Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (597 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Randomized Controlled Trial, Research Support,
Impact factor: 3.438, 5-year impact factor: 3.502
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77349117528&partnerID=40&md5=e1feb30bc96fe1a7a385d80436aa3d76
Keywords: Cereal Fibre, Glucose Metabolism, Insulin Metabolism, Lipid Metabolism, Wholemeal Cereals, C Peptide, Cholesterol, Gastric Inhibitory Polypeptide, Ghrelin, Leptin, Low Density Lipoprotein Cholesterol, Article, Blood, Blood Pressure, Body Weight, Cardiovascular Disease, Clinical Trial, Controlled Clinical Trial, Controlled Study, Crossover Procedure, Diet Restriction, Female, Food Handling, Glucose Blood Level, Human, Insulin Resistance, Middle Aged, Randomized Controlled Trial, Risk Factor, Wheat, Blood Glucose, C-Peptide, Cross-Over Studies, Fasting, Triticum, Triticum Aestivum, Analysis, Cardiovascular Diseases Prevention,
Affiliations:
*** IBB - CNR ***
Institute of Food Science, National Research Council (CNR), Via Roma 52 A/C, 83100 Avellino, Italy
Institute of Biostructures and Bioimaging, CNR, Naples, Italy
Department of Clinical and Experimental Medicine, School of Medicine, Federico II University, Naples, Italy
Department of Food Science, Federico II University, Naples, Italy
R and D, Barilla G and R F.lli. SpA, Parma, Italy
Department of Public Health, University of Parma, Parma, Italy
References:
Liu, S., Manson, J.E., Stampfer, M.J., Hu, F.B., Giovannucci, E., Colditz, G.A., A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US women (2000) Am J Public Health, 90, pp. 1409-141
Fung, T.T., Hu, F.B., Pereira, M.A., Liu, S., Stampfer, M.J., Colditz, G.A., Whole-grain intake and the risk of type 2 diabetes: a prospective study in men (2002) Am J Clin Nutr, 76, pp. 535-540
Sahyoun, N.R., Jacques, P.F., Zhang, X.L., Juan, W., McKeown, N.M., Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults (2006) Am J Clin Nutr, 83, pp. 124-131
Steffen, L.M., Jacobs Jr., D.R., Stevens, J., Shahar, E., Carithers, T., Folsom, A.R., Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study (2003) Am J Clin Nutr, 78, pp. 383-390
Slavin, J.L., Martini, M.C., Jacobs Jr., D.R., Marquart, L., Plausible mechanisms for the protectiveness of whole grains (1999) Am J Clin Nutr, 70 (3 SUPPL), pp. 459S-463S
Schulze, M.B., Schulz, M., Heidemann, C., Schienkiewitz, A., Hoffmann, K., Boeing, H., Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis (2007) Arch Intern Med, 167, pp. 956-965
Kaline, K., Bornstein, S.R., Bergmann, A., Hauner, H., Schwarz, P.E., The importance and effect of dietary fiber in diabetes prevention with particular consideration of whole grain products (2007) Horm Metab Res, 39, pp. 687-693
Khaw, K.T., Barrett-Connor, E., Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study (1987) Am J Epidemiol, 126, pp. 1093-1102
Rimm, E.B., Ascherio, A., Giovannucci, E., Spiegelman, D., Stampfer, M.J., Willett, W.C., Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men (1996) JAMA, 275, pp. 447-451
Jacobs Jr., D.R., Meyer, K.A., Kushi, L.H., Folsom, A.R., Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: the Iowa Women's Health Study (1998) Am J Clin Nutr, 68, pp. 248-257
Jensen, M.K., Koh-Banerjee, P., Hu, F.B., Franz, M., Sampson, L., Grønbaek, M., Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men (2004) Am J Clin Nutr, 80, pp. 1492-1499
Montonen, J., Knekt, P., Järvinen, R., Aromaa, A., Reunanen, A., Whole-grain and fiber intake and the incidence of type 2 diabetes (2003) Am J Clin Nutr, 77, pp. 622-629
McKeown, N.M., Meigs, J.B., Liu, S., Wilson, P.W., Jacques, P.F., Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study (2002) Am J Clin Nutr, 76, pp. 390-398
Jang, Y., Lee, J.H., Kim, O.Y., Park, H.Y., Lee, S.Y., Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease: randomized controlled clinical trial (2001) Arterioscler Thromb Vasc Biol, 21, pp. 2065-2071
Pereira, M.A., Jacobs Jr., D.R., Pins, J.J., Raatz, S.K., Gross, M.D., Slavin, J.L., Effect of whole grains on insulin sensitivity in overweight hyperinsulinemic adults (2002) Am J Clin Nutr, 75, pp. 848-855
Liese, A.D., Roach, A.K., Sparks, K.C., Marquart, L., D'Agostino Jr., R.B., Mayer-Davis, E.J., Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study (2003) Am J Clin Nutr, 78, pp. 965-971
