Factors affecting lipoprotein lipase in hypertensive patients (375 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
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Paper type: Journal Article,
Impact factor: 1.681, 5-year impact factor: 2.583
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029076878&partnerID=40&md5=3cc48e2e8a2ff3a6d59921900286daff
Keywords: Adrenalin, Beta Adrenergic Receptor Blocking Agent, High Density Lipoprotein Cholesterol, Hydralazine, Insulin, Lipoprotein Lipase, Liver Triacylglycerol Lipase, Noradrenalin, Placebo, Prazosin, Propranolol, Vasodilator Agent, Adult, Aorta Flow, Article, Blood Pressure, Clinical Article, Clinical Trial, Controlled Clinical Trial, Controlled Study, Double Blind Procedure, Enzyme Activity, Female, Heart Rate, Hemodynamics, Human, Hypertension, Lipid Metabolism, Oral Drug Administration, Priority Journal, Randomized Controlled Trial, Drug Therapy, Combination, Middle Aged,
Affiliations:
Institute of Internal Medicine and Metabolic Diseases, Federico II University, Naples, Italy
Institute of Pharmacology and Toxicology, 2nd University of Naples, Naples, Italy
References:
Reader, Bauer, Doyle, The Australian Therapeutic Trial in Mild Hypertension (1980) Lancet, 1, pp. 1261-127
Assmann, The Prospective Cardiovascular Münster (PROCAM) Study: Prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to coronary heart disease (1988) Am Heart J, 116, pp. 1713-1724
Stamler, Westworth, Neaton, Factor Intervention Trial Research Group: Is the relation between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? (1986) Findings in 356222 primary screenes of the Multiple Risk Factor Intervention Trial (MRFIT), 256, pp. 2823-2828. , ed 2, JAMA
Laurenzi, Mancini, Menotti, Multiple risk factors in hypertension Results from the Gubbio study (1990) Journal of Hypertension, 8, pp. S7-S12. , suppl 1
Reaven, Role of insulin resistance in human disease (1988) Diabetes, 37, pp. 1595-1607
Ferrannini, Metabolic abnormalities of hypertension (1991) A lesson in complexity, 18, pp. 636-639. , ed 2, Hypertension
Borensztajn, (1987) Lipoprotein Lipase, , Evener, Chicago, IL
Foster, Insulin resistance—A secret killer? (1989) N Engl J Med, 320, pp. 733-734
Slater, Insulin resistance and hypertension (1991) Hypertension, 18, pp. I108-I114. , (suppl)
Pollare, Vessby, Lithell, Lipoprotein lipase activity in skeletal muscle is related to insulin sensitivity (1991) Arterioscler Thromb, 11, pp. 1192-1203
Sacks, Dzau, Adrenergic effects on plasma lipoprotein metabolism: Speculation on mechanism of action (1986) Am J Med, 80, pp. 71-81. , suppl 2A
Weidmann, Uehlinger, Gerber, Antihypertensive treatment and serum lipoproteins (1985) J Hypertens, 3, pp. 297-306
Thaulow, Nitter-Hauge, Antihypertensive therapy and blood lipids: Alpha blockers (1990) Scand J Clin Lab Invest, 50, pp. 45-48. , Suppl 99
Rössner, Studies on an intravenous fat tolerance test (1974) Methodological, experimental and clinical experience with Intralipid, pp. 1-24. , ed 2, Acta Med Scand, [Suppl 564]
Hyelm, Enzymatic determination of hexoses in blood and urine (1966) Scand J Invest, 18, pp. 85-98. , Suppl 192
Siedel, Schlumberger, Klose, Improved reagent for enzymatic determination of serum cholesterol (1981) J Clin Chem Clin Biochem, 19, pp. 838-839
Wahlefeld, Triglycerides determination after enzymatic hydrolysis (1974) Methods of Enzymatic Analysis, 4, pp. 1831-1974. , ed 2, HU Bergemeyer, Academic, New York, NY
Kostner, Enzymatic determination of cholesterol in high density lipoprotein fractions prepared by polyanion precipitation (1976) Clin Chem, 22, pp. 695-698
De Lalla, Gofman, Ultracentrifugal analysis for plasma lipoproteins (1954) Methods of Biochemical Analysis, 1, pp. 459-478. , ed 2, P Glick, Interscience, New York, NY
Marcovina, Di Cola, Rapetto, Development of a radial immunodiffusion technique employing monoclonal antibodies for apoprotein B determination in human plasma (1985) Clin Chim Acta, 147, pp. 117-125
