Influence of left ventricular asynchrony on systolic and diastolic function in patients with nonischemic heart failure(612 views) Della Morte AM, Storto G, Varrone A, Pace L, Cuocolo A, Perrone-Filardi P, Betocchi S, Chiariello M, Salvatore M
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1998; 96(1-2): 68-72.
Affiliations: Cattedra di Medicina Nucleare, Dipartimento di Scienze Radiologiche, Università Federico II, Napoli, Italy
Centro C N R Medicina Nucleare, Università Federico II, Napoli, Italy
Ist. Med. Int. - Cardiol. C., Facoltà di Medicina, Università Federico II, Napoli, Italy
Istituto Nazionale Tumori, Fondazione Pascale, Via Mariano Semmola, 80131 Napoli NA, Italy
Dipto. Sci. Biomorfologiche F., Facoltà di Medicina, Università Federico II, Via Pansini 5, 80131 Napoli NA, Italy
References: Not available.
Influence of left ventricular asynchrony on systolic and diastolic function in patients with nonischemic heart failure
Introduction. The asynchrony of the left ventricle - ie. its nonuniform contraction and relaxation - is an important factor for left ventricular function. Heart failure is often related to abnormal systolic function, sometimes associated with a diastolic dysfunction. We studied the relationship of left ventricular asynchrony to left ventricular function in patients with nonischemic heart failure. Material and methods. Radionuclide angiography at rest was performed in 25 patients with nonischemic heart failure and in 26 age and sex matched normal subjects. In addition to ejection fraction and peak filling rate, two indices of left ventricular asynchrony were calculated: the coefficient of variation of regional time to end systole and the coefficient of variation of regional time to peak filling rate. These factors indicate how disperse are the regional values of time to end systole and of time to peak filling rate. In fact, the higher the value, the greater the asynchrony. Results. A significant (r=.46, p
Influence of left ventricular asynchrony on systolic and diastolic function in patients with nonischemic heart failure
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