-353. , 10.1007/s12020-011-9542-6 10.1007/s12020-011-9542-6
Sawka, A.M., Thephamongkhol, K., Brouwers, M., Thabane, L., Browman, G., Gerstein, H.C., Clinical review 170: A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer (2004) J. Clin. Endocrinol. Metab., 89 (8), pp. 3668-3676. , 10.1210/jc.2003-03116789/8/3668 15292285 10.1210/jc.2003-031167 1:CAS:528:DC%2BD2cXmslKmsbc%3D
Vitale, M., Di Matola, T., D'Ascoli, F., Salzano, S., Bogazzi, F., Fenzi, G., Martino, E., Rossi, G., Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress (2000) Endocrinology, 141 (2), pp. 598-605. , 10650940 10.1210/en.141.2.598 1:CAS:528:DC%2BD3cXmvFCltg%3D%3D
Driessens, N., Versteyhe, S., Ghaddhab, C., Burniat, A., De Deken, X., Van Sande, J., Dumont, J.E., Corvilain, B., Hydrogen peroxide induces DNA single- and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ (2009) Endocrinol. Relat. Cancer, 16 (3), pp. 845-856. , 10.1677/ERC-09-0020 10.1677/ERC-09-0020 1:CAS:528:DC%2BD1MXht1GnurnK
Amundson, S.A., Bittner, M., Meltzer, P., Trent, J., Fornace, Jr.A.J., Induction of gene expression as a monitor of exposure to ionizing radiation (2001) Radiat. Res., 156 (5 PART 2), pp. 657-661. , 11604088 10.1667/0033-7587(2001)156[0657:IOGEAA]2.0.CO
2 1:CAS:528:DC%2BD3MXosV2ks78%3D
Turgut, B., Babul, A., Ozdemir, O., Erselcan, T., Evaluation of the cell death pathway and apoptosis-stunning effect relationship after low- and high-dose I-131 administrations in rat thyroid tissue (2006) Cancer Biother. Radiopharm., 21 (4), pp. 342-351. , 10.1089/cbr.2006.21.342 16999600 10.1089/cbr.2006.21.342 1:CAS:528:DC%2BD28XhtVSgu7jI
Yang, T., Namba, H., Hara, T., Takmura, N., Nagayama, Y., Fukata, S., Ishikawa, N., Yamashita, S., P53 induced by ionizing radiation mediates DNA end-jointing activity, but not apoptosis of thyroid cells (1997) Oncogene, 14 (13), pp. 1511-1519. , 10.1038/sj.onc.1200979 9129141 10.1038/sj.onc.1200979 1:CAS:528:DyaK2sXislKmsLs%3D
Marx, K., Moka, D., Schomacker, K., Fischer, T., Gabruk-Szostak, B., Kobe, C., Dietlein, M., Schicha, H., Cell death induced by 131-I in a differentiated thyroid carcinoma cell line in vitro: Necrosis or apoptosis? (2006) Nucl. Med. Commun., 27 (4), pp. 353-358. , 10.1097/01.mnm.0000199475.08407 16531921 10.1097/01.mnm.0000199475.08407. e2
Hershman, J.M., Okunyan, A., Rivina, Y., Cannon, S., Hogen, V., Prevention of DNA double-strand breaks induced by radioiodide-(131)I in FRTL-5 thyroid cells (2011) Endocrinology, 152 (3), pp. 1130-1135. , 10.1210/en.2010-1163 21190956 10.1210/en.2010-1163 1:CAS:528: DC%2BC3MXktVGrtro%3D
Marotta, V., Guerra, A., Zatelli, M.C., Uberti, E.D., Stasi, V.D., Faggiano, A., Colao, A., Vitale, M., BRAF mutation positive papillary thyroid carcinoma is less advanced when Hashimoto's thyroiditis lymphocytic infiltration is present (2013) Clin. Endocrinol. (Oxf), , In press. doi: 10.1111/cen.12194
Mosmann, T., Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays (1983) J. Immunol. Methods, 65 (1-2), pp. 55-63. , 0022-1759(83)90303-4 6606682 10.1016/0022-1759(83)90303-4 1:STN:280:DyaL2c%2FovFSmtw%3D%3D
Young, B.A., Baker, T.G., The ultrastructure of rat thyroid glands under experimental conditions in organ culture (1982) J. Anat., 135 (PART 2), pp. 407-412. , 7174511 1:STN:280:DyaL3s%2Fot1Chtg%3D%3D