Debuquois, Aurbach, Use of polyethylene glycol to separate free and antibody bound peptide hormones in radioimmunoassay (1971) J Clin Endocrinol Metab, 33, pp. 732-738
Nilsson-Ehle, Measurements of lipoprotein lipase activity (1987) Lipoprotein Lipase, pp. 59-77. , J Borensztajn, Evener, Chicago, IL
Foti, Kimura, De Quattro, Liquid-chromatographic measurement of catecholamines in plasma and urine (1987) Clin Chem, 33, pp. 2209-2213
Coats, Doppler ultrasonic measurement of cardiac output: Reproducibility and validation (1990) Eur Heart J, 11, pp. 49-66. , suppl 1
Nie, Hull, Jenkins, (1975) Statistical Package for Social Sciences, , ed 2, McGraw-Hill, New York, NY
Patsch, Prasad, Gotto, Jr, High density lipoprotein2 (1987) Relationship of the plasma levels of this lipoprotein species to its composition, to the magnitude of postprandial lipemia, and to the activities of lipoprotein lipase and hepatic lipase, 80, pp. 341-347. , ed 2, J Clin Invest
Levy, Deckelbaum, Thibault, In vitro remodelling of plasma lipoproteins in whole plasma by lipoprotein lipase in primary and secondary hypertriglyceridaemia (1990) Eur J Clin Invest, 20, pp. 422-431
Marotta, Ferrara, Pasanisi, Enhancement of exogenous triglyceride removal following calcium channel blockade (1989) Artery, 16, pp. 312-326
Eckel, Lipoprotein lipase (1989) A multifunctional enzyme relevant to common metabolic diseases, 320, pp. 1060-1068. , ed 2, N Engl J Med
Ashby, Bennett, Spencer, Post-translational regulation of lipoprotein lipase activity in adipose tissue (1978) Biochem J, 176, pp. 865-872
Farese, Yost, Eckel, Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans (1991) Metabolism, 40, pp. 214-216
Zavaroni, Bonora, Pagliara, Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance (1989) N Engl J Med, 320, pp. 702-706
Zavaroni, Dall'Aglio, Alpi, Evidence for an independent relationship between plasma insulin and concentration of high density lipoprotein cholesterol and triglyceride (1985) Atherosclerosis, 55, pp. 259-266
Stalder, Pometta, Suenram, Relationship between plasma insulin levels and high density lipoprotein cholesterol levels in healthy men (1981) Diabetologia, 21, pp. 544-548
Capaldo, Rivellese, Santoro, Relationship between insulin response to intravenous glucose and plasma lipoproteins in healthy men (1985) Artery, 13, pp. 108-126
Laakso, How good a marker is insulin level for insulin resistance? (1993) Am J Epidemiol, 137, pp. 959-965
Frayn, Insulin resistance and lipid metabolism (1993) Curr Opin Lipidol, 4, pp. 197-204
Miesenböck, Patsch, Postprandial hyperlipidemia The search for the atherogenic lipoprotein (1992) Current Opinion in Lipidology, 3, pp. 196-201
Taskinen, Kuusi, Helve, Insulin therapy induces antiatherogenic changes of serum lipoproteins in noninsulin-dependent diabetes (1988) Arteriosclerosis, 8, pp. 168-177
Tuck, Obesity, the sympathetic nervous system, and essential hypertension (1992) Hypertension, 19, pp. I67-I77. , (suppl)
Mathias, Role of sympathetic efferent nerves in blood pressure regulation and in hypertension (1991) Hypertension, 18, pp. 22-30. , suppl 3
Rowe, Young, Minaker, Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man (1981) Diabetes, 30, pp. 219-225
Ferrara, Di Marino, Russo, Doxazosin and captopril in mildly hypercholesterolemic hypertensive patients (1993) The Doxazosin-Captopril in Hypercholesterolemic Hypertensives Study, 21, pp. 97-104. , ed 2, Hypertension
Medical Research Council Working Party, MRC trial of treatment of mild hypertension Principal results (1985) BMJ, 291, pp. 97-104
Mancini, Ferrara, Strazzullo, Metabolic disturbances and antihypertensive therapy (1991) J Hypertens, 9, pp. S47-S50. , suppl 3
Maling, Ferrara, Mucklow, Blood pressure and plasma noradrenaline during single high-dose beta adrenoceptor blockade (1979) Eur J Clin Pharmacol, 15, pp. 375-379
