Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress (562 views)
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2014 Jan 16; 5(1): e993-e993.
Export to BibTeX Export to EndNote
Paper type: Abstract, Conference, Research Support, Non-U. S. Gov'T,
Impact factor: 5.014, 5-year impact factor: 5.291
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84891783666&partnerID=40&md5=a53c824ae1c04cb0100246b242c5ca34
Keywords: Aif Cypa Complex, Mitochondria, Neuronal Death, Oxidative Stress, Peptide Inhibitor, Apoptosis Inducing Factor, Calcium Ion, Cyclophilin A, Glutamic Acid, Small Interfering Rna, Article, Cell Survival, Complex Formation, Controlled Study, In Vitro Study, Intracellular Signaling, Mitochondrial Membrane Potential, Nerve Cell Necrosis, Neuroprotection, Priority Journal, Protein Binding, Protein Expression, Protein Protein Interaction, Protein Secretion, Protein Transport, Amino Acid Motifs, Down-Regulation, Humans, Apoptosis Inducing Factor Chemistry Genetics Metabolism, Cyclophilin A Genetics Metabolism, Mitochondria Enzymology Metabolism, Neurons Cytology Enzymology Metabolism,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging (IBB), CNR, CIRPEB, Via Mezzocannone, 16, Naples 80134, Italy
Institute of Pharmacology and Clinical Pharmacy, Philipps University of Marburg, Karl-von-Frisch-Straße 1, Marburg 35032, Germany
Department of Neurodegeneration, Royal College of Surgeons in Ireland, Dublin 2, Ireland
Institute for Stroke and Dementia Research (ISD), University of Munich Medical School-Campus Großhadern, Max-Lebsche Platz 30, Munich 81377, Germany
1] Institute of Biostructures and Bioimaging (IBB)-CNR, CIRPEB, Via Mezzocannone, 16, Naples 80134, Italy [2] Institute of Pharmacology and Clinical Pharmacy, Philipps University of Marburg, Marburg 35032, Germany [3] Department of Neurodegeneration, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
1] Department of Neurodegeneration, Royal College of Surgeons in Ireland, Dublin 2, Ireland [2] Institute for Stroke and Dementia Research (ISD), University of Munich Medical School-Campus Grosshadern, Max-Lebsche Platz 30, Munich D-81377, Germany.
References:
Hangen, E., Blomgren, K., Bénit, P., Kroemer, G., Modjtahedi, N., Life with or without AIF (2010) Trends Biochem Sci, 35, pp. 278-28
Sevrioukova, I.F., Apoptosis-inducing factor: Structure, function, and redox regulation (2011) Antioxid Redox Signal, 14, pp. 2545-2579
Polster, B.M., AIF, reactive oxygen species, and neurodegeneration: A "complex" problem (2013) Neurochem Int, 62, pp. 695-702
Vahsen, N., Candéc, Brière, J.J., Bénit, P., Joza, N., Larochette, N., AIF deficiency compromises oxidative phosphorylation (2004) EMBO J, 23, pp. 4679-4689
Cheung, E.C., Joza, N., Steenaart, N.A., McClellan, K.A., Neuspiel, M., McNamara, S., Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis (2006) EMBO J, 25, pp. 4061-4073
Cao, G., Clark, R.S., Pei, W., Yin, W., Zhang, F., Sun, F.Y., Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation (2003) J Cereb Blood Flow Metab, 23, pp. 1137-1150
Pallast, S., Arai, K., Pekcec, A., Yigitkanli, K., Yu, Z., Wang, X., Increased nuclear apoptosisinducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway (2010) J Cereb Blood Flow Metab, 30, pp. 1157-1167
Plesnila, N., Zhu, C., Culmsee, C., Gröger, M., Moskowitz, M.A., Blomgren, K., Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia (2004) J Cereb Blood Flow Metab, 24, pp. 458-466
Thal, S.E., Zhu, C., Thal, S.C., Blomgren, K., Plesnila, N., Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice (2011) Neurosci Lett, 499, pp. 1-3
Culmsee, C., Zhu, C., Landshamer, S., Becattini, B., Wagner, E., Pellecchia, M., Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia (2005) J Neuroscience, 25, pp. 10262-10272
Slemmer, J.E., Zhu, C., Landshamer, S., Trabold, R., Grohm, J., Ardeshiri, A., Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury (2008) Am J Pathol, 173, pp. 1795-1805
Piao, C.S., Loane, D.J., Stoica, B.A., Li, S., Hanscom, M., Cabatbat, R., Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury (2012) Neurobiol Dis, 46, pp. 745-758
Candé, C., Vahsen, N., Kouranti, I., Schmitt, E., Daugas, E., Spahr, C., AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis (2004) Oncogene, 23, pp. 1514-1521
Zhu, C., Wang, X., Deinum, J., Huang, Z., Gao, J., Modjtahedi, N., Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxiaischemia (2007) J Exp Med, 204, pp. 1741-1748
Handschumacher, R.E., Harding, M.W., Rice, J., Drugge, R.J., Speicher, D.W., Cyclophilin: A specific cytosolic binding protein for cyclosporin A (1984) Science, 226, pp. 544-547
Goldner, F.M., Patrick, J.W., Neuronal localization of the cyclophilin A protein in the adult rat brain (1996) J Comp Neurol, 372, pp. 283-293
Montague, J.W., Hughes Jr., F.M., Cidlowski, J.A., Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis (1997) J Biol Chem, 272, pp. 6677-6684
Zhang, X.C., Wang, W.D., Wang, J.S., Pan, J.C., PPIase independent chaperone-like function of recombinant human Cyclophilin A during arginine kinase refolding (2013) FEBS Lett, 587, pp. 666-672
Gurbuxani, S., Schmitt, E., Cande, C., Parcellier, A., Hammann, A., Daugas, E., Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor (2003) Oncogene, 22, pp. 6669-6678
Fukui, M., Song, J.H., Choi, J., Choi, H.J., Zhu, B.T., Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells (2009) Eur J Pharmacol, 617, pp. 1-11
Artus, C., Boujrad, H., Bouharrour, A., Brunelle, M.N., Hoos, S., Yuste, V.J., AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX (2010) EMBO J, 29, pp. 1585-1599
Guo, X., Surface plasmon resonance based biosensor technique: A review (2012) J Biophotonics, 5, pp. 483-501
Susin, S.A., Lorenzo, H.K., Zamzami, N., Marzo, I., Snow, B.E., Brothers, G.M., Molecular characterization of mitochondrial apoptosis-inducing factor (1999) Nature, 397, pp. 441-446
Ke, H., Similarities and differences between human cyclophilin A and other beta-barrel structures. Structural refinement at 1.63A resolution (1992) J Mol Biol, 228, pp. 539-550
Grohm, J., Plesnila, N., Culmsee, C., Bid mediates fission, membrane permeabilization and perinuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death (2010) Brain Behav Immun, 24, pp. 831-838
Grohm, J., Kim, S.W., Mamrak, U., Tobaben, S., Cassidy-Stone, A., Nunnari, J., Inhibition of Drp1 provides neuroprotection in vitro and in vivo (2012) Cell Death Differ, 19, pp. 1446-1458
Petit, P.X., Susin, S.A., Zamzami, N., Mignotte, B., Kroemer, G., Mitochondria and programmed cell death: Back to the future (1996) FEBS Lett, 396, pp. 7-13
Tobaben, S., Grohm, J., Seiler, A., Conrad, M., Plesnila, N., Culmsee, C., Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons (2011) Cell Death Differ, 18, pp. 282-292
Smiley, S.T., Reers, M., Mottola-Hartshorn, C., Lin, M., Chen, A., Smith, T.W., Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1 (1991) Proc Natl Acad Sci USA, 88, pp. 3671-3675
Xu, J., Hao, Z., Gou, X., Tian, W., Jin, Y., Cui, S., Imaging of reactive oxygen species burst from mitochondria using laser scanning confocal microscopy (2013) Microsc Res Tech, 76, pp. 612-617
Pinton, P., Giorgi, C., Siviero, R., Zecchini, E., Rizzuto, R., Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis (2008) Oncogene, 27, pp. 6407-6418
Utkina-Sosunova, I.V., Niatsetskaya, Z.V., Sosunov, S.A., Ratner, V.I., Matsiukevich, D., Ten, V.S., Nelfinavir inhibits intra-mitochondrial calcium influx and protects brain against hypoxicischemic injury in neonatal mice (2013) PLoS One, 8, pp. e62448