Illario, M., Cavallo, A.L., Monaco, S., Di Vito, E., Mueller, F., Marzano, L.A., Troncone, G., Vitale, M., Fibronectin-induced proliferation in thyroid cells is mediated by αvβ3 integrin through Ras/Raf-1/MEK/ERK and calcium/CaMKII signals (2005) J. Clin. Endocrinol. Metab., 90 (5), pp. 2865-2873. , 15687337 10.1210/jc.2004-1520 1:CAS:528:DC%2BD2MXkt1Wgt7c%3D
Illario, M., Amideo, V., Casamassima, A., Andreucci, M., Di Matola, T., Miele, C., Rossi, G., Vitale, M., Integrin-dependent cell growth and survival are mediated by different signals in thyroid cells (2003) J. Clin. Endocrinol. Metab., 88 (1), pp. 260-269. , 12519863 10.1210/jc.2002-020774 1:CAS:528:DC%2BD3sXkvVCjsA%3D%3D
Di Matola, T., Mueller, F., Fenzi, G., Rossi, G., Bifulco, M., Marzano, L.A., Vitale, M., Serum withdrawal-induced apoptosis in thyroid cells is caused by loss of fibronectin-integrin interaction (2000) J. Clin. Endocrinol. Metab., 85 (3), pp. 1188-1193. , 10720060 10.1210/jc.85.3.1188
Vitale, M., Casamassima, A., Illario, M., Bassi, V., Fenzi, G., Rossi, G., Cell-to-cell contact modulates the expression of the beta 1 family of integrins in primary cultures of thyroid cells (1995) Exp. Cell Res., 220 (1), pp. 124-129. , 7545127 10.1006/excr.1995.1298 1:CAS:528:DyaK2MXnvVCnsrs%3D
Sasaki, M.S., Advances in the biophysical and molecular bases of radiation cytogenetics (2009) Int. J. Radiat. Biol., 85 (1), pp. 26-47. , 10.1080/09553000802641185 19205983 10.1080/09553000802641185 1:CAS:528:DC%2BD1MXhslSnsrc%3D
Lowe, S.W., Cepero, E., Evan, G., Intrinsic tumour suppression (2004) Nature, 432 (7015), pp. 307-315. , 10.1038/nature03098 15549092 10.1038/nature03098 1:CAS:528: DC%2BD2cXpvVCjtLg%3D
Karin, M., Nuclear factor-kappaB in cancer development and progression (2006) Nature, 441 (7092), pp. 431-436. , 10.1038/nature04870 16724054 10.1038/nature04870 1:CAS:528: DC%2BD28XkvVyrsrw%3D
Levine, A.J., Momand, J., Finlay, C.A., The p53 tumour suppressor gene (1991) Nature, 351 (6326), pp. 453-456. , 10.1038/351453a0 2046748 10.1038/351453a0 1:CAS:528:DyaK3MXksVaku7g%3D
Nucera, C., Porrello, A., Antonello, Z.A., Mekel, M., Nehs, M.A., Giordano, T.J., Gerald, D., Parangi, S., B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression (2010) Proc. Natl. Acad. Sci. USA, 107 (23), pp. 10649-10654. , 10.1073/pnas.1004934107 20498063 10.1073/pnas.1004934107 1:CAS:528:DC%2BC3cXnvV2it78%3D
Chakravarty, D., Santos, E., Ryder, M., Knauf, J.A., Liao, X.H., West, B.L., Bollag, G., Fagin, J.A., Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation (2011) J. Clin. Invest, 121 (12), pp. 4700-4711. , 10.1172/JCI46382 22105174 10.1172/JCI46382 1:CAS:528:DC%2BC3MXhs1ShsLvJ
Vitale, M., Intratumor BRAFV600E heterogeneity and kinase inhibitors in the treatment of thyroid cancer: A call for participation (2013) Thyroid, , In press. doi: 10.1089/thy.2012.0614
Salzano, M., Russo, E., Postiglione, L., Guerra, A., Marotta, V., Esposito, S., Vitale, M., Interferon-gamma inhibits integrin-mediated adhesion to fibronectin and survival signaling in thyroid cells (2012) J. Endocrinol., 215 (3), pp. 439-444. , 10.1530/JOE-12-0335 23027608 10.1530/JOE-12-0335 1:CAS:528: DC%2BC38Xhsl2it7fO
Bonnema, S. J., Hegedus, L., Radioiodine therapy in benign thyroid diseases: Effects, side effects, and factors affecting therapeutic outcome (2012) Endocrinol. Rev., , 10. 1210/er. 2012-103
Sawin, C. T., Becker, D. V., Radioiodine and the treatment of hyperthyroidism: The early history (1997) Thyroid, 7 (2), pp. 163-176. , 9133679 10. 1089/thy. 1997. 7. 163 1: STN: 280: DyaK2s3nvFWksw%3D%3D
