The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (541 views)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Export to BibTeX Export to EndNote
Paper type: Abstract, Conference, Review,
Impact factor: 3.675, 5-year impact factor: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84920155020&partnerID=40&md5=22adb5ce7be3480a808a7b4ec24cf526
Keywords: Amyloid, Calcium, Free Fatty Acids, Genetic Predisposition, Membranes, Obesity, Type Ii Diabetes Mellitus, Calpain 10, Cholesterol, Glucokinase Regulatory Protein, Insulin Receptor, Peptides And Proteins, Somatomedin C, Transcription Factor 7, Unclassified Drug, Article, Biological Phenomena And Functions Concerning The Entire Organism, Calcium Homeostasis, Cell Death, Channel Gating, Cytotoxicity, Dyshomeostasis, Familial Hypercalciuric Hypercalcemia, Gene Mutation, Human, Insulin Resistance, Lipid Membrane, Membrane Damage, Non Insulin Dependent Diabetes Mellitus, Nonhuman, Protein Aggregation, Risk Factor, Weight Gain,
Affiliations:
*** IBB - CNR ***
Istituto CNR di Biostrutture e Bioimmagini-Sezione di CataniaCatania, Italy
Dipartimento di Scienze Chimiche Viale Andrea Doria 6, Università Degli Studi di CataniaCatania, Italy
References:
Chen, L., Magliano, D.J., Zimmet, P.Z., The worldwide epidemiology of type 2 diabetes mellitus -present and future perspectives (2012) Nat Rev Endocrinol, 8, pp. 228-23
Shaw, J.E., Sicree, R.A., Zimmet, P.Z., Global estimates of the prevalence of diabetes for 2010 and 2030 (2010) Diabetes Res Clin Pract, 87, pp. 4-14
Wimalawansa, S.J., Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily (1997) Crit Rev Neurobiol, 11, pp. 167-239
Höppener, J.W.M., Ahrén, B., Lips, C.J.M., Islet amyloid and type 2 diabetes mellitus (2000) N Engl J Med, 343, pp. 411-419
Hull, R.L., Westermark, G.T., Westermark, P., Kahn, S.E., Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes (2004) J Clin Endocrinol Metab, 89, pp. 3629-3643
Aitken, J.F., Loomes, K.M., Scott, D.W., Reddy, S., Phillips, A.R.J., Prijic, G., Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice (2010) Diabetes, 59, pp. 161-171
Knight, J.D., Hebda, J.A., Miranker, A.D., Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide (2006) Biochemistry (Mosc), 45, pp. 9496-9508
Zhang, Y., Luo, Y., Deng, Y., Mu, Y., Wei, G., Lipid interaction and membrane perturbation of human islet amyloid polypeptide monomer and dimer by molecular dynamics simulations (2012) PLoS One, 7
Anguiano, M., Nowak, R.J., Lansbury, P.T., Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes (2002) Biochemistry (Mosc), 41, pp. 11338-11343
Sciacca, M.F.M., Milardi, D., Messina, G.M.L., Marletta, G., Brender, J.R., Ramamoorthy, A., Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP (2013) Biophys J, 104, pp. 173-184
Zhao, J., Hu, R., Sciacca, M.F.M., Brender, J.R., Chen, H., Ramamoorthy, A., Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels (2014) Phys Chem Chem Phys, 16, pp. 2368-2377
Scalisi, S., Sciacca, M.F.M., Zhavnerko, G., Grasso, D.M., Marletta, G., La Rosa, C., Self-assembling pathway of HiApp fibrils within lipid bilayers (2010) Chembiochemistry, 11, pp. 1856-1859
Milardi, D., Sciacca, M.F.M., Pappalardo, M., Grasso, D.M., Rosa, C.L., The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH (2011) Eur Biophys J, 40, pp. 1-12
Pannuzzo, M., Milardi, D., Raudino, A., Karttunen, M., La Rosa, C., Analytical model and multiscale simulations of Aß peptide aggregation in lipid membranes: towards a unifying description of conformational transitions, oligomerization and membrane damage (2013) Phys Chem Chem Phys PCCP, 15, pp. 8940-8951
Sciacca, M.F.M., Kotler, S.A., Brender, J.R., Chen, J., Lee, D., Ramamoorthy, A., Two-step mechanism of membrane disruption by Aß through membrane fragmentation and pore formation (2012) Biophys J, 103, pp. 702-710
Sakagashira, S., Sanke, T., Hanabusa, T., Shimomura, H., Ohagi, S., Kumagaye, K.Y., Missense mutation of amylin gene (S20G) in Japanese NIDDM patients (1996) Diabetes, 45, pp. 1279-1281
Hiddinga, H.J., Sakagashira, S., Ishigame, M., Madde, P., Sanke, T., Nanjo, K., Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance (2012) J Diabetes Investig, 3, pp. 138-147
Ahlqvist, E., Ahluwalia, T.S., Groop, L., Genetics of type 2 diabetes (2011) Clin Chem, 57, pp. 241-254
Choi, J.M., Seo, M-H., Kyeong, H-H., Kim, E., Kim, H-S., Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase (2013) Proc Natl Acad Sci U S A, 110, pp. 10171-10176
Beardsall, K., Vanhaesebrouck, S., Frystyk, J., Ogilvy-Stuart, A.L., Vanhole, C., van Weissenbruch, M., Relationship between insulin-like growth factor I levels, early insulin treatment, and clinical outcomes of very low birth weight infants (2014) J Pediatr, 164, p. 1038. , e-44.e
Horikawa, Y., Oda, N., Cox, N.J., Li, X., Orho-Melander, M., Hara, M., Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus (2000) Nat Genet, 26, pp. 163-175
Chattopadhyay, N., Brown, E.M., (2003) Calcium-Sensing Receptor, , Springer Science & Business Media
Resnick, L.M., Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders (1992) Am J Med, 93, pp. 11S-20S
Barbagallo, M., Gupta, R.K., Resnick, L.M., Cellular ions in NIDDM: relation of calcium to hyperglycemia and cardiac mass (1996) Diabetes Care, 19, pp. 1393-1398
Squier, T.C., Bigelow, D.J., Protein oxidation and age-dependent alterations in calcium homeostasis (2000) Front Biosci J Virtual Libr, 5, pp. D504-D526
Nitahara, J.A., Cheng, W., Liu, Y., Li, B., Leri, A., Li, P., Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats (1998) J Mol Cell Cardiol, 30, pp. 519-535
Astrup, A., The role of calcium in energy balance and obesity: the search for mechanisms (2008) Am J Clin Nutr, 88, pp. 873-874