Cao, G., Xing, J., Xiao, X., Liou, A.F.K., Yin, X.M., Clark, R.S.B., Critical role of calpain i in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury (2007) J Neurosci, 27, pp. 9278-9293
Wang, P., Heitman, J., The cyclophilins (2005) Genome Biol, 6, p. 226
Yu, S.W., Wang, Y., Frydenlund, D.S., Ottersen, O.P., Dawson, V.L., Dawson, T.M., Outer mitochondrial membrane localization of apoptosis-inducing factor: Mechanistic implications for release (2009) ASN Neuro, 1, pp. e00021
Tremper-Wells, B., Vallano, M.L., Nuclear calpain regulates Ca2+-dependent signaling via proteolysis of nuclear Ca2+/calmodulin-dependent protein kinase type IV in cultured neurons (2005) J Biol Chem, 280, pp. 2165-2175
Fields, G.B., Noble, R.L., Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids (1990) Int J Pept Protein Res, 35, pp. 161-214
Johnsson, B., Lofas, S., Lindquist, G., Immobilization of proteins to a carboxymethyldextran modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors (1991) Anal Biochem, 198, pp. 268-277
Dolga, A.M., Letsche, T., Gold, M., Doti, N., Bacher, M., Chiamvimonvat, N., Activation of KCNN3/SK3/K(Ca) 2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia (2012) Glia, 60, pp. 2050-2064
Myszka, D.G., Analysis of small-molecule interactions using Biacore S51 technology (2004) Anal Biochem, 329, pp. 316-323
Diemert, S., Dolga, A.M., Tobaben, S., Grohm, J., Pfeifer, S., Oexler, E., Impedance measurement for real time detection of neuronal cell death (2012) J Neurosci Methods, 203, pp. 69-77
Öxler, E.M., Dolga, A., Culmsee, C., AIF depletion provides neuroprotection through a preconditioning effect (2012) Apoptosis, 17, pp. 1027-1038
Sevrioukova, I. F., Apoptosis-inducing factor: Structure, function, and redox regulation (2011) Antioxid Redox Signal, 14, pp. 2545-2579
Polster, B. M., AIF, reactive oxygen species, and neurodegeneration: A "complex" problem (2013) Neurochem Int, 62, pp. 695-702
Vahsen, N., Cand c, Bri re, J. J., B nit, P., Joza, N., Larochette, N., AIF deficiency compromises oxidative phosphorylation (2004) EMBO J, 23, pp. 4679-4689
Cheung, E. C., Joza, N., Steenaart, N. A., McClellan, K. A., Neuspiel, M., McNamara, S., Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis (2006) EMBO J, 25, pp. 4061-4073
Cao, G., Clark, R. S., Pei, W., Yin, W., Zhang, F., Sun, F. Y., Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation (2003) J Cereb Blood Flow Metab, 23, pp. 1137-1150
Thal, S. E., Zhu, C., Thal, S. C., Blomgren, K., Plesnila, N., Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice (2011) Neurosci Lett, 499, pp. 1-3
Slemmer, J. E., Zhu, C., Landshamer, S., Trabold, R., Grohm, J., Ardeshiri, A., Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury (2008) Am J Pathol, 173, pp. 1795-1805
Piao, C. S., Loane, D. J., Stoica, B. A., Li, S., Hanscom, M., Cabatbat, R., Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury (2012) Neurobiol Dis, 46, pp. 745-758
Cand, C., Vahsen, N., Kouranti, I., Schmitt, E., Daugas, E., Spahr, C., AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis (2004) Oncogene, 23, pp. 1514-1521
Handschumacher, R. E., Harding, M. W., Rice, J., Drugge, R. J., Speicher, D. W., Cyclophilin: A specific cytosolic binding protein for cyclosporin A (1984) Science, 226, pp. 544-547
Goldner, F. M., Patrick, J. W., Neuronal localization of the cyclophilin A protein in the adult rat brain (1996) J Comp Neurol, 372, pp. 283-293
Montague, J. W., Hughes Jr., F. M., Cidlowski, J. A., Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis (1997) J Biol Chem, 272, pp. 6677-6684
Zhang, X. C., Wang, W. D., Wang, J. S., Pan, J. C., PPIase independent chaperone-like function of recombinant human Cyclophilin A during arginine kinase refolding (2013) FEBS Lett, 587, pp. 666-672
Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Molecular characterization of mitochondrial apoptosis-inducing factor (1999) Nature, 397, pp. 441-446
Grohm, J., Kim, S. W., Mamrak, U., Tobaben, S., Cassidy-Stone, A., Nunnari, J., Inhibition of Drp1 provides neuroprotection in vitro and in vivo (2012) Cell Death Differ, 19, pp. 1446-1458
Petit, P. X., Susin, S. A., Zamzami, N., Mignotte, B., Kroemer, G., Mitochondria and programmed cell death: Back to the future (1996) FEBS Lett, 396, pp. 7-13
Smiley, S. T., Reers, M., Mottola-Hartshorn, C., Lin, M., Chen, A., Smith, T. W., Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1 (1991) Proc Natl Acad Sci USA, 88, pp. 3671-3675
Yu, S. W., Wang, Y., Frydenlund, D. S., Ottersen, O. P., Dawson, V. L., Dawson, T. M., Outer mitochondrial membrane localization of apoptosis-inducing factor: Mechanistic implications for release (2009) ASN Neuro, 1, pp. e00021
Fields, G. B., Noble, R. L., Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids (1990) Int J Pept Protein Res, 35, pp. 161-214
Dolga, A. M., Letsche, T., Gold, M., Doti, N., Bacher, M., Chiamvimonvat, N., Activation of KCNN3/SK3/K (Ca) 2. 3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia (2012) Glia, 60, pp. 2050-2064
Myszka, D. G., Analysis of small-molecule interactions using Biacore S51 technology (2004) Anal Biochem, 329, pp. 316-323
xler, E. M., Dolga, A., Culmsee, C., AIF depletion provides neuroprotection through a preconditioning effect (2012) Apoptosis, 17, pp. 1027-1038
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2014 Jan 16; 5(1): e993-e993.
Export to BibTeX Export to EndNote
Paper type: Abstract, Conference, Research Support, Non-U. S. Gov'T,
Impact factor: 5.014, 5-year impact factor: 5.291
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84891783666&partnerID=40&md5=a53c824ae1c04cb0100246b242c5ca34
Keywords: Aif Cypa Complex, Mitochondria, Neuronal Death, Oxidative Stress, Peptide Inhibitor, Apoptosis Inducing Factor, Calcium Ion, Cyclophilin A, Glutamic Acid, Small Interfering Rna, Article, Cell Survival, Complex Formation, Controlled Study, In Vitro Study, Intracellular Signaling, Mitochondrial Membrane Potential, Nerve Cell Necrosis, Neuroprotection, Priority Journal, Protein Binding, Protein Expression, Protein Protein Interaction, Protein Secretion, Protein Transport, Amino Acid Motifs, Down-Regulation, Humans, Apoptosis Inducing Factor Chemistry Genetics Metabolism, Cyclophilin A Genetics Metabolism, Mitochondria Enzymology Metabolism, Neurons Cytology Enzymology Metabolism,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging (IBB), CNR, CIRPEB, Via Mezzocannone, 16, Naples 80134, Italy
Institute of Pharmacology and Clinical Pharmacy, Philipps University of Marburg, Karl-von-Frisch-Straße 1, Marburg 35032, Germany
Department of Neurodegeneration, Royal College of Surgeons in Ireland, Dublin 2, Ireland
Institute for Stroke and Dementia Research (ISD), University of Munich Medical School-Campus Großhadern, Max-Lebsche Platz 30, Munich 81377, Germany
1] Institute of Biostructures and Bioimaging (IBB)-CNR, CIRPEB, Via Mezzocannone, 16, Naples 80134, Italy [2] Institute of Pharmacology and Clinical Pharmacy, Philipps University of Marburg, Marburg 35032, Germany [3] Department of Neurodegeneration, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
1] Department of Neurodegeneration, Royal College of Surgeons in Ireland, Dublin 2, Ireland [2] Institute for Stroke and Dementia Research (ISD), University of Munich Medical School-Campus Grosshadern, Max-Lebsche Platz 30, Munich D-81377, Germany.