Qi, L., van Dam, R.M., Liu, S., Franz, M., Mantzoros, C., Hu, F.B., Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women (2006) Diabetes Care, 29, pp. 207-211
Carlson, K., Lipoprotein fractionation (1973) J Clin Pathol Suppl (Assoc Clin Pathol), 5, pp. 32-37
Seigler, L., Wu, W.T., Separation of serum high density lipoprotein for cholesterol determination: ultracentrifugation vs. precipitation with sodium phosphotungstate and magnesium chloride (1981) Clin Chem, 27, pp. 838-841
Benzie, I.F., Strain, J.J., The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay (1996) Anal Biochem, 239, pp. 70-76
Gimeno, E., Castellote, A.I., Lamuela-Raventós, R.M., de la Torre-Boronat, M.C., López-Sabater, M.C., Rapid high-performance liquid chromatographic method for the simultaneous determination of retinol, alpha-tocopherol and beta-carotene in human plasma and low-density lipoproteins (2001) J Chromatogr B Biomed Sci Appl, 758, pp. 315-322
Munoz, J.M., Sandstead, H.H., Jacob, R.A., Logan Jr., G.M., Reck, S.J., Klevay, L.M., Effects of some cereal brans and textured vegetable protein on plasma lipids (1979) Am J Clin Nutr, 32, pp. 580-592
Groen, J.J., Why bread in the diet lowers serum cholesterol (1973) Proc Nutr Soc, 32, pp. 159-167
Jenkins, D.J., Hill, M.S., Cummings, J.H., Effect of wheat fiber on blood lipids, fecal steroid excretion and serum iron (1975) Am J Clin Nutr, 28, pp. 1408-1411
Eastwood, M.A., Kirkpatrick, J.R., Mitchell, W.D., Bone, A., Hamilton, T., Effects of dietary supplements of wheat bran and cellulose on faeces and bowel function (1973) Br Med J, 4, pp. 392-394
Jenkins, D.J., Kendall, C.W., Augustin, L.S., Martini, M.C., Axelsen, M., Faulkner, D., Effect of wheat bran on glycemic control and risk factors for cardiovascular disease in type 2 diabetes (2002) Diabetes Care, 25, pp. 1522-1528
Blackburn, P., Côté, M., Lamarche, B., Couillard, C., Pascot, A., Tremblay, A., Impact of postprandial variation in triglyceridemia on low-density lipoprotein particle size (2003) Metabolism, 52, pp. 1379-1386
Weickert, M.O., Möhlig, M., Schöfl, C., Arafat, A.M., Otto, B., Viehoff, H., Cereal fiber improves whole-body insulin sensitivity in overweight and obese women (2006) Diabetes Care, 29, pp. 775-780
Andersson, A., Tengblad, S., Karlström, B., Kamal-Eldin, A., Landberg, R., Basu, S., Whole-grain foods do not affect insulin sensitivity or markers of lipid peroxidation and inflammation in healthy, moderately overweight subjects (2007) J Nutr, 137, pp. 1401-1407
Takaya, J., Higashino, H., Kobayashi, Y., Intracellular magnesium and insulin resistance (2004) Magnes Res, 17, pp. 126-136
Katcher, H.I., Legro, R.S., Kunselman, A.R., Gillies, P.J., Demers, L.M., Bagshaw, D.M., The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome (2008) Am J Clin Nutr, 87, pp. 79-90
Kern, S.M., Bennett, R.N., Mellon, F.A., Kroon, P.A., Garcia-Conesa, M.T., Absorption of hydroxycinnamates in humans after high-bran cereal consumption (2003) J Agric Food Chem, 51, pp. 6050-6055
Adam, A., Crespy, V., Levrat-Verny, M.A., Leenhardt, F., Leuillet, M., Demigne, C., The bioavailability of ferulic acid is governed primarily by the food matrix rather than its metabolism in intestine and liver in rats (2002) J Nutr, 132, pp. 1962-1968
Liu, S., Willett, W.C., Manson, J.E., Hu, F.B., Rosner, B., Colditz, G., Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women (2003) Am J Clin Nutr, 78, pp. 920-927
Fung, T. T., Hu, F. B., Pereira, M. A., Liu, S., Stampfer, M. J., Colditz, G. A., Whole-grain intake and the risk of type 2 diabetes: a prospective study in men (2002) Am J Clin Nutr, 76, pp. 535-540
Sahyoun, N. R., Jacques, P. F., Zhang, X. L., Juan, W., McKeown, N. M., Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults (2006) Am J Clin Nutr, 83, pp. 124-131
Steffen, L. M., Jacobs Jr., D. R., Stevens, J., Shahar, E., Carithers, T., Folsom, A. R., Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study (2003) Am J Clin Nutr, 78, pp. 383-390
Slavin, J. L., Martini, M. C., Jacobs Jr., D. R., Marquart, L., Plausible mechanisms for the protectiveness of whole grains (1999) Am J Clin Nutr, 70 (3 SUPPL), pp. 459S-463S
Schulze, M. B., Schulz, M., Heidemann, C., Schienkiewitz, A., Hoffmann, K., Boeing, H., Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis (2007) Arch Intern Med, 167, pp. 956-965