Rescher, U., Gerke, V., Annexins -unique membrane binding proteins with diverse functions (2004) J Cell Sci, 117, pp. 2631-2639
Gerke, V., Creutz, C.E., Moss, S.E., Annexins: linking Ca2+ signalling to membrane dynamics (2005) Nat Rev Mol Cell Biol, 6, pp. 449-461
Kuczmarski, R.J., Flegal, K.M., Campbell, S.M., Johnson, C.L., Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991 (1994) JAMA J Am Med Assoc, 272, pp. 205-211
Meier, D.T., Morcos, M., Samarasekera, T., Zraika, S., Hull, R.L., Kahn, S.E., Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice (2014) Diabetologia, 57, pp. 1884-1888
Steyn, N.P., Mann, J., Bennett, P.H., Temple, N., Zimmet, P., Tuomilehto, J., Diet, nutrition and the prevention of type 2 diabetes (2004) Public Health Nutr, 7, pp. 147-165
Knowler, W.C., Pettitt, D.J., Savage, P.J., Bennett, P.H., Diabetes incidence in Pima indians: contributions of obesity and parental diabetes (1981) Am J Epidemiol, 113, pp. 144-156
Kahn, S.E., Hull, R.L., Utzschneider, K.M., Mechanisms linking obesity to insulin resistance and type 2 diabetes (2006) Nature, 444, pp. 840-846
Swinburn, B.A., Metcalf, P.A., Ley, S.J., Long-term (5-year) effects of a reduced-fat diet intervention in individuals with glucose intolerance (2001) Diabetes Care, 24, pp. 619-624
Astrup, A., Grunwald, G.K., Melanson, E.L., Saris, W.H., Hill, J.O., The role of low-fat diets in body weight control: a meta-analysis of ad libitum dietary intervention studies (2000) Int J Obes Relat Metab Disord, 24, pp. 1545-1552
Boden, G., Role of fatty acids in the pathogenesis of insulin resistance and NIDDM (1997) Diabetes, 46, pp. 3-10
Boden, G., Chen, X., Ruiz, J., White, J.V., Rossetti, L., Mechanisms of fatty acid-induced inhibition of glucose uptake (1994) J Clin Invest, 93, pp. 2438-2446
Reaven, G.M., Hollenbeck, C., Jeng, C.Y., Wu, M.S., Chen, Y.D., Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM (1988) Diabetes, 37, pp. 1020-1024
Tanner, J.M., The relation between serum cholesterol and physique in healthy young men (1951) J Physiol, 115, pp. 371-390
Montoye, H.J., Epstein, F.H., Kjelsberg, M.O., Relationship between serum cholesterol and body fatness. An epidemiologic study (1966) Am J Clin Nutr, 18, pp. 397-406
Sasahara, K., Morigaki, K., Shinya, K., Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces (2014) FEBS J, 281, pp. 2597-2612
Wakabayashi, M., Matsuzaki, K., Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts (2009) FEBS Lett, 583, pp. 2854-2858
Yang, H., Li, X., The role of fatty acid metabolism and lipotoxicity in pancreatic ß-cell injury: identification of potential therapeutic targets (2012) Acta Pharm Sin B, 2, pp. 396-402
Björntorp, P., Bergman, H., Varnauskas, E., Plasma free fatty acid turnover rate in obesity (1969) Acta Med Scand, 185, pp. 351-356
Ma, Z., Westermark, G.T., Effects of free fatty acid on polymerization of islet amyloid polypeptide (IAPP) in vitro and on amyloid fibril formation in cultivated isolated islets of transgenic mice overexpressing human IAPP (2002) Mol Med, 8, pp. 863-868
Westermark, P., Andersson, A., Westermark, G.T., Islet amyloid polypeptide, islet amyloid, and diabetes mellitus (2011) Physiol Rev, 91, pp. 795-826
MacDonald, M.J., Dobrzyn, A., Ntambi, J., Stoker, S.W., The role of rapid lipogenesis in insulin secretion: insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells (2008) Arch Biochem Biophys, 470, pp. 153-162
Stefani, M., Rigacci, S., Protein folding and aggregation into amyloid: the interference by natural phenolic compounds (2013) Int J Mol Sci, 14, pp. 12411-12457
Shaw, J. E., Sicree, R. A., Zimmet, P. Z., Global estimates of the prevalence of diabetes for 2010 and 2030 (2010) Diabetes Res Clin Pract, 87, pp. 4-14
Wimalawansa, S. J., Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily (1997) Crit Rev Neurobiol, 11, pp. 167-239
H ppener, J. W. M., Ahr n, B., Lips, C. J. M., Islet amyloid and type 2 diabetes mellitus (2000) N Engl J Med, 343, pp. 411-419
Hull, R. L., Westermark, G. T., Westermark, P., Kahn, S. E., Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes (2004) J Clin Endocrinol Metab, 89, pp. 3629-3643
Aitken, J. F., Loomes, K. M., Scott, D. W., Reddy, S., Phillips, A. R. J., Prijic, G., Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice (2010) Diabetes, 59, pp. 161-171
Knight, J. D., Hebda, J. A., Miranker, A. D., Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide (2006) Biochemistry (Mosc), 45, pp. 9496-9508
Sciacca, M. F. M., Milardi, D., Messina, G. M. L., Marletta, G., Brender, J. R., Ramamoorthy, A., Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP (2013) Biophys J, 104, pp. 173-184
Hiddinga, H. J., Sakagashira, S., Ishigame, M., Madde, P., Sanke, T., Nanjo, K., Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance (2012) J Diabetes Investig, 3, pp. 138-147
Choi, J. M., Seo, M-H., Kyeong, H-H., Kim, E., Kim, H-S., Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase (2013) Proc Natl Acad Sci U S A, 110, pp. 10171-10176
Resnick, L. M., Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders (1992) Am J Med, 93, pp. 11S-20S
Squier, T. C., Bigelow, D. J., Protein oxidation and age-dependent alterations in calcium homeostasis (2000) Front Biosci J Virtual Libr, 5, pp. D504-D526
Nitahara, J. A., Cheng, W., Liu, Y., Li, B., Leri, A., Li, P., Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats (1998) J Mol Cell Cardiol, 30, pp. 519-535
Kuczmarski, R. J., Flegal, K. M., Campbell, S. M., Johnson, C. L., Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991 (1994) JAMA J Am Med Assoc, 272, pp. 205-211
Meier, D. T., Morcos, M., Samarasekera, T., Zraika, S., Hull, R. L., Kahn, S. E., Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice (2014) Diabetologia, 57, pp. 1884-1888