References:
Hangen, E., Blomgren, K., Bénit, P., Kroemer, G., Modjtahedi, N., Life with or without AIF (2010) Trends Biochem Sci, 35, pp. 278-28
Sevrioukova, I.F., Apoptosis-inducing factor: Structure, function, and redox regulation (2011) Antioxid Redox Signal, 14, pp. 2545-2579
Polster, B.M., AIF, reactive oxygen species, and neurodegeneration: A "complex" problem (2013) Neurochem Int, 62, pp. 695-702
Vahsen, N., Candéc, Brière, J.J., Bénit, P., Joza, N., Larochette, N., AIF deficiency compromises oxidative phosphorylation (2004) EMBO J, 23, pp. 4679-4689
Cheung, E.C., Joza, N., Steenaart, N.A., McClellan, K.A., Neuspiel, M., McNamara, S., Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis (2006) EMBO J, 25, pp. 4061-4073
Cao, G., Clark, R.S., Pei, W., Yin, W., Zhang, F., Sun, F.Y., Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation (2003) J Cereb Blood Flow Metab, 23, pp. 1137-1150
Pallast, S., Arai, K., Pekcec, A., Yigitkanli, K., Yu, Z., Wang, X., Increased nuclear apoptosisinducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway (2010) J Cereb Blood Flow Metab, 30, pp. 1157-1167
Plesnila, N., Zhu, C., Culmsee, C., Gröger, M., Moskowitz, M.A., Blomgren, K., Nuclear translocation of apoptosis-inducing factor after focal cerebral ischemia (2004) J Cereb Blood Flow Metab, 24, pp. 458-466
Thal, S.E., Zhu, C., Thal, S.C., Blomgren, K., Plesnila, N., Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice (2011) Neurosci Lett, 499, pp. 1-3
Culmsee, C., Zhu, C., Landshamer, S., Becattini, B., Wagner, E., Pellecchia, M., Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia (2005) J Neuroscience, 25, pp. 10262-10272
Slemmer, J.E., Zhu, C., Landshamer, S., Trabold, R., Grohm, J., Ardeshiri, A., Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury (2008) Am J Pathol, 173, pp. 1795-1805
Piao, C.S., Loane, D.J., Stoica, B.A., Li, S., Hanscom, M., Cabatbat, R., Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury (2012) Neurobiol Dis, 46, pp. 745-758
Candé, C., Vahsen, N., Kouranti, I., Schmitt, E., Daugas, E., Spahr, C., AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis (2004) Oncogene, 23, pp. 1514-1521
Zhu, C., Wang, X., Deinum, J., Huang, Z., Gao, J., Modjtahedi, N., Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxiaischemia (2007) J Exp Med, 204, pp. 1741-1748
Handschumacher, R.E., Harding, M.W., Rice, J., Drugge, R.J., Speicher, D.W., Cyclophilin: A specific cytosolic binding protein for cyclosporin A (1984) Science, 226, pp. 544-547
Goldner, F.M., Patrick, J.W., Neuronal localization of the cyclophilin A protein in the adult rat brain (1996) J Comp Neurol, 372, pp. 283-293
Montague, J.W., Hughes Jr., F.M., Cidlowski, J.A., Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis (1997) J Biol Chem, 272, pp. 6677-6684
Zhang, X.C., Wang, W.D., Wang, J.S., Pan, J.C., PPIase independent chaperone-like function of recombinant human Cyclophilin A during arginine kinase refolding (2013) FEBS Lett, 587, pp. 666-672
Gurbuxani, S., Schmitt, E., Cande, C., Parcellier, A., Hammann, A., Daugas, E., Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor (2003) Oncogene, 22, pp. 6669-6678
Fukui, M., Song, J.H., Choi, J., Choi, H.J., Zhu, B.T., Mechanism of glutamate-induced neurotoxicity in HT22 mouse hippocampal cells (2009) Eur J Pharmacol, 617, pp. 1-11
Artus, C., Boujrad, H., Bouharrour, A., Brunelle, M.N., Hoos, S., Yuste, V.J., AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX (2010) EMBO J, 29, pp. 1585-1599
Guo, X., Surface plasmon resonance based biosensor technique: A review (2012) J Biophotonics, 5, pp. 483-501
Susin, S.A., Lorenzo, H.K., Zamzami, N., Marzo, I., Snow, B.E., Brothers, G.M., Molecular characterization of mitochondrial apoptosis-inducing factor (1999) Nature, 397, pp. 441-446
Ke, H., Similarities and differences between human cyclophilin A and other beta-barrel structures. Structural refinement at 1.63A resolution (1992) J Mol Biol, 228, pp. 539-550
Grohm, J., Plesnila, N., Culmsee, C., Bid mediates fission, membrane permeabilization and perinuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death (2010) Brain Behav Immun, 24, pp. 831-838
Grohm, J., Kim, S.W., Mamrak, U., Tobaben, S., Cassidy-Stone, A., Nunnari, J., Inhibition of Drp1 provides neuroprotection in vitro and in vivo (2012) Cell Death Differ, 19, pp. 1446-1458
Petit, P.X., Susin, S.A., Zamzami, N., Mignotte, B., Kroemer, G., Mitochondria and programmed cell death: Back to the future (1996) FEBS Lett, 396, pp. 7-13
Tobaben, S., Grohm, J., Seiler, A., Conrad, M., Plesnila, N., Culmsee, C., Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons (2011) Cell Death Differ, 18, pp. 282-292
Smiley, S.T., Reers, M., Mottola-Hartshorn, C., Lin, M., Chen, A., Smith, T.W., Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1 (1991) Proc Natl Acad Sci USA, 88, pp. 3671-3675
Xu, J., Hao, Z., Gou, X., Tian, W., Jin, Y., Cui, S., Imaging of reactive oxygen species burst from mitochondria using laser scanning confocal microscopy (2013) Microsc Res Tech, 76, pp. 612-617
Pinton, P., Giorgi, C., Siviero, R., Zecchini, E., Rizzuto, R., Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis (2008) Oncogene, 27, pp. 6407-6418
Utkina-Sosunova, I.V., Niatsetskaya, Z.V., Sosunov, S.A., Ratner, V.I., Matsiukevich, D., Ten, V.S., Nelfinavir inhibits intra-mitochondrial calcium influx and protects brain against hypoxicischemic injury in neonatal mice (2013) PLoS One, 8, pp. e62448
Cao, G., Xing, J., Xiao, X., Liou, A.F.K., Yin, X.M., Clark, R.S.B., Critical role of calpain i in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury (2007) J Neurosci, 27, pp. 9278-9293
Wang, P., Heitman, J., The cyclophilins (2005) Genome Biol, 6, p. 226
Yu, S.W., Wang, Y., Frydenlund, D.S., Ottersen, O.P., Dawson, V.L., Dawson, T.M., Outer mitochondrial membrane localization of apoptosis-inducing factor: Mechanistic implications for release (2009) ASN Neuro, 1, pp. e00021
Tremper-Wells, B., Vallano, M.L., Nuclear calpain regulates Ca2+-dependent signaling via proteolysis of nuclear Ca2+/calmodulin-dependent protein kinase type IV in cultured neurons (2005) J Biol Chem, 280, pp. 2165-2175
Fields, G.B., Noble, R.L., Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids (1990) Int J Pept Protein Res, 35, pp. 161-214
Johnsson, B., Lofas, S., Lindquist, G., Immobilization of proteins to a carboxymethyldextran modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors (1991) Anal Biochem, 198, pp. 268-277
Dolga, A.M., Letsche, T., Gold, M., Doti, N., Bacher, M., Chiamvimonvat, N., Activation of KCNN3/SK3/K(Ca) 2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia (2012) Glia, 60, pp. 2050-2064
Myszka, D.G., Analysis of small-molecule interactions using Biacore S51 technology (2004) Anal Biochem, 329, pp. 316-323
Diemert, S., Dolga, A.M., Tobaben, S., Grohm, J., Pfeifer, S., Oexler, E., Impedance measurement for real time detection of neuronal cell death (2012) J Neurosci Methods, 203, pp. 69-77
Öxler, E.M., Dolga, A., Culmsee, C., AIF depletion provides neuroprotection through a preconditioning effect (2012) Apoptosis, 17, pp. 1027-1038
Sevrioukova, I. F., Apoptosis-inducing factor: Structure, function, and redox regulation (2011) Antioxid Redox Signal, 14, pp. 2545-2579
Polster, B. M., AIF, reactive oxygen species, and neurodegeneration: A "complex" problem (2013) Neurochem Int, 62, pp. 695-702
Vahsen, N., Cand c, Bri re, J. J., B nit, P., Joza, N., Larochette, N., AIF deficiency compromises oxidative phosphorylation (2004) EMBO J, 23, pp. 4679-4689
Cheung, E. C., Joza, N., Steenaart, N. A., McClellan, K. A., Neuspiel, M., McNamara, S., Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis (2006) EMBO J, 25, pp. 4061-4073
Cao, G., Clark, R. S., Pei, W., Yin, W., Zhang, F., Sun, F. Y., Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation (2003) J Cereb Blood Flow Metab, 23, pp. 1137-1150
Thal, S. E., Zhu, C., Thal, S. C., Blomgren, K., Plesnila, N., Role of apoptosis inducing factor (AIF) for hippocampal neuronal cell death following global cerebral ischemia in mice (2011) Neurosci Lett, 499, pp. 1-3
Slemmer, J. E., Zhu, C., Landshamer, S., Trabold, R., Grohm, J., Ardeshiri, A., Causal role of apoptosis-inducing factor for neuronal cell death following traumatic brain injury (2008) Am J Pathol, 173, pp. 1795-1805
Piao, C. S., Loane, D. J., Stoica, B. A., Li, S., Hanscom, M., Cabatbat, R., Combined inhibition of cell death induced by apoptosis inducing factor and caspases provides additive neuroprotection in experimental traumatic brain injury (2012) Neurobiol Dis, 46, pp. 745-758
Cand, C., Vahsen, N., Kouranti, I., Schmitt, E., Daugas, E., Spahr, C., AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis (2004) Oncogene, 23, pp. 1514-1521
Handschumacher, R. E., Harding, M. W., Rice, J., Drugge, R. J., Speicher, D. W., Cyclophilin: A specific cytosolic binding protein for cyclosporin A (1984) Science, 226, pp. 544-547
Goldner, F. M., Patrick, J. W., Neuronal localization of the cyclophilin A protein in the adult rat brain (1996) J Comp Neurol, 372, pp. 283-293
Montague, J. W., Hughes Jr., F. M., Cidlowski, J. A., Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis (1997) J Biol Chem, 272, pp. 6677-6684
Zhang, X. C., Wang, W. D., Wang, J. S., Pan, J. C., PPIase independent chaperone-like function of recombinant human Cyclophilin A during arginine kinase refolding (2013) FEBS Lett, 587, pp. 666-672
Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Molecular characterization of mitochondrial apoptosis-inducing factor (1999) Nature, 397, pp. 441-446
Grohm, J., Kim, S. W., Mamrak, U., Tobaben, S., Cassidy-Stone, A., Nunnari, J., Inhibition of Drp1 provides neuroprotection in vitro and in vivo (2012) Cell Death Differ, 19, pp. 1446-1458
Petit, P. X., Susin, S. A., Zamzami, N., Mignotte, B., Kroemer, G., Mitochondria and programmed cell death: Back to the future (1996) FEBS Lett, 396, pp. 7-13
Smiley, S. T., Reers, M., Mottola-Hartshorn, C., Lin, M., Chen, A., Smith, T. W., Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1 (1991) Proc Natl Acad Sci USA, 88, pp. 3671-3675
Yu, S. W., Wang, Y., Frydenlund, D. S., Ottersen, O. P., Dawson, V. L., Dawson, T. M., Outer mitochondrial membrane localization of apoptosis-inducing factor: Mechanistic implications for release (2009) ASN Neuro, 1, pp. e00021
Fields, G. B., Noble, R. L., Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids (1990) Int J Pept Protein Res, 35, pp. 161-214
Dolga, A. M., Letsche, T., Gold, M., Doti, N., Bacher, M., Chiamvimonvat, N., Activation of KCNN3/SK3/K (Ca) 2. 3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia (2012) Glia, 60, pp. 2050-2064
Myszka, D. G., Analysis of small-molecule interactions using Biacore S51 technology (2004) Anal Biochem, 329, pp. 316-323
xler, E. M., Dolga, A., Culmsee, C., AIF depletion provides neuroprotection through a preconditioning effect (2012) Apoptosis, 17, pp. 1027-1038
Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress
Delayed neuronal cell death largely contributes to the progressive infarct development and associated functional impairments after cerebral ischemia or brain trauma. Previous studies exposed a key role for the interaction of the mitochondrial protein apoptosis-inducing factor (AIF) and cytosolic cyclophilin A (CypA) in pathways of programmed cell death in neurons in vitro and in vivo. These studies suggested that pro-apoptotic activities of AIF, such as its translocation to the nucleus and subsequent DNA degradation, depend on the physical interaction of AIF with CypA. Hence, this protein complex may represent a new pharmacological target for inhibiting the lethal action of AIF on the brain tissue. In this study, we show that the AIF amino-acid residues 370-394 mediate the protein complex formation of AIF with CypA. The synthetic AIF(370-394) peptide inhibited AIF/CypA complex formation in vitro by binding CypA with a KD of 12 μM. Further, the peptide exerted pronounced neuroprotective effects in a model of glutamate-induced oxidative stress in cultured HT-22 cells. In this model system of AIF-dependent cell death, the AIF(370-394) peptide preserved mitochondrial integrity, as detected by measurements of the mitochondrial membrane potential and quantification of mitochondrial fragmentation. Further, the AIF(370-394) peptide inhibited perinuclear accumulation of fragmented mitochondria, mitochondrial release of AIF to the nucleus and glutamate-induced cell death to a similar extent as CypA-siRNA. These data indicate that the targeting of the AIF-CypA axis is an effective strategy of neuroprotection. © 2014 Macmillan Publishers Limited.
Delayed neuronal cell death largely contributes to the progressive infarct development and associated functional impairments after cerebral ischemia or brain trauma. Previous studies exposed a key role for the interaction of the mitochondrial protein apoptosis-inducing factor (AIF) and cytosolic cyclophilin A (CypA) in pathways of programmed cell death in neurons in vitro and in vivo. These studies suggested that pro-apoptotic activities of AIF, such as its translocation to the nucleus and subsequent DNA degradation, depend on the physical interaction of AIF with CypA. Hence, this protein complex may represent a new pharmacological target for inhibiting the lethal action of AIF on the brain tissue. In this study, we show that the AIF amino-acid residues 370-394 mediate the protein complex formation of AIF with CypA. The synthetic AIF(370-394) peptide inhibited AIF/CypA complex formation in vitro by binding CypA with a KD of 12 μM. Further, the peptide exerted pronounced neuroprotective effects in a model of glutamate-induced oxidative stress in cultured HT-22 cells. In this model system of AIF-dependent cell death, the AIF(370-394) peptide preserved mitochondrial integrity, as detected by measurements of the mitochondrial membrane potential and quantification of mitochondrial fragmentation. Further, the AIF(370-394) peptide inhibited perinuclear accumulation of fragmented mitochondria, mitochondrial release of AIF to the nucleus and glutamate-induced cell death to a similar extent as CypA-siRNA. These data indicate that the targeting of the AIF-CypA axis is an effective strategy of neuroprotection. © 2014 Macmillan Publishers Limited.
Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress
Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress
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Sorriento D, Fusco A, Ciccarelli M, Rungi A, Anastasio A, Carillo A, Dorn II GW, Trimarco B, Iaccarino G
* Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages (385 views)
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Impact Factor: 3.341
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Forestier A, Douki T, Sauvaigo S, De Rosa V, Demeilliers C, Rachidi W
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Impact Factor: 2.464
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
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Impact Factor: 3.914
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3606 views)
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Impact Factor: 3.733
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Sandomenico A, Russo A, Palmieri G, Bergamo P, Gogliettino M, Falcigno L, Ruvo M
* Small peptide inhibitors of acetyl-peptide hydrolase having an uncommon mechanism of inhibition and a stable bent conformation (520 views)
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Impact Factor: 5.614
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Truppo E, Supuran CT, Sandomenico A, Vullo D, Innocenti A, Di Fiore A, Alterio V, De Simone G, Monti SM
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Impact Factor: 2.338
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (550 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Fusco A, Santulli G, Sorriento D, Cipolletta E, Garbi C, Dorn GW, Trimarco B, Feliciello A, Iaccarino G
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Cell Signal (ISSN: 0898-6568), 2012; 24(2): 468-475.
Impact Factor: 4.304
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Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (880 views)
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Impact Factor: 9.97
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Corona C, Frazzini V, Silvestri E, Lattanzio R, La Sorda R, Piantelli M, Canzoniero LM, Ciavardelli D, Rizzarelli E, Sensi SL
* Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice (553 views)
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Impact Factor: 4.092
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Rachidi W, De Rosa V
Selenium protects against the cytotoxic and genotoxic effects of oxidative stress both as an anti-oxidant and by stimulating DNA damage repair (306 views)
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Impact Factor: 0.672
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
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Impact Factor: 3.354
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Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (429 views)
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Impact Factor: 2.608
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Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro L, Del Gatto A, Saviano M, Garbi C, Carangi R, Di Lorenzo E, Donato G, Indolfi C, Avvedimento VE, Chiariello M
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Impact Factor: 6.051
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (554 views)
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Impact Factor: 5.707
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Castellano I, Merlino A, Rossi M, La Cara F
* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (613 views)
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Impact Factor: 3.787
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De Rosa V, Diamond A, Favier A, Douki T, Rachidi W
* Effect of selenium on lethal and genotoxic properties of oxidative stress (206 views)
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Impact Factor: 0.887
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
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Impact Factor: 7.581
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Lettieri A, Salvatore M
* Molecular imaging of drug resistance in cancer (438 views)
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Impact Factor: 0.268
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De Rosa V, Alan D, Alain F, Thierry D, Walid R
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Impact Factor: 0.792
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
* Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases (1144 views)
Frontiers In Bioscience (ISSN: 1093-4715, 1093-9946), 2009 Jan 1; 14: 376-397.