Khaw, K. T., Barrett-Connor, E., Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study (1987) Am J Epidemiol, 126, pp. 1093-1102
Rimm, E. B., Ascherio, A., Giovannucci, E., Spiegelman, D., Stampfer, M. J., Willett, W. C., Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men (1996) JAMA, 275, pp. 447-451
Jensen, M. K., Koh-Banerjee, P., Hu, F. B., Franz, M., Sampson, L., Gr nbaek, M., Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men (2004) Am J Clin Nutr, 80, pp. 1492-1499
McKeown, N. M., Meigs, J. B., Liu, S., Wilson, P. W., Jacques, P. F., Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study (2002) Am J Clin Nutr, 76, pp. 390-398
Jang, Y., Lee, J. H., Kim, O. Y., Park, H. Y., Lee, S. Y., Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease: randomized controlled clinical trial (2001) Arterioscler Thromb Vasc Biol, 21, pp. 2065-2071
Pereira, M. A., Jacobs Jr., D. R., Pins, J. J., Raatz, S. K., Gross, M. D., Slavin, J. L., Effect of whole grains on insulin sensitivity in overweight hyperinsulinemic adults (2002) Am J Clin Nutr, 75, pp. 848-855
Liese, A. D., Roach, A. K., Sparks, K. C., Marquart, L., D'Agostino Jr., R. B., Mayer-Davis, E. J., Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study (2003) Am J Clin Nutr, 78, pp. 965-971
Benzie, I. F., Strain, J. J., The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay (1996) Anal Biochem, 239, pp. 70-76
Munoz, J. M., Sandstead, H. H., Jacob, R. A., Logan Jr., G. M., Reck, S. J., Klevay, L. M., Effects of some cereal brans and textured vegetable protein on plasma lipids (1979) Am J Clin Nutr, 32, pp. 580-592
Groen, J. J., Why bread in the diet lowers serum cholesterol (1973) Proc Nutr Soc, 32, pp. 159-167
Jenkins, D. J., Hill, M. S., Cummings, J. H., Effect of wheat fiber on blood lipids, fecal steroid excretion and serum iron (1975) Am J Clin Nutr, 28, pp. 1408-1411
Eastwood, M. A., Kirkpatrick, J. R., Mitchell, W. D., Bone, A., Hamilton, T., Effects of dietary supplements of wheat bran and cellulose on faeces and bowel function (1973) Br Med J, 4, pp. 392-394
Jenkins, D. J., Kendall, C. W., Augustin, L. S., Martini, M. C., Axelsen, M., Faulkner, D., Effect of wheat bran on glycemic control and risk factors for cardiovascular disease in type 2 diabetes (2002) Diabetes Care, 25, pp. 1522-1528
Blackburn, P., C t, M., Lamarche, B., Couillard, C., Pascot, A., Tremblay, A., Impact of postprandial variation in triglyceridemia on low-density lipoprotein particle size (2003) Metabolism, 52, pp. 1379-1386
Weickert, M. O., M hlig, M., Sch fl, C., Arafat, A. M., Otto, B., Viehoff, H., Cereal fiber improves whole-body insulin sensitivity in overweight and obese women (2006) Diabetes Care, 29, pp. 775-780
Katcher, H. I., Legro, R. S., Kunselman, A. R., Gillies, P. J., Demers, L. M., Bagshaw, D. M., The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome (2008) Am J Clin Nutr, 87, pp. 79-90
Kern, S. M., Bennett, R. N., Mellon, F. A., Kroon, P. A., Garcia-Conesa, M. T., Absorption of hydroxycinnamates in humans after high-bran cereal consumption (2003) J Agric Food Chem, 51, pp. 6050-6055
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Randomized Controlled Trial, Research Support,
Impact factor: 3.438, 5-year impact factor: 3.502
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77349117528&partnerID=40&md5=e1feb30bc96fe1a7a385d80436aa3d76
Keywords: Cereal Fibre, Glucose Metabolism, Insulin Metabolism, Lipid Metabolism, Wholemeal Cereals, C Peptide, Cholesterol, Gastric Inhibitory Polypeptide, Ghrelin, Leptin, Low Density Lipoprotein Cholesterol, Article, Blood, Blood Pressure, Body Weight, Cardiovascular Disease, Clinical Trial, Controlled Clinical Trial, Controlled Study, Crossover Procedure, Diet Restriction, Female, Food Handling, Glucose Blood Level, Human, Insulin Resistance, Middle Aged, Randomized Controlled Trial, Risk Factor, Wheat, Blood Glucose, C-Peptide, Cross-Over Studies, Fasting, Triticum, Triticum Aestivum, Analysis, Cardiovascular Diseases Prevention,
Affiliations:
*** IBB - CNR ***
Institute of Food Science, National Research Council (CNR), Via Roma 52 A/C, 83100 Avellino, Italy
Institute of Biostructures and Bioimaging, CNR, Naples, Italy
Department of Clinical and Experimental Medicine, School of Medicine, Federico II University, Naples, Italy