Steyn, N. P., Mann, J., Bennett, P. H., Temple, N., Zimmet, P., Tuomilehto, J., Diet, nutrition and the prevention of type 2 diabetes (2004) Public Health Nutr, 7, pp. 147-165
Knowler, W. C., Pettitt, D. J., Savage, P. J., Bennett, P. H., Diabetes incidence in Pima indians: contributions of obesity and parental diabetes (1981) Am J Epidemiol, 113, pp. 144-156
Kahn, S. E., Hull, R. L., Utzschneider, K. M., Mechanisms linking obesity to insulin resistance and type 2 diabetes (2006) Nature, 444, pp. 840-846
Swinburn, B. A., Metcalf, P. A., Ley, S. J., Long-term (5-year) effects of a reduced-fat diet intervention in individuals with glucose intolerance (2001) Diabetes Care, 24, pp. 619-624
Reaven, G. M., Hollenbeck, C., Jeng, C. Y., Wu, M. S., Chen, Y. D., Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM (1988) Diabetes, 37, pp. 1020-1024
Tanner, J. M., The relation between serum cholesterol and physique in healthy young men (1951) J Physiol, 115, pp. 371-390
Montoye, H. J., Epstein, F. H., Kjelsberg, M. O., Relationship between serum cholesterol and body fatness. An epidemiologic study (1966) Am J Clin Nutr, 18, pp. 397-406
Bj rntorp, P., Bergman, H., Varnauskas, E., Plasma free fatty acid turnover rate in obesity (1969) Acta Med Scand, 185, pp. 351-356
MacDonald, M. J., Dobrzyn, A., Ntambi, J., Stoker, S. W., The role of rapid lipogenesis in insulin secretion: insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells (2008) Arch Biochem Biophys, 470, pp. 153-162
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Export to BibTeX Export to EndNote
Paper type: Abstract, Conference, Review,
Impact factor: 3.675, 5-year impact factor: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84920155020&partnerID=40&md5=22adb5ce7be3480a808a7b4ec24cf526
Keywords: Amyloid, Calcium, Free Fatty Acids, Genetic Predisposition, Membranes, Obesity, Type Ii Diabetes Mellitus, Calpain 10, Cholesterol, Glucokinase Regulatory Protein, Insulin Receptor, Peptides And Proteins, Somatomedin C, Transcription Factor 7, Unclassified Drug, Article, Biological Phenomena And Functions Concerning The Entire Organism, Calcium Homeostasis, Cell Death, Channel Gating, Cytotoxicity, Dyshomeostasis, Familial Hypercalciuric Hypercalcemia, Gene Mutation, Human, Insulin Resistance, Lipid Membrane, Membrane Damage, Non Insulin Dependent Diabetes Mellitus, Nonhuman, Protein Aggregation, Risk Factor, Weight Gain,
Affiliations:
*** IBB - CNR ***
Istituto CNR di Biostrutture e Bioimmagini-Sezione di CataniaCatania, Italy
Dipartimento di Scienze Chimiche Viale Andrea Doria 6, Università Degli Studi di CataniaCatania, Italy
References:
Chen, L., Magliano, D.J., Zimmet, P.Z., The worldwide epidemiology of type 2 diabetes mellitus -present and future perspectives (2012) Nat Rev Endocrinol, 8, pp. 228-23
Shaw, J.E., Sicree, R.A., Zimmet, P.Z., Global estimates of the prevalence of diabetes for 2010 and 2030 (2010) Diabetes Res Clin Pract, 87, pp. 4-14
Wimalawansa, S.J., Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily (1997) Crit Rev Neurobiol, 11, pp. 167-239
Höppener, J.W.M., Ahrén, B., Lips, C.J.M., Islet amyloid and type 2 diabetes mellitus (2000) N Engl J Med, 343, pp. 411-419
Hull, R.L., Westermark, G.T., Westermark, P., Kahn, S.E., Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes (2004) J Clin Endocrinol Metab, 89, pp. 3629-3643
Aitken, J.F., Loomes, K.M., Scott, D.W., Reddy, S., Phillips, A.R.J., Prijic, G., Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice (2010) Diabetes, 59, pp. 161-171
Knight, J.D., Hebda, J.A., Miranker, A.D., Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide (2006) Biochemistry (Mosc), 45, pp. 9496-9508
Zhang, Y., Luo, Y., Deng, Y., Mu, Y., Wei, G., Lipid interaction and membrane perturbation of human islet amyloid polypeptide monomer and dimer by molecular dynamics simulations (2012) PLoS One, 7
Anguiano, M., Nowak, R.J., Lansbury, P.T., Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes (2002) Biochemistry (Mosc), 41, pp. 11338-11343
Sciacca, M.F.M., Milardi, D., Messina, G.M.L., Marletta, G., Brender, J.R., Ramamoorthy, A., Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP (2013) Biophys J, 104, pp. 173-184
Zhao, J., Hu, R., Sciacca, M.F.M., Brender, J.R., Chen, H., Ramamoorthy, A., Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels (2014) Phys Chem Chem Phys, 16, pp. 2368-2377
Scalisi, S., Sciacca, M.F.M., Zhavnerko, G., Grasso, D.M., Marletta, G., La Rosa, C., Self-assembling pathway of HiApp fibrils within lipid bilayers (2010) Chembiochemistry, 11, pp. 1856-1859
Milardi, D., Sciacca, M.F.M., Pappalardo, M., Grasso, D.M., Rosa, C.L., The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH (2011) Eur Biophys J, 40, pp. 1-12
Pannuzzo, M., Milardi, D., Raudino, A., Karttunen, M., La Rosa, C., Analytical model and multiscale simulations of Aß peptide aggregation in lipid membranes: towards a unifying description of conformational transitions, oligomerization and membrane damage (2013) Phys Chem Chem Phys PCCP, 15, pp. 8940-8951
Sciacca, M.F.M., Kotler, S.A., Brender, J.R., Chen, J., Lee, D., Ramamoorthy, A., Two-step mechanism of membrane disruption by Aß through membrane fragmentation and pore formation (2012) Biophys J, 103, pp. 702-710
Sakagashira, S., Sanke, T., Hanabusa, T., Shimomura, H., Ohagi, S., Kumagaye, K.Y., Missense mutation of amylin gene (S20G) in Japanese NIDDM patients (1996) Diabetes, 45, pp. 1279-1281
Hiddinga, H.J., Sakagashira, S., Ishigame, M., Madde, P., Sanke, T., Nanjo, K., Expression of wild-type and mutant S20G hIAPP in physiologic knock-in mouse models fails to induce islet amyloid formation, but induces mild glucose intolerance (2012) J Diabetes Investig, 3, pp. 138-147