Impact Factor: 3.736
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (1232 views)
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Impact Factor: 2.26
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
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Impact Factor: 2.26
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Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (550 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
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Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
* Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type (537 views)
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Impact Factor: 6.488
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Supuran CT, Di Fiore A, De Simone G
* Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity (562 views)
Expert Opin Emerg Drugsexpert Opinion On Emerging Drugs (ISSN: 1472-8214), 2008 Jun; 13(2): 383-392.
Impact Factor: 3.08
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Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (366 views)
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Impact Factor: 3.139
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Caraci F, Battaglia G, Busceti C, Biagioni F, Mastroiacovo F, Bosco P, Drago F, Nicoletti F, Sortino MA, Copani A
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Neurobiology Of Disease (ISSN: 0969-9961), 2008 May; 30(2): 234-242.
Impact Factor: 4.852
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Atlante A, Amadoro G, Bobba A, de Bari L, Corsetti V, Pappalardo G, Marra E, Calissano P, Passarella S
* A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator (507 views)
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Impact Factor: 4.447
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (407 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
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Vitale RM, Pedone C, Amodeo P, Antel J, Wurl M, Scozzafava A, Supuran CT, De Simone G
* Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA (335 views)
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Impact Factor: 2.662
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Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C
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Am J Physiol Lung Cell Mol Physiol (ISSN: 1040-0605), 2007 May; 292(5): L1095-L1095.
Impact Factor: 4.214
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Galdiero S, Galdiero M, Pedone C
* Beta-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly And Interaction With Lipids (438 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2007 Feb; 8(1): 63-82.
Impact Factor: 3.259
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Ronga L, Palladino P, Costantini S, Facchiano A, Ruvo M, Benedetti E, Ragone R, Rossi F
* Conformational diseases and structure-toxicity relationships: Lessons from prion-derived peptides (553 views)
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Impact Factor: 3.259
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Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (522 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
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Pedone E, Limauro D, D'Alterio R, Rossi M, Bartolucci S
* Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus (328 views)
Febs Journal (ISSN: 1742-464x), 2006 Dec; 273(23): 5407-5420.
Impact Factor: 3.033
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Palumbo R, Capasso D, Brescia F, Mita P, Sarti M, Bersani F, Scarfi MR
* Effects on apoptosis and reactive oxygen species formation by Jurkat cells exposed to 50 Hz electromagnetic fields (596 views)
Bioelectromagnetics (ISSN: 0197-8462), 2006 Feb; 27(2): 159-162.
Impact Factor: 1.514
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Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (362 views)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
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Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, Scozzafava A, Wurl M, Supuran CT
* Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies (420 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 May 2; 15(9): 2315-2320.
Impact Factor: 2.478
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Pedone E, Bartolucci S, Fiorentino G
* Sensing and adapting to environmental stress: The Archaeal tactic (327 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2004 Sep 1; 9: 2909-2926.
Impact Factor: 3.226
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De Capua A, Del Gatto A, Zaccaro L, Saviano G, Carlucci A, Livigni A, Gedressi C, Tancredi T, Pedone C, Saviano M
* A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: A conformational study (475 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 459-466.
Impact Factor: 2.863
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Saviano M, Zaccaro L, Benedetti E, Pedone C, Del Gatto A, Feliciello A, Affaiatati A, Avvedimento EV
* Development of peptides able to modulate the interaction of AKAP121 with mitochondria (418 views)
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (527 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Tabbì G, Cassino C, Cavigiolio G, Colangelo D, Ghiglia A, Viano I, Osella D
* Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process (642 views)
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Impact Factor: 4.566
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Cardone L, de Cristofaro T, Affaitati A, Garbi C, Ginsberg MD, Saviano M, Varrone S, Rubin CS, Gottesman ME, Avvedimento EV, Feliciello A
* A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs (654 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2002 Jul 12; 320(3): 663-675.
Impact Factor: 5.359
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Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (883 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
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Ogawa R, Pacelli R, Espey MG, Miranda KM, Friedman N, Kim SM, Cox G, Mitchell JB, Wink DA, Russo A
* Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and no donors: Insights into listeriocidal activity of oxidative and nitrosative stress (688 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2001 Feb 1; 30(3): 268-276.
Impact Factor: 5.082
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Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (564 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
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Russo M, Palumbo R, Tedesco I, Mazzarella G, Russo P, Iacomino G, Russo GL
Quercetin and anti-CD95(Fas/Apo1) enhance apoptosis in HPB-ALL cell line (402 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 1999 Dec 3; 462(3): 322-328.
Impact Factor: 3.72
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Wink DA, Vodovotz Y, Grisham MB, DeGraff W, Cook JC, Pacelli R, Krishna M, Mitchell JB
Antioxidant effects of nitric oxide (351 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 1998; 301: 413-424.
Impact Factor: 2.823
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Wink DA, Cook JA, Kim SY, Vodovotz Y, Pacelli R, Krishna MC, Russo A, Mitchell JB, Jourd'heuil D, Miles AM, Grisham MB
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates (336 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 1997 Apr 25; 272(17): 11147-11151.
Impact Factor: 6.963
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Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB
Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms (691 views)
Current Topics In Cellular Regulation (ISSN: 0070-2137), 1996; 34: 159-187.
Impact Factor: 4.375
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Wink DA, Cook JA, Pacelli R, Liebmann J, Krishna MC, Mitchell JB
Nitric oxide (NO) protects against cellular damage by reactive oxygen species (526 views)
Toxicology Letters (ISSN: 0378-4274), 1995 Dec; 82-3: 221-226.
Impact Factor: 1.128
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (587 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
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Condorelli G, Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
INHIBITION OF PHOTOHEMOLYSIS BY COPPER(II) COMPLEXES WITH SOD-LIKE ACTIVITY (489 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Jun; 54(4): 257-265.
Impact Factor: 1.342
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* Targeting Mitochondrial Therapy in the Regulation of HPV Infection and HPV-Related Cancers (6 views)
Pathogens, 2023 Mar; 12(3): 402-417.
Impact Factor: 4.531
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Fatima N, Baqri SSR, Alsulimani A, Fagoonee S, Slama P, Kesari KK, Roychoudhury S, Haque S
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La Manna S, Lopez-sanz L, Bernal S, Fortuna S, Mercurio FA, Leone M, Gomez-guerrero C, Marasco D
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De Rosa V, Iommelli F, Terlizzi C, Leggiero E, Camerlingo R, Altobelli GG, Fonti R, Pastore L, Del Vecchio S
* Non-Canonical Role of PDK1 as a Negative Regulator of Apoptosis through Macromolecular Complexes Assembly at the ER-Mitochondria Interface in Oncogene-Driven NSCLC (16 views)
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Chelko SP, Keceli G, Carpi A, Doti N, Agrimi J, Asimaki A, Beti CB, Miyamoto M, Amat-codina N, Bedja D, Wei AC, Murray B, Tichnell C, Kwon C, Calkins H, James CA, O , #rourke B, Halushka MK, Melloni E, Saffitz JE, Judge DP, Ruvo M, Kitsis RN, Andersen P, Di Lisa F, Paolocci N
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Impact Factor: 17.956
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Monti A, Sturlese M, Caporale A, Roger JA, Mascanzoni F, Ruvo M, Doti N
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Impact Factor: 3.422
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Pedone E, Fiorentino G, Bartolucci S, Limauro D
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Impact Factor: 4.52
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Tarallo V, Iaccarino E, Cicatiello V, Sanna R, Ruvo M, De Falco S
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Impact Factor: 2.598
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Negri R, Trinchese G, Carbone F, Caprio MG, Stanzione G, Di Scala C, Micillo T, Perna F, Tarotto L, Gelzo M, Cavaliere G, Spagnuolo MI, Corso G, Mattace Raso G, Matarese G, Mollica MP, Greco L, Iorio R
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Barone R, Alaimo S, Messina M, Pulvirenti A, Bastin J, Group MIMIC-A, F , Frye RE, Rizzo (mimic-ag A, Fiumara R, Meli C, Gulisano M, Maugeri F, Prato A, Russo G, Tabbì G
* A Subset of Patients With Autism Spectrum Disorders Show a Distinctive Metabolic Profile by Dried Blood Spot Analyses (182 views) (PDF 101 views)
Front Psychiatry (ISSN: 1664-0640linking), 2018 Dec 7; 9: 636-636.