Department of Food Science, Federico II University, Naples, Italy
R and D, Barilla G and R F.lli. SpA, Parma, Italy
Department of Public Health, University of Parma, Parma, Italy
References:
Liu, S., Manson, J.E., Stampfer, M.J., Hu, F.B., Giovannucci, E., Colditz, G.A., A prospective study of whole-grain intake and risk of type 2 diabetes mellitus in US women (2000) Am J Public Health, 90, pp. 1409-141
Fung, T.T., Hu, F.B., Pereira, M.A., Liu, S., Stampfer, M.J., Colditz, G.A., Whole-grain intake and the risk of type 2 diabetes: a prospective study in men (2002) Am J Clin Nutr, 76, pp. 535-540
Sahyoun, N.R., Jacques, P.F., Zhang, X.L., Juan, W., McKeown, N.M., Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults (2006) Am J Clin Nutr, 83, pp. 124-131
Steffen, L.M., Jacobs Jr., D.R., Stevens, J., Shahar, E., Carithers, T., Folsom, A.R., Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study (2003) Am J Clin Nutr, 78, pp. 383-390
Slavin, J.L., Martini, M.C., Jacobs Jr., D.R., Marquart, L., Plausible mechanisms for the protectiveness of whole grains (1999) Am J Clin Nutr, 70 (3 SUPPL), pp. 459S-463S
Schulze, M.B., Schulz, M., Heidemann, C., Schienkiewitz, A., Hoffmann, K., Boeing, H., Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis (2007) Arch Intern Med, 167, pp. 956-965
Kaline, K., Bornstein, S.R., Bergmann, A., Hauner, H., Schwarz, P.E., The importance and effect of dietary fiber in diabetes prevention with particular consideration of whole grain products (2007) Horm Metab Res, 39, pp. 687-693
Khaw, K.T., Barrett-Connor, E., Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study (1987) Am J Epidemiol, 126, pp. 1093-1102
Rimm, E.B., Ascherio, A., Giovannucci, E., Spiegelman, D., Stampfer, M.J., Willett, W.C., Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men (1996) JAMA, 275, pp. 447-451
Jacobs Jr., D.R., Meyer, K.A., Kushi, L.H., Folsom, A.R., Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: the Iowa Women's Health Study (1998) Am J Clin Nutr, 68, pp. 248-257
Jensen, M.K., Koh-Banerjee, P., Hu, F.B., Franz, M., Sampson, L., Grønbaek, M., Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men (2004) Am J Clin Nutr, 80, pp. 1492-1499
Montonen, J., Knekt, P., Järvinen, R., Aromaa, A., Reunanen, A., Whole-grain and fiber intake and the incidence of type 2 diabetes (2003) Am J Clin Nutr, 77, pp. 622-629
McKeown, N.M., Meigs, J.B., Liu, S., Wilson, P.W., Jacques, P.F., Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study (2002) Am J Clin Nutr, 76, pp. 390-398
Jang, Y., Lee, J.H., Kim, O.Y., Park, H.Y., Lee, S.Y., Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease: randomized controlled clinical trial (2001) Arterioscler Thromb Vasc Biol, 21, pp. 2065-2071
Pereira, M.A., Jacobs Jr., D.R., Pins, J.J., Raatz, S.K., Gross, M.D., Slavin, J.L., Effect of whole grains on insulin sensitivity in overweight hyperinsulinemic adults (2002) Am J Clin Nutr, 75, pp. 848-855
Liese, A.D., Roach, A.K., Sparks, K.C., Marquart, L., D'Agostino Jr., R.B., Mayer-Davis, E.J., Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study (2003) Am J Clin Nutr, 78, pp. 965-971
Qi, L., van Dam, R.M., Liu, S., Franz, M., Mantzoros, C., Hu, F.B., Whole-grain, bran, and cereal fiber intakes and markers of systemic inflammation in diabetic women (2006) Diabetes Care, 29, pp. 207-211
Carlson, K., Lipoprotein fractionation (1973) J Clin Pathol Suppl (Assoc Clin Pathol), 5, pp. 32-37
Seigler, L., Wu, W.T., Separation of serum high density lipoprotein for cholesterol determination: ultracentrifugation vs. precipitation with sodium phosphotungstate and magnesium chloride (1981) Clin Chem, 27, pp. 838-841
Benzie, I.F., Strain, J.J., The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay (1996) Anal Biochem, 239, pp. 70-76
Gimeno, E., Castellote, A.I., Lamuela-Raventós, R.M., de la Torre-Boronat, M.C., López-Sabater, M.C., Rapid high-performance liquid chromatographic method for the simultaneous determination of retinol, alpha-tocopherol and beta-carotene in human plasma and low-density lipoproteins (2001) J Chromatogr B Biomed Sci Appl, 758, pp. 315-322
Munoz, J.M., Sandstead, H.H., Jacob, R.A., Logan Jr., G.M., Reck, S.J., Klevay, L.M., Effects of some cereal brans and textured vegetable protein on plasma lipids (1979) Am J Clin Nutr, 32, pp. 580-592
