Keywords: 2 Benzylsulfinylbenzoic Acid, Carbonate Dehydratase Ii, Carbonate Dehydratase Inhibitor, Carboxylic Acid, Hydrogen, Unclassified Drug, Article, Binding Affinity, Chemical Structure, Conformation, Crystallization, Enzyme Active Site, Hydrogen Bond, Inhibition Kinetics, Binding Site, Chemistry, Human, Metabolism, Molecular Docking, X Ray Crystallography, Carbonic Anhydrase Ii, Carbonic Anhydrase Inhibitors, Catalytic Domain, X-Ray, Models, Molecular Docking Simulation,
Affiliations: *** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, CNR, Via Mezzocannone 16Naples, Italy
Dipartimento di Chimica e Tecnologie Del Farmaco, Sapienza University of Rome, P.le A. Moro 5Rome, Italy
Universitá Degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica Rm. 188, Via della Lastruccia 3Sesto Fiorentino Florence, Italy
NEUROFARBA Department, Sezione di Scienze Farmaceutiche, Via Ugo Schiff 6Sesto Fiorentino Florence, Italy
Universit Degli Studi di Firenze, Polo Scientifico, Laboratorio di Chimica Bioinorganica Rm. 188, Via della Lastruccia 3Sesto Fiorentino Florence, Italy
References: Not available.
Out of the active site binding pocket for carbonic anhydrase inhibitors
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(418 views) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 ViewExport to BibTeXExport to EndNote