Bonnema, S. J., Fast, S., Hegedus, L., Non-surgical approach to the benign nodular goiter: New opportunities by recombinant human TSH-stimulated 131I-therapy (2012) Endocrine, 40 (3), pp. 344-353. , 10. 1007/s12020-011-9542-6 10. 1007/s12020-011-9542-6
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Radioiodide induces apoptosis in human thyroid tissue in culture
Radioiodide ((131)I) is routinely used for the treatment of toxic adenoma, Graves' disease, and for ablation of thyroid remnant after thyroidectomy in patients with thyroid cancer. The toxic effects of ionizing radiations on living cells can be mediated by a necrotic and/or apoptotic process. The involvement of apoptosis in radiation-induced cell death in the thyrocytes has been questioned. The knowledge of the mechanisms that underlie the thyrocyte death in response to radiations can help to achieve a successful treatment with the lowest (131)I dose. We developed a method to study the effects of (131)I in human thyroid tissue in culture, by which we demonstrated that (131)I induces thyroid cell apoptosis. Human thyroid tissues of about 1 mm(3) were cultured in vitro and cell viability was determined up to 3 weeks by the MTT assay. Radioiodide added to the culture medium was actively taken up by the tissues. The occurrence of apoptosis in the thyrocytes was assessed by measuring the production of a caspase-cleavage fragment of cytokeratin 18 (M30) by an enzyme-linked immunoassay. Neither variation of cell number nor spontaneous apoptosis was revealed after 1 week of culture. (131)I added to the culture medium induced a dose-dependent and a time-dependent generation of M30 fragment. The apoptotic process was confirmed by the generation of caspase-3 and PARP cleavage products. These results demonstrate that (131)I induces apoptosis in human thyrocytes. Human thyroid tissue cultures may be useful to investigate the cell death pathways induced by (131)I.
Radioiodide ((131)I) is routinely used for the treatment of toxic adenoma, Graves' disease, and for ablation of thyroid remnant after thyroidectomy in patients with thyroid cancer. The toxic effects of ionizing radiations on living cells can be mediated by a necrotic and/or apoptotic process. The involvement of apoptosis in radiation-induced cell death in the thyrocytes has been questioned. The knowledge of the mechanisms that underlie the thyrocyte death in response to radiations can help to achieve a successful treatment with the lowest (131)I dose. We developed a method to study the effects of (131)I in human thyroid tissue in culture, by which we demonstrated that (131)I induces thyroid cell apoptosis. Human thyroid tissues of about 1 mm(3) were cultured in vitro and cell viability was determined up to 3 weeks by the MTT assay. Radioiodide added to the culture medium was actively taken up by the tissues. The occurrence of apoptosis in the thyrocytes was assessed by measuring the production of a caspase-cleavage fragment of cytokeratin 18 (M30) by an enzyme-linked immunoassay. Neither variation of cell number nor spontaneous apoptosis was revealed after 1 week of culture. (131)I added to the culture medium induced a dose-dependent and a time-dependent generation of M30 fragment. The apoptotic process was confirmed by the generation of caspase-3 and PARP cleavage products. These results demonstrate that (131)I induces apoptosis in human thyrocytes. Human thyroid tissue cultures may be useful to investigate the cell death pathways induced by (131)I.