Groen, J.J., Why bread in the diet lowers serum cholesterol (1973) Proc Nutr Soc, 32, pp. 159-167
Jenkins, D.J., Hill, M.S., Cummings, J.H., Effect of wheat fiber on blood lipids, fecal steroid excretion and serum iron (1975) Am J Clin Nutr, 28, pp. 1408-1411
Eastwood, M.A., Kirkpatrick, J.R., Mitchell, W.D., Bone, A., Hamilton, T., Effects of dietary supplements of wheat bran and cellulose on faeces and bowel function (1973) Br Med J, 4, pp. 392-394
Jenkins, D.J., Kendall, C.W., Augustin, L.S., Martini, M.C., Axelsen, M., Faulkner, D., Effect of wheat bran on glycemic control and risk factors for cardiovascular disease in type 2 diabetes (2002) Diabetes Care, 25, pp. 1522-1528
Blackburn, P., Côté, M., Lamarche, B., Couillard, C., Pascot, A., Tremblay, A., Impact of postprandial variation in triglyceridemia on low-density lipoprotein particle size (2003) Metabolism, 52, pp. 1379-1386
Weickert, M.O., Möhlig, M., Schöfl, C., Arafat, A.M., Otto, B., Viehoff, H., Cereal fiber improves whole-body insulin sensitivity in overweight and obese women (2006) Diabetes Care, 29, pp. 775-780
Andersson, A., Tengblad, S., Karlström, B., Kamal-Eldin, A., Landberg, R., Basu, S., Whole-grain foods do not affect insulin sensitivity or markers of lipid peroxidation and inflammation in healthy, moderately overweight subjects (2007) J Nutr, 137, pp. 1401-1407
Takaya, J., Higashino, H., Kobayashi, Y., Intracellular magnesium and insulin resistance (2004) Magnes Res, 17, pp. 126-136
Katcher, H.I., Legro, R.S., Kunselman, A.R., Gillies, P.J., Demers, L.M., Bagshaw, D.M., The effects of a whole grain-enriched hypocaloric diet on cardiovascular disease risk factors in men and women with metabolic syndrome (2008) Am J Clin Nutr, 87, pp. 79-90
Kern, S.M., Bennett, R.N., Mellon, F.A., Kroon, P.A., Garcia-Conesa, M.T., Absorption of hydroxycinnamates in humans after high-bran cereal consumption (2003) J Agric Food Chem, 51, pp. 6050-6055
Adam, A., Crespy, V., Levrat-Verny, M.A., Leenhardt, F., Leuillet, M., Demigne, C., The bioavailability of ferulic acid is governed primarily by the food matrix rather than its metabolism in intestine and liver in rats (2002) J Nutr, 132, pp. 1962-1968
Liu, S., Willett, W.C., Manson, J.E., Hu, F.B., Rosner, B., Colditz, G., Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women (2003) Am J Clin Nutr, 78, pp. 920-927
Fung, T. T., Hu, F. B., Pereira, M. A., Liu, S., Stampfer, M. J., Colditz, G. A., Whole-grain intake and the risk of type 2 diabetes: a prospective study in men (2002) Am J Clin Nutr, 76, pp. 535-540
Sahyoun, N. R., Jacques, P. F., Zhang, X. L., Juan, W., McKeown, N. M., Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults (2006) Am J Clin Nutr, 83, pp. 124-131
Steffen, L. M., Jacobs Jr., D. R., Stevens, J., Shahar, E., Carithers, T., Folsom, A. R., Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study (2003) Am J Clin Nutr, 78, pp. 383-390
Slavin, J. L., Martini, M. C., Jacobs Jr., D. R., Marquart, L., Plausible mechanisms for the protectiveness of whole grains (1999) Am J Clin Nutr, 70 (3 SUPPL), pp. 459S-463S
Schulze, M. B., Schulz, M., Heidemann, C., Schienkiewitz, A., Hoffmann, K., Boeing, H., Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis (2007) Arch Intern Med, 167, pp. 956-965
Khaw, K. T., Barrett-Connor, E., Dietary fiber and reduced ischemic heart disease mortality rates in men and women: a 12-year prospective study (1987) Am J Epidemiol, 126, pp. 1093-1102
Rimm, E. B., Ascherio, A., Giovannucci, E., Spiegelman, D., Stampfer, M. J., Willett, W. C., Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease among men (1996) JAMA, 275, pp. 447-451
Jensen, M. K., Koh-Banerjee, P., Hu, F. B., Franz, M., Sampson, L., Gr nbaek, M., Intakes of whole grains, bran, and germ and the risk of coronary heart disease in men (2004) Am J Clin Nutr, 80, pp. 1492-1499
McKeown, N. M., Meigs, J. B., Liu, S., Wilson, P. W., Jacques, P. F., Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study (2002) Am J Clin Nutr, 76, pp. 390-398
Jang, Y., Lee, J. H., Kim, O. Y., Park, H. Y., Lee, S. Y., Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease: randomized controlled clinical trial (2001) Arterioscler Thromb Vasc Biol, 21, pp. 2065-2071
Pereira, M. A., Jacobs Jr., D. R., Pins, J. J., Raatz, S. K., Gross, M. D., Slavin, J. L., Effect of whole grains on insulin sensitivity in overweight hyperinsulinemic adults (2002) Am J Clin Nutr, 75, pp. 848-855