Ahlqvist, E., Ahluwalia, T.S., Groop, L., Genetics of type 2 diabetes (2011) Clin Chem, 57, pp. 241-254
Choi, J.M., Seo, M-H., Kyeong, H-H., Kim, E., Kim, H-S., Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase (2013) Proc Natl Acad Sci U S A, 110, pp. 10171-10176
Beardsall, K., Vanhaesebrouck, S., Frystyk, J., Ogilvy-Stuart, A.L., Vanhole, C., van Weissenbruch, M., Relationship between insulin-like growth factor I levels, early insulin treatment, and clinical outcomes of very low birth weight infants (2014) J Pediatr, 164, p. 1038. , e-44.e
Horikawa, Y., Oda, N., Cox, N.J., Li, X., Orho-Melander, M., Hara, M., Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus (2000) Nat Genet, 26, pp. 163-175
Chattopadhyay, N., Brown, E.M., (2003) Calcium-Sensing Receptor, , Springer Science & Business Media
Resnick, L.M., Cellular calcium and magnesium metabolism in the pathophysiology and treatment of hypertension and related metabolic disorders (1992) Am J Med, 93, pp. 11S-20S
Barbagallo, M., Gupta, R.K., Resnick, L.M., Cellular ions in NIDDM: relation of calcium to hyperglycemia and cardiac mass (1996) Diabetes Care, 19, pp. 1393-1398
Squier, T.C., Bigelow, D.J., Protein oxidation and age-dependent alterations in calcium homeostasis (2000) Front Biosci J Virtual Libr, 5, pp. D504-D526
Nitahara, J.A., Cheng, W., Liu, Y., Li, B., Leri, A., Li, P., Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats (1998) J Mol Cell Cardiol, 30, pp. 519-535
Astrup, A., The role of calcium in energy balance and obesity: the search for mechanisms (2008) Am J Clin Nutr, 88, pp. 873-874
Rescher, U., Gerke, V., Annexins -unique membrane binding proteins with diverse functions (2004) J Cell Sci, 117, pp. 2631-2639
Gerke, V., Creutz, C.E., Moss, S.E., Annexins: linking Ca2+ signalling to membrane dynamics (2005) Nat Rev Mol Cell Biol, 6, pp. 449-461
Kuczmarski, R.J., Flegal, K.M., Campbell, S.M., Johnson, C.L., Increasing prevalence of overweight among US adults. The National Health and Nutrition Examination Surveys, 1960 to 1991 (1994) JAMA J Am Med Assoc, 272, pp. 205-211
Meier, D.T., Morcos, M., Samarasekera, T., Zraika, S., Hull, R.L., Kahn, S.E., Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice (2014) Diabetologia, 57, pp. 1884-1888
Steyn, N.P., Mann, J., Bennett, P.H., Temple, N., Zimmet, P., Tuomilehto, J., Diet, nutrition and the prevention of type 2 diabetes (2004) Public Health Nutr, 7, pp. 147-165
Knowler, W.C., Pettitt, D.J., Savage, P.J., Bennett, P.H., Diabetes incidence in Pima indians: contributions of obesity and parental diabetes (1981) Am J Epidemiol, 113, pp. 144-156
Kahn, S.E., Hull, R.L., Utzschneider, K.M., Mechanisms linking obesity to insulin resistance and type 2 diabetes (2006) Nature, 444, pp. 840-846
Swinburn, B.A., Metcalf, P.A., Ley, S.J., Long-term (5-year) effects of a reduced-fat diet intervention in individuals with glucose intolerance (2001) Diabetes Care, 24, pp. 619-624
Astrup, A., Grunwald, G.K., Melanson, E.L., Saris, W.H., Hill, J.O., The role of low-fat diets in body weight control: a meta-analysis of ad libitum dietary intervention studies (2000) Int J Obes Relat Metab Disord, 24, pp. 1545-1552
Boden, G., Role of fatty acids in the pathogenesis of insulin resistance and NIDDM (1997) Diabetes, 46, pp. 3-10
Boden, G., Chen, X., Ruiz, J., White, J.V., Rossetti, L., Mechanisms of fatty acid-induced inhibition of glucose uptake (1994) J Clin Invest, 93, pp. 2438-2446
Reaven, G.M., Hollenbeck, C., Jeng, C.Y., Wu, M.S., Chen, Y.D., Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM (1988) Diabetes, 37, pp. 1020-1024
Tanner, J.M., The relation between serum cholesterol and physique in healthy young men (1951) J Physiol, 115, pp. 371-390
Montoye, H.J., Epstein, F.H., Kjelsberg, M.O., Relationship between serum cholesterol and body fatness. An epidemiologic study (1966) Am J Clin Nutr, 18, pp. 397-406
Sasahara, K., Morigaki, K., Shinya, K., Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces (2014) FEBS J, 281, pp. 2597-2612
Wakabayashi, M., Matsuzaki, K., Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts (2009) FEBS Lett, 583, pp. 2854-2858
Yang, H., Li, X., The role of fatty acid metabolism and lipotoxicity in pancreatic ß-cell injury: identification of potential therapeutic targets (2012) Acta Pharm Sin B, 2, pp. 396-402
Björntorp, P., Bergman, H., Varnauskas, E., Plasma free fatty acid turnover rate in obesity (1969) Acta Med Scand, 185, pp. 351-356
Ma, Z., Westermark, G.T., Effects of free fatty acid on polymerization of islet amyloid polypeptide (IAPP) in vitro and on amyloid fibril formation in cultivated isolated islets of transgenic mice overexpressing human IAPP (2002) Mol Med, 8, pp. 863-868
Westermark, P., Andersson, A., Westermark, G.T., Islet amyloid polypeptide, islet amyloid, and diabetes mellitus (2011) Physiol Rev, 91, pp. 795-826
MacDonald, M.J., Dobrzyn, A., Ntambi, J., Stoker, S.W., The role of rapid lipogenesis in insulin secretion: insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells (2008) Arch Biochem Biophys, 470, pp. 153-162
Stefani, M., Rigacci, S., Protein folding and aggregation into amyloid: the interference by natural phenolic compounds (2013) Int J Mol Sci, 14, pp. 12411-12457
Shaw, J. E., Sicree, R. A., Zimmet, P. Z., Global estimates of the prevalence of diabetes for 2010 and 2030 (2010) Diabetes Res Clin Pract, 87, pp. 4-14
Wimalawansa, S. J., Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily (1997) Crit Rev Neurobiol, 11, pp. 167-239
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The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime?