Day, Metcalfe, Simpson, Adrenergic mechanism in control of plasma lipid concentrations (1982) Br Med J, 284, pp. 1145-1148
Murphy, Sugrue, Trayner, Effects of short term beta adrenoreceptor blockade on serum lipids and lipoproteins in patients with hypertension or coronary artery disease (1984) Br Heart J, 51, pp. 589-594
R ssner, Studies on an intravenous fat tolerance test (1974) Methodological, experimental and clinical experience with Intralipid, pp. 1-24. , ed 2, Acta Med Scand, [Suppl 564]
Miesenb ck, Patsch, Postprandial hyperlipidemia The search for the atherogenic lipoprotein (1992) Current Opinion in Lipidology, 3, pp. 196-201
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 1.681, 5-year impact factor: 2.583
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0029076878&partnerID=40&md5=3cc48e2e8a2ff3a6d59921900286daff
Keywords: Adrenalin, Beta Adrenergic Receptor Blocking Agent, High Density Lipoprotein Cholesterol, Hydralazine, Insulin, Lipoprotein Lipase, Liver Triacylglycerol Lipase, Noradrenalin, Placebo, Prazosin, Propranolol, Vasodilator Agent, Adult, Aorta Flow, Article, Blood Pressure, Clinical Article, Clinical Trial, Controlled Clinical Trial, Controlled Study, Double Blind Procedure, Enzyme Activity, Female, Heart Rate, Hemodynamics, Human, Hypertension, Lipid Metabolism, Oral Drug Administration, Priority Journal, Randomized Controlled Trial, Drug Therapy, Combination, Middle Aged,
Affiliations:
Institute of Internal Medicine and Metabolic Diseases, Federico II University, Naples, Italy
Institute of Pharmacology and Toxicology, 2nd University of Naples, Naples, Italy
References:
Reader, Bauer, Doyle, The Australian Therapeutic Trial in Mild Hypertension (1980) Lancet, 1, pp. 1261-127
Assmann, The Prospective Cardiovascular Münster (PROCAM) Study: Prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to coronary heart disease (1988) Am Heart J, 116, pp. 1713-1724
Stamler, Westworth, Neaton, Factor Intervention Trial Research Group: Is the relation between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? (1986) Findings in 356222 primary screenes of the Multiple Risk Factor Intervention Trial (MRFIT), 256, pp. 2823-2828. , ed 2, JAMA
Laurenzi, Mancini, Menotti, Multiple risk factors in hypertension Results from the Gubbio study (1990) Journal of Hypertension, 8, pp. S7-S12. , suppl 1
Reaven, Role of insulin resistance in human disease (1988) Diabetes, 37, pp. 1595-1607
Ferrannini, Metabolic abnormalities of hypertension (1991) A lesson in complexity, 18, pp. 636-639. , ed 2, Hypertension
Borensztajn, (1987) Lipoprotein Lipase, , Evener, Chicago, IL
Foster, Insulin resistance—A secret killer? (1989) N Engl J Med, 320, pp. 733-734
Slater, Insulin resistance and hypertension (1991) Hypertension, 18, pp. I108-I114. , (suppl)
Pollare, Vessby, Lithell, Lipoprotein lipase activity in skeletal muscle is related to insulin sensitivity (1991) Arterioscler Thromb, 11, pp. 1192-1203
Sacks, Dzau, Adrenergic effects on plasma lipoprotein metabolism: Speculation on mechanism of action (1986) Am J Med, 80, pp. 71-81. , suppl 2A
Weidmann, Uehlinger, Gerber, Antihypertensive treatment and serum lipoproteins (1985) J Hypertens, 3, pp. 297-306
Thaulow, Nitter-Hauge, Antihypertensive therapy and blood lipids: Alpha blockers (1990) Scand J Clin Lab Invest, 50, pp. 45-48. , Suppl 99
Rössner, Studies on an intravenous fat tolerance test (1974) Methodological, experimental and clinical experience with Intralipid, pp. 1-24. , ed 2, Acta Med Scand, [Suppl 564]
Hyelm, Enzymatic determination of hexoses in blood and urine (1966) Scand J Invest, 18, pp. 85-98. , Suppl 192
Siedel, Schlumberger, Klose, Improved reagent for enzymatic determination of serum cholesterol (1981) J Clin Chem Clin Biochem, 19, pp. 838-839
Wahlefeld, Triglycerides determination after enzymatic hydrolysis (1974) Methods of Enzymatic Analysis, 4, pp. 1831-1974. , ed 2, HU Bergemeyer, Academic, New York, NY