Liese, A. D., Roach, A. K., Sparks, K. C., Marquart, L., D'Agostino Jr., R. B., Mayer-Davis, E. J., Whole-grain intake and insulin sensitivity: the Insulin Resistance Atherosclerosis Study (2003) Am J Clin Nutr, 78, pp. 965-971
Benzie, I. F., Strain, J. J., The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay (1996) Anal Biochem, 239, pp. 70-76
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Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people
Background and aim: The intake of wholemeal foods is consistently associated with reduced risk of type 2 diabetes and cardiovascular diseases in epidemiological studies, although the mechanisms of this association are unclear. Here we aim to compare in healthy subjects the metabolic effects of a diet rich in wholemeal wheat foods versus one based on the same products in refined form. Methods and results: Fifteen healthy individuals (12 M/3 F), mean age 54.5 ± 7.6 years, BMI 27.4 ± 3.0 kg/m2 (mean ± SD), participated in a randomized sequential crossover study. After 2 weeks run-in, participants were randomly assigned to two isoenergetic diets with similar macronutrient composition, one rich in wholemeal wheat foods and the other with the same foods but in refined form (cereal fibre 23.1 vs. 9.8 g/day). After the two treatment periods (each lasting 3 weeks) plasma glucose and lipid metabolism, antioxidant activity, acetic acid, magnesium, adipokines, incretins and high-sensitivity C-reactive protein (hs-CRP) were measured at fasting and for 4 h after a standard test meal (kcal 1103, protein 12%, CHO 53%, fat 35%) based on wholemeal or refined wheat foods, respectively. After the two diets there were no differences in fasting nor in postprandial plasma parameter responses; only glucose was slightly but significantly lower at 240 min after the refined wheat food meal compared to the wholemeal wheat food meal. Conversely, after the wholemeal diet both total (-4.3%; p < 0.03) and LDL (-4.9%; p < 0.04) cholesterol levels were lower than after the refined wheat diet at fasting. Conclusions: Consumption of wholemeal wheat foods for 3 weeks reduces significantly fasting plasma cholesterol as well as LDL cholesterol levels in healthy individuals without major effects on glucose and insulin metabolism, antioxidant status and sub-clinical inflammation markers. © 2009 Elsevier B.V. All rights reserved.
Background and aim: The intake of wholemeal foods is consistently associated with reduced risk of type 2 diabetes and cardiovascular diseases in epidemiological studies, although the mechanisms of this association are unclear. Here we aim to compare in healthy subjects the metabolic effects of a diet rich in wholemeal wheat foods versus one based on the same products in refined form. Methods and results: Fifteen healthy individuals (12 M/3 F), mean age 54.5 ± 7.6 years, BMI 27.4 ± 3.0 kg/m2 (mean ± SD), participated in a randomized sequential crossover study. After 2 weeks run-in, participants were randomly assigned to two isoenergetic diets with similar macronutrient composition, one rich in wholemeal wheat foods and the other with the same foods but in refined form (cereal fibre 23.1 vs. 9.8 g/day). After the two treatment periods (each lasting 3 weeks) plasma glucose and lipid metabolism, antioxidant activity, acetic acid, magnesium, adipokines, incretins and high-sensitivity C-reactive protein (hs-CRP) were measured at fasting and for 4 h after a standard test meal (kcal 1103, protein 12%, CHO 53%, fat 35%) based on wholemeal or refined wheat foods, respectively. After the two diets there were no differences in fasting nor in postprandial plasma parameter responses; only glucose was slightly but significantly lower at 240 min after the refined wheat food meal compared to the wholemeal wheat food meal. Conversely, after the wholemeal diet both total (-4.3%; p < 0.03) and LDL (-4.9%; p < 0.04) cholesterol levels were lower than after the refined wheat diet at fasting. Conclusions: Consumption of wholemeal wheat foods for 3 weeks reduces significantly fasting plasma cholesterol as well as LDL cholesterol levels in healthy individuals without major effects on glucose and insulin metabolism, antioxidant status and sub-clinical inflammation markers. © 2009 Elsevier B.V. All rights reserved.
Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people
| ▼ High-resolution positron emission tomography of the ischaemic mouse heart |
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Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people
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Guzzardi MA, La Rosa F, Campani D, Cacciato Insilla A, De Sena V, Panetta D, Brunetto MR, Bonino F, Collado MC, Iozzo P
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Greco A, Fiumara G, Gargiulo S, Gramanzini M, Brunetti A, Cuocolo A
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Galdiero S, Vitiello M, Finamore E, Mansi R, Galdiero M, Morelli G, Tesauro D
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Santulli G, Lombardi A, Sorriento D, Anastasio A, Del Giudice C, Formisano P, Béguinot F, Trimarco B, Miele C, Iaccarino G
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* Maturation of the Visceral (Gut-Adipose-Liver) Network in Response to the Weaning Reaction versus Adult Age and Impact of Maternal High-Fat Diet (5 views)
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Capozza M, Anemone A, Dhakan C, Della Peruta M, Bracesco M, Zullino S, Villano D, Terreno E, Longo DL, Aime S
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Vitale M, Giacco R, Laiola M, Della Pepa G, Luongo D, Mangione A, Salamone D, Vitaglione P, Ercolini D, Rivellese AA
* Acute and chronic improvement in postprandial glucose metabolism by a diet resembling the traditional Mediterranean dietary pattern: Can SCFAs play a role? (41 views)
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Impact Factor: 6.36
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Costabile G, Vitale M, Luongo D, Naviglio D, Vetrani C, Ciciola P, Tura A, Castello F, Mena P, Del Rio D, Capaldo B, Rivellese AA, Riccardi G, Giacco R
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Clin Nutr (ISSN: 0261-5614linking), 2019 Dec; 38(6): 2727-2734.
Impact Factor: 0.5
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Marchitelli R, Aiello M, Cachia A, Quarantelli M, Cavaliere C, Postiglione A, Tedeschi G, Montella P, Milan G, Salvatore M, Salvatore E, Baron JC, Pappata S
* Simultaneous resting-state FDG-PET/fMRI in Alzheimer Disease: Relationship between glucose metabolism and intrinsic activity (595 views)
Neuroimage (ISSN: 1053-8119linking), 2018 Aug 1; 176: 246-258.
Impact Factor: 5.835
View Export to BibTeX Export to EndNote
Taskinen MR, Soderlund S, Bogl LH, Hakkarainen A, Matikainen N, Pietilainen KH, Rasanen S, Lundbom N, Bjornson E, Eliasson B, Mancina RM, Romeo S, Almeras N, Della Pepa G, Vetrani C, Prinster A, Annuzzi G, Rivellese A, Despres JP, Boren J
* Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity (296 views)
J Intern Med (ISSN: 0954-6820), 2017 May 26; N/D: N/D-N/D.
Impact Factor: 6.754
View Export to BibTeX Export to EndNote
De Rosa V, Iommelli F, Monti M, Fonti R, Votta G, Stoppelli MP, Del Vecchio S
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Impact Factor: 8.738
View Export to BibTeX Export to EndNote
Aiello M, Salvatore E, Cachia A, Pappata S, Cavaliere C, Prinster A, Nicolai E, Salvatore M, Baron JC, Quarantelli M
* Relationship between simultaneously acquired resting-state regional cerebral glucose metabolism and functional MRI: a PET/MR hybrid scanner study (312 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2015 Jun; 113: 111-121.
Impact Factor: 5.463
View Export to BibTeX Export to EndNote
Marcucci G, Cianferotti L, Beck-Peccoz P, Capezzone M, Cetani F, Colao A, Davì MV, Degli Uberti E, Del Prato S, Elisei R, Faggiano A, Ferone D, Foresta C, Fugazzola L, Ghigo E, Giacchetti G, Giorgino F, Lenzi A, Malandrino P, Mannelli M, Marcocci C, Masi L, Pacini F, Opocher G, Radicioni A, Tonacchera M, Vigneri R, Zatelli MC, Brandi ML
* Rare diseases in clinical endocrinology: A taxonomic classification system (617 views)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2015; 38(2): 193-259.
Impact Factor: 1.994
View Export to BibTeX Export to EndNote
Gargiulo S, Petretta MP, Greco A, Panico M, Larobina M, Gramanzini M, Schiattarella GG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Genetic deletion in uncoupling protein 3 augments 18F-fluorodeoxyglucose cardiac uptake in the ischemic heart (416 views)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2014 Sep 8; 14(1): 98-98.
Impact Factor: 1.878
View Export to BibTeX Export to EndNote
Greco A, Fiumara G, Gargiulo S, Gramanzini M, Brunetti A, Cuocolo A
* High-resolution positron emission tomography/computed tomography imaging of the mouse heart (437 views)
Exp Physiol Experimental Physiology (ISSN: 1469-445x, 0958-0670), 2013 Mar; 98(3): 645-651.
Impact Factor: 2.871
View Export to BibTeX Export to EndNote
Giuffrida ML, Tomasello F, Caraci F, Chiechio S, Nicoletti F, Copani A
* Beta-Amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease (665 views)
Mol Neurobiol (ISSN: 0893-7648), 2012 Dec; 46(3): 605-613.
Impact Factor: 5.471
View Export to BibTeX Export to EndNote
De Natale C, Minerva V, Patti L, Mazzarella R, Ciano O, Maione S, Luongo D, Naviglio D, Marotta G, Turco S, Ciati R, Melegari C, Rivellese AA, Riccardi G
* Effects Of Baked Products Enriched With N-3 Fatty Acids, Folates, β -Glucans, And Tocopherol In Patients With Mild Mixed Hyperlipidemia (325 views)
J Am Coll Nutr (ISSN: 1541-1087, 0731-5724), 2012 Oct; 31(5): 311-319.