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Palmieri V, Storto G, Arezzi E, Pellegrino T, Mancini M, Di Minno G, Ferrara AL, Cuocolo A, Celentano A
* Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects (311 views)
J Hum Hypertens (ISSN: 0950-9240), 2005 Dec; 19(12): 941-950.
Impact Factor: 2.405
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (350 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Criscuolo C, Mancini P, Menchise V, Sacca F, De Michele G, Banfi S, Filla A
* Very late onset in ataxia oculomotor apraxia type I [1] (330 views)
Ann Neurol (ISSN: 0364-5134), 2005 May; 57(5): 777-777.
Impact Factor: 7.571
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Spagnuolo MS, Cigliano L, D'Andrea LD, Pedone C, Abrescia P
* Assignment of the binding site for haptoglobin on apolipoprotein A-I (479 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Jan 14; 280(2): 1193-1198.
Impact Factor: 5.854
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Maurea S, Salvatore M
* I-131 Nor-Cholesterol Nuclear imaging in Patients with Hypersecreting or Non-Hypersecreting Adrenal Adenomas (348 views)
Trends In Cholesterol Research, 2005; N/D: N/D-N/D.
Impact Factor: 0
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (486 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (349 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
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Clemente G, Mancini M, Nazzaro F, Lasorella G, Rivieccio A, Palumbo AM, Rivellese AA, Ferrara L, Giacco R
* Effects of different dairy products on postprandial lipemia (918 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2003 Dec; 13(6): 377-383.
Impact Factor: 2.148
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (611 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
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Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (379 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Maurea S, Klain M, Mainolfi C, Ziviello M, Salvatore M
* The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses (269 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2001 Jun; 42(6): 884-892.
Impact Factor: 4.51
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (443 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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De Simone G, Galdiero S, Manco G, Lang D, Rossi M, Pedone C
A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase (574 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Nov 10; 303(5): 761-771.
Impact Factor: 5.388
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Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (375 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (284 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Postiglione A, Nappi A, Brunetti A, Soricelli A, Rubba P, Gnasso A, Cammisa M, Frusciante V, Cortese C, Salvatore M
Relative protection from cerebral atherosclerosis of young patients with homozygous familial hypercholesterolemia (316 views)
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 1991 Sep; 90(1): 23-30.
Impact Factor: 2.889
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (600 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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Trischitta V, Benzi L, Brunetti A, Cecchetti P, Marchetti P, Vigneri R, Navalesi R
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus (971 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1987 May; 64(5): 914-920.
Impact Factor: 4.575
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Greco AM, de Franciscis P, Bozza P, Salvatore M
Thyroid function and lipid metabolism in rats treated with lithium and cholesterol deficient Nath diet (685 views)
Boll Soc Ital Biol Sper (ISSN: 0037-8771), 1979 Dec 30; 55(24): 2589-2595.
Impact Factor: 0
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* Daily Fructose Traces Intake and Liver Injury in Children with Hereditary Fructose Intolerance (189 views) (PDF 90 views)
Nutrients (ISSN: 2072-6643linking, 2072-6643electronic), 2019 Oct 07; 11(10): N/D-N/D.
Impact Factor: 4.171
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Klisic A, Abenavoli L, Fagoonee S, Kavaric N, Kocic G, Ninic A
* Older age and HDL-cholesterol as independent predictors of liver fibrosis assessed by BARD score (184 views)
Hepatology (ISSN: 0026-4806linking, 1827-1669electronic), 2019 Jun; 110(3): 191-198.
Impact Factor: 2.863
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Calvanese L, D'Auria G, Vangone A, Falcigno L, Oliva R
* Structural Basis for Mutations of Human Aquaporins Associated to Genetic Diseases (227 views)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2018 May 25; 19(6): N/D-N/D.
Impact Factor: 3.687
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Ferrucci V, De Antonellis P, Pennino FP, Asadzadeh F, Virgilio A, Montanaro D, Galeone A, Boffa I, Pisano I, Scognamiglio I, Navas L, Diana D, Pedone E, Gargiulo S, Gramanzini M, Brunetti A, Danielson L, Carotenuto M, Liguori L, Verrico A, Quaglietta L, Errico ME, Del Monaco V, D'Argenio V, Tirone F, Mastronuzzi A, Donofrio V, Giangaspero F, Picard D, Remke M, Garzia L, Daniels C, Delattre O, Swartling FJ, Weiss WA, Salvatore F, Fattorusso R, Chesler L, Taylor MD, Cinalli G, Zollo M
* Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1-TGF-beta-OTX2-SNAIL via PTEN inhibition (930 views)
Brain (ISSN: 1460-2156electronic, 0006-8950linking), 2018 May 1; 141(5): 1300-1319.