Kostner, Enzymatic determination of cholesterol in high density lipoprotein fractions prepared by polyanion precipitation (1976) Clin Chem, 22, pp. 695-698
De Lalla, Gofman, Ultracentrifugal analysis for plasma lipoproteins (1954) Methods of Biochemical Analysis, 1, pp. 459-478. , ed 2, P Glick, Interscience, New York, NY
Marcovina, Di Cola, Rapetto, Development of a radial immunodiffusion technique employing monoclonal antibodies for apoprotein B determination in human plasma (1985) Clin Chim Acta, 147, pp. 117-125
Debuquois, Aurbach, Use of polyethylene glycol to separate free and antibody bound peptide hormones in radioimmunoassay (1971) J Clin Endocrinol Metab, 33, pp. 732-738
Nilsson-Ehle, Measurements of lipoprotein lipase activity (1987) Lipoprotein Lipase, pp. 59-77. , J Borensztajn, Evener, Chicago, IL
Foti, Kimura, De Quattro, Liquid-chromatographic measurement of catecholamines in plasma and urine (1987) Clin Chem, 33, pp. 2209-2213
Coats, Doppler ultrasonic measurement of cardiac output: Reproducibility and validation (1990) Eur Heart J, 11, pp. 49-66. , suppl 1
Nie, Hull, Jenkins, (1975) Statistical Package for Social Sciences, , ed 2, McGraw-Hill, New York, NY
Patsch, Prasad, Gotto, Jr, High density lipoprotein2 (1987) Relationship of the plasma levels of this lipoprotein species to its composition, to the magnitude of postprandial lipemia, and to the activities of lipoprotein lipase and hepatic lipase, 80, pp. 341-347. , ed 2, J Clin Invest
Levy, Deckelbaum, Thibault, In vitro remodelling of plasma lipoproteins in whole plasma by lipoprotein lipase in primary and secondary hypertriglyceridaemia (1990) Eur J Clin Invest, 20, pp. 422-431
Marotta, Ferrara, Pasanisi, Enhancement of exogenous triglyceride removal following calcium channel blockade (1989) Artery, 16, pp. 312-326
Eckel, Lipoprotein lipase (1989) A multifunctional enzyme relevant to common metabolic diseases, 320, pp. 1060-1068. , ed 2, N Engl J Med
Ashby, Bennett, Spencer, Post-translational regulation of lipoprotein lipase activity in adipose tissue (1978) Biochem J, 176, pp. 865-872
Farese, Yost, Eckel, Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans (1991) Metabolism, 40, pp. 214-216
Zavaroni, Bonora, Pagliara, Risk factors for coronary artery disease in healthy persons with hyperinsulinemia and normal glucose tolerance (1989) N Engl J Med, 320, pp. 702-706
Zavaroni, Dall'Aglio, Alpi, Evidence for an independent relationship between plasma insulin and concentration of high density lipoprotein cholesterol and triglyceride (1985) Atherosclerosis, 55, pp. 259-266
Stalder, Pometta, Suenram, Relationship between plasma insulin levels and high density lipoprotein cholesterol levels in healthy men (1981) Diabetologia, 21, pp. 544-548
Capaldo, Rivellese, Santoro, Relationship between insulin response to intravenous glucose and plasma lipoproteins in healthy men (1985) Artery, 13, pp. 108-126
Laakso, How good a marker is insulin level for insulin resistance? (1993) Am J Epidemiol, 137, pp. 959-965
Frayn, Insulin resistance and lipid metabolism (1993) Curr Opin Lipidol, 4, pp. 197-204
Miesenböck, Patsch, Postprandial hyperlipidemia The search for the atherogenic lipoprotein (1992) Current Opinion in Lipidology, 3, pp. 196-201
Taskinen, Kuusi, Helve, Insulin therapy induces antiatherogenic changes of serum lipoproteins in noninsulin-dependent diabetes (1988) Arteriosclerosis, 8, pp. 168-177
Tuck, Obesity, the sympathetic nervous system, and essential hypertension (1992) Hypertension, 19, pp. I67-I77. , (suppl)
Mathias, Role of sympathetic efferent nerves in blood pressure regulation and in hypertension (1991) Hypertension, 18, pp. 22-30. , suppl 3
Rowe, Young, Minaker, Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man (1981) Diabetes, 30, pp. 219-225
Ferrara, Di Marino, Russo, Doxazosin and captopril in mildly hypercholesterolemic hypertensive patients (1993) The Doxazosin-Captopril in Hypercholesterolemic Hypertensives Study, 21, pp. 97-104. , ed 2, Hypertension