Radioiodide induces apoptosis in human thyroid tissue in culture
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Radioiodide induces apoptosis in human thyroid tissue in culture
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Russo M, Malandrino P, Moleti M, Vermiglio F, D'Angelo A, La Rosa G, Sapuppo G, Calaciura F, Regalbuto C, Belfiore A, Vigneri R, Pellegriti G
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Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
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Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
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Impact Factor: 4.278
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Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
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Scalia M, Satriano C, Greca R, Stella AM, Rizzarelli E, Spina-Purrello V
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
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Maurea S, Imbriaco M, Mollica C, Pace L, Salvatore M
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Impact Factor: 1.404
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Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
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Palmieri C, Falcone C, Iaccino E, Tuccillo FM, Gaspari M, Trimboli F, De Laurentiis A, Luberto L, Pontoriero M, Pisano A, Vecchio E, Fierro O, Panico M, Larobina M, Gargiulo S, Costa N, Dal Piaz F, Schiavone M, Arra C, Giudice A, Palma G, Barbieri A, Quinto I, Scala G
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Pace L, Nicolai E, Klain M, Salvatore M
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Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A
* Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice (424 views)
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Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (367 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
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Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2008 Mar; 113(2): 278-288.
Impact Factor: 0.955
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Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C
* Protective effect of orally administered carnosine on bleomycin-induced lung injury (575 views)
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Impact Factor: 4.214
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Pace L, Klain M, Albanese C, Salvatore B, Storto G, Soricelli A, Salvatore M
* Short-term outcome of differentiated thyroid cancer patients receiving a second iodine-131 therapy on the basis of a detectable serum thyroglobulin level after initial treatment (396 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Feb; 33(2): 179-183.
Impact Factor: 4.041
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Di Pietro C, Piro S, Tabbì G, Ragusa M, Di Pietro V, Zimmitti V, Cuda F, Anello M, Consoli U, Salinaro ET, Caruso M, Vancheri C, Crimi N, Sabini MG, Cirrone GA, Raffaele L, Privitera G, Pulvirenti A, Giugno R, Ferro A, Cuttone G, Lo Nigro S, Purrello R, Purrello F, Purrello M
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Impact Factor: 3.421
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Calafiore M, Battaglia G, Zappal A, Trovato-Salinaro E, Caraci F, Caruso M, Vancheri C, Sortino MA, Nicoletti F, Copani A
* Progenitor cells from the adult mouse brain acquire a neuronal phenotype in response to β-amyloid (544 views)
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Impact Factor: 5.599
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Marrazzo A, Caraci F, Salinaro ET, Su TP, Copani A, Ronsisvalle G
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Neuroreport (ISSN: 0959-4965), 2005 Sep 1; 16(11): 1223-1226.
Impact Factor: 1.995
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Pace L, Klain M, Soricelli A, Albanese C, Salvatore B, Storto G, Salvatore M
* Short Term Outcome of Differentiated Thyroid Cancer Patients with Detectable Serum Thyroglobulin after Initial Treatment Receiving a Second 131-IODINE Therapy (334 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: 179-183.
Impact Factor: 3.883
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Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (350 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
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Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (384 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
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Klain M, Maurea S, Lastoria S, Cuocolo A, Colao A, Salvatore M
Technetium-99m-tetrofosmin imaging of differentiated mixed thyroid cancer (282 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Dec; 36(12): 2248-2251.
Impact Factor: 3.491
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Lakshmanan M, Reynolds JC, Del Vecchio S, Merino MJ, Norton JA, Robbins J
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Camera L, Del Vecchio S, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Evaluation of therapeutic response using iodine-131-B72. 3 monoclonal antibody in patients with ovarian carcinoma (463 views)
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Salvati AM, d'Onofrio G, Berti P, Cappabianca MP, Marsili G, De Philippis C, Cossa L, Quarantelli M, Zini G, Mango G
An assessment of the operating characteristics of Coulter Counter model S-Plus STKR (585 views)
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Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (405 views)
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Impact Factor: 1.042
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Del Vecchio S, Mansi L, Petrillo A, Camera L, Sofia M, Marra A, Carratú L, Salvatore M
Endobronchial administration of iodine-131 B72. 3 monoclonal antibody in patients with lung cancer (292 views)
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Impact Factor: 2.692
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Del Vecchio S, Reynolds JC, Carrasquillo JA, Blasberg RG, Neumann RD, Lotze MT, Bryant GJ, Farkas RJ, Larson SM
Local distribution and concentration of intravenously injected 131I-9. 2. 27 monoclonal antibody in human malignant melanoma (350 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1989; 49(10): 2783-2789.