Impact Factor: 9.915
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Sciacca MFM, Tempra C, Scollo F, Milardi D, La Rosa C
* Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Abeta and hIAPP (232 views) (PDF 107 views)
Bba-Gen Subjects (ISSN: 0005-2736print, 0005-2736linking), 2018 Mar 1; N/D: 1625-1638.
Impact Factor: 4.647
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Zampella E, Acampa W, Assante R, Nappi C, Gaudieri V, Mainolfi CG, Green R, Cantoni V, Panico M, Klain M, Petretta M, Slomka PJ, Cuocolo A
* Combined evaluation of regional coronary artery calcium and myocardial perfusion by (82)Rb PET/CT in the identification of obstructive coronary artery disease (460 views)
Eur J Nucl Med (ISSN: 1619-7089electronic, 1619-7070linking, 1619-7070print), 2018 Jan 25; 45(4): 521-529.
Impact Factor: 5.036
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Nappi C, Gaudieri V, Acampa W, Assante R, Zampella E, Mainolfi CG, Petretta M, Germano G, Cuocolo A
* Comparison of left ventricular shape by gated SPECT imaging in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis (589 views)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017 Aug 14; 25(2): 394-403.
Impact Factor: 4.011
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Sacchi S, Cappelletti P, Pirone L, Smaldone G, Pedone E, Pollegioni L
* Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility (358 views)
Febs Lett (ISSN: 1873-3468, 0014-5793, 0014-5793print), 2017 Feb; 591(4): 646-655.
Impact Factor: 2.999
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Nicastro MC, Spigolon D, Librizzi F, Moran O, Ortore MG, Bulone D, Biagio PLS, Carrotta R
* Amyloid β-peptide insertion in liposomes containing GM1-cholesterol domains (363 views)
Biophys Chem (ISSN: 0301-4622, 0301-4622linking), 2016; 208: 9-16.
Impact Factor: 2.402
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Ringhieri P, Avitabile C, Saviano M, Morelli G, Romanelli A, Accardo A
* The influence of liposomal formulation on the incorporation and retention of PNA oligomers (183 views)
Colloid Surface B (ISSN: 0927-7765), 2016; 145: 462-469.
Impact Factor: 3.887
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Vitiello G, Falanga A, Petruk AA, Merlino A, Fragneto G, Paduano L, Galdiero S, D'Errico G
* Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism (381 views)
Soft Matter (ISSN: 1744-683x), 2015; 11(15): 3003-3016.
Impact Factor: 3.798
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Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (456 views)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
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Ruggiero L, Fiorillo C, Tessa A, Manganelli F, Iodice R, Dubbioso R, Vitale F, Storti E, Soscia E, Santorelli F, Santoro L
* Muscle fiber type disproportion (FTD) in a family with mutations in the LMNA gene (332 views)
Muscle Nerve (ISSN: 0148-639x), 2015; 51(4): 604-608.
Impact Factor: 2.713
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Maurea S, Mainenti PP, Romeo V, Mollica C, Salvatore M
* Nuclear imaging to characterize adrenal tumors: Comparison with MRI (271 views)
World J Radiol (ISSN: 1949-8470, 1949-8470electronic, 1949-8470linking), 2014 Jul 28; 6(7): 493-501.
Impact Factor: 0.567
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Petruk AA, Varriale S, Coscia MR, Mazzarella L, Merlino A, Oreste U
* The Structure Of The Cd3 Zeta Zeta Transmembrane Dimer In Popc And Raft-Like Lipid Bilayer: A Molecular Dynamics Study (442 views)
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Impact Factor: 3.498
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (388 views)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Spagnuolo MS, Di Stasi R, De Rosa L, Maresca B, Cigliano L, D'Andrea LD
* Analysis of the haptoglobin binding region on the apolipoprotein A-I-derived P2a peptide (376 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 220-226.
Impact Factor: 1.862
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Pacelli R, Conson M, Cella L, Liuzzi R, Troncone G, Iorio V, Solla R, Farella A, Scala S, Pagliarulo C, Salvatore M
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J Rad Res Journal Of Radiation Research (ISSN: 1349-9157, 0449-3060, 1349-9157electronic), 2013 Mar 1; 54(2): 292-298.
Impact Factor: 1.691
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Vitiello G, Fragneto G, Petruk AA, Falanga A, Galdiero S, D'Ursi A, Merlino A, D'Errico G
* Cholesterol modulates the fusogenic activity of a membranotropic domain of the FIV glycoprotein gp36 (410 views)
Soft Matter (ISSN: 1744-683x), 2013; 9(28): 6442-6456.
Impact Factor: 4.151
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Ciccarelli M, Sorriento D, Franco A, Fusco A, Del Giudice C, Annunziata R, Cipolletta E, Monti MG, Dorn GW, Trimarco B, Iaccarino G
* Endothelial G protein-coupled receptor kinase 2 regulates vascular homeostasis through the control of free radical oxygen species (461 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 2013; 33(10): 2415-2424.
Impact Factor: 5.533
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De Natale C, Minerva V, Patti L, Mazzarella R, Ciano O, Maione S, Luongo D, Naviglio D, Marotta G, Turco S, Ciati R, Melegari C, Rivellese AA, Riccardi G
* Effects Of Baked Products Enriched With N-3 Fatty Acids, Folates, β -Glucans, And Tocopherol In Patients With Mild Mixed Hyperlipidemia (437 views)
J Am Coll Nutr (ISSN: 1541-1087, 0731-5724), 2012 Oct; 31(5): 311-319.
Impact Factor: 1.738
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Perrone-Filardi P, Musella F, Savarese G, Cecere M, Marciano C, Scala O, Rengo G, Dellegrottaglie S, Cuocolo A, Leosco D
* Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification (439 views)
Eur Heart J-Card Img (ISSN: 2047-2412, 2047-2404, 2047-2412electronic), 2012 Jun; 13(6): 453-458.
