Primary systemic amyloidosis with giant hepatomegaly and a swiftly progressive course (437 views)
J Clin Gastroenterol (ISSN: 0192-0790), 1997 Apr; 24(3): 173-175.
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Paper type: Journal Article,
Impact factor: 0.936, 5-year impact factor: 2.61
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0030958389&partnerID=40&md5=dbb52df05e1834fcc9ff67a5981a6314
Keywords: Amyloidosis, Cholestasis, Hepatomegaly, Portal Hypertension, Alkaline Phosphatase, Aminotransferase, Adult, Aminotransferase Blood Level, Article, Ascites, Case Report, Esophagus Varices, Female, Human, Human Tissue, Priority Journal, Biopsy, Intrahepatic, Fatal Outcome, Liver, Liver Function Tests, Middle Aged,
Affiliations:
Nuclear Medicine Department, University Federico II, Naples, Italy
Gastroenterology Unit, University Federico II, Naples, Italy
Corso Vittorio Emanuele, 670, 80122 Napoli, Italy
References:
Not available.
J Clin Gastroenterol (ISSN: 0192-0790), 1997 Apr; 24(3): 173-175.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 0.936, 5-year impact factor: 2.61
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0030958389&partnerID=40&md5=dbb52df05e1834fcc9ff67a5981a6314
Keywords: Amyloidosis, Cholestasis, Hepatomegaly, Portal Hypertension, Alkaline Phosphatase, Aminotransferase, Adult, Aminotransferase Blood Level, Article, Ascites, Case Report, Esophagus Varices, Female, Human, Human Tissue, Priority Journal, Biopsy, Intrahepatic, Fatal Outcome, Liver, Liver Function Tests, Middle Aged,
Affiliations:
Nuclear Medicine Department, University Federico II, Naples, Italy
Gastroenterology Unit, University Federico II, Naples, Italy
Corso Vittorio Emanuele, 670, 80122 Napoli, Italy
References:
Not available.
Primary systemic amyloidosis with giant hepatomegaly and a swiftly progressive course
Although the involvement of the liver is common in systemic amyloidosis (AL), clinical features of hepatic dysfunction and liver chemistry abnormalities are often mild or absent. A mild increase in the serum alkaline phosphatase value is the most common finding. Hypertransaminasemia, hyperbilirubinemia, and portal hypertension with ascites and gastroesophageal varices occur late in the course of the disease and predict a short survival. We describe the case of a 58-year-old woman with AL, whose dramatic and unusual clinical picture, consisting of giant hepatomegaly, hypertransaminasemia, increase in alkaline phosphatase, esophageal varices, and ascites, was rapidly complicated by severe obstructive cholestasis.
Although the involvement of the liver is common in systemic amyloidosis (AL), clinical features of hepatic dysfunction and liver chemistry abnormalities are often mild or absent. A mild increase in the serum alkaline phosphatase value is the most common finding. Hypertransaminasemia, hyperbilirubinemia, and portal hypertension with ascites and gastroesophageal varices occur late in the course of the disease and predict a short survival. We describe the case of a 58-year-old woman with AL, whose dramatic and unusual clinical picture, consisting of giant hepatomegaly, hypertransaminasemia, increase in alkaline phosphatase, esophageal varices, and ascites, was rapidly complicated by severe obstructive cholestasis.
Primary systemic amyloidosis with giant hepatomegaly and a swiftly progressive course
| ▼ Biochemical and functional characterization of intrinsically disordered proteins (IDPs) in human diseases |
Primary systemic amyloidosis with giant hepatomegaly and a swiftly progressive course
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* Imaging features of small bowel amyloidosis at PET/CT (448 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2012 Oct; 37(5): 911-911.