Impact Factor: 8.426
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* Differentiated thyroid cancer in children: Heterogeneity of predictive risk factors (288 views)
Pediatr Blood Cancer (ISSN: 1545-5009linking), 2018 Sep; 65(9): e27226-e27226.
Impact Factor: 2.513
View Export to BibTeX Export to EndNote
Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
* Prognostic Role of 18F-FDG PET/CT in the Postoperative Evaluation of Differentiated Thyroid Cancer Patients (406 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Feb; 40(2): 111-115.
Impact Factor: 4.278
View Export to BibTeX Export to EndNote
Pace L, Klain M, Salvatore B, Nicolai E, Zampella E, Assante R, Pellegrino T, Storto G, Fonti R, Salvatore M
* Prognostic Role Of 18f-Fluorodeoxyglucose Positron Emission Tomography/Ct In The Postoperative Evaluation Of Differentiated Thyroid Cancer Patients (264 views)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 2015 Feb; 40(2): 111-115.
Impact Factor: 4.278
View Export to BibTeX Export to EndNote
Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
* Should patients with remnants from thyroid microcarcinoma really not be treated with iodine-131 ablation? (430 views)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Oct; 44(2): 426-433.
Impact Factor: 3.527
View Export to BibTeX Export to EndNote
Scalia M, Satriano C, Greca R, Stella AM, Rizzarelli E, Spina-Purrello V
* PARP-1 inhibitors DPQ and PJ-34 negatively modulate proinflammatory commitment of human glioblastoma cells (422 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2013 Jan; 38(1): 50-58.
Impact Factor: 2.551
View Export to BibTeX Export to EndNote
Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (510 views)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
View Export to BibTeX Export to EndNote
Maurea S, Imbriaco M, Mollica C, Pace L, Salvatore M
* Quantitative Imaging Characterization Of Hypersecreting Or Non-Hypersecreting Adrenal Adenomas: Comparison Between Iodine-131 Nor-Cholesterol Uptake And Magnetic Resonance Signal Intensity Ratios (284 views)
Nuclear Medicine Communications (ISSN: 1473-5628, 0143-3636), 2011 Jun; 32(6): 535-541.
Impact Factor: 1.404
View Export to BibTeX Export to EndNote
Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (429 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2010 Dec; 35(12): 2144-2153.
Impact Factor: 2.608
View Export to BibTeX Export to EndNote
Palmieri C, Falcone C, Iaccino E, Tuccillo FM, Gaspari M, Trimboli F, De Laurentiis A, Luberto L, Pontoriero M, Pisano A, Vecchio E, Fierro O, Panico M, Larobina M, Gargiulo S, Costa N, Dal Piaz F, Schiavone M, Arra C, Giudice A, Palma G, Barbieri A, Quinto I, Scala G
* In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder (597 views)
Blood (ISSN: 0006-4971, 0006-6497, 0390-6078), 2010 Jul 15; 116(2): 226-238.
Impact Factor: 10.558
View Export to BibTeX Export to EndNote
Pace L, Nicolai E, Klain M, Salvatore M
* Diagnostic value of FDG PET/CT imaging (354 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009; 53(5): 503-512.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A
* Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice (424 views)
Neuropharm (ISSN: 0028-3908, 1873-7064electronic, 0028-3908linking), 2008 Sep; 55(4): 560-567.
Impact Factor: 3.383
View Export to BibTeX Export to EndNote
Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (367 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (299 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2008 Mar; 113(2): 278-288.
Impact Factor: 0.955
View Export to BibTeX Export to EndNote
Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C
* Protective effect of orally administered carnosine on bleomycin-induced lung injury (575 views)
Am J Physiol Lung Cell Mol Physiol (ISSN: 1040-0605), 2007 May; 292(5): L1095-L1095.
Impact Factor: 4.214
View Export to BibTeX Export to EndNote
Pace L, Klain M, Albanese C, Salvatore B, Storto G, Soricelli A, Salvatore M
* Short-term outcome of differentiated thyroid cancer patients receiving a second iodine-131 therapy on the basis of a detectable serum thyroglobulin level after initial treatment (396 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Feb; 33(2): 179-183.