Impact Factor: 3.669
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Bucci M, Cigliano L, Vellecco V, D'Andrea LD, Ziaco B, Rossi A, Sautebin L, Carlucci A, Abrescia P, Pedone C, Ianaro A, Cirino G
* Apolipoprotein A-I (ApoA-I) mimetic peptide P2a by restoring cholesterol esterification unmasks ApoA-I anti-inflammatory endogenous activity in vivo (401 views)
J Pharmacol Exp Ther (ISSN: 1521-0103, 0022-3565), 2012 Mar; 340(3): 716-722.
Impact Factor: 3.891
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Acampa W, Petretta M, Evangelista L, Daniele S, Xhoxhi E, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Cuocolo A
* Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial (430 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Mar; 39(3): 387-395.
Impact Factor: 5.114
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Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G
* CaMK4 gene deletion induces hypertension (349 views)
J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D.
Impact Factor: 2.882
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Vitiello G, Falanga A, Galdiero M, Marsh D, Galdiero S, D'Errico G
* Lipid composition modulates the interaction of peptides deriving from herpes simplex virus type I glycoproteins B and H with biomembranes (594 views)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Oct; 1808(10): 2517-2526.
Impact Factor: 3.99
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Maurea S, Imbriaco M, Mollica C, Pace L, Salvatore M
* Quantitative Imaging Characterization Of Hypersecreting Or Non-Hypersecreting Adrenal Adenomas: Comparison Between Iodine-131 Nor-Cholesterol Uptake And Magnetic Resonance Signal Intensity Ratios (284 views)
Nuclear Medicine Communications (ISSN: 1473-5628, 0143-3636), 2011 Jun; 32(6): 535-541.
Impact Factor: 1.404
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (377 views)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
* Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy (559 views)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Apr; 16(4): 450-454.
Impact Factor: 4.23
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Bruni AC, Bernardi L, Colao R, Rubino E, Smirne N, Frangipane F, Terni B, Curcio SA, Mirabelli M, Clodomiro A, Di Lorenzo R, Maletta R, Anfossi M, Gallo M, Geracitano S, Tomaino C, Muraca MG, Leotta A, Lio SG, Pinessi L, Rainero I, Sorbi S, Nee L, Milan G, Pappata S, Postiglione A, Abbamondi N, Forloni G, St George Hyslop P, Rogaeva E, Bugiani O, Giaccone G, Foncin JF, Spillantini MG, Puccio G
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Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2010 Mar 9; 74(10): 798-806.
Impact Factor: 8.017
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De Leva MF, Filla A, Criscuolo C, Tessa A, Pappata S, Quarantelli M, Bilo L, Peluso S, Antenora A, Longo DL, Santorelli FM, De Michele G
* Complex phenotype in an Italian family with a novel mutation in SPG3A (740 views)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2010 Mar; 257(3): 328-331.
Impact Factor: 3.853
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Giacco R, Clemente G, Cipriano D, Luongo D, Viscovo D, Patti L, Di Marino L, Giacco A, Naviglio D, Bianchi MA, Ciati R, Brighenti F, Rivellese AA, Riccardi G
* Effects of the regular consumption of wholemeal wheat foods on cardiovascular risk factors in healthy people (664 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2010 Mar; 20(3): 186-194.
Impact Factor: 3.438
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Galdiero S, Falanga A, Vitiello G, Vitiello M, Pedone C, D'Errico G, Galdiero M
* Role of membranotropic sequences from herpes simplex virus type I glycoproteins B and H in the fusion process (555 views)
Bba-Gen Subjects (ISSN: 0006-3002, 0005-2736, 0925-4439), 2010 Mar; 1798(3): 579-591.
Impact Factor: 4.647
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (410 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Milardi D, Pappalardo M, Grasso DM, La Rosa C
* Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: A computational study (337 views)
Mol Biosyst (ISSN: 1742-206x), 2010; 6(6): 1032-1039.
Impact Factor: 3.825
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Cigliano L, Pugliese CR, Spagnuolo MS, Palumbo R, Abrescia P
* Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes (396 views)
Febs J (ISSN: 1742-464x), 2009 Nov; 276(21): 6158-6171.
Impact Factor: 3.042
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Criscuolo C, Filla A, Coppola G, Rinaldi C, Carbone R, Pinto S, Wang Q, De Leva MF, Salvatore E, Banfi S, Brunetti A, Quarantelli M, Geschwind DH, Pappata S, De Michele G
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J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2009 Sep; 256(8): 1252-1257.
Impact Factor: 2.903
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De Rosa A, Criscuolo C, Mancini P, De Martino M, Giordano IA, Pappata S, Filla A, De Michele G
* Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy (257 views)
Parkinsonism Relat D (ISSN: 1353-8020print, 1353-8020linking, 1873-5126electronic), 2009 Mar; 15(3): 242-244.
Impact Factor: 2.406
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Maurea S, Soricelli A, Salvatore M
* Characterization of hypersecreting or non-hypersecreting adrenal adenomas: Comparison between iodine-131 nor-cholesterol scintigraphy and magnetic resonance imaging (315 views) (PDF 247 views)
Curr Radiopharm (ISSN: 1874-4710, 1874-4729), 2009; 2(1): 56-62.
Impact Factor: 0.643
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Cigliano L, Pugliese CR, Spagnuolo MS, Palumbo R, Abrescia P
* Haptoglobin Binds The Anti-Atherogenic Protein Apolipoprotein E: Impairment Of The Apolipoprotein E Stimulation On Both The Enzyme Lecithin-Cholesterol Acyl-Transferase Activity And The Cholesterol Uptake By Hepatocytes (274 views)
Febs J, 2009; 276: 6158-6171.
Impact Factor: 3.986
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Cigliano L, D'Andrea LD, Maresca B, Serino M, Carlucci A, Salvatore A, Spagnuolo MS, Scigliuolo G, Pedone C, Abrescia P
* Relevance of the amino acid conversions L144R (Zaragoza) and L159P (Zavalla) in the apolipoprotein A-I binding site for haptoglobin (393 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 2008 Nov; 389(11): 1421-1426.
Impact Factor: 3.035
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Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (962 views)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
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Daniele A, Cardillo G, Pennino C, Carbone MT, Scognamiglio D, Esposito L, Correra A, Castaldo G, Zagari A, Salvatore F
* Five human phenylalanine hydroxylase proteins identified in mild hyperphenylalaninemia patients are disease-causing variants (358 views)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2008 Jun; 1782(6): 378-384.