Impact Factor: 1.738
View Export to BibTeX Export to EndNote
Calabrese V, Cornelius C, Dinkova-Kostova AT, Iavicoli I, Di Paola R, Koverech A, Cuzzocrea S, Rizzarelli E, Calabrese EJ
* Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity (2637 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0925-4439, 1570-9639), 2012 May; 1822(5): 753-783.
Impact Factor: 3.733
View Export to BibTeX Export to EndNote
Pier PM
* RE: Imaging Features of Hepato-Splenic Amyloidosis at PET/CT (283 views)
Korean Journal Of Radiology (ISSN: 1229-6929), 2012 May; 13(3): 368-369.
Impact Factor: 1.555
View Export to BibTeX Export to EndNote
Galdiero S, Vitiello M, Finamore E, Mansi R, Galdiero M, Morelli G, Tesauro D
* Activation of monocytic cells by immunostimulatory lipids conjugated to peptide antigens (366 views)
Molecular Biosystems (ISSN: 1742-206x), 2012; 8(12): 3166-3177.
Impact Factor: 3.35
View Export to BibTeX Export to EndNote
Santulli G, Lombardi A, Sorriento D, Anastasio A, Del Giudice C, Formisano P, Béguinot F, Trimarco B, Miele C, Iaccarino G
* Age-related impairment in insulin release: The essential role of β 2-adrenergic receptor (440 views)
Diabetesdiabetes (ISSN: 0012-1797), 2012; 61(3): 692-701.
Impact Factor: 7.895
View Export to BibTeX Export to EndNote
Esmaeilzadeh M, Kullingsjo J, Ullman H, Varrone A, Tedroff J
* Regional cerebral glucose metabolism after pridopidine (ACR16) treatment in patients with huntington disease (341 views)
Clin Neuropharmacol (ISSN: 0362-5664), 2011 May; 34(3): 95-100.
Impact Factor: 2.166
View Export to BibTeX Export to EndNote
Bozzetto L, Prinster A, Mancini M, Giacco R, De Natale C, Salvatore M, Riccardi G, Rivellese AA, Annuzzi G
* Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution (386 views)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362, 0014-2972linking), 2011 Jan; 41(1): 39-44.
Impact Factor: 3.018
View Export to BibTeX Export to EndNote
Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (458 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Bilo L, Meo R, de Leva MF, Vicidomini C, Salvatore M, Pappata S
* Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: a case report (465 views)
Seizure (ISSN: 1532-2688, 1059-1311), 2010 Apr; 19(3): 198-201.
Impact Factor: 1.649
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (399 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Galdiero S, Galdiero M, Pedone C
* Beta-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly And Interaction With Lipids (399 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2007 Feb; 8(1): 63-82.
Impact Factor: 3.259
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Fiory F, Alberobello AT, Miele C, Oriente F, Esposito I, Corbo V, Ruvo M, Tizzano B, Rasmussen TE, Gammeltoft S, Formisano P, Beguinot F
* Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling (446 views)
Mol Cell Biol (ISSN: 0270-7306, 1098-5549), 2005 Dec; 25(24): 10803-10814.
Impact Factor: 7.093
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (392 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Petretta M, Acampa W, Cuocolo A
* Myocardial viability assessment in regions of left ventricular dysfunction. Part I: Radionuclide imaging and clinical implications (319 views)
Nuclear Medicine Communications (ISSN: 0143-3636, 1473-5628), 2001 Jun; 22(6): 607-611.
Impact Factor: 1.19
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Acampa W, Di Benedetto C, Cuocolo A
An overview of radiotracers in nuclear cardiology (352 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2000 Nov; 7(6): 701-707.
Impact Factor: 1.854
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Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (316 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
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Vinci C, Caltabiano V, Santoro AM, Rabuazzo AM, Buscema M, Purrello R, Rizzarelli E, Vigneri R, Purrello F
Copper Addition Prevents The Inhibitory Effects Of Interleukin 1-Beta On Rat Pancreatic Islets (430 views)
Diabetologia, 1995 Jan; 38(1): 39-45.
Impact Factor: 0
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Greco AM, de Franciscis P, Bozza P, Salvatore M
Thyroid function and lipid metabolism in rats treated with lithium and cholesterol deficient Nath diet (677 views)
Boll Soc Ital Biol Sper (ISSN: 0037-8771), 1979 Dec 30; 55(24): 2589-2595.
Impact Factor: 0
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30 Records (29 excluding Abstracts).
Total impact factor: 95.873 (93.995 excluding Abstracts).
Total 5 year impact factor: 106.123 (104.184 excluding Abstracts).
Total impact factor: 95.873 (93.995 excluding Abstracts).
Total 5 year impact factor: 106.123 (104.184 excluding Abstracts).
597 views. Last view on Tuesday 20 September 2022, 20:07:48
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