Impact Factor: 1.905
View Export to BibTeX Export to EndNote
Pier PM
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Impact Factor: 1.555
View Export to BibTeX Export to EndNote
Mainenti PP, Segreto S, Mancini M, Rispo A, Cozzolino I, Masone S, Rinaldi CR, Nardone G, Salvatore M
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Impact Factor: 2.24
View Export to BibTeX Export to EndNote
Sciacca MFM, Pappalardo M, Attanasio F, Milardi D, La Rosa C, Grasso DM
* Are fibril growth and membrane damage linked processes? An experimental and computational study of IAPP(12-18) and IAPP(21-27) peptides (701 views)
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Impact Factor: 2.631
View Export to BibTeX Export to EndNote
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Epilepsia (ISSN: 1528-1167, 0013-9580), 2009 Sep; 50(9): 2140-2146.
Impact Factor: 4.052
View Export to BibTeX Export to EndNote
Palladino P, Ronga L, Benedetti E, Rossi F, Ragone R
* Peptide Fragment Approach to Prion Misfolding: The Alpha-2 Domain (843 views)
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2009 Sep; 15(3): 165-176.
Impact Factor: 0.869
View Export to BibTeX Export to EndNote
D'Auria G, Vacatello M, Falcigno L, Paduano L, Mangiapia G, Calvanese L, Gambaretto R, Dettin M, Paolillo L
* Self-assembling properties of ionic-complementary peptides (973 views)
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Impact Factor: 1.807
View Export to BibTeX Export to EndNote
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Impact Factor: 2.207
View Export to BibTeX Export to EndNote
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Impact Factor: 2.345
View Export to BibTeX Export to EndNote
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Impact Factor: 2.433
View Export to BibTeX Export to EndNote
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Impact Factor: 2.855
View Export to BibTeX Export to EndNote
De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (718 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
View Export to BibTeX Export to EndNote
Mainenti PP, Camera L, Nicotra S, Cantalupo T, Soscia E, Vizio DD, Insabato G, Salvatore M
* Splenic hypoperfusion as a sign of systemic amyloidosis (675 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2005 Dec; 30(6): 768-772.
Impact Factor: 1.034
View Export to BibTeX Export to EndNote
Mainenti PP, Cantalupo T, Nicotra S, Camera L, Imbriaco M, Di Vizio D, Insabato L, Salvatore M
* Systemic amyloidosis: The CT sign of splenic hypoperfusion (659 views)
Amyloid (ISSN: 1350-6129), 2004 Dec; 11(4): 281-282.
Impact Factor: 1.886
View Export to BibTeX Export to EndNote
Romano M, Giojelli A, Capuano G, Pomponi D, Salvatore M
* Partial splenic embolization in patients with idiopathic portal hypertension (1115 views)
Eur J Radiol (ISSN: 0720-048x), 2004 Mar; 49(3): 268-273.
Impact Factor: 1.745
View Export to BibTeX Export to EndNote
Mainenti PP, D'Agostino L, Soscia E, Romano M, Salvatore M
* Hepatic and splenic amyloidosis: Dual-phase spiral CT findings (715 views)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Sep; 28(5): 688-690.
Impact Factor: 0.996
View Export to BibTeX Export to EndNote
Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E, Willbold D
* Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide Aβ1-42 by mirror image phage display (1116 views)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003; 4(8): 748-753.
Impact Factor: 3.992
View Export to BibTeX Export to EndNote
Camera L, Selva G, Puzziello A, Sparano L, Ignarra R, Quarantelli M
* [Castleman's disease: CT and MR findings in a case localized in the portocaval space] (503 views)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2001 Sep; 102(3): 186-188.
Impact Factor: 1.368
View Export to BibTeX Export to EndNote
Oliva A, Marrone G, Della Ragione F, Riccio V, Palumbo R, Rossano F, Zappia V
Isolation and characterization of human embryonic osteoblasts (743 views)
Calcif Tissue Int (ISSN: 0171-967xprint, 0171-967xlinking), 1992 Nov; 51(5): 356-362.
Impact Factor: 2.364
View Export to BibTeX Export to EndNote
27 Records (25 excluding Abstracts).
Total impact factor: 73.825 (67.422 excluding Abstracts).
Total 5 year impact factor: 72.616 (65.88 excluding Abstracts).
Total impact factor: 73.825 (67.422 excluding Abstracts).
Total 5 year impact factor: 72.616 (65.88 excluding Abstracts).
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