Impact Factor: 2.233
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (401 views)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (407 views)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
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Ntziachristos V, Cuénod CA, Fournier L, Balvay D, Pradel C, Siauve N, Clement O, Jouannot E, Lucidarme O, Vecchio SD, Salvatore M, Law B, Tung C-H, Jain RK, Fukumura D, Munn LL, Brown EB, Schellenberger E, Montet X, Weissleder R, Clerck ND, Postnov A
* Tumor Imaging (350 views)
Textbook Of In Vivo Imaging In Vertebrates (ISSN: 9780-4700), 2007 Jul 16; 1: 277-309.
Impact Factor: 1.148
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Galdiero S, Galdiero M, Pedone C
* Beta-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly And Interaction With Lipids (438 views)
Curr Protein Pept Sci (ISSN: 1389-2037, 1389-2037linking), 2007 Feb; 8(1): 63-82.
Impact Factor: 3.259
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Bosco P, Caraci F, Copani A, Spada R, Sortino M, Salluzzo R, Salemi M, Nicoletti F, Ferri R
* The CDC2 I-G-T haplotype associated with the APOE ε4 allele increases the risk of sporadic Alzheimer's disease in Sicily (372 views)
Neurosci Lett (ISSN: 0304-3940), 2007; 419(3): 195-198.
Impact Factor: 2.085
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Palmieri V, Storto G, Arezzi E, Pellegrino T, Mancini M, Di Minno G, Ferrara AL, Cuocolo A, Celentano A
* Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects (311 views)
J Hum Hypertens (ISSN: 0950-9240), 2005 Dec; 19(12): 941-950.
Impact Factor: 2.405
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (422 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (350 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Criscuolo C, Mancini P, Menchise V, Sacca F, De Michele G, Banfi S, Filla A
* Very late onset in ataxia oculomotor apraxia type I [1] (330 views)
Ann Neurol (ISSN: 0364-5134), 2005 May; 57(5): 777-777.
Impact Factor: 7.571
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Spagnuolo MS, Cigliano L, D'Andrea LD, Pedone C, Abrescia P
* Assignment of the binding site for haptoglobin on apolipoprotein A-I (479 views)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Jan 14; 280(2): 1193-1198.
Impact Factor: 5.854
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Maurea S, Salvatore M
* I-131 Nor-Cholesterol Nuclear imaging in Patients with Hypersecreting or Non-Hypersecreting Adrenal Adenomas (348 views)
Trends In Cholesterol Research, 2005; N/D: N/D-N/D.
Impact Factor: 0
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (486 views)
Clin Nutr (ISSN: 0261-5614, 0261-5614linking), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (349 views) (PDF 247 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
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Clemente G, Mancini M, Nazzaro F, Lasorella G, Rivieccio A, Palumbo AM, Rivellese AA, Ferrara L, Giacco R
* Effects of different dairy products on postprandial lipemia (918 views)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2003 Dec; 13(6): 377-383.
Impact Factor: 2.148
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Pauciullo P, Giannino A, De Michele M, Gentile M, Liguori R, Argiriou A, Carlotto A, Faccenda F, Mancini M, Bond MG, De Simone V, Rubba P
* Increased carotid artery intima-media thickness is associated with a novel mutation of low-density lipoprotein receptor independently of major cardiovascular risk factors (611 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 2003; 52(11): 1433-1438.
Impact Factor: 2.013
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Colao A, Di Somma C, Pivonello R, Cuocolo A, Spinelli L, Bonaduce D, Salvatore M, Lombardi G
* The cardiovascular risk of adult GH deficiency (GHD) improved after GH replacement and worsened in untreated GHD: A 12-month prospective study (379 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2002 Mar; 87(3): 1088-1093.
Impact Factor: 5.199
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Maurea S, Klain M, Mainolfi C, Ziviello M, Salvatore M
* The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses (269 views) (PDF 247 views)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2001 Jun; 42(6): 884-892.
Impact Factor: 4.51
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Tedesco N, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Improved cardiovascular risk factors and cardiac performance after 12 months of growth hormone (GH) replacement in young adult patients, with GH deficiency (443 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 May; 86(5): 1874-1881.
Impact Factor: 5.16
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De Simone G, Galdiero S, Manco G, Lang D, Rossi M, Pedone C
A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase (574 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Nov 10; 303(5): 761-771.
Impact Factor: 5.388
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Marotta T, Ferrara LA, Di Marino L, Mancini M, Annuzzi G, Russo O, D'Orta G, Lucarelli C, Rossi F
Factors affecting lipoprotein lipase in hypertensive patients (375 views)
Metab Clin Exp (ISSN: 0026-0495, 1532-8600), 1995 Jun; 44(6): 712-718.
Impact Factor: 1.681
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (284 views)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Postiglione A, Nappi A, Brunetti A, Soricelli A, Rubba P, Gnasso A, Cammisa M, Frusciante V, Cortese C, Salvatore M
Relative protection from cerebral atherosclerosis of young patients with homozygous familial hypercholesterolemia (316 views)
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 1991 Sep; 90(1): 23-30.
Impact Factor: 2.889
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (600 views)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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Trischitta V, Benzi L, Brunetti A, Cecchetti P, Marchetti P, Vigneri R, Navalesi R
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus (971 views)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1987 May; 64(5): 914-920.
Impact Factor: 4.575
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Greco AM, de Franciscis P, Bozza P, Salvatore M
Thyroid function and lipid metabolism in rats treated with lithium and cholesterol deficient Nath diet (685 views)
Boll Soc Ital Biol Sper (ISSN: 0037-8771), 1979 Dec 30; 55(24): 2589-2595.
Impact Factor: 0
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68 Records (66 excluding Abstracts).
Total impact factor: 233.734 (226.163 excluding Abstracts).
Total 5 year impact factor: 237.72 (226.367 excluding Abstracts).
Total impact factor: 233.734 (226.163 excluding Abstracts).
Total 5 year impact factor: 237.72 (226.367 excluding Abstracts).
541 views. Last view on Monday 27 March 2023, 17:34:00
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