A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose(754 views) Cucinotta V, Grasso G, Pedotti S, Rizzarelli E, Vecchio G, Di Blasio B, Isernia C, Saviano M, Pedone C
Affiliations: Dipto. di Scienza degli Alimenti, Universita' di Napoli Federico II, Via Universita' 100, 80055 Portici, Napoli, Italy
Istituto per lo Studio, Sostanze Naturali Interesse A./C.F., CNR, v.le A. Doria 6, Catania, Italy
Dipartimento di Scienze Chimiche, Universita' di Catania, V.le A. Doria 8, 95125 Catania, Italy
Facoltà di Scienze Ambientali, Seconda Università di Napoli, via Arena, 22, Caserta, Italy
Biocrystallography Research Centre, CNR, Univ. Federico II di Napoli, via Mezzocannone 4, 1-80134 Naples, Italy
Facolt di Scienze Ambientali, Seconda Universit di Napoli, via Arena, 22, Caserta, Italy
References: Not available.
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose
The new platinum(II) complex of 6A,6B-diamino-6A,6B-dideoxycyclomaltoheptaose was synthesized and characterized by spectroscopy (NMR, FAB MS, UV, c.d.) and X-ray diffraction analysis. The complex crystallizes in the ortorhombic space group P212121 with a = 26.970(2), b = 15.102(2), and c = 16.142(2) Å. The Pt(II) has a square-planar coordination with two chlorine atoms and two amino groups in a cis disposition. The complexation with the Pt(II) induces a distortion of the cavity. The hydrogen bonds on the secondary hydroxyl groups, which involve the functionalized rings, are longer and consequently weaker than the other hydrogen bonds.
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose
Malvindi MA, Greco A, Conversano F, Figuerola A, Corti M, Bonora M, Lascialfari A, Doumari HA, Moscardini M, Cingolani R, Gigli G, Casciaro S, Pellegrino T, Ragusa A * MR Contrast Agents(366 views) Small Animal Imaging, 2011 Jul 8; 21(13): 2548-2555. Impact Factor:1.784 ViewExport to BibTeXExport to EndNote