Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells(429 views) Severino V, Alessio N, Farina A, Sandomenico A, Cipollaro M, Peluso G, Galderisi U, Chambery A
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2013 Nov 7; 4(11): e911-e911.
Keywords: Igfbp4, Mass Spectrometry, Mesenchymal Stem Cells, Secretome, Senescence, Somatomedin Binding Protein, Unclassified Drug, Insulin Like Growth Factor Binding Protein Related Protein 1, Insulin-Like Growth Factor Binding Protein-Related Protein 1, Apoptosis, Article, Cell Growth, Cell Maturation, Controlled Study, Culture Medium, Cytology, Dna Damage, Human, Human Cell, Nucleotide Sequence, Phenotype, Pleiotropy, Priority Journal, Western Blotting, Biology, Cell Aging, Cell Culture, Cell Differentiation, Cell Proliferation, Drug Effect, Genetics, Immunohistochemistry, Liquid Chromatography, Metabolism, Tandem Mass Spectrometry, Computational Biology, Conditioned, Apoptosis Drug Effects, Cell Aging Drug Effects Genetics, Cell Differentiation Drug Effects Genetics, Cell Proliferation Drug Effects, Conditioned Pharmacology, Insulin-Like Growth Factor Binding Protein 4 Genetics Metabolism Pharmacology, Insulin-Like Growth Factor Binding Proteins Genetics Metabolism Pharmacology,
Affiliations: *** IBB - CNR ***
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Caserta I-81100, Italy
Institute of Biostructures and Bioimaging-IBB, CNR, Napoli, Italy
Centro Interuniversitario di Ricerca sui Peptidi Bioattivi-CIRPEB, Napoli, Italy
Department of Experimental Medicine, Biotechnology and Molecular Biology Section, Second University of Naples, Napoli I-80138, Italy
Biomedical Proteomics Research Group, Department of Bioinformatics and Structural Biology, Geneva University, Geneva, Switzerland
Institute of Protein Biochemistry and Bioresources-IBP, CNR, Napoli, Italy
Institute of Biosciences and Bioresources-IBBR, CNR, Napoli, Italy
Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, Temple University, Philadelphia, PA, United States
Genome and Stem Cell Center-GENKOK, Erciyes University, Kayseri, Turkey
1] Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Caserta, Italy [2] Institute of Biostructures and Bioimaging-IBB, CNR, Napoli, Italy [3] Centro Interuniversitario di Ricerca sui Peptidi Bioattivi-CIRPEB, Napoli, Italy.
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Hsiao, S. T., Asgari, A., Lokmic, Z., Sinclair, R., Dusting, G. J., Lim, S. Y., Comparative analysis of paracrine factor expression in human adult mesenchymal stem cells derived from bone marrow, adipose, and dermal tissue (2012) Stem cells Dev, 21, pp. 2189-2203
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Pollina, E. A., Brunet, A., Epigenetic regulation of aging stem cells (2011) Oncogene, 30, pp. 3105-3126
Lombard, D. B., Chua, K. F., Mostoslavsky, R., Franco, S., Gostissa, M., Alt, F. W., DNA repair, genome stability, and aging (2005) Cell, 120, pp. 497-512
Roos, W. P., Kaina, B., DNA damage-induced cell death by apoptosis (2006) Trends Mol Med, 12, pp. 440-450
Zhao, C. Q., Wang, L. M., Jiang, L. S., Dai, L. Y., The cell biology of intervertebral disc aging and degeneration (2007) Ageing Res Rev, 6, pp. 247-261
Yang, K. E., Kwon, J., Rhim, J. H., Choi, J. S., Kim, S. I., Lee, S. H., Differential expression of extracellular matrix proteins in senescent and young human fibroblasts: A comparative proteomics and microarray study (2011) Mol Cells, 32, pp. 99-106
Holt, S. E., Aisner, D. L., Baur, J., Tesmer, V. M., Dy, M., Ouellette, M., Functional requirement of p23 and Hsp90 in telomerase complexes (1999) Genes Dev, 13, pp. 817-826
Kim, K. S., Kim, M. S., Seu, Y. B., Chung, H. Y., Kim, J. H., Kim, J. R., Regulation of replicative senescence by insulin-like growth factor-binding protein 3 in human umbilical vein endothelial cells (2007) Aging Cell, 6, pp. 535-545
Elzi, D. J., Lai, Y., Song, M., Hakala, K., Weintraub, S. T., Shiio, Y., Plasminogen activator inhibitor 1-insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence (2012) Proc Natl Acad Sci USA, 109, pp. 12052-12057
Kim, K. S., Seu, Y. B., Baek, S. H., Kim, M. J., Kim, K. J., Kim, J. H., Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism (2007) Mol Biol Cell, 18, pp. 4543-4552
Mueller, L. N., Rinner, O., Schmidt, A., Letarte, S., Bodenmiller, B., Brusniak, M. Y., SuperHirn-A novel tool for high resolution LC-MS-based peptide/protein profiling (2007) Proteomics, 7, pp. 3470-3480
Bendtsen, J. D., Nielsen, H., Von Heijne, G., Brunak, S., Improved prediction of signal peptides: SignalP 3. 0 (2004) J Mol Biol, 340, pp. 783-795
Bendtsen, J. D., Jensen, L. J., Blom, N., Von Heijne, G., Brunak, S., Feature-based prediction of non-classical and leaderless protein secretion (2004) Protein Eng Des Sel, 17, pp. 349-356
Gary, R. K., Kindell, S. M., Quantitative assay of senescence-Associated beta-galactosidase activity in mammalian cell extracts (2005) Anal Biochem, 343, pp. 329-334
Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(257 views) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 ViewExport to BibTeXExport to EndNote