Impact Factor: 4.041
View Export to BibTeX Export to EndNote
Di Pietro C, Piro S, Tabbì G, Ragusa M, Di Pietro V, Zimmitti V, Cuda F, Anello M, Consoli U, Salinaro ET, Caruso M, Vancheri C, Crimi N, Sabini MG, Cirrone GA, Raffaele L, Privitera G, Pulvirenti A, Giugno R, Ferro A, Cuttone G, Lo Nigro S, Purrello R, Purrello F, Purrello M
* Cellular and molecular effects of protons: Apoptosis induction and potential implications for cancer therapy (520 views)
Apoptosis (ISSN: 1360-8185), 2006 Jan; 11(1): 57-66.
Impact Factor: 3.421
View Export to BibTeX Export to EndNote
Calafiore M, Battaglia G, Zappal A, Trovato-Salinaro E, Caraci F, Caruso M, Vancheri C, Sortino MA, Nicoletti F, Copani A
* Progenitor cells from the adult mouse brain acquire a neuronal phenotype in response to β-amyloid (544 views)
Neurobiol Aging (ISSN: 0197-4580, 1558-1497electronic, 0197-4580linking), 2006; 27(4): 606-613.
Impact Factor: 5.599
View Export to BibTeX Export to EndNote
Marrazzo A, Caraci F, Salinaro ET, Su TP, Copani A, Ronsisvalle G
* Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity (584 views)
Neuroreport (ISSN: 0959-4965), 2005 Sep 1; 16(11): 1223-1226.
Impact Factor: 1.995
View Export to BibTeX Export to EndNote
Pace L, Klain M, Soricelli A, Albanese C, Salvatore B, Storto G, Salvatore M
* Short Term Outcome of Differentiated Thyroid Cancer Patients with Detectable Serum Thyroglobulin after Initial Treatment Receiving a Second 131-IODINE Therapy (334 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: 179-183.
Impact Factor: 3.883
View Export to BibTeX Export to EndNote
Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (350 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
View Export to BibTeX Export to EndNote
Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (384 views)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
View Export to BibTeX Export to EndNote
Klain M, Maurea S, Lastoria S, Cuocolo A, Colao A, Salvatore M
Technetium-99m-tetrofosmin imaging of differentiated mixed thyroid cancer (282 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Dec; 36(12): 2248-2251.
Impact Factor: 3.491
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Lakshmanan M, Reynolds JC, Del Vecchio S, Merino MJ, Norton JA, Robbins J
PELVIC RADIOIODINE UPTAKE IN A RECTAL WALL TERATOMA AFTER THYROIDECTOMY FOR PAPILLARY CARCINOMA (296 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1992 Oct; 33(10): 1848-1850.
Impact Factor: 3.491
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Camera L, Del Vecchio S, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Evaluation of therapeutic response using iodine-131-B72. 3 monoclonal antibody in patients with ovarian carcinoma (463 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991 Apr; 18(4): 269-273.
Impact Factor: 2.692
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Salvati AM, d'Onofrio G, Berti P, Cappabianca MP, Marsili G, De Philippis C, Cossa L, Quarantelli M, Zini G, Mango G
An assessment of the operating characteristics of Coulter Counter model S-Plus STKR (585 views)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 1991 Mar; 76(2): 94-103.
Impact Factor: 2.56
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Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (405 views)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1991; 18(1): 85-87.
Impact Factor: 1.042
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Del Vecchio S, Mansi L, Petrillo A, Camera L, Sofia M, Marra A, Carratú L, Salvatore M
Endobronchial administration of iodine-131 B72. 3 monoclonal antibody in patients with lung cancer (292 views)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991; 18(2): 129-132.
Impact Factor: 2.692
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Del Vecchio S, Reynolds JC, Carrasquillo JA, Blasberg RG, Neumann RD, Lotze MT, Bryant GJ, Farkas RJ, Larson SM
Local distribution and concentration of intravenously injected 131I-9. 2. 27 monoclonal antibody in human malignant melanoma (350 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1989; 49(10): 2783-2789.
Impact Factor: 8.426
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28 Records (27 excluding Abstracts).
Total impact factor: 97.257 (93.043 excluding Abstracts).
Total 5 year impact factor: 99.939 (95.681 excluding Abstracts).
Total impact factor: 97.257 (93.043 excluding Abstracts).
Total 5 year impact factor: 99.939 (95.681 excluding Abstracts).
361 views. Last view on Wednesday 01 February 2023, 6:21:57
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