Medical Research Council Working Party, MRC trial of treatment of mild hypertension Principal results (1985) BMJ, 291, pp. 97-104
Mancini, Ferrara, Strazzullo, Metabolic disturbances and antihypertensive therapy (1991) J Hypertens, 9, pp. S47-S50. , suppl 3
Maling, Ferrara, Mucklow, Blood pressure and plasma noradrenaline during single high-dose beta adrenoceptor blockade (1979) Eur J Clin Pharmacol, 15, pp. 375-379
Day, Metcalfe, Simpson, Adrenergic mechanism in control of plasma lipid concentrations (1982) Br Med J, 284, pp. 1145-1148
Murphy, Sugrue, Trayner, Effects of short term beta adrenoreceptor blockade on serum lipids and lipoproteins in patients with hypertension or coronary artery disease (1984) Br Heart J, 51, pp. 589-594
R ssner, Studies on an intravenous fat tolerance test (1974) Methodological, experimental and clinical experience with Intralipid, pp. 1-24. , ed 2, Acta Med Scand, [Suppl 564]
Miesenb ck, Patsch, Postprandial hyperlipidemia The search for the atherogenic lipoprotein (1992) Current Opinion in Lipidology, 3, pp. 196-201
Factors affecting lipoprotein lipase in hypertensive patients
Arterial hypertension is frequently associated with serum lipid abnormalities. Lipid metabolism can also be affected by antihypertensive treatment, possibly via an interference with lipoprotein lipase (LPL) activity. The aims of this study were to investigate the metabolic and hemodynamic factors that can interfere with plasma postheparin LPL activity in a sample of 13 patients with mild, uncomplicated arterial hypertension. The effects of vasodilator administration (prazosin and hydralazine) alone or in combination with a β-blocker (propranolol) were also studied. A direct correlation between serum insulin levels and LPL activity was found during placebo treatment. This was confirmed by multiple regression analysis, which also showed a positive correlation of LPL activity with aortic flow velocity and plasma adrenaline (F significance = 0.0007, R2 = .905). Serum insulin was also directly correlated with cholesterol in high-density lipoproteins (HDLs) and in the HDL2 subfraction. A significant decrease in LPL activity was observed during the addition of propranolol to vasodilators as compared with vasodilators alone. A positive correlation was found between LPL and adrenaline changes induced by the combined treatment. These data suggest that LPL may play a role in the pathophysiologic connections between insulin action, the adrenergic nervous system (ANS), and lipid metabolism. © 1995.
Arterial hypertension is frequently associated with serum lipid abnormalities. Lipid metabolism can also be affected by antihypertensive treatment, possibly via an interference with lipoprotein lipase (LPL) activity. The aims of this study were to investigate the metabolic and hemodynamic factors that can interfere with plasma postheparin LPL activity in a sample of 13 patients with mild, uncomplicated arterial hypertension. The effects of vasodilator administration (prazosin and hydralazine) alone or in combination with a β-blocker (propranolol) were also studied. A direct correlation between serum insulin levels and LPL activity was found during placebo treatment. This was confirmed by multiple regression analysis, which also showed a positive correlation of LPL activity with aortic flow velocity and plasma adrenaline (F significance = 0.0007, R2 = .905). Serum insulin was also directly correlated with cholesterol in high-density lipoproteins (HDLs) and in the HDL2 subfraction. A significant decrease in LPL activity was observed during the addition of propranolol to vasodilators as compared with vasodilators alone. A positive correlation was found between LPL and adrenaline changes induced by the combined treatment. These data suggest that LPL may play a role in the pathophysiologic connections between insulin action, the adrenergic nervous system (ANS), and lipid metabolism. © 1995.