Impact Factor: 2.857
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De Michele G, Sorrentino P, Nesti C, Rubegni A, Ruggiero L, Peluso S, Antenora A, Quarantelli M, Filla A, De Michele G, Santorelli FM
* Reversible Valproate-Induced Subacute Encephalopathy Associated With a MT-ATP8 Variant in the Mitochondrial Genome (271 views)
Front Neurol (ISSN: 1664-2295linking, 1664-2295print), 2018 Aug 30; 9(AUG): 728-728.
Impact Factor: 3.508
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Falanga A, Mercurio FA, Siciliano A, Lombardi L, Galdiero S, Guida M, Libralato G, Leone M, Galdiero E
* Metabolomic and oxidative effects of quantum dots-indolicidin on three generations of Daphnia magna (91 views)
Aquat Toxicol (ISSN: 0166-445xlinking), 2018 May; 198: 158-164.
Impact Factor: 0
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Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F
* Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system (396 views)
Neuropharm (ISSN: 0028-3908linking, 1873-7064electronic), 2018 Jan; 128: 301-313.
Impact Factor: 3.383
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Mercurio FA, Di Natale C, Pirone L, Iannitti R, Marasco D, Pedone EM, Palumbo R, Leone M
* The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors (269 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Dec 12; 7(1): 17474-17474.
Impact Factor: 4.122
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Monti DM, De Simone G, Langella E, Supuran CT, Di Fiore A, Monti SM
* Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage (354 views)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2017 Dec; 32(1): 5-12.
Impact Factor: 3.638
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Dell'Acqua S, Bacchella C, Monzani E, Nicolis S, Di Natale G, Rizzarelli E, Casella L
* Prion Peptides Are Extremely Sensitive to Copper Induced Oxidative Stress (585 views)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2017 Sep 18; 56(18): 11317-11325.
Impact Factor: 4.7
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Ingoglia G, Sag CM, Rex N, De Franceschi L, Vinchi F, Cimino J, Petrillo S, Wagner S, Kreitmeier K, Silengo L, Altruda F, Maier LS, Hirsch E, Ghigo A, Tolosano E
* Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress (167 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking), 2017 Jul; 108: 452-464.
Impact Factor: 6.02
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Skiba J, Bernas T, Trzybinski D, Wozniak K, Ferraro G, Marasco D, Merlino A, Shafikov MZ, Czerwieniec R, Kowalski K
* Mitochondria Targeting with Luminescent Rhenium(I) Complexes (316 views)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2017 May 15; 22(5): N/D-N/D.
Impact Factor: 3.098
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Ingoglia G, Sag CM, Rex N, De Franceschi L, Vinchi F, Cimino J, Petrillo S, Wagner S, Kreitmeier K, Silengo L, Altruda F, Maier LS, Hirsch E, Ghigo A, Tolosano E
* Data demonstrating the anti-oxidant role of hemopexin in the heart (163 views)
Data Brief (ISSN: 2352-3409print, 2352-3409linking), 2017 May 13; 13: 69-76.
Impact Factor: 0
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Simoni E, Caporaso R, Bergamini C, Fiori J, Fato R, Miszta P, Filipek S, Caraci F, Giuffrida ML, Andrisano V, Minarini A, Bartolini M, Rosini M
* Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease (460 views)
Acs Med Chem Lett (ISSN: 1948-5875, 1948-5875linking), 2016 Sep 26; 7(12): 1145-1150.
Impact Factor: 3.746
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Palumbo R, Gogliettino M, Cocca E, Iannitti R, Sandomenico A, Ruvo M, Balestrieri M, Rossi M, Palmieri G
* APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome (341 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2016 Sep 23; 17(10): N/D-N/D.
Impact Factor: 3.226
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Soprano M, Sorriento D, Rusciano MR, Maione AS, Limite G, Forestieri P, D'Angelo D, D'Alessio M, Campiglia P, Formisano P, Iaccarino G, Bianco R, Illario M
* Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells (249 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2016 Jun 9; 11(6): e0155970-e0155970.
Impact Factor: 2.806
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Magri A, Di Rosa MC, Tomasello MF, Guarino F, Reina S, Messina A, De Pinto V
* Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes (366 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2016 Mar 4; 1857(6): 789-798.
Impact Factor: 4.932
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Ciccarelli M, Sorriento D, Coscioni E, Iaccarino G, Santulli G
* Adrenergic Receptors (262 views)
Endocrinol Of The Heart In Health And Dis (ISSN: 9780-1280311249780128031117), 2016; N/D: 285-315.
Impact Factor: 0
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De Rosa V, Iommelli F, Monti M, Fonti R, Votta G, Stoppelli MP, Del Vecchio S
* Reversal of Warburg Effect and Reactivation of Oxidative Phosphorylation by Differential Inhibition of EGFR Signaling Pathways in Non-Small Cell Lung Cancer (653 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2015 Nov 15; 21(22): 5110-5120.
Impact Factor: 8.738
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Guardiani C, Scorciapino MA, Amodeo GF, Grdadolnik J, Pappalardo G, De Pinto V, Ceccarelli M, Casu M
* The N-Terminal Peptides of the Three Human Isoforms of the Mitochondrial Voltage-Dependent Anion Channel Have Different Helical Propensities (462 views)
Biochemistry (ISSN: 0006-2960, 1520-4995), 2015 Sep 15; 54(36): 5646-5656.
Impact Factor: 2.876
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Forestier A, Douki T, De Rosa V, Beal D, Rachidi W
* Combination of Abeta Secretion and Oxidative Stress in an Alzheimer-Like Cell Line Leads to the Over-Expression of the Nucleotide Excision Repair Proteins DDB2 and XPC (353 views)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067linking), 2015 Jul 30; 16(8): 17422-17444.
Impact Factor: 3.257
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Sorriento D, Del Giudice C, Bertamino A, Ciccarelli M, Gomez-Monterrey I, Campiglia P, Novellino E, Illario M, Trimarco B, De Luca N, Iaccarino G
* New small molecules, ISA27 and SM13, inhibit tumour growth inducing mitochondrial effects of p53 (376 views)
Br J Cancer (ISSN: 0007-0920, 0007-0920print, 0007-0920linking), 2015 Jan 6; 112(1): 77-85.
Impact Factor: 5.569
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Hangen E, Féraud O, Lachkar S, Mou H, Doti N, Fimia GM, Lam N-V, Zhu C, Godin I, Muller K, Chatzi A, Nuebel E, Ciccosanti F, Flamant S, Bénit P, Perfettini J-L, Sauvat A, Bennaceur-Griscelli A, Ser-Le Roux K, Gonin P, Tokatlidis K, Rustin P, Piacentini M, Ruvo M, Blomgren K, Kroemer G, Modjtahedi N
* Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis (521 views)
Mol Cell (ISSN: 1097-2765, 1097-4164), 2015; 58(6): 1001-1014.
Impact Factor: 13.958
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Gargiulo S, Petretta MP, Greco A, Panico M, Larobina M, Gramanzini M, Schiattarella GG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart (434 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2014 Sep 8; 14(1): 98-98.
Impact Factor: 1.878
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Oppermann S, Schrader FC, Elsasser K, Dolga AM, Kraus AL, Doti N, Wegscheid-Gerlach C, Schlitzer M, Culmsee C
* Novel N-Phenyl-Substituted Thiazolidinediones Protect Neural Cells against Glutamate- and tBid-Induced Toxicity (578 views)
J Pharmacol Exp Ther (ISSN: 0022-3565, 1521-0103), 2014 Sep; 350(2): 273-289.
Impact Factor: 3.972
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Tomasello MF, Sinopoli A, Attanasio F, Giuffrida ML, Campagna T, Milardi D, Pappalardo G
* Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides (1059 views)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2014 Jun 23; 81: 442-455.
Impact Factor: 3.447
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Carriero MV, Bifulco K, Minopoli M, Lista L, Maglio O, Mele L, Di Carluccio G, De Rosa M, Pavone V
* UPARANT: a urokinase receptor-derived peptide inhibitor of VEGF-driven angiogenesis with enhanced stability and in vitro and in vivo potency (467 views)
Mol Cancer Ther (ISSN: 1535-7163, 1538-8514electronic), 2014 May; 13(5): 1092-1104.
Impact Factor: 5.683
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Sorriento D, Ciccarelli M, Santulli G, Illario M, Trimarco B, Iaccarino G
* Trafficking GRK2: Cellular and Metabolic consequences of GRK2 subcellular localization (251 views)
Transl Med Unisa (ISSN: 2239-9747electronic, 2239-9747linking), 2014 Apr 8; 10: 3-7.
Impact Factor: 2.256
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De Chiara L, Fagoonee S, Ranghino A, Bruno S, Camussi G, Tolosano E, Silengo L, Altruda F
* Renal cells from spermatogonial germline stem cells protect against kidney injury (354 views)
J Am Soc Nephrol (ISSN: 1046-6673), 2014 Feb; 25(2): 316-328.
Impact Factor: 9.343
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Giuffrida ML, Rizzarelli E, Tomaselli GA, Satriano C, Trusso Sfrazzetto G
* A novel fully water-soluble Cu(i) probe for fluorescence live cell imaging (373 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2014; 50(69): 9835-9838.
Impact Factor: 6.834
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine and Cognitive Deficits (171 views)
Diet And Nutr In Dement And Cogn Decline (ISSN: 9780-1240793979780124078246), 2014; N/D: 973-982.
Impact Factor: 0
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Sorriento D, Pascale AV, Finelli R, Carillo AL, Annunziata R, Trimarco B, Iaccarino G
* Targeting mitochondria as therapeutic strategy for metabolic disorders (571 views)
Sci World J The Scientific World Journal (ISSN: 1537-744x), 2014; 2014: N/D-N/D.
Impact Factor: 1.219
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Bergamo P, Cocca E, Palumbo R, Gogliettino M, Rossi M, Palmieri G
* RedOx status, proteasome and APEH: Insights into anticancer mechanisms of t10, c12-conjugated linoleic acid isomer on A375 melanoma cells (716 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2013 Nov 19; 8(11): N/D-N/D.
Impact Factor: 3.534
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Savi L, Ribaldone DG, Fagoonee S, Pellicano R
* Is Helicobacter pylori the infectious trigger for headache?: A review (246 views)
Infect Disord Drug Targets (ISSN: 2212-3989electronic, 1871-5265linking), 2013 Oct; 13(5): 313-317.
Impact Factor: 0
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Perrino C, Schiattarella GG, Sannino A, Pironti G, Petretta MP, Cannavo A, Gargiulo G, Ilardi F, Magliulo F, Franzone A, Carotenuto G, Serino F, Altobelli GG, Cimini V, Cuocolo A, Lombardi A, Goglia F, Indolfi C, Trimarco B, Esposito G
* Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure (428 views)
J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2013 May 20; 2(3): e000086-e000086.
Impact Factor: 2.882
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Dolga AM, Netter MF, Perocchi F, Doti N, Meissner L, Tobaben S, Grohm J, Zischka H, Plesnila N, Decher N, Culmsee C
* Mitochondrial Small Conductance SK2 Channels Prevent Glutamate-induced Oxytosis and Mitochondrial Dysfunction (535 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2013 Apr 12; 288(15): 10792-10804.
Impact Factor: 4.6
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Galdiero S, Falanga A, Tarallo R, Russo L, Galdiero E, Cantisani M, Morelli G, Galdiero M
* Peptide inhibitors against herpes simplex virus infections (888 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Mar; 19(3): 148-158.
Impact Factor: 1.862
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Ciccarelli M, Sorriento D, Franco A, Fusco A, Del Giudice C, Annunziata R, Cipolletta E, Monti MG, Dorn GW, Trimarco B, Iaccarino G
* Endothelial G protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species (461 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 2013; 33(10): 2415-2424.
Impact Factor: 5.533
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Del Giudice R, Monti DM, Truppo E, Arciello A, Supuran CT, De Simone G, Monti SM
* Human Carbonic Anhydrase Vii Protects Cells From Oxidative Damage (366 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1431-1673, 1437-4315), 2013; 394(10): 1343-1348.
Impact Factor: 2.689
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Sorriento D, Fusco A, Ciccarelli M, Rungi A, Anastasio A, Carillo A, Dorn II GW, Trimarco B, Iaccarino G
* Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages (385 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013; 587(21): 3487-3494.
Impact Factor: 3.341
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Forestier A, Douki T, Sauvaigo S, De Rosa V, Demeilliers C, Rachidi W
* Alzheimer's disease-associated neurotoxic peptide amyloid-beta impairs base excision repair in human neuroblastoma cells (460 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2012 Nov 13; 13(11): 14766-14787.
Impact Factor: 2.464
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Bellia F, Vecchio G, Rizzarelli E
* Carnosine derivatives: new multifunctional drug-like molecules (549 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Jul; 43(1): 153-163.
Impact Factor: 3.914
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Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (3606 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
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Sandomenico A, Russo A, Palmieri G, Bergamo P, Gogliettino M, Falcigno L, Ruvo M
* Small peptide inhibitors of acetyl-peptide hydrolase having an uncommon mechanism of inhibition and a stable bent conformation (520 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2012 Mar 8; 55(5): 2102-2111.
Impact Factor: 5.614
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Truppo E, Supuran CT, Sandomenico A, Vullo D, Innocenti A, Di Fiore A, Alterio V, De Simone G, Monti SM
* Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors (384 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2012 Feb 15; 22(4): 1560-1564.
Impact Factor: 2.338
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (550 views)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Fusco A, Santulli G, Sorriento D, Cipolletta E, Garbi C, Dorn GW, Trimarco B, Feliciello A, Iaccarino G
* Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis (422 views)
Cell Signal (ISSN: 0898-6568), 2012; 24(2): 468-475.
Impact Factor: 4.304
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Calabrese V, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ
* Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity (880 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 279-304.
Impact Factor: 9.97
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Bellia F, Vecchio G, Cuzzocrea S, Calabrese V, Rizzarelli E
* Neuroprotective features of carnosine in oxidative driven diseases (424 views)
Molecular Aspects Of Medicine (ISSN: 1872-9452, 0098-2997), 2011 Sep; 32(4-6): 258-266.
Impact Factor: 9.97
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Corona C, Frazzini V, Silvestri E, Lattanzio R, La Sorda R, Piantelli M, Canzoniero LM, Ciavardelli D, Rizzarelli E, Sensi SL
* Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice (553 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2011 Mar 15; 6(3): e17971-e17971.
Impact Factor: 4.092
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Rachidi W, De Rosa V
Selenium protects against the cytotoxic and genotoxic effects of oxidative stress both as an anti-oxidant and by stimulating DNA damage repair (306 views)
Bulletin Du Cancer (ISSN: 0007-4551), 2011 Mar; 98: N/D-N/D.
Impact Factor: 0.672
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Lanza V, Bellia F, D'Agata R, Grasso G, Rizzarelli E, Vecchio G
* New glycoside derivatives of carnosine and analogs resistant to carnosinase hydrolysis: synthesis and characterization of their copper(II) complexes (402 views)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2011 Feb; 105(2): 181-188.
Impact Factor: 3.354
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Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (429 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2010 Dec; 35(12): 2144-2153.
Impact Factor: 2.608
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Perrino C, Feliciello A, Schiattarella GG, Esposito G, Guerriero R, Zaccaro L, Del Gatto A, Saviano M, Garbi C, Carangi R, Di Lorenzo E, Donato G, Indolfi C, Avvedimento VE, Chiariello M
* AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress (433 views)
Cardiovascular Research (ISSN: 0008-6363), 2010 Oct; 88(1): 101-110.
Impact Factor: 6.051
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (554 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
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Castellano I, Merlino A, Rossi M, La Cara F
* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (613 views)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
Impact Factor: 3.787
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De Rosa V, Diamond A, Favier A, Douki T, Rachidi W
* Effect of selenium on lethal and genotoxic properties of oxidative stress (206 views)
Bulletin Du Cancer (ISSN: 0007-4551), 2010 Mar; 97: N/D-N/D.
Impact Factor: 0.887
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Bellia F, Calabrese V, Guarino F, Cavallaro M, Cornelius C, De Pinto V, Rizzarelli E
* Carnosinase levels in aging brain: redox state induction and cellular stress response (430 views)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2759-2775.
Impact Factor: 7.581
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Lettieri A, Salvatore M
* Molecular imaging of drug resistance in cancer (438 views)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Mar; 21(1): 31-36.
Impact Factor: 0.268
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De Rosa V, Alan D, Alain F, Thierry D, Walid R
* The anticancer effect of selenium: study of its role in DNA repair activity and resistance to oxidative stress (250 views)
Bulletin Du Cancer (ISSN: 0007-4551), 2009 Mar; 96: N/D-N/D.
Impact Factor: 0.792
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Calabrese V, Cornelius C, Mancuso C, Barone E, Calafato S, Bates T, Rizzarelli E, Kostova AT
* Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases (1144 views)
Frontiers In Bioscience (ISSN: 1093-4715, 1093-9946), 2009 Jan 1; 14: 376-397.
Impact Factor: 3.736
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Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E
* Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity (1232 views)
Neurochemical Research (ISSN: 1573-6903, 0364-3190), 2008 Dec; 33(12): 2444-2471.
Impact Factor: 2.26
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Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti
* The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders (388 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2008 Dec; 33(12): 2401-2406.
Impact Factor: 2.26
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Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (550 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
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Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
* Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type (537 views)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2008 Aug 15; 14(16): 5209-5219.
Impact Factor: 6.488
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Supuran CT, Di Fiore A, De Simone G
* Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity (562 views)
Expert Opin Emerg Drugsexpert Opinion On Emerging Drugs (ISSN: 1472-8214), 2008 Jun; 13(2): 383-392.
Impact Factor: 3.08
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Limauro D, Pedone E, Galdi I, Bartolucci S
* Peroxiredoxins as cellular guardians in Sulfolobus solfataricus - characterization of Bcp1, Bcp3 and Bcp4 (366 views)
Febs Journal (ISSN: 1742-464x), 2008 May; 275(9): 2067-2077.
Impact Factor: 3.139
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Caraci F, Battaglia G, Busceti C, Biagioni F, Mastroiacovo F, Bosco P, Drago F, Nicoletti F, Sortino MA, Copani A
* TGF-β1 protects against Aβ-neurotoxicity via the phosphatidylinositol-3-kinase pathway (408 views)
Neurobiology Of Disease (ISSN: 0969-9961), 2008 May; 30(2): 234-242.
Impact Factor: 4.852
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Atlante A, Amadoro G, Bobba A, de Bari L, Corsetti V, Pappalardo G, Marra E, Calissano P, Passarella S
* A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator (507 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 0006-3002linking), 2008; 1777(10): 1289-1300.
Impact Factor: 4.447
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (407 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
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Vitale RM, Pedone C, Amodeo P, Antel J, Wurl M, Scozzafava A, Supuran CT, De Simone G
* Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA (335 views)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 1464-3391electronic), 2007 Jun 15; 15(12): 4152-4158.
Impact Factor: 2.662
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Cuzzocrea S, Genovese T, Failla M, Vecchio G, Fruciano M, Mazzon E, Di Paola R, Muià C, La Rosa C, Crimi N, Rizzarelli E, Vancheri C
* Protective effect of orally administered carnosine on bleomycin-induced lung injury (575 views)
Am J Physiol Lung Cell Mol Physiol (ISSN: 1040-0605), 2007 May; 292(5): L1095-L1095.
Impact Factor: 4.214
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Galdiero S, Galdiero M, Pedone C
* Beta-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly And Interaction With Lipids (438 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2007 Feb; 8(1): 63-82.
Impact Factor: 3.259
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Ronga L, Palladino P, Costantini S, Facchiano A, Ruvo M, Benedetti E, Ragone R, Rossi F
* Conformational diseases and structure-toxicity relationships: Lessons from prion-derived peptides (553 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2007 Feb; 8(1): 83-90.
Impact Factor: 3.259
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Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (522 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2007 Jan 12; 282(2): 831-835.
Impact Factor: 5.581
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Pedone E, Limauro D, D'Alterio R, Rossi M, Bartolucci S
* Characterization of a multifunctional protein disulfide oxidoreductase from Sulfolobus solfataricus (328 views)
Febs Journal (ISSN: 1742-464x), 2006 Dec; 273(23): 5407-5420.
Impact Factor: 3.033
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Palumbo R, Capasso D, Brescia F, Mita P, Sarti M, Bersani F, Scarfi MR
* Effects on apoptosis and reactive oxygen species formation by Jurkat cells exposed to 50 Hz electromagnetic fields (596 views)
Bioelectromagnetics (ISSN: 0197-8462), 2006 Feb; 27(2): 159-162.
Impact Factor: 1.514
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Limauro D, Pedone E, Pirone L, Bartolucci S
* Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress (362 views)
Febs Journal (ISSN: 1742-464x), 2006 Feb; 273(4): 721-731.
Impact Factor: 3.033
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Calabrese V, Colombrita C, Guagliano E, Sapienza M, Ravagna A, Cardile V, Scapagnini G, Santoro AM, Mangiameli A, Butterfield DA, Giuffrida Stella AM, Rizzarelli E
* Protective effect of carnosine during nitrosative stress in astroglial cell cultures (379 views)
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2005 Jun; 30(6-7): 797-807.
Impact Factor: 2.187
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De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, Scozzafava A, Wurl M, Supuran CT
* Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies (420 views)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 May 2; 15(9): 2315-2320.
Impact Factor: 2.478
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Pedone E, Bartolucci S, Fiorentino G
* Sensing and adapting to environmental stress: The Archaeal tactic (327 views)
Frontiers In Bioscience (ISSN: 1093-9946, 1093-4715), 2004 Sep 1; 9: 2909-2926.
Impact Factor: 3.226
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De Capua A, Del Gatto A, Zaccaro L, Saviano G, Carlucci A, Livigni A, Gedressi C, Tancredi T, Pedone C, Saviano M
* A synthetic peptide reproducing the mitochondrial targeting motif of AKAP121: A conformational study (475 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 459-466.
Impact Factor: 2.863
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Saviano M, Zaccaro L, Benedetti E, Pedone C, Del Gatto A, Feliciello A, Affaiatati A, Avvedimento EV
* Development of peptides able to modulate the interaction of AKAP121 with mitochondria (418 views)
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (527 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Tabbì G, Cassino C, Cavigiolio G, Colangelo D, Ghiglia A, Viano I, Osella D
* Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process (642 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2002 Dec 19; 45(26): 5786-5796.
Impact Factor: 4.566
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Cardone L, de Cristofaro T, Affaitati A, Garbi C, Ginsberg MD, Saviano M, Varrone S, Rubin CS, Gottesman ME, Avvedimento EV, Feliciello A
* A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs (654 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2002 Jul 12; 320(3): 663-675.
Impact Factor: 5.359
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Tedesco I, Russo GL, Nazzaro F, Russo M, Palumbo R
* Antioxidant effect of red wine anthocyanins in normal and catalase-inactive human erythrocytes (883 views)
J Nutr Biochem (ISSN: 0955-2863), 2001 Sep; 12(9): 505-511.
Impact Factor: 1.039
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Ogawa R, Pacelli R, Espey MG, Miranda KM, Friedman N, Kim SM, Cox G, Mitchell JB, Wink DA, Russo A
* Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and no donors: Insights into listeriocidal activity of oxidative and nitrosative stress (688 views)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2001 Feb 1; 30(3): 268-276.
Impact Factor: 5.082
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Tedesco I, Russo M, Russo P, Iacomino G, Russo GL, Carraturo A, Faruolo C, Moio L, Palumbo R
Antioxidant effect of red wine polyphenols on red blood cells (564 views)
J Nutr Biochem (ISSN: 0955-2863), 2000 Feb; 11(2): 114-119.
Impact Factor: 1.083
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Russo M, Palumbo R, Tedesco I, Mazzarella G, Russo P, Iacomino G, Russo GL
Quercetin and anti-CD95(Fas/Apo1) enhance apoptosis in HPB-ALL cell line (402 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 1999 Dec 3; 462(3): 322-328.
Impact Factor: 3.72
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Wink DA, Vodovotz Y, Grisham MB, DeGraff W, Cook JC, Pacelli R, Krishna M, Mitchell JB
Antioxidant effects of nitric oxide (351 views)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 1998; 301: 413-424.
Impact Factor: 2.823
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Wink DA, Cook JA, Kim SY, Vodovotz Y, Pacelli R, Krishna MC, Russo A, Mitchell JB, Jourd'heuil D, Miles AM, Grisham MB
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates (336 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 1997 Apr 25; 272(17): 11147-11151.
Impact Factor: 6.963
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Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB
Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms (691 views)
Current Topics In Cellular Regulation (ISSN: 0070-2137), 1996; 34: 159-187.
Impact Factor: 4.375
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Wink DA, Cook JA, Pacelli R, Liebmann J, Krishna MC, Mitchell JB
Nitric oxide (NO) protects against cellular damage by reactive oxygen species (526 views)
Toxicology Letters (ISSN: 0378-4274), 1995 Dec; 82-3: 221-226.
Impact Factor: 1.128
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (587 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
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Condorelli G, Costanzo LL, De Guidi G, Giuffrida S, Rizzarelli E, Vecchio G
INHIBITION OF PHOTOHEMOLYSIS BY COPPER(II) COMPLEXES WITH SOD-LIKE ACTIVITY (489 views)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1994 Jun; 54(4): 257-265.
Impact Factor: 1.342
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102 Records (94 excluding Abstracts).
Total impact factor: 385.934 (355.332 excluding Abstracts).
Total 5 year impact factor: 369.232 (336.511 excluding Abstracts).
Total impact factor: 385.934 (355.332 excluding Abstracts).
Total 5 year impact factor: 369.232 (336.511 excluding Abstracts).
562 views. Last view on Saturday 28 January 2023, 4:17:27
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