CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS(339 views) Ferrara LA, Mancini M, Iannuzzi R, Marotta T, Gaeta I, Pasanisi F, Postiglione A, Guida L
Affiliations: IIMMD, Medical School, Federico II University, Via S Pansini 5, 80131 Naples, Italy
References: Not available.
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS
Background and Purpose The recent development of noninvasive techniques for the evaluation of the carotid arteries has focused attention on the study of arterial wall thickness to identify early lesions of vessels in patients at high risk for atherosclerosis, such as those with hypercholesterolemia, diabetes mellitus, and hypertension. Methods In a sample of 70 hypertensive patients without clinical evidence of target organ damage, we showed a thickening of the intimal plus medial layers compared with age- and sex-matched normotensive control subjects. In this sample we also studied the diameter of the carotid arteries by ultrasound imaging, and we studied how velocities in common carotid, internal carotid, and middle cerebral arteries by Doppler technique. Pulsatility and resistance indexes were calculated. Results Absolute values of the carotid diameter were similar in the two groups (6.3+/-0.7 versus 6.0+/-0.8 mm); however, the ratio of diameter to blood pressure was significantly reduced in hypertensive compared with normotensive subjects (5.3+/-0.7 versus 6.5+/-0.8; P
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS
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