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Factors affecting lipoprotein lipase in hypertensive patients
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Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (378 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (443 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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Biondi B, Fazio S, Cuocolo A, Sabatini D, Nicolai E, Lombardi G, Salvatore M, Sacca L
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine (336 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Impact Factor: 4.575
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* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (313 views)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (388 views)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Bucci M, Cigliano L, Vellecco V, D'Andrea LD, Ziaco B, Rossi A, Sautebin L, Carlucci A, Abrescia P, Pedone C, Ianaro A, Cirino G
* Apolipoprotein A-I (ApoA-I) mimetic peptide P2a by restoring cholesterol esterification unmasks ApoA-I anti-inflammatory endogenous activity in vivo (386 views)
J Pharmacol Exp Ther (ISSN: 1521-0103, 0022-3565), 2012 Mar; 340(3): 716-722.
Impact Factor: 3.891
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Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G
* CaMK4 gene deletion induces hypertension (349 views)
J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D.
Impact Factor: 2.882
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Sorriento D, Santulli G, Del Giudice C, Anastasio A, Trimarco B, Iaccarino G
* Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo (423 views)
Hypertensionhypertension (ISSN: 0194-911x), 2012; 60(1): 129-136.
Impact Factor: 6.873
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Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (319 views)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (377 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Manganelli F, Spadafora M, Varrella P, Peluso G, Sauro R, Di Lorenzo E, Rosato G, Daniele S, Cuocolo A
* Addition of atropine to submaximal exercise stress testing in patients evaluated for suspected ischaemia with SPECT imaging: a randomized, placebo-controlled trial (357 views)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 Feb; 38(2): 245-251.
Impact Factor: 4.991
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (410 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Sorriento D, Iaccarino G, Trimarco B
The role of the transcription factor nuclear factor kappa B in the regulation of cardiac hypertrophy (410 views)
High Blood Press Cardiovasc Prev High Blood Pressure And Cardiovascular Prevention (ISSN: 1120-9879), 2010; 17(4): 209-217.
Impact Factor: 0
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Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (449 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
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Cigliano L, D'Andrea LD, Maresca B, Serino M, Carlucci A, Salvatore A, Spagnuolo MS, Scigliuolo G, Pedone C, Abrescia P
* Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin (393 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 2008 Nov; 389(11): 1421-1426.
Impact Factor: 3.035
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Ferro A, Pellegrino T, Spinelli L, Acampa W, Petretta M, Cuocolo A
* Comparison Between Dobutamine Echocardiography and Single-Photon Emission Computed Tomography for Interpretive Reproducibility (319 views)
Am J Cardiol (ISSN: 0002-9149), 2007 Oct 15; 100(8): 1239-1244.
Impact Factor: 3.603
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Maestri R, Pinna G, Accardo A, Allegrini P, Balocchi R, D'ADDIO G, Ferrario M, Menicucci D, Porta A, Sassi R
* Nonlinear indices of heart rate variability in chronic heart failure patients: Redundancy and comparative clinical value (373 views)
J Cardiovasc Electrophysiol (ISSN: 1045-3873), 2007; 18(4): 425-433.
Impact Factor: 3.475
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Palmieri V, Storto G, Arezzi E, Pellegrino T, Mancini M, Di Minno G, Ferrara AL, Cuocolo A, Celentano A
* Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects (311 views)
J Hum Hypertens (ISSN: 0950-9240), 2005 Dec; 19(12): 941-950.
Impact Factor: 2.405
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (486 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R
* 3. 0 T perfusion MR imaging (694 views)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812.
Impact Factor: 0.023
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (581 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (378 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
View Export to BibTeX Export to EndNote
Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (443 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
View Export to BibTeX Export to EndNote
Biondi B, Fazio S, Cuocolo A, Sabatini D, Nicolai E, Lombardi G, Salvatore M, Sacca L
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine (336 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Impact Factor: 4.575
View Export to BibTeX Export to EndNote
22 Records (22 excluding Abstracts).
Total impact factor: 76.565 (76.565 excluding Abstracts).
Total 5 year impact factor: 71.285 (71.285 excluding Abstracts).
Total impact factor: 76.565 (76.565 excluding Abstracts).
Total 5 year impact factor: 71.285 (71.285 excluding Abstracts).
375 views. Last view on Sunday 19 March 2023, 13